| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benjamin A Ely, Tram N B Nguyen, Russell H Tobe, Audrey M Walker, Vilma Gabba. Multimodal Investigations of Reward Circuitry and Anhedonia in Adolescent Depression. Frontiers in psychiatry. vol 12. 2021-08-10. PMID:34366915. |
multimodal investigations of reward circuitry and anhedonia in adolescent depression. |
2021-08-10 |
2023-08-13 |
Not clear |
| Showall Moazzam, Jessica S Jarmasz, Yan Jin, Tabrez J Siddiqui, Peter A Cattin. Effects of high fat diet-induced obesity and pregnancy on prepartum and postpartum maternal mouse behavior. Psychoneuroendocrinology. vol 126. 2021-07-30. PMID:33497916. |
anhedonia, a measure of impaired reward function, is an endophenotype of depression and was assessed by sucrose preference test pre- and post-weaning in dams. |
2021-07-30 |
2023-08-13 |
mouse |
| Rui Liu, Yun Wang, Xiongying Chen, Zhifang Zhang, Le Xiao, Yuan Zho. Anhedonia correlates with functional connectivity of the nucleus accumbens subregions in patients with major depressive disorder. NeuroImage. Clinical. vol 30. 2021-07-30. PMID:33662708. |
the nucleus accumbens (nac) is an important region in reward circuit that has been linked with anhedonia, which is a characteristic symptom of major depressive disorder (mdd). |
2021-07-30 |
2023-08-13 |
Not clear |
| Jie Fan, Wanting Liu, Jie Xia, Sihui Li, Feng Gao, Jiang Zhu, Yan Han, Huan Zhou, Haiyan Liao, Jinyao Yi, Changlian Tan, Xiongzhao Zh. Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls. Human brain mapping. vol 42. issue 2. 2021-07-08. PMID:33030766. |
childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls. |
2021-07-08 |
2023-08-13 |
Not clear |
| Jie Fan, Wanting Liu, Jie Xia, Sihui Li, Feng Gao, Jiang Zhu, Yan Han, Huan Zhou, Haiyan Liao, Jinyao Yi, Changlian Tan, Xiongzhao Zh. Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls. Human brain mapping. vol 42. issue 2. 2021-07-08. PMID:33030766. |
the present study tested the hypothesis that ct have effects on specific types of anhedonia in depression via reward system. |
2021-07-08 |
2023-08-13 |
Not clear |
| Jie Fan, Wanting Liu, Jie Xia, Sihui Li, Feng Gao, Jiang Zhu, Yan Han, Huan Zhou, Haiyan Liao, Jinyao Yi, Changlian Tan, Xiongzhao Zh. Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls. Human brain mapping. vol 42. issue 2. 2021-07-08. PMID:33030766. |
to do so, we evaluated different aspects of anhedonia and resting-state functional connectivity (fc) in reward system among 66 patients with mdd (44 with moderate-to-severe and 22 with no or low ct), and 57 healthy controls (hc; 23 with moderate-to-severe and 34 with no or low ct). |
2021-07-08 |
2023-08-13 |
Not clear |
| Jie Fan, Wanting Liu, Jie Xia, Sihui Li, Feng Gao, Jiang Zhu, Yan Han, Huan Zhou, Haiyan Liao, Jinyao Yi, Changlian Tan, Xiongzhao Zh. Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls. Human brain mapping. vol 42. issue 2. 2021-07-08. PMID:33030766. |
these findings highlight specific types of anhedonia and the core reward system as targets of ct. blunted hedonic responses via decreased coupling within core reward system may be involved in the mechanism of depression following ct. |
2021-07-08 |
2023-08-13 |
Not clear |
| Zhao Wang, Qi Li, Lu Nie, Ya Zhen. Neural dynamics of monetary and social reward processing in social anhedonia. Social cognitive and affective neuroscience. vol 15. issue 9. 2021-07-06. PMID:32945882. |
neural dynamics of monetary and social reward processing in social anhedonia. |
2021-07-06 |
2023-08-13 |
human |
| Zhao Wang, Qi Li, Lu Nie, Ya Zhen. Neural dynamics of monetary and social reward processing in social anhedonia. Social cognitive and affective neuroscience. vol 15. issue 9. 2021-07-06. PMID:32945882. |
however, the neural portrait of social anhedonia remains elusive because of heterogeneities of reward type and reward dynamics in previous studies. |
2021-07-06 |
2023-08-13 |
human |
| Zhao Wang, Qi Li, Lu Nie, Ya Zhen. Neural dynamics of monetary and social reward processing in social anhedonia. Social cognitive and affective neuroscience. vol 15. issue 9. 2021-07-06. PMID:32945882. |
our findings provide preliminary evidence for neural aberrations of the reward system in social anhedonia, which is contingent upon reward type and reward dynamics. |
2021-07-06 |
2023-08-13 |
human |
| Neeti D Mehta, Jennifer S Stevens, Zhihao Li, Charles F Gillespie, Negar Fani, Vasiliki Michopoulos, Jennifer C Felge. Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women. Social cognitive and affective neuroscience. vol 15. issue 10. 2021-07-02. PMID:32291455. |
inflammation, reward circuitry and symptoms of anhedonia and ptsd in trauma-exposed women. |
2021-07-02 |
2023-08-13 |
human |
| Neeti D Mehta, Jennifer S Stevens, Zhihao Li, Charles F Gillespie, Negar Fani, Vasiliki Michopoulos, Jennifer C Felge. Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women. Social cognitive and affective neuroscience. vol 15. issue 10. 2021-07-02. PMID:32291455. |
we examined resting-state functional mri in a high-trauma inner-city population of african-american women (n = 56), who reported on average five different types of trauma exposures, to investigate whether inflammation correlated with functional connectivity (fc) in corticostriatal reward circuitry in association with symptoms of anhedonia and ptsd. |
2021-07-02 |
2023-08-13 |
human |
| Neeti D Mehta, Jennifer S Stevens, Zhihao Li, Charles F Gillespie, Negar Fani, Vasiliki Michopoulos, Jennifer C Felge. Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women. Social cognitive and affective neuroscience. vol 15. issue 10. 2021-07-02. PMID:32291455. |
results suggest that inflammation contributes to compromised reward circuitry and symptoms of anhedonia and ptsd in trauma-exposed women. |
2021-07-02 |
2023-08-13 |
human |
| Katharine Dunlop, Sakina J Rizvi, Sidney H Kennedy, Stefanie Hassel, Stephen C Strother, Jacqueline K Harris, Mojdeh Zamyadi, Stephen R Arnott, Andrew D Davis, Farrokh Mansouri, Laura Schulze, Amanda K Ceniti, Raymond W Lam, Roumen Milev, Susan Rotzinger, Jane A Foster, Benicio N Frey, Sagar V Parikh, Claudio N Soares, Rudolf Uher, Gustavo Turecki, Glenda M MacQueen, Jonathan Downa. Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 8. 2021-06-23. PMID:32349119. |
anhedonia is thought to reflect deficits in reward processing that are associated with abnormal activity in mesocorticolimbic brain regions. |
2021-06-23 |
2023-08-13 |
human |
| Katharine Dunlop, Sakina J Rizvi, Sidney H Kennedy, Stefanie Hassel, Stephen C Strother, Jacqueline K Harris, Mojdeh Zamyadi, Stephen R Arnott, Andrew D Davis, Farrokh Mansouri, Laura Schulze, Amanda K Ceniti, Raymond W Lam, Roumen Milev, Susan Rotzinger, Jane A Foster, Benicio N Frey, Sagar V Parikh, Claudio N Soares, Rudolf Uher, Gustavo Turecki, Glenda M MacQueen, Jonathan Downa. Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 8. 2021-06-23. PMID:32349119. |
clinical correlates of reward processing were assessed at baseline using validated scales to measure anhedonia, and a monetary incentive delay (mid) task during functional neuroimaging was completed at baseline and after 2 weeks of treatment. |
2021-06-23 |
2023-08-13 |
human |
| Diego A Pizzagalli, Moria Smoski, Yuen-Siang Ang, Alexis E Whitton, Gerard Sanacora, Sanjay J Mathew, John Nurnberger, Sarah H Lisanby, Dan V Iosifescu, James W Murrough, Hongqiu Yang, Richard D Weiner, Joseph R Calabrese, Wayne Goodman, William Z Potter, Andrew D Krysta. Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS). Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32544925. |
taking a proof-of-mechanism approach under the auspices of the national institute of mental health fast-fail initiative, we were the first to show that, in a transdiagnostic sample screened for elevated self-reported anhedonia, 8 weeks of treatment with a kappa-opioid receptor (kor) antagonist resulted in significantly higher reward-related activation in one of the core hubs of the brain reward system (the ventral striatum), better reward learning in the probabilistic reward task (prt), and lower anhedonic symptoms, relative to 8 weeks of placebo. |
2021-06-23 |
2023-08-13 |
Not clear |
| Andrea Pelletier-Baldelli, Joseph M Orr, Jessica A Bernard, Vijay A Mitta. Social reward processing: A biomarker for predicting psychosis risk? Schizophrenia research. vol 226. 2021-06-17. PMID:30093351. |
although interesting relationships were found linking neural reward response and connectivity with social, anticipatory, and consummatory anhedonia in the chr group, results are difficult to interpret in light of task limitations. |
2021-06-17 |
2023-08-13 |
Not clear |
| Yana Lokshina, Tetiana Nickelsen, Israel Liberzo. Reward Processing and Circuit Dysregulation in Posttraumatic Stress Disorder. Frontiers in psychiatry. vol 12. 2021-06-15. PMID:34122157. |
however, the neurobiology of anhedonia and emotional numbing in ptsd, that have been conceptualized as reward processing deficits - reward wanting (anticipation of reward) and reward liking (satisfaction with reward outcome), respectively, remains largely unexplored. |
2021-06-15 |
2023-08-13 |
human |
| Yana Lokshina, Tetiana Nickelsen, Israel Liberzo. Reward Processing and Circuit Dysregulation in Posttraumatic Stress Disorder. Frontiers in psychiatry. vol 12. 2021-06-15. PMID:34122157. |
studying reward processing in ptsd will not only advance the understanding of their link, but also could enhance current treatment approaches by specifically targeting anhedonia and emotional symptoms in ptsd patients. |
2021-06-15 |
2023-08-13 |
human |
| Hiroki Moriya, Mikael Tiger, Amane Tateno, Takeshi Sakayori, Takahiro Masuoka, WooChan Kim, Ryosuke Arakawa, Yoshiro Okub. Low dopamine transporter binding in the nucleus accumbens in geriatric patients with severe depression. Psychiatry and clinical neurosciences. vol 74. issue 8. 2021-06-09. PMID:32363761. |
especially, mdd in geriatric patients is characterized by anhedonia, which is assumed to be associated with reduced dopamine neurotransmission in the reward system. |
2021-06-09 |
2023-08-13 |
Not clear |