| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Takamatsu, Y Hagino, A Sato, T Takahashi, S Y Nagasawa, Y Kubo, M Mizuguchi, G R Uhl, I Sora, K Iked. Improvement of learning and increase in dopamine level in the frontal cortex by methylphenidate in mice lacking dopamine transporter. Current molecular medicine. vol 15. issue 3. 2016-02-12. PMID:25817856. |
interestingly, the effective dose of mph increased extracellular dopamine in the prefrontal cortex but not striatum, suggesting an important role for changes in prefrontal dopamine in adhd. |
2016-02-12 |
2023-08-13 |
mouse |
| Tianqi Wu, Chunxiao Chen, Lei Yang, Min Zhang, Xin Zhang, Jia Jia, Jing Wang, Ziyi Fu, Xianwei Cui, Chenbo Ji, Xirong Guo, Meiling Tong, Ronghua Chen, Qin Hong, Xia Ch. Distinct lncRNA expression profiles in the prefrontal cortex of SD rats after exposure to methylphenidate. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 70. 2016-01-04. PMID:25776507. |
our study showed distinct expression profiles of lncrnas in the normal rat prefrontal cortex after exposure to mph, offering information for further research of mph and may suggesting a new therapeutic target for adhd. |
2016-01-04 |
2023-08-13 |
rat |
| Nicholas A Donnelly, Tahl Holtzman, P Dylan Rich, Alejo J Nevado-Holgado, Anushka B P Fernando, Gert Van Dijck, Tobias Holzhammer, Oliver Paul, Patrick Ruther, Ole Paulsen, Trevor W Robbins, Jeffrey W Dalle. Oscillatory activity in the medial prefrontal cortex and nucleus accumbens correlates with impulsivity and reward outcome. PloS one. vol 9. issue 10. 2015-12-17. PMID:25333512. |
such behaviour is governed by a network of brain regions including the prefrontal cortex (pfc) and nucleus accumbens (nacb) and is prevalent in disorders including attention deficit hyperactivity disorder (adhd) and drug addiction. |
2015-12-17 |
2023-08-13 |
rat |
| L A Ruocco, C Treno, U A Gironi Carnevale, C Arra, G Boatto, C Pagano, A Tino, M Nieddu, M Michel, I Prikulis, E Carboni, M A de Souza Silva, J P Huston, A G Sadile, C Kort. Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum. Amino acids. vol 47. issue 3. 2015-10-26. PMID:25595600. |
immunization with disc1 protein in an animal model of adhd influences behavior and excitatory amino acids in prefrontal cortex and striatum. |
2015-10-26 |
2023-08-13 |
rat |
| Ken Eagl. ADHD impacted by sulfotransferase (SULT1A) inhibition from artificial food colors and plant-based foods. Physiology & behavior. vol 135. 2015-10-07. PMID:24952261. |
recent work has shown human in vivo sult1a inhibition leading to incremental catecholamines, and an inverted-u relationship between brain catecholamines and proper functioning of the prefrontal cortex where adhd behavior can arise. |
2015-10-07 |
2023-08-13 |
human |
| L A Ruocco, C Treno, U A Gironi Carnevale, C Arra, C Mattern, J P Huston, M A de Souza Silva, S Nikolaus, A Scorziello, M Nieddu, G Boatto, P Illiano, C Pagano, A Tino, A G Sadil. Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum. Amino acids. vol 46. issue 9. 2015-08-28. PMID:24862315. |
prepuberal intranasal dopamine treatment in an animal model of adhd ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum. |
2015-08-28 |
2023-08-13 |
rat |
| Carlos Gómez, Jesús Poza, Alberto Fernández, Alejandro Bachiller, Javier Gómez, Roberto Horner. Entropy analysis of MEG background activity in attention-deficit/hyperactivity disorder. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2013. 2015-08-07. PMID:24110872. |
our results support the hypothesis that adhd is characterized by a delay of cortical maturation in the prefrontal cortex. |
2015-08-07 |
2023-08-12 |
Not clear |
| Jose Martinez-Raga, Carlos Knecht, Raquel de Alvar. Profile of guanfacine extended release and its potential in the treatment of attention-deficit hyperactivity disorder. Neuropsychiatric disease and treatment. vol 11. 2015-06-11. PMID:26064054. |
though the precise mechanism of action of guanfacine in the treatment of adhd is not fully understood, it is thought to act directly by enhancing noradrenaline functioning via α2a-adrenoceptors in the prefrontal cortex. |
2015-06-11 |
2023-08-13 |
Not clear |
| Sharon Morein-Zamir, Chris Dodds, Tim J van Hartevelt, Wolfgang Schwarzkopf, Barbara Sahakian, Ulrich Müller, Trevor Robbin. Hypoactivation in right inferior frontal cortex is specifically associated with motor response inhibition in adult ADHD. Human brain mapping. vol 35. issue 10. 2015-05-20. PMID:24819224. |
the results are consistent with the notion of a selective neurocognitive deficit in response inhibition in adult adhd associated with abnormal functional activation in the prefrontal cortex, whilst ruling out likely group differences in attentional orienting, arousal and motivation. |
2015-05-20 |
2023-08-13 |
human |
| Ayaka Ishii-Takahashi, Ryu Takizawa, Yukika Nishimura, Yuki Kawakubo, Hitoshi Kuwabara, Junko Matsubayashi, Kasumi Hamada, Shiho Okuhata, Noriaki Yahata, Takashi Igarashi, Shingo Kawasaki, Hidenori Yamasue, Nobumasa Kato, Kiyoto Kasai, Yukiko Kan. Prefrontal activation during inhibitory control measured by near-infrared spectroscopy for differentiating between autism spectrum disorders and attention deficit hyperactivity disorder in adults. NeuroImage. Clinical. vol 4. 2015-05-19. PMID:24298446. |
significant differences were observed in the left ventrolateral prefrontal cortex between the asds and adhd groups during the stop signal task. |
2015-05-19 |
2023-08-12 |
human |
| Thomas Hoegl, Stephan Bender, Johannes Buchmann, Oliver Kratz, Gunther H Moll, Hartmut Heinric. [Transcranial magnetic stimulation (TMS), inhibition processes and attention deficit/hyperactivity disorder (ADHD) - an overview]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 42. issue 6. 2015-03-20. PMID:25335520. |
applying this bimodal approach, strong evidence for a deviant implementation of motor control in children with adhd and probably compensatory mechanisms (with involvement of the prefrontal cortex) was obtained. |
2015-03-20 |
2023-08-13 |
Not clear |
| Erin M Miller, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, Paul E A Glase. Aberrant glutamate signaling in the prefrontal cortex and striatum of the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder. Psychopharmacology. vol 231. issue 15. 2015-03-03. PMID:24682500. |
attention-deficit/hyperactivity disorder (adhd) is thought to involve hypofunctional catecholamine systems in the striatum, nucleus accumbens, and prefrontal cortex (pfc); however, recent clinical evidence has implicated glutamate dysfunction in the pathophysiology of adhd. |
2015-03-03 |
2023-08-12 |
rat |
| Erin M Miller, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, Paul E A Glase. Aberrant glutamate signaling in the prefrontal cortex and striatum of the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder. Psychopharmacology. vol 231. issue 15. 2015-03-03. PMID:24682500. |
the spontaneously hypertensive rat (shr) model of adhd combined type (c) has been found to have a hypofunctional dopamine system in the ventral striatum, nucleus accumbens, and pfc compared to the control wistar kyoto (wky) strain. |
2015-03-03 |
2023-08-12 |
rat |
| Anna-Maria Marx, Ann-Christine Ehlis, Adrian Furdea, Martin Holtmann, Tobias Banaschewski, Daniel Brandeis, Aribert Rothenberger, Holger Gevensleben, Christine M Freitag, Yvonne Fuchsenberger, Andreas J Fallgatter, Ute Streh. Near-infrared spectroscopy (NIRS) neurofeedback as a treatment for children with attention deficit hyperactivity disorder (ADHD)-a pilot study. Frontiers in human neuroscience. vol 8. 2015-01-22. PMID:25610390. |
oxygenated hemoglobin in the prefrontal cortex of children with adhd was measured and fed back. |
2015-01-22 |
2023-08-13 |
mouse |
| Naomi Matsuura, Makoto Ishitobi, Sumiyoshi Arai, Kaori Kawamura, Mizuki Asano, Keisuke Inohara, Tohru Fujioka, Tadamasa Narimoto, Yuji Wada, Michio Hiratani, Hirotaka Kosak. Effects of methylphenidate in children with attention deficit hyperactivity disorder: a near-infrared spectroscopy study with CANTAB®. Child and adolescent psychiatry and mental health. vol 8. issue 1. 2015-01-21. PMID:25606052. |
a wide range of evidence supports the methylphenidate (mph)-induced enhancement of prefrontal cortex (pfc) functioning and improvements in behavioral symptoms in patients with attention deficit hyperactivity disorder (adhd). |
2015-01-21 |
2023-08-13 |
Not clear |
| Gonzalo P Urcelay, Jeffrey W Dalle. Linking ADHD, impulsivity, and drug abuse: a neuropsychological perspective. Current topics in behavioral neurosciences. vol 9. 2015-01-20. PMID:21365439. |
the case for executive dysfunction in adhd and drug addiction is critically reviewed in the context of dissociable cognitive control processes mediated by the dorsolateral prefrontal cortex (dlpfc), the orbital and ventral medial prefrontal cortex (vmpfc). |
2015-01-20 |
2023-08-12 |
Not clear |
| Jamie M Gauthier, David H Tassin, Linda P Dwoskin, Kathleen M Kanta. Effects of dopamine D1 receptor blockade in the prelimbic prefrontal cortex or lateral dorsal striatum on frontostriatal function in Wistar and Spontaneously Hypertensive Rats. Behavioural brain research. vol 268. 2014-12-16. PMID:24755309. |
spontaneously hypertensive rats (shr), a heuristically useful animal model of adhd, were evaluated against normotensive wistar (wis) controls to determine whether dopamine d1 receptor blockade of either prelimbic prefrontal cortex (plpfc) or lateral dorsal striatum (ldst) altered learning functions of both interconnected sites. |
2014-12-16 |
2023-08-13 |
rat |
| Alberto Fernández-Jaén, Sara López-Martín, Jacobo Albert, Daniel Martín Fernández-Mayoralas, Ana Laura Fernández-Perrone, Diana Quiñones Tapia, Beatriz Calleja-Pére. Cortical thinning of temporal pole and orbitofrontal cortex in medication-naïve children and adolescents with ADHD. Psychiatry research. vol 224. issue 1. 2014-12-05. PMID:25085707. |
structural and functional brain studies on attention deficit/hyperactivity disorder (adhd) have primarily examined anatomical abnormalities in the prefronto-striatal circuitry (especially, dorsal and lateral areas of the prefrontal cortex and dorsal striatum). |
2014-12-05 |
2023-08-13 |
human |
| Nenad Vasic, Michael M Plichta, Robert C Wolf, Andreas J Fallgatter, Zrinka Sosic-Vasic, Georg Grö. Reduced neural error signaling in left inferior prefrontal cortex in young adults with ADHD. Journal of attention disorders. vol 18. issue 8. 2014-12-03. PMID:22660917. |
reduced neural error signaling in left inferior prefrontal cortex in young adults with adhd. |
2014-12-03 |
2023-08-12 |
Not clear |
| Elseline Hoekzema, Susana Carmona, J Antoni Ramos-Quiroga, Vanesa Richarte Fernández, Rosa Bosch, Juan Carlos Soliva, Mariana Rovira, Antonio Bulbena, Adolf Tobeña, Miguel Casas, Oscar Vilarroy. An independent components and functional connectivity analysis of resting state fMRI data points to neural network dysregulation in adult ADHD. Human brain mapping. vol 35. issue 4. 2014-11-25. PMID:23417778. |
we observed a stronger coherence of the left dorsolateral prefrontal cortex (dlpfc) with the dmn component in patients with adhd which correlated with measures of selective attention. |
2014-11-25 |
2023-08-12 |
Not clear |