| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julian Macoveanu, Iselin Meluken, Henry W Chase, Mary L Phillips, Lars Vedel Kessing, Hartwig Roman Siebner, Maj Vinberg, Kamilla W Miskowia. Reduced frontostriatal response to expected value and reward prediction error in remitted monozygotic twins with mood disorders and their unaffected high-risk co-twins. Psychological medicine. vol 51. issue 10. 2021-11-03. PMID:32115012. |
depressive episodes experienced in unipolar (ud) and bipolar (bd) disorders are characterized by anhedonia and have been associated with abnormalities in reward processes related to reward valuation and error prediction. |
2021-11-03 |
2023-08-13 |
Not clear |
| Shijing Wang, Francesco Leri, Sakina J Rizv. Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33631251. |
the modern framework of anhedonia extends the definition from impaired consummatory pleasure or interest in rewards to a broad spectrum of deficits that impact functions such as reward anticipation, approach motivation, effort expenditure, reward valuation, expectation, and reward-cue association learning. |
2021-11-01 |
2023-08-13 |
Not clear |
| Shijing Wang, Francesco Leri, Sakina J Rizv. Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33631251. |
as well, serotonin, norepinephrine, opioids, glutamate, gamma aminobutyric acid (gaba), and acetylcholine are also involved in anhedonia, and medications targeting these systems may also potentially normalize reward processing in depression. |
2021-11-01 |
2023-08-13 |
Not clear |
| Rebecca Watson, Kate Harvey, Laura Pass, Ciara McCabe, Shirley Reynold. A qualitative study exploring adolescents' experience of brief behavioural activation for depression and its impact on the symptom of anhedonia. Psychology and psychotherapy. vol 94. issue 2. 2021-10-28. PMID:32918843. |
anhedonia, the loss of interest and pleasure, is a core symptom of depression and is associated with deficits in reward processing. |
2021-10-28 |
2023-08-13 |
Not clear |
| Peter L Rosencrans, Lori A Zoellner, Norah C Feen. A network approach to posttraumatic stress disorder: Comparing interview and self-report networks. Psychological trauma : theory, research, practice and policy. 2021-10-21. PMID:34672659. |
trauma-related fear (e.g., reexperiencing), impaired reward (e.g., anhedonia), and interpersonal (e.g., detachment) processes may be functionally intertwined, giving rise to chronic psychopathology after a trauma. |
2021-10-21 |
2023-08-13 |
Not clear |
| Martine Skumlien, Christelle Langley, Will Lawn, Valerie Voon, H Valerie Curran, Jonathan P Roiser, Barbara J Sahakia. The acute and non-acute effects of cannabis on reward processing: A systematic review. Neuroscience and biobehavioral reviews. vol 130. 2021-10-20. PMID:34509513. |
cannabis use has historically been thought to cause amotivation, but the relationship between cannabis and apathy, anhedonia, and reward processing remains poorly characterised. |
2021-10-20 |
2023-08-13 |
Not clear |
| Gabriela K Khazanov, Courtney N Forbes, Barnaby D Dunn, Michael E Thas. Addressing anhedonia to increase depression treatment engagement. The British journal of clinical psychology. 2021-10-09. PMID:34625993. |
anhedonia, or reward system dysfunction, is associated with poorer treatment outcomes among depressed individuals. |
2021-10-09 |
2023-08-13 |
Not clear |
| Gabriela K Khazanov, Courtney N Forbes, Barnaby D Dunn, Michael E Thas. Addressing anhedonia to increase depression treatment engagement. The British journal of clinical psychology. 2021-10-09. PMID:34625993. |
we then propose interventions to improve treatment initiation and continuation by addressing deficits in each component of reward functioning, focusing on modifications of existing evidence-based interventions to meet the needs of individuals with heightened anhedonia. |
2021-10-09 |
2023-08-13 |
Not clear |
| Sally Pessin, Carissa L Philippi, Leah Reyna, Nathan Buggar, Steven E Bruc. Influence of anhedonic symptom severity on reward circuit connectivity in PTSD. Behavioural brain research. vol 407. 2021-10-06. PMID:33775774. |
anhedonia, marked by deficits in reward processing, is a prominent symptom of several psychiatric conditions and has been shown to influence functional connectivity between reward-related regions. |
2021-10-06 |
2023-08-13 |
Not clear |
| Sally Pessin, Carissa L Philippi, Leah Reyna, Nathan Buggar, Steven E Bruc. Influence of anhedonic symptom severity on reward circuit connectivity in PTSD. Behavioural brain research. vol 407. 2021-10-06. PMID:33775774. |
however, the unique influence of anhedonia severity on reward circuit connectivity in posttraumatic stress disorder (ptsd) remains unclear. |
2021-10-06 |
2023-08-13 |
Not clear |
| Sally Pessin, Carissa L Philippi, Leah Reyna, Nathan Buggar, Steven E Bruc. Influence of anhedonic symptom severity on reward circuit connectivity in PTSD. Behavioural brain research. vol 407. 2021-10-06. PMID:33775774. |
our findings suggest that reward circuit dysfunction at rest is associated with anhedonia in ptsd. |
2021-10-06 |
2023-08-13 |
Not clear |
| Qi Liu, Benjamin Ely, Sherry Simkovic, Annie Tao, Rachel Wolchok, Carmen M Alonso, Vilma Gabba. Correlates of C-reactive protein with neural reward circuitry in adolescents with psychiatric symptoms. Brain, behavior, & immunity - health. vol 9. 2021-09-29. PMID:33381770. |
we previously reported relationships between blood cytokine levels and anhedonia, the decreased capacity to experience pleasure, as well as with reward brain activation in adolescents with psychiatric symptoms. |
2021-09-29 |
2023-08-13 |
Not clear |
| Rebecca Seidemann, Or Duek, Ruonan Jia, Ifat Levy, Ilan Harpaz-Rote. The Reward System and Post-Traumatic Stress Disorder: Does Trauma Affect the Way We Interact With Positive Stimuli? Chronic stress (Thousand Oaks, Calif.). vol 5. 2021-09-20. PMID:33718742. |
although anhedonia is an important construct of the disorder, the relationship between ptsd and reward functioning is still under-researched. |
2021-09-20 |
2023-08-13 |
Not clear |
| Alessandra Borsini, Amelia St John Wallis, Patricia Zunszain, Carmine Maria Pariante, Matthew J Kempto. Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression. Cognitive, affective & behavioral neuroscience. vol 20. issue 4. 2021-08-31. PMID:32472419. |
characterizing anhedonia: a systematic review of neuroimaging across the subtypes of reward processing deficits in depression. |
2021-08-31 |
2023-08-13 |
human |
| Alessandra Borsini, Amelia St John Wallis, Patricia Zunszain, Carmine Maria Pariante, Matthew J Kempto. Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression. Cognitive, affective & behavioral neuroscience. vol 20. issue 4. 2021-08-31. PMID:32472419. |
anhedonia is a key symptom of major depressive disorder (mdd) and comprises behavioural deficits in three reward processing subtypes: reward liking, reward wanting, and reward learning. |
2021-08-31 |
2023-08-13 |
human |
| Simone Cunningham, Raegan Mazurka, Katherine E Wynne-Edwards, Roumen V Milev, Diego A Pizzagalli, Sidney Kennedy, Kate L Harknes. Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. Journal of affective disorders. vol 293. 2021-08-27. PMID:34153656. |
cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. |
2021-08-27 |
2023-08-13 |
human |
| Simone Cunningham, Raegan Mazurka, Katherine E Wynne-Edwards, Roumen V Milev, Diego A Pizzagalli, Sidney Kennedy, Kate L Harknes. Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. Journal of affective disorders. vol 293. 2021-08-27. PMID:34153656. |
the goal of this study was to examine the relation of responses to stress and reward, and to determine if this relation is moderated by depression diagnosis, anhedonia, and sex. |
2021-08-27 |
2023-08-13 |
human |
| Simone Cunningham, Raegan Mazurka, Katherine E Wynne-Edwards, Roumen V Milev, Diego A Pizzagalli, Sidney Kennedy, Kate L Harknes. Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. Journal of affective disorders. vol 293. 2021-08-27. PMID:34153656. |
in addition, among depressed participants with high levels of anhedonia, higher cortisol output during the tsst was significantly associated with higher overall response bias to reward. |
2021-08-27 |
2023-08-13 |
human |
| Simone Cunningham, Raegan Mazurka, Katherine E Wynne-Edwards, Roumen V Milev, Diego A Pizzagalli, Sidney Kennedy, Kate L Harknes. Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia. Journal of affective disorders. vol 293. 2021-08-27. PMID:34153656. |
further, in depression, our findings suggest that anhedonia may represent a specific phenotype in which the stress and reward systems are particularly tuned together. |
2021-08-27 |
2023-08-13 |
human |
| Vibe G Frokjae. Pharmacological sex hormone manipulation as a risk model for depression. Journal of neuroscience research. vol 98. issue 7. 2021-08-26. PMID:32399989. |
further, the gnrha model suggest that key brain regions in the reward circuit are less engaged in positive stimuli when undergoing sex hormone manipulation, which may underlie anhedonia. |
2021-08-26 |
2023-08-13 |
human |