| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Pandey, S Pradhan, B Mitta. LRP-associated protein gene (LRPAP1) and susceptibility to degenerative dementia. Genes, brain, and behavior. vol 7. issue 8. 2009-02-27. PMID:18721259. |
our study suggests that lrpap1-d and apoe e4 alleles significantly increase the susceptibility to degenerative dementias. |
2009-02-27 |
2023-08-12 |
Not clear |
| Nicole Helbecque, Dominique Cottel, Philippe Amouye. Low-density lipoprotein receptor-related protein 8 gene polymorphisms and dementia. Neurobiology of aging. vol 30. issue 2. 2009-02-19. PMID:17614163. |
here we tested in two independent population samples a possible impact of another receptor for apoe, namely the low-density lipoprotein receptor-related protein 8 (lrp8), on the risk of dementia. |
2009-02-19 |
2023-08-12 |
human |
| John Attia, John P A Ioannidis, Ammarin Thakkinstian, Mark McEvoy, Rodney J Scott, Cosetta Minelli, John Thompson, Claire Infante-Rivard, Gordon Guyat. How to use an article about genetic association: A: Background concepts. JAMA. vol 301. issue 1. 2009-01-13. PMID:19126812. |
we use the apoe polymorphism and its association with dementia as a case study to demonstrate the concepts and introduce the terminology used in this field. |
2009-01-13 |
2023-08-12 |
Not clear |
| H Luukinen, J Jokelainen, K Kervinen, Y A Kesäniemi, S Winqvist, M Hillbo. Risk of dementia associated with the ApoE epsilon4 allele and falls causing head injury without explicit traumatic brain injury. Acta neurologica Scandinavica. vol 118. issue 3. 2008-12-01. PMID:18307571. |
risk of dementia associated with the apoe epsilon4 allele and falls causing head injury without explicit traumatic brain injury. |
2008-12-01 |
2023-08-12 |
Not clear |
| H Luukinen, J Jokelainen, K Kervinen, Y A Kesäniemi, S Winqvist, M Hillbo. Risk of dementia associated with the ApoE epsilon4 allele and falls causing head injury without explicit traumatic brain injury. Acta neurologica Scandinavica. vol 118. issue 3. 2008-12-01. PMID:18307571. |
severe head injury (hi) and the apolipoprotein e (apoe) epsilon4 allele are risk factors for dementia. |
2008-12-01 |
2023-08-12 |
Not clear |
| James A Mortimer, David A Snowdon, William R Markesber. Small head circumference is associated with less education in persons at risk for Alzheimer disease in later life. Alzheimer disease and associated disorders. vol 22. issue 3. 2008-11-18. PMID:18580587. |
modification of this association was studied by comparing those with and without evidence of increased ad risk, including possession of apolipoprotein e (apoe)-epsilon 4 alleles, occurrence of dementia before death, and satisfaction of ad neuropathologic criteria at autopsy. |
2008-11-18 |
2023-08-12 |
Not clear |
| Raj N Kalaria, Gladys E Maestre, Raul Arizaga, Robert P Friedland, Doug Galasko, Kathleen Hall, José A Luchsinger, Adesola Ogunniyi, Elaine K Perry, Felix Potocnik, Martin Prince, Robert Stewart, Anders Wimo, Zhen-Xin Zhang, Piero Antuon. Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. The Lancet. Neurology. vol 7. issue 9. 2008-10-03. PMID:18667359. |
the apoe epsilon4 allele does not influence dementia progression in sub-saharan africans. |
2008-10-03 |
2023-08-12 |
human |
| Fumiko Irie, Kamal H Masaki, Helen Petrovitch, Robert D Abbott, G Webster Ross, Dennis R Taaffe, Lenore J Launer, Lon R Whit. Apolipoprotein E epsilon4 allele genotype and the effect of depressive symptoms on the risk of dementia in men: the Honolulu-Asia Aging Study. Archives of general psychiatry. vol 65. issue 8. 2008-08-15. PMID:18678795. |
however, the possible effect of the apoe genotype on the association between depression and dementia is unexamined. |
2008-08-15 |
2023-08-12 |
Not clear |
| Alexandra J Fiocco, Judes Poirier, Ridha Joober, N P V Nair, Sonia J Lupie. Acute and long-term associations between ApoE genetic polymorphism, cortisol levels, and declarative memory performance in older adults. Psychoneuroendocrinology. vol 33. issue 5. 2008-07-08. PMID:18374494. |
to date, only one study has reported a relationship between apoe status and cortisol levels, however the relationship was only found to be significant in dementia patients, with a trend observed in healthy controls. |
2008-07-08 |
2023-08-12 |
Not clear |
| Piotr Lewczuk, Johannes Kornhuber, Hugo Vanderstichele, Eugeen Vanmechelen, Hermann Esselmann, Mirko Bibl, Stefanie Wolf, Markus Otto, Udo Reulbach, Heike Kölsch, Frank Jessen, Johannes Schröder, Peter Schönknecht, Harald Hampel, Oliver Peters, Erik Weimer, Robert Perneczky, Holger Jahn, Christian Luckhaus, Ulrich Lamla, Tillmann Supprian, Juan Manuel Maler, Jens Wiltfan. Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17239996. |
concentration of biomarkers of alzheimer's disease in cerebrospinal fluid (csf) was measured with multiplexing technology (n=223), and compared to the results of elisa assays in patients with early dementias or mild cognitive impairment (mci) collected at 12 gerontopsychiatric university departments, and apoe genotyping was performed. |
2008-06-20 |
2023-08-12 |
human |
| A M W Coppus, H M Evenhuis, G-J Verberne, F E Visser, A Arias-Vasquez, F A Sayed-Tabatabaei, J Vergeer-Drop, P Eikelenboom, W A van Gool, C M van Duij. The impact of apolipoprotein E on dementia in persons with Down's syndrome. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17250929. |
apolipoprotein e (apoe) is consistently associated with dementia in the general population. |
2008-06-20 |
2023-08-12 |
Not clear |
| A M W Coppus, H M Evenhuis, G-J Verberne, F E Visser, A Arias-Vasquez, F A Sayed-Tabatabaei, J Vergeer-Drop, P Eikelenboom, W A van Gool, C M van Duij. The impact of apolipoprotein E on dementia in persons with Down's syndrome. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17250929. |
we studied the effects of apoe on mortality and dementia in a longitudinal prospective study of a large population-based sample of persons with ds (n=425), demented and non-demented. |
2008-06-20 |
2023-08-12 |
Not clear |
| A M W Coppus, H M Evenhuis, G-J Verberne, F E Visser, A Arias-Vasquez, F A Sayed-Tabatabaei, J Vergeer-Drop, P Eikelenboom, W A van Gool, C M van Duij. The impact of apolipoprotein E on dementia in persons with Down's syndrome. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17250929. |
when pooling our data in a meta-analysis, the apoe epsilon4 allele shows a 1.59-fold (95%ci: 1.19-2.12) increase in risk of dementia in persons with ds. |
2008-06-20 |
2023-08-12 |
Not clear |
| A M W Coppus, H M Evenhuis, G-J Verberne, F E Visser, A Arias-Vasquez, F A Sayed-Tabatabaei, J Vergeer-Drop, P Eikelenboom, W A van Gool, C M van Duij. The impact of apolipoprotein E on dementia in persons with Down's syndrome. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17250929. |
we conclude that apoe is influencing the risk of dementia in persons with ds. |
2008-06-20 |
2023-08-12 |
Not clear |
| Paul R Borghesani, L Clark Johnson, Amy L Shelton, Elaine R Peskind, Elizabeth H Aylward, Gerard D Schellenberg, Monique M Cherrie. Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers. Neurobiology of aging. vol 29. issue 7. 2008-06-20. PMID:17350142. |
reduced task-associated mtl activation that does not correlate with either visuospatial perspective or task performance suggests that mtl dysregulation occurs prior to clinical symptoms of dementia in apoe*4 carriers. |
2008-06-20 |
2023-08-12 |
human |
| Ki Woong Kim, Jong-Chul Youn, Moon-Ku Han, Nam Jong Paik, Tae Joo Lee, Joon Hyuk Park, Seok Bum Lee, Il Han Choo, Dong Young Lee, Jin Hyeong Jhoo, Jong Inn Wo. Lack of association between apolipoprotein E polymorphism and vascular dementia in Koreans. Journal of geriatric psychiatry and neurology. vol 21. issue 1. 2008-05-13. PMID:18287165. |
to investigate an association of vascular dementia (vd) with the apolipoprotein e (apoe) polymorphism, the apoe polymorphism of 100 vd patients, 100 age- and gender-matched alzheimer disease (ad) patients, and 200 age- and gender-matched nondemented control (nc) subjects was genotyped. |
2008-05-13 |
2023-08-12 |
human |
| Ramón Cacabelo. Pharmacogenomics and therapeutic prospects in dementia. European archives of psychiatry and clinical neuroscience. vol 258 Suppl 1. 2008-05-06. PMID:18344047. |
mutations in genes directly associated with the amyloid cascade (app, ps1, ps2) are only present in less than 5% of the ad population; however, the presence of the apoe-4 allele in the apolipoprotein e (apoe) gene represents a major risk factor for more than 40% of patients with dementia. |
2008-05-06 |
2023-08-12 |
human |
| Juan Manuel Villalpando-Berumen, Silvia Mejia-Arango, Carlos Alberto Aguilar-Salinas, Maria Luisa Ordonez-Sanchez, Luis Miguel Gutierrez-Robled. Apolipoprotein E epsilon4, Alzheimer's disease, and cognitive performance in elderly Mexican Mestizos. Journal of the American Geriatrics Society. vol 56. issue 4. 2008-04-24. PMID:18205760. |
to determine the relationship between apolipoprotein e (apoe) epsilon4 and alzheimer's disease (ad) in the mexican mestizo population, as well as its effects on the cognitive profile of ad and elderly mestizos without dementia. |
2008-04-24 |
2023-08-12 |
Not clear |
| Ramón Cacabelo. Pharmacogenetic basis for therapeutic optimization in Alzheimer's disease. Molecular diagnosis & therapy. vol 11. issue 6. 2008-04-14. PMID:18078356. |
mutations in genes directly associated with the amyloid cascade (app, psen1, psen2) are present in less than 5% of the alzheimer's disease population; however, the presence of the epsilon4 allele of the apolipoprotein e gene (apoe) represents a major risk factor for more than 40% of patients with dementia. |
2008-04-14 |
2023-08-12 |
human |
| Eleni Hatzifilippou, Tania Banaki, Maria Traka, Ephrosyni Koutsouraki, Vassiliki Costa, Stavros J Baloyanni. Apolipoprotein E phenotype in demented patients in Greek population. The International journal of neuroscience. vol 118. issue 1. 2008-03-25. PMID:18041613. |
the aim of this investigation was to correlate the apoe phenotypes with the type and the severity of dementia in greek demented patients. |
2008-03-25 |
2023-08-12 |
Not clear |