| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cornelia Soff, Anna Sotnikova, Hanna Christiansen, Katja Becker, Michael Siniatchki. Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 1. 2018-02-27. PMID:27853926. |
to test this hypothesis, fifteen adolescents with adhd (12-16 years old, three girls and 12 boys) were treated according to the randomized, double-blinded, sham-controlled, crossover design with either 1 ma anodal tdcs over the left dorsolateral prefrontal cortex or with the sham protocol 5 days each with a 2 weeks pause between these conditions. |
2018-02-27 |
2023-08-13 |
Not clear |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
to investigate the key regulators in the prefrontal cortex (pfc), the major affected areas of adhd, microrna (mir)-138,138*, 34c*, 296, and 494, were noted for their significant downregulation in adhd model rats spontaneously hypertensive rats (shrs) compared to wistar kyoto (wky) rat control. |
2018-02-13 |
2023-08-13 |
rat |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
in the pfc of adhd model rats shr, nr3c1 expression was abnormally elevated and reversely correlated with the levels of mir-138-1, 34c, 296, and 494 expression. |
2018-02-13 |
2023-08-13 |
rat |
| Li Hui Wu, Wei Cheng, Mei Yu, Bao Mei He, Hui Sun, Qi Chen, Yi Wei Dong, Xiao Ting Shao, Qian Qian Cai, Min Peng, Xing Zhong W. Nr3C1-Bhlhb2 Axis Dysregulation Is Involved in the Development of Attention Deficit Hyperactivity. Molecular neurobiology. vol 54. issue 2. 2018-02-13. PMID:26820676. |
consistently, bhlhb2 expression was significantly higher in pfc of adhd model shr than control. |
2018-02-13 |
2023-08-13 |
rat |
| I J I Dela Peña, I Dela Peña, J B de la Peña, H J Kim, A Sohn, C Y Shin, D H Han, B-N Kim, J H Ryu, J H Cheon. Transcriptional profiling of SHR/NCrl prefrontal cortex shows hyperactivity-associated genes responsive to amphetamine challenge. Genes, brain, and behavior. vol 16. issue 7. 2017-12-22. PMID:28422445. |
to this end, we examined differentially expressed genes (degs) in the prefrontal cortex (pfc) of shr/ncrl, an animal model of adhd, compared with its genetic control, the wistar kyoto (wky/ncrl) rat and the wistar rat, strain used to represent the 'normal' heterogeneous population. |
2017-12-22 |
2023-08-13 |
rat |
| Igor Dórea Bandeira, Rachel Silvany Quadros Guimarães, João Gabriel Jagersbacher, Thiago Lima Barretto, Jéssica Regina de Jesus-Silva, Samantha Nunes Santos, Nayara Argollo, Rita Lucen. Transcranial Direct Current Stimulation in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD): A Pilot Study. Journal of child neurology. vol 31. issue 7. 2017-12-20. PMID:26879095. |
studies investigating the possible benefits of transcranial direct current stimulation on left dorsolateral prefrontal cortex in children and adolescents with attention-deficit hyperactivity disorder (adhd) have not been performed. |
2017-12-20 |
2023-08-13 |
human |
| Andrea E Spencer, Marie-France Marin, Mohammed R Milad, Thomas J Spencer, Olivia E Bogucki, Amanda L Pope, Natalie Plasencia, Brittany Hughes, Edward F Pace-Schott, Maura Fitzgerald, Mai Uchida, Joseph Biederma. Abnormal fear circuitry in Attention Deficit Hyperactivity Disorder: A controlled magnetic resonance imaging study. Psychiatry research. Neuroimaging. vol 262. 2017-11-16. PMID:28235692. |
compared to healthy controls, adhd subjects had significantly greater insular cortex activation during early extinction, lesser dorsal anterior cingulate cortex (dacc) activation during late extinction, lesser ventromedial prefrontal cortex (vmpfc) activation during late extinction learning and extinction recall, and greater hippocampal activation during extinction recall. |
2017-11-16 |
2023-08-13 |
human |
| Lydia Oikonomidis, Andrea M Santangelo, Yoshiro Shiba, F Hannah Clarke, Trevor W Robbins, Angela C Robert. A dimensional approach to modeling symptoms of neuropsychiatric disorders in the marmoset monkey. Developmental neurobiology. vol 77. issue 3. 2017-10-13. PMID:27589556. |
many of the disorders involve dysfunction within the prefrontal cortex (pfc) and so the marmoset, due to their highly developed pfc and small size, is an ideal species for studying the neurobiological basis of the behavioural dimensions that underlie these symptoms.here we focus on a battery of tests that address dysfunction spanning the cognitive (cognitive inflexibility and working memory), negative valence (fear generalisation and negative bias) and positive valence (anhedonia) systems pertinent for understanding disorders such as adhd, schizophrenia, anxiety, depression and ocd. |
2017-10-13 |
2023-08-13 |
monkey |
| Sofiya Hupalo, Craig W Berridg. Working Memory Impairing Actions of Corticotropin-Releasing Factor (CRF) Neurotransmission in the Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 11. 2017-08-31. PMID:27272767. |
pfc cognitive dysfunction is implicated in multiple psychopathologies, including attention deficit hyperactivity disorder (adhd). |
2017-08-31 |
2023-08-13 |
rat |
| G A Ünal, A N İnci Kenar, E Tepeli, Y Kıroğlu, H Herke. Relationship between the SNAP-25 gene and the effects of methylphenidate on the anterior cingulate cortex of patients with adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 20. issue 11. 2017-08-22. PMID:27338073. |
thus, the present study aimed to determine the relationship between changes in creatine (cr), choline (cho), and n-acetyl aspartate (naa) levels in the prefrontal cortex (pfc) and anterior cingulate cortex (acc) of adults with adhd and the snap-25 gene polymorphism following the use of mph. |
2017-08-22 |
2023-08-13 |
Not clear |
| Tohru Kodama, Takashi Kojima, Yoshiko Honda, Takayuki Hosokawa, Ken-Ichiro Tsutsui, Masataka Watanab. Oral Administration of Methylphenidate (Ritalin) Affects Dopamine Release Differentially Between the Prefrontal Cortex and Striatum: A Microdialysis Study in the Monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 9. 2017-08-18. PMID:28154152. |
however, adhd patients show impaired prefrontal cortex (pfc) function and mph administration is associated with increased neural activity in the pfc. |
2017-08-18 |
2023-08-13 |
human |
| A N Inci Kenar, G A Unal, Y Kiroglu, H Herke. Effects of methylphenidate treatment on the cerebellum in adult attention-deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 21. issue 2. 2017-07-24. PMID:28165547. |
this study investigated the relationship between the use of methylphenidate (mph) and changes in creatine, choline, and n-acetyl-aspartate (naa) in the dorsolateral prefrontal cortex (dlpfc), striatum, cerebellum, and anterior cingulate cortex (acc) in adults with attention-deficit hyperactivity disorder (adhd). |
2017-07-24 |
2023-08-13 |
Not clear |
| Ike Dela Peña, Wei-Xing Sh. Chemogenetic approach to model hypofrontality. Medical hypotheses. vol 93. 2017-06-15. PMID:27372868. |
clinical evidence suggests that the prefrontal cortex (pfc) is hypofunctional in disorders including schizophrenia, drug addiction, and attention-deficit/hyperactivity disorder (adhd). |
2017-06-15 |
2023-08-13 |
Not clear |
| Huey-Ling Chiang, Yu-Jen Chen, Yu-Chun Lo, Wen-Yih I Tseng, Susan S Ga. Altered white matter tract property related to impaired focused attention, sustained attention, cognitive impulsivity and vigilance in attention-deficit/ hyperactivity disorder. Journal of psychiatry & neuroscience : JPN. vol 40. issue 5. 2016-12-13. PMID:25871496. |
we sought to compare the microstructural property of fibre tracts associated with the prefrontal cortex and its association with adhd symptoms and a wide range of attention performance in youth with adhd and healthy controls. |
2016-12-13 |
2023-08-13 |
Not clear |
| J Jin, L Liu, Q Gao, R C K Chan, H Li, Y Chen, Y Wang, Q Qia. The divergent impact of COMT Val158Met on executive function in children with and without attention-deficit/hyperactivity disorder. Genes, brain, and behavior. vol 15. issue 2. 2016-12-13. PMID:26560848. |
children with attention-deficit/hyperactivity disorder (adhd) usually display deficits in executive function (ef), which are primarily mediated by prefrontal cortex (pfc). |
2016-12-13 |
2023-08-13 |
Not clear |
| A N Inci Kenar, G A Ünal, H Güler, B Albuz, Y Kıroğlu, M E Erdal, H Herke. Relationship between the DAT1 gene and the effects of methylphenidate administration in adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study. European review for medical and pharmacological sciences. vol 20. issue 7. 2016-12-13. PMID:27097961. |
this study investigated the relationship between dat1 gene polymorphisms and the effects of methylphenidate (mph) administration on n-acetyl aspartate (naa), creatine (cr), and choline (cho) levels in the anterior cingulate cortex, prefrontal cortex, striatum, and cerebellum in adult patients with attention deficit hyperactivity disorder (adhd). |
2016-12-13 |
2023-08-13 |
Not clear |
| Nick Ortiz, Aisling Parsons, Robert Whelan, Katie Brennan, Maria L F Agan, Redmond O'Connell, Jessica Bramham, Hugh Garava. Decreased frontal, striatal and cerebellar activation in adults with ADHD during an adaptive delay discounting task. Acta neurobiologiae experimentalis. vol 75. issue 3. 2016-11-08. PMID:26581388. |
however, adults with adhd showed less task activation in a number of regions including the dorsolateral prefrontal cortex, superior frontal gyrus, anterior cingulate, caudate nucleus and declive of the cerebellum. |
2016-11-08 |
2023-08-13 |
human |
| Hsiang-Yuan Lin, Wen-Yih Isaac Tseng, Meng-Chuan Lai, Kayako Matsuo, Susan Shur-Fen Ga. Altered resting-state frontoparietal control network in children with attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society : JINS. vol 21. issue 4. 2016-11-01. PMID:25928822. |
involvement of the frontoparietal control network based on the anterior prefrontal cortex in neurobiological mechanisms of adhd has yet to be tested. |
2016-11-01 |
2023-08-13 |
human |
| Hsiang-Yuan Lin, Wen-Yih Isaac Tseng, Meng-Chuan Lai, Kayako Matsuo, Susan Shur-Fen Ga. Altered resting-state frontoparietal control network in children with attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society : JINS. vol 21. issue 4. 2016-11-01. PMID:25928822. |
compared with td children, children with adhd demonstrated weaker connectivity between the right anterior prefrontal cortex (pfc) and the right ventrolateral pfc, and between the left anterior pfc and the right inferior parietal lobule. |
2016-11-01 |
2023-08-13 |
human |
| Daniel W Bryden, Amanda C Burton, Brian R Barnett, Valerie J Cohen, Taylor N Hearn, Emily A Jones, Reshma J Kariyil, Alice Kunin, Sae In Kwak, Jessica Lee, Brooke L Lubinski, Gautam K Rao, Ashley Zhan, Matthew R Roesc. Prenatal Nicotine Exposure Impairs Executive Control Signals in Medial Prefrontal Cortex. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 3. 2016-10-06. PMID:26189451. |
current literature suggests that core deficits observed in adhd reflect abnormal inhibitory control governed by the prefrontal cortex. |
2016-10-06 |
2023-08-13 |
rat |