| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irene Joy I Dela Peña, Chrislean Jun Botanas, June Bryan de la Peña, Raly James Custodio, Ike Dela Peña, Zae Young Ryoo, Bung-Nyun Kim, Jong Hoon Ryu, Hee Jin Kim, Jae Hoon Cheon. The Atxn7-overexpressing mice showed hyperactivity and impulsivity which were ameliorated by atomoxetine treatment: A possible animal model of the hyperactive-impulsive phenotype of ADHD. Progress in neuro-psychopharmacology & biological psychiatry. vol 88. 2019-03-18. PMID:30125623. |
interestingly, treatment with the adhd drug, atomoxetine (3 mg/kg, intraperitoneal), attenuated adhd-like behaviors and reduced atxn7 gene expression in the pfc and str of these mice. |
2019-03-18 |
2023-08-13 |
mouse |
| Cheyenne Allenby, Mary Falcone, Leah Bernardo, E Paul Wileyto, Anthony Rostain, J Russell Ramsay, Caryn Lerman, James Loughea. Transcranial direct current brain stimulation decreases impulsivity in ADHD. Brain stimulation. vol 11. issue 5. 2019-03-11. PMID:29885858. |
transcranial direct current stimulation (tdcs) of the dorsolateral prefrontal cortex (dlpfc) has been shown to modulate cognitive control circuits and could enhance dlpfc activity, leading to improved impulse control in adhd. |
2019-03-11 |
2023-08-13 |
Not clear |
| Yoshifumi Mizuno, Minyoung Jung, Takashi X Fujisawa, Shinichiro Takiguchi, Koji Shimada, Daisuke N Saito, Hirotaka Kosaka, Akemi Tomod. Catechol-O-methyltransferase polymorphism is associated with the cortico-cerebellar functional connectivity of executive function in children with attention-deficit/hyperactivity disorder. Scientific reports. vol 7. issue 1. 2019-01-29. PMID:28687733. |
relative to td controls, children with adhd showed significantly lower functional connectivity of the right crus i/ii with the left dorsolateral prefrontal cortex. |
2019-01-29 |
2023-08-13 |
Not clear |
| Johanna Inhyang Kim, Jae-Won Kim, Jong-Min Lee, Hyuk Jin Yun, Chul-Ho Sohn, Min-Sup Shin, Bongseog Kim, Jonghee Chae, Jaewoo Roh, Bung-Nyun Ki. Interaction between DRD2 and lead exposure on the cortical thickness of the frontal lobe in youth with attention-deficit/hyperactivity disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 82. 2019-01-22. PMID:29169998. |
adhd is characterized by delay in brain maturation, most prominent in the prefrontal cortex (pfc). |
2019-01-22 |
2023-08-13 |
Not clear |
| Johanna Inhyang Kim, Jae-Won Kim, Jong-Min Lee, Hyuk Jin Yun, Chul-Ho Sohn, Min-Sup Shin, Bongseog Kim, Jonghee Chae, Jaewoo Roh, Bung-Nyun Ki. Interaction between DRD2 and lead exposure on the cortical thickness of the frontal lobe in youth with attention-deficit/hyperactivity disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 82. 2019-01-22. PMID:29169998. |
the d2 receptor is also mainly located in the pfc, and animal studies show that lead exposure affects the dopaminergic system of the frontal lobe, indicating an overlap in neural correlates of adhd, drd2, and lead exposure. |
2019-01-22 |
2023-08-13 |
Not clear |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
attention-deficit/hyperactivity disorder (adhd) is closely linked to the dysregulation of dopaminergic and noradrenergic neurotransmission in the fronto-striatal neural network, including the anterior cingulate cortex (acc) and the dorsolateral prefrontal cortex (dlpfc). |
2019-01-14 |
2023-08-13 |
Not clear |
| Jochen Bauer, Anne Werner, Waldemar Kohl, Harald Kugel, Anna Shushakova, Anya Pedersen, Patricia Ohrman. Hyperactivity and impulsivity in adult attention-deficit/hyperactivity disorder is related to glutamatergic dysfunction in the anterior cingulate cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 19. issue 7. 2019-01-14. PMID:27973969. |
impulsivity, a core symptom in patients with adhd, has been repeatedly associated with glutamatergic neurotransmission, and pharmacological treatment of adhd has been shown to reduce glutamate levels in the prefrontal cortex. |
2019-01-14 |
2023-08-13 |
Not clear |
| Vincent Chin-Hung Chen, Chun-Ching Chiu, Li-Jeng Chen, Tsai-Ching Hsu, Bor-Show Tzan. Effects of taurine on striatal dopamine transporter expression and dopamine uptake in SHR rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29694913. |
dopaminergic deficits in the prefrontal cortex and striatum have been attributed to the pathogenesis of attention-deficit hyperactivity disorder (adhd). |
2018-11-05 |
2023-08-13 |
rat |
| Yue Gu, Shuo Miao, Junxia Han, Ke Zeng, Gaoxiang Ouyang, Jian Yang, Xiaoli L. Complexity analysis of fNIRS signals in ADHD children during working memory task. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28400568. |
we found that pe values exhibited significantly negative correlation with the cortical activations (r = -0.515, p = 0.003), and the pe values of right dorsolateral prefrontal cortex in adhd children were significantly larger than those in normal controls (p = 0.027). |
2018-09-18 |
2023-08-13 |
Not clear |
| Yue Gu, Shuo Miao, Junxia Han, Ke Zeng, Gaoxiang Ouyang, Jian Yang, Xiaoli L. Complexity analysis of fNIRS signals in ADHD children during working memory task. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28400568. |
in addition, the pe values of right dorsolateral prefrontal cortex were positively correlated to the adhd index (r = 0.448, p = 0.012). |
2018-09-18 |
2023-08-13 |
Not clear |
| Shiva Khoshnoud, Mohammad Ali Nazari, Mousa Shams. Functional brain dynamic analysis of ADHD and control children using nonlinear dynamical features of EEG signals. Journal of integrative neuroscience. vol 17. issue 1. 2018-08-16. PMID:29172003. |
further, mean approximate entropy was significantly lower in adhd subjects in prefrontal cortex. |
2018-08-16 |
2023-08-13 |
human |
| Anna Sotnikova, Cornelia Soff, Enzo Tagliazucchi, Katja Becker, Michael Siniatchki. Transcranial Direct Current Stimulation Modulates Neuronal Networks in Attention Deficit Hyperactivity Disorder. Brain topography. vol 30. issue 5. 2018-07-27. PMID:28213645. |
since patients with attention deficit hyperactivity disorder (adhd) are characterized by both underactivation of the prefrontal cortex and deficits in wm, the modulation of prefrontal activity with tdcs in adhd patients may increase their wm performance as well as improve the activation and connectivity of the wm network. |
2018-07-27 |
2023-08-13 |
Not clear |
| Anna Sotnikova, Cornelia Soff, Enzo Tagliazucchi, Katja Becker, Michael Siniatchki. Transcranial Direct Current Stimulation Modulates Neuronal Networks in Attention Deficit Hyperactivity Disorder. Brain topography. vol 30. issue 5. 2018-07-27. PMID:28213645. |
after randomization, sixteen adolescents with adhd underwent either anodal tdcs over the left dorsolateral prefrontal cortex (dlpfc, 1 ma, 20 min) or sham stimulation with simultaneous fmri during n-back wm task. |
2018-07-27 |
2023-08-13 |
Not clear |
| Jia Cheng, Aiyi Liu, Michael Y Shi, Zhen Ya. Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28176786. |
disrupted glutamatergic transmission in prefrontal cortex contributes to behavioral abnormality in an animal model of adhd. |
2018-04-24 |
2023-08-13 |
rat |
| Jia Cheng, Aiyi Liu, Michael Y Shi, Zhen Ya. Disrupted Glutamatergic Transmission in Prefrontal Cortex Contributes to Behavioral Abnormality in an Animal Model of ADHD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 10. 2018-04-24. PMID:28176786. |
these results suggest that the disrupted function of ampars in pfc may underlie the behavioral deficits in adolescent shr and enhancing pfc activity could be a treatment strategy for adhd. |
2018-04-24 |
2023-08-13 |
rat |
| Kurt P Schulz, Xiaobo Li, Suzanne M Clerkin, Jin Fan, Olga G Berwid, Jeffrey H Newcorn, Jeffrey M Halperi. Prefrontal and parietal correlates of cognitive control related to the adult outcome of attention-deficit/hyperactivity disorder diagnosed in childhood. Cortex; a journal devoted to the study of the nervous system and behavior. vol 90. 2018-03-22. PMID:28292705. |
the protracted and highly variable development of prefrontal cortex regions that support cognitive control has been purported to shape the adult outcome of attention-deficit/hyperactivity disorder (adhd). |
2018-03-22 |
2023-08-13 |
human |
| Luke J Norman, Christina O Carlisi, Anastasia Christakou, Ana Cubillo, Clodagh M Murphy, Kaylita Chantiluke, Andrew Simmons, Vincent Giampietro, Michael Brammer, David Mataix-Cols, Katya Rubi. Shared and disorder-specific task-positive and default mode network dysfunctions during sustained attention in paediatric Attention-Deficit/Hyperactivity Disorder and obsessive/compulsive disorder. NeuroImage. Clinical. vol 15. 2018-03-09. PMID:28529874. |
adhd and ocd patients shared left insula/ventral ifg underactivation and increased activation in posterior default mode network relative to controls, but had disorder-specific overactivation in anterior default mode regions, in dorsal anterior cingulate for adhd and in anterior ventromedial prefrontal cortex for ocd. |
2018-03-09 |
2023-08-13 |
Not clear |
| Michie Odle, Judith A Ouellett. Anticipatory Electrodermal Response as a Differentiating Somatic Marker Between Children with ADHD and Controls. Applied psychophysiology and biofeedback. vol 41. issue 4. 2018-03-05. PMID:27272970. |
results indicate that the adhd group exhibited significantly lower autonomic reactivity to anticipated consequences, evidencing a neuropsychological profile similar to patients with lesions in the ventromedial prefrontal cortex. |
2018-03-05 |
2023-08-13 |
Not clear |
| Analucia A Alegria, Melanie Wulff, Helen Brinson, Gareth J Barker, Luke J Norman, Daniel Brandeis, Daniel Stahl, Anthony S David, Eric Taylor, Vincent Giampietro, Katya Rubi. Real-time fMRI neurofeedback in adolescents with attention deficit hyperactivity disorder. Human brain mapping. vol 38. issue 6. 2018-03-01. PMID:28342214. |
a randomized controlled trial tested the efficacy of rtfmri-nf of right inferior prefrontal cortex (rifg), a key region that is compromised in adhd and upregulated with psychostimulants, on improvement of adhd symptoms, cognition, and inhibitory fmri activation. |
2018-03-01 |
2023-08-13 |
human |
| Cornelia Soff, Anna Sotnikova, Hanna Christiansen, Katja Becker, Michael Siniatchki. Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 1. 2018-02-27. PMID:27853926. |
as patients with attention deficit hyperactivity disorder (adhd) are characterized by both underactivation of the prefrontal cortex and deficits in working memory that correlate with clinical symptoms, it is hypothesized that the modulation of prefrontal activity with tdcs in patients with adhd increases performance in working memory and reduces symptoms of adhd. |
2018-02-27 |
2023-08-13 |
Not clear |