| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlo Lovati, Daniela Galimberti, Diego Albani, Pierluigi Bertora, Eliana Venturelli, Giuliana Cislaghi, Ilaria Guidi, Chiara Fenoglio, Francesca Cortini, Francesca Clerici, Dario Finazzi, Gianluigi Forloni, Elio Scarpini, Claudio Marian. APOE ε2 and ε4 influence the susceptibility for Alzheimer's disease but not other dementias. International journal of molecular epidemiology and genetics. vol 1. issue 3. 2011-07-14. PMID:21537391. |
apolipoprotein e (apoe) genotype was determined in a population of patients with dementia, including 735 patients with alzheimer's disease (ad), 75 with frontotemporal lobar degeneration (ftld), 97 with vascular dementia (vad) and 40 with lewy body dementia (lbd), as well as in 506 age- and gender-matched controls (con). |
2011-07-14 |
2023-08-12 |
Not clear |
| J A R Nicoll, G M Savva, J Stewart, F E Matthews, C Brayne, P Inc. Association between APOE genotype, neuropathology and dementia in the older population of England and Wales. Neuropathology and applied neurobiology. vol 37. issue 3. 2011-06-20. PMID:20880354. |
association between apoe genotype, neuropathology and dementia in the older population of england and wales. |
2011-06-20 |
2023-08-12 |
Not clear |
| J A R Nicoll, G M Savva, J Stewart, F E Matthews, C Brayne, P Inc. Association between APOE genotype, neuropathology and dementia in the older population of England and Wales. Neuropathology and applied neurobiology. vol 37. issue 3. 2011-06-20. PMID:20880354. |
dementia and ad pathology, so it is unclear to which of these variables apoe genotype is more strongly related. |
2011-06-20 |
2023-08-12 |
Not clear |
| Beatriz Marcheco Teruel, Juan J Llibre Rodríguez, Paul McKeigue, Teresa Collazo Mesa T, Evelyn Fuentes, Adolfo Valhuerdi Cepero A, Milagros A Guerra Hernandez, John R M Copeland J R M, Cleusa P Ferri, Martin J Princ. Interactions between genetic admixture, ethnic identity, APOE genotype and dementia prevalence in an admixed Cuban sample; a cross-sectional population survey and nested case-control study. BMC medical genetics. vol 12. 2011-06-17. PMID:21435264. |
interactions between genetic admixture, ethnic identity, apoe genotype and dementia prevalence in an admixed cuban sample; a cross-sectional population survey and nested case-control study. |
2011-06-17 |
2023-08-12 |
Not clear |
| Beatriz Marcheco Teruel, Juan J Llibre Rodríguez, Paul McKeigue, Teresa Collazo Mesa T, Evelyn Fuentes, Adolfo Valhuerdi Cepero A, Milagros A Guerra Hernandez, John R M Copeland J R M, Cleusa P Ferri, Martin J Princ. Interactions between genetic admixture, ethnic identity, APOE genotype and dementia prevalence in an admixed Cuban sample; a cross-sectional population survey and nested case-control study. BMC medical genetics. vol 12. 2011-06-17. PMID:21435264. |
in an admixed population of older cubans we explored the effects of ethnic identity and genetic admixture on apoe genotype, its association with dementia, and dementia prevalence. |
2011-06-17 |
2023-08-12 |
Not clear |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
the effect of mapt h1 and apoe ε4 on transition from mild cognitive impairment to dementia. |
2011-05-25 |
2023-08-12 |
human |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
we prospectively followed three longitudinal independent samples (total n=319) with amnestic mild cognitive impairment (mci) and analyzed whether mapt h1/h2 haplotypes and apoe ε4 polymorphisms accelerated the rate of progression from mci to dementia. |
2011-05-25 |
2023-08-12 |
human |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
apoe ε4 and mapt h1/h1 were independently associated with an increased rate of progression to dementia in the combined sample. |
2011-05-25 |
2023-08-12 |
human |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
apoe ε4 allele also accelerated progression to dementia (hazard ratio=1.47; 95% ci= 1.06-2.04; p=0.020) and reduced the time-to-progression by 0.87 years. |
2011-05-25 |
2023-08-12 |
human |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
additionally, mapt h1/h1 genotype and apoe ε4 allele had an additive effect in progression to dementia, increasing progression rate to dementia (hazard ratio=2.24, 95% ci =1.40-3.58; p=0.001) and shortening time-to-progression to dementia by 2.92 years. |
2011-05-25 |
2023-08-12 |
human |
| Lluís Samaranch, Sebastián Cervantes, Ana Barabash, Alvaro Alonso, José Antonio Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez-Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez-Isla, Pau Pasto. The effect of MAPT H1 and APOE ε4 on transition from mild cognitive impairment to dementia. Journal of Alzheimer's disease : JAD. vol 22. issue 4. 2011-05-25. PMID:20930301. |
our results suggest that both mapt h1/h1 genotype and apoe ε4 allele lead to a more rapid progression to dementia among mci subjects, probably mediating an increased rate of amyloid-β and tau brain deposition. |
2011-05-25 |
2023-08-12 |
human |
| Dan Mungas, Laurel Beckett, Danielle Harvey, Sarah Tomaszewski Farias, Bruce Reed, Owen Carmichael, John Olichney, Joshua Miller, Charles DeCarl. Heterogeneity of cognitive trajectories in diverse older persons. Psychology and aging. vol 25. issue 3. 2011-05-09. PMID:20677882. |
global status, measured by the clinical dementia rating scale (morris, 1993), predicted change in semantic memory and executive function, whereas apoe genotype predicted change in verbal episodic memory, and age had no effect on rates of change in any domain independent of global status and apoe. |
2011-05-09 |
2023-08-12 |
Not clear |
| Srikala Bharath, Meera Purushottam, Odity Mukherjee, Bhavani Shankara Bagepally, Om Prakash, Lakshminarayanan Kota, Srinivas Brahmadevarahalli Krishnappa, Palanimuthu Thangaraju Sivakumar, Sanjeev Jain, Mathew Varghes. Apolipoprotein E polymorphism and dementia: a hospital-based study from southern India. Dementia and geriatric cognitive disorders. vol 30. issue 6. 2011-04-25. PMID:21252538. |
to evaluate the apoe gene polymorphism among patients with dementia from southern india. |
2011-04-25 |
2023-08-12 |
Not clear |
| Nasim Mansoori, Manjari Tripathi, Rizwan Alam, Kalpana Luthra, Lakshmy Ramakrishnan, Shama Parveen, Asok K Mukhopadhya. IL-6-174 G/C and ApoE gene polymorphisms in Alzheimer's and vascular dementia patients attending the cognitive disorder clinic of the All India Institute of Medical Sciences, New Delhi. Dementia and geriatric cognitive disorders. vol 30. issue 6. 2011-04-25. PMID:21252539. |
il-6-174 g/c and apoe gene polymorphisms in alzheimer's and vascular dementia patients attending the cognitive disorder clinic of the all india institute of medical sciences, new delhi. |
2011-04-25 |
2023-08-12 |
Not clear |
| Masatoshi Takeda, Rocío Martínez, Takashi Kudo, Toshihisa Tanaka, Masayasu Okochi, Shinji Tagami, Takashi Morihara, Ryota Hashimoto, Ramón Cacabelo. Apolipoprotein E and central nervous system disorders: reviews of clinical findings. Psychiatry and clinical neurosciences. vol 64. issue 6. 2011-04-07. PMID:21105952. |
the pathogenic role of apoe-4 is still to be clarified; however, diverse evidence suggests that apoe may play pleiotropic functions in dementia and central nervous system disorders. |
2011-04-07 |
2023-08-12 |
Not clear |
| Valérie Leduc, Stéphanie Jasmin-Bélanger, Judes Poirie. APOE and cholesterol homeostasis in Alzheimer's disease. Trends in molecular medicine. vol 16. issue 10. 2011-03-17. PMID:20817608. |
these associations include the recognition of cholesterol transporters apolipoprotein e (apoe), apoc1 and apoj as major genetic risk factors for common ad and observations associating risk factors for cardiovascular disease such as high midlife plasma cholesterol, diabetes, stroke, obesity and hypertension to dementia. |
2011-03-17 |
2023-08-12 |
Not clear |
| Dina Zekry, François R Herrmann, Irmgard Irminger-Finger, Cristophe Graf, Chantal Genet, Anna-Maria Vitale, Jean-Pierre Michel, Gabriel Gold, Karl-Heinz Kraus. Telomere length and ApoE polymorphism in mild cognitive impairment, degenerative and vascular dementia. Journal of the neurological sciences. vol 299. issue 1-2. 2011-03-16. PMID:20709332. |
telomere length and apoe polymorphism in mild cognitive impairment, degenerative and vascular dementia. |
2011-03-16 |
2023-08-12 |
Not clear |
| John A Joska, Marc Combrinck, Victor G Valcour, Jacqueline Hoare, Felicity Leisegang, Anna Cecilia Mahne, Landon Myer, Dan J Stei. Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South Africa. Journal of neurovirology. vol 16. issue 5. 2011-02-07. PMID:20825268. |
it is not known whether the apolipoprotein e (apoe) ?4 allelic variant is associated with human immunodeficiency virus (hiv)-associated dementia (had) in a south african population, where hiv clade c is predominant. |
2011-02-07 |
2023-08-12 |
human |
| M Rusanen, S Rovio, T Ngandu, A Nissinen, J Tuomilehto, H Soininen, M Kivipelt. Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: a population-based cardiovascular risk factors, aging and dementia study. Dementia and geriatric cognitive disorders. vol 30. issue 3. 2011-01-21. PMID:20847559. |
to elucidate the effect of midlife smoking on the risk of dementia and alzheimer's disease (ad), and the possible modification of this relation by the apolipoprotein e (apoe) ε4. |
2011-01-21 |
2023-08-12 |
Not clear |
| V P Prasher, S G Sajith, P Mehta, W B Zigman, N Schup. Plasma beta-amyloid and duration of Alzheimer's disease in adults with Down syndrome. International journal of geriatric psychiatry. vol 25. issue 2. 2011-01-19. PMID:19513990. |
to investigate the relation of plasma levels of abeta peptides (abeta1-40 and abeta1-42) and apolipoprotein e (apoe) genotype to dementia status, and the duration of alzheimer's disease (ad) in adults with down syndrome (ds). |
2011-01-19 |
2023-08-12 |
Not clear |