Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xiaoxia Li, Yuan Gao, Baoying Li, Wenqian Zhao, Qian Cai, Wenbin Yin, Shudong Zeng, Xiaoli Li, Haiqing Gao, Mei Chen. Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice. Frontiers in molecular neuroscience. vol 16. 2023-12-01. PMID:38025258. |
we aimed to explore the mechanism of hippocampal damage during diabetes and evaluate the potential role of d-pinitol (dp) in protecting hippocampal tissue and improving cognitive dysfunction. |
2023-12-01 |
2023-12-07 |
mouse |
Xiaoxia Li, Yuan Gao, Baoying Li, Wenqian Zhao, Qian Cai, Wenbin Yin, Shudong Zeng, Xiaoli Li, Haiqing Gao, Mei Chen. Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice. Frontiers in molecular neuroscience. vol 16. 2023-12-01. PMID:38025258. |
we aimed to explore the mechanism of hippocampal damage during diabetes and evaluate the potential role of d-pinitol (dp) in protecting hippocampal tissue and improving cognitive dysfunction. |
2023-11-29 |
2023-12-07 |
mouse |
Caio Yogi Yonamine, Maria Luiza Estimo Michalani, Rafael Junges Moreira, Ubiratan Fabres Machad. Glucose Transport and Utilization in the Hippocampus: From Neurophysiology to Diabetes-Related Development of Dementia. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003671. |
finally, we discuss how these abnormalities are accompained by the reduction in the expression and translocation of the high capacity insulin-sensitive glucose transporter glut4 in hippocampal neurons, which leads to neurocytoglycopenia and eventually to cognitive dysfunction. |
2023-11-25 |
2023-11-28 |
Not clear |
Qinghai Meng, Ying Chao, Shurui Zhang, Xue Ding, Han Feng, Chenyan Zhang, Bowen Liu, Weijie Zhu, Yu Li, Qichun Zhang, Huangjin Tong, Lixing Wu, Huimin Bia. Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment. Molecular brain. vol 16. issue 1. 2023-11-24. PMID:37986006. |
in the present study, we analyzed sequencing data from female hippocampus and normal breast aspirate samples from normal and alzheimer's disease (ad) women, and the results suggest that abnormal ers signaling is associated with dyslipidemia and cognitive dysfunction. |
2023-11-24 |
2023-11-28 |
mouse |
Yinli Shi, Pei Sheng, Yun Zhao, Xu Wang, Xiru Xu, Sifan Su. Based on Bioinformatics to Explore the Mechanism of "Tangzhiqing" Decoction Alleviating Type 2 Diabetes-associated Cognitive Dysfunction in Mice by Regulating Hippocampal Neuron Apoptosis and Autophagy. Combinatorial chemistry & high throughput screening. 2023-11-22. PMID:37990900. |
based on bioinformatics to explore the mechanism of "tangzhiqing" decoction alleviating type 2 diabetes-associated cognitive dysfunction in mice by regulating hippocampal neuron apoptosis and autophagy. |
2023-11-22 |
2023-11-29 |
mouse |
Alexandra V Ulyanova, Christopher D Adam, Carlo Cottone, Nikhil Maheshwari, Michael R Grovola, Oceane E Fruchet, Jami Alamar, Paul F Koch, Victoria E Johnson, D Kacy Cullen, John A Wol. Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion. Communications biology. vol 6. issue 1. 2023-11-09. PMID:37945934. |
these data demonstrate that a single concussion can lead to significant neuronal and circuit level changes in the hippocampus, which may contribute to cognitive dysfunction following mtbi. |
2023-11-09 |
2023-11-20 |
Not clear |
Yansong Li, Tao Jiang, Mengyu Du, Shuxuan He, Ning Huang, Bo Cheng, Chaoying Yan, Wenxin Tang, Wei Gao, Hongyan Guo, Qiao Li, Qiang Wan. Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction. Experimental & molecular medicine. 2023-11-01. PMID:37907746. |
here, we performed a comprehensive study on leptin receptor-deficient t2dm mice and their littermate m/m mice and revealed that 24-week-old db/db mice had cognitive dysfunction and excessive endogenous fructose metabolism in the hippocampus by multiomics analysis and further experimental validation. |
2023-11-01 |
2023-11-08 |
mouse |
Qiong Xiang, Jia-Sheng Tao, Shuai Dong, Xiao-Lin Liu, Liang Yang, Li-Ni Liu, Jing Deng, Xian-Hui L. Heterogeneity and synaptic plasticity analysis of hippocampus based on db Psychoneuroendocrinology. vol 159. 2023-10-28. PMID:37898037. |
heterogeneity and synaptic plasticity analysis of hippocampus based on db chronic hyperglycemia can cause changes in synaptic plasticity of hippocampal cells, which has accelerated the pathological process of cognitive dysfunction. |
2023-10-28 |
2023-11-08 |
Not clear |
Lan Fu, Lin-Na Guan, Hongye Zu. Long period changes of hippocampal diffusion kurtosis imaging and its correlation with cognitive dysfunction after incomplete cerebral ischemia-reperfusion in rats. Experimental brain research. 2023-10-25. PMID:37878109. |
long period changes of hippocampal diffusion kurtosis imaging and its correlation with cognitive dysfunction after incomplete cerebral ischemia-reperfusion in rats. |
2023-10-25 |
2023-11-08 |
rat |
Georgios Alkis Zisiadis, Androniki Alevyzaki, Elene Nicola, Carlos F D Rodrigues, Klas Blomgren, Ahmed M Osma. Memantine increases the dendritic complexity of hippocampal young neurons in the juvenile brain after cranial irradiation. Frontiers in oncology. vol 13. 2023-10-20. PMID:37860190. |
cranial irradiation (ir) negatively regulates hippocampal neurogenesis and causes cognitive dysfunctions in cancer survivors, especially in pediatric patients. |
2023-10-20 |
2023-11-08 |
mouse |
R M Aljarar. Neuroprotective effects of a combination of Boswellia papyrifera and Syzygium aromaticum on AlCl3 induced Alzheimer's disease in male albino rat. Brazilian journal of biology = Revista brasleira de biologia. vol 83. 2023-10-20. PMID:37851769. |
alzheimer's disease (ad) is the most common neurodegenerative disease characterized by hippocampal, and cortical neuron deterioration, oxidative stress, and severe cognitive dysfunction. |
2023-10-20 |
2023-11-08 |
rat |
Zhanhong Liu, Kaina Xu, Shichao Pan, Na Zhang, Dapeng Wang, Ying Chen, Yaru Zhao, Siqi Wang, Jing Li, Xu Ton. Manganese-enhanced magnetic resonance assessment of changes in hippocampal neural function after the treatment of radiation-induced brain injury with bone marrow mesenchymal stem cells. Brain research bulletin. 2023-10-20. PMID:37863438. |
after bmscs treatment of ribi, cognitive dysfunction improved significantly, the expression of hippocampal neurofunctional proteins was increased, the integrity of the hippocampal neural structure was protected, and nerve cell survival was enhanced. |
2023-10-20 |
2023-11-08 |
rat |
Meng Meng Shi, Xiao Fan Xu, Qiu Min Sun, Mingying Luo, Dan Dan Liu, Dong Min Guo, Ling Chen, Xiao Lin Zhong, Yang Xu, Wen Yu Ca. Betaine prevents cognitive dysfunction by suppressing hippocampal microglial activation in chronic social isolated male mice. Phytotherapy research : PTR. vol 37. issue 10. 2023-10-17. PMID:37846157. |
betaine prevents cognitive dysfunction by suppressing hippocampal microglial activation in chronic social isolated male mice. |
2023-10-17 |
2023-11-08 |
mouse |
S Y Ho, L T Shieh, C C Huang, C P Chan. Hyperbaric Oxygen Therapy Attenuates the Whole Brain Radiotherapy-Induced Progressive Cognitive Dysfunction via Promoting Hippocampal Neurogenesis in Rats. International journal of radiation oncology, biology, physics. vol 117. issue 2S. 2023-10-03. PMID:37784936. |
hyperbaric oxygen therapy attenuates the whole brain radiotherapy-induced progressive cognitive dysfunction via promoting hippocampal neurogenesis in rats. |
2023-10-03 |
2023-10-07 |
rat |
Susana Bulnes, Marina Picó-Gallardo, Harkaitz Bengoetxea, José Vicente Lafuent. Effects of curcumin nanodelivery on schizophrenia and glioblastoma. International review of neurobiology. vol 171. 2023-10-02. PMID:37783555. |
schizophrenia is a disabling psychiatric disorder related with an aberrant functional coupling between hippocampus and prefrontal cortex that might be crucial for cognitive dysfunction. |
2023-10-02 |
2023-10-07 |
Not clear |
Burak Yulug, Behçet Ayyıldız, Sevilay Ayyıldız, Dila Sayman, Ali Behram Salar, Seyda Cankaya, Ece Ozdemir, Ahmet Ozsimsek, Cagla Ceren Kurt, Hatice Lakadamyalı, Aynur Akturk, Özlem Altay, Lutfu Hanoglu, Halil Aziz Velioglu, Adil Mardinogl. Infection with COVID-19 is no longer a public emergency: But what about degenerative dementia? Journal of medical virology. vol 95. issue 9. 2023-09-19. PMID:37724347. |
our findings of higher hippocampal connectivity with no observable hippocampal morphological changes even in mild covid cases may be represent evidence of a prestructural compensatory mechanism for stimulating additional neuronal resources to combat cognitive dysfunction as recently shown for the prodromal stages of degenerative cognitive disorders. |
2023-09-19 |
2023-10-07 |
Not clear |
Jie Li, Wen Jiang, Yuefang Cai, Zhenqiu Ning, Yingying Zhou, Chengyi Wang, Sookja Ki Chung, Yan Huang, Jingbo Sun, Minzhen Deng, Lihua Zhou, Xiao Chen. Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism. Neural regeneration research. vol 19. issue 3. 2023-09-18. PMID:37721297. |
overall, this study demonstrates that astrocytic endothelin-1 overexpression can impair hippocampal neurogenesis and that it is correlated with lipid metabolism in poststroke cognitive dysfunction. |
2023-09-18 |
2023-10-07 |
mouse |
Yuelian Luo, Jiayi Liu, Yu Hong, Shuling Peng, Shiyu Men. Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice. Behavioural brain research. 2023-09-16. PMID:37716552. |
sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice. |
2023-09-16 |
2023-10-07 |
mouse |
Yuelian Luo, Jiayi Liu, Yu Hong, Shuling Peng, Shiyu Men. Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice. Behavioural brain research. 2023-09-16. PMID:37716552. |
these findings suggest that sevoflurane-induced hypotension may lead to the cognitive dysfunction and hippocampal inflammation. |
2023-09-16 |
2023-10-07 |
mouse |
Taylor O Phillips, Madelyn Castro, Rishi K Vas, Lorena A Ferguson, Amritha Harikumar, Stephanie L Lea. Perceived antidepressant efficacy associated with reduced negative and enhanced neutral mnemonic discrimination. Frontiers in human neuroscience. vol 17. 2023-09-13. PMID:37701502. |
mnemonic discrimination tasks have been designed to tax hippocampal pattern separation in humans and provide a powerful approach to develop a mechanistic account for cognitive dysfunction in depression. |
2023-09-13 |
2023-10-07 |
Not clear |