| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer L Whitwell, Stephen D Weigand, Maria M Shiung, Bradley F Boeve, Tanis J Ferman, Glenn E Smith, David S Knopman, Ronald C Petersen, Eduardo E Benarroch, Keith A Josephs, Clifford R Jac. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain : a journal of neurology. vol 130. issue Pt 3. 2007-04-16. PMID:17267521. |
significantly greater loss in the hippocampus and temporo-parietal cortex was observed in the alzheimer's disease patients when the two patient groups were compared. |
2007-04-16 |
2023-08-12 |
Not clear |
| Jennifer L Whitwell, Stephen D Weigand, Maria M Shiung, Bradley F Boeve, Tanis J Ferman, Glenn E Smith, David S Knopman, Ronald C Petersen, Eduardo E Benarroch, Keith A Josephs, Clifford R Jac. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain : a journal of neurology. vol 130. issue Pt 3. 2007-04-16. PMID:17267521. |
a pattern of relatively focused atrophy of the midbrain, hypothalamus and si, with a relative sparing of the hippocampus and temporoparietal cortex is, therefore, suggestive of dlb and this may aid in the differentiation of dlb from alzheimer's disease. |
2007-04-16 |
2023-08-12 |
Not clear |
| Jian-Guo Cui, James M Hill, Yuhai Zhao, Walter J Luki. Expression of inflammatory genes in the primary visual cortex of late-stage Alzheimer's disease. Neuroreport. vol 18. issue 2. 2007-04-10. PMID:17301674. |
in this study, using dna arrays and western immunoassay, gene expression patterns were examined in the thalamus and primary visual cortex of moderate-stage and late-stage alzheimer's disease and age-matched controls using a set of proinflammatory genes known to be upregulated in the temporal lobe neocortex and hippocampus of moderate-stage alzheimer's disease. |
2007-04-10 |
2023-08-12 |
Not clear |
| D P Devanand, G Pradhaban, X Liu, A Khandji, S De Santi, S Segal, H Rusinek, G H Pelton, L S Honig, R Mayeux, Y Stern, M H Tabert, M J de Leo. Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology. vol 68. issue 11. 2007-04-05. PMID:17353470. |
hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of alzheimer disease. |
2007-04-05 |
2023-08-12 |
Not clear |
| D P Devanand, G Pradhaban, X Liu, A Khandji, S De Santi, S Segal, H Rusinek, G H Pelton, L S Honig, R Mayeux, Y Stern, M H Tabert, M J de Leo. Hippocampal and entorhinal atrophy in mild cognitive impairment: prediction of Alzheimer disease. Neurology. vol 68. issue 11. 2007-04-05. PMID:17353470. |
to evaluate the utility of mri hippocampal and entorhinal cortex atrophy in predicting conversion from mild cognitive impairment (mci) to alzheimer disease (ad). |
2007-04-05 |
2023-08-12 |
Not clear |
| Ganesh M Shankar, Brenda L Bloodgood, Matthew Townsend, Dominic M Walsh, Dennis J Selkoe, Bernardo L Sabatin. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 11. 2007-04-05. PMID:17360908. |
alzheimer's disease (ad) is characterized by decreased synapse density in hippocampus and neocortex, and synapse loss is the strongest anatomical correlate of the degree of clinical impairment. |
2007-04-05 |
2023-08-12 |
human |
| Hong-Yan Zhu, Hou-Fu Guo, Hai-Long Hou, Ya-Jing Liu, Shu-Li Sheng, Jiang-Ning Zho. Increased expression of the Nogo receptor in the hippocampus and its relation to the neuropathology in Alzheimer's disease. Human pathology. vol 38. issue 3. 2007-04-04. PMID:17188332. |
increased expression of the nogo receptor in the hippocampus and its relation to the neuropathology in alzheimer's disease. |
2007-04-04 |
2023-08-12 |
human |
| E Burgos-Ramos, A Hervás-Aguilar, L Puebla-Jiménez, M C Boyano-Adánez, E Arilla-Ferreir. Chronic but not acute intracerebroventricular administration of amyloid beta-peptide(25-35) decreases somatostatin content, adenylate cyclase activity, somatostatin-induced inhibition of adenylate cyclase activity, and adenylate cyclase I levels in the rat hippocampus. Journal of neuroscience research. vol 85. issue 2. 2007-03-29. PMID:17086550. |
although alterations in adenylate cyclase (ac) activity and somatostatin (srif) receptor density have been reported in alzheimer's disease, the effects of amyloid beta-peptide (abeta) on these parameters in the hippocampus are unknown. |
2007-03-29 |
2023-08-12 |
rat |
| A J Bastos-Leite, J H van Waesberghe, A L Oen, W M van der Flier, P Scheltens, F Barkho. Hippocampal sulcus width and cavities: comparison between patients with Alzheimer disease and nondemented elderly subjects. AJNR. American journal of neuroradiology. vol 27. issue 10. 2007-03-29. PMID:17110684. |
hippocampal sulcus width and cavities: comparison between patients with alzheimer disease and nondemented elderly subjects. |
2007-03-29 |
2023-08-12 |
human |
| A J Bastos-Leite, J H van Waesberghe, A L Oen, W M van der Flier, P Scheltens, F Barkho. Hippocampal sulcus width and cavities: comparison between patients with Alzheimer disease and nondemented elderly subjects. AJNR. American journal of neuroradiology. vol 27. issue 10. 2007-03-29. PMID:17110684. |
we hypothesized that either hippocampal sulcus enlargement or an increase in number or size of hippocampal cavities could be associated with medial temporal lobe atrophy (mta) occurring in alzheimer disease. |
2007-03-29 |
2023-08-12 |
human |
| Milena Damjanac, Agnès Rioux Bilan, Laurence Barrier, Raymond Pontcharraud, Cantereau Anne, Jacques Hugon, Guylène Pag. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease. Brain research. vol 1128. issue 1. 2007-03-27. PMID:17125750. |
in this study, we analyzed the staining of fluoro-jade b alone or combined with specific markers for detection of glial fibrillary acidic protein (gfap) or activated cd68 microglia in the double app(sl)/ps1 ki transgenic mice of alzheimer's disease (ad), which display a massive neuronal loss in the ca1 region of the hippocampus. |
2007-03-27 |
2023-08-12 |
mouse |
| John K Wung, George Perry, Aaron Kowalski, Peggy L R Harris, Glenda M Bishop, Mehul A Trivedi, Sterling C Johnson, Mark A Smith, David T Denhardt, Craig S Atwoo. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Current Alzheimer research. vol 4. issue 1. 2007-03-27. PMID:17316167. |
since these functions of opn, and the events that it regulates, are involved with neurodegeneration, we examined whether opn was differentially expressed in the hippocampus of the alzheimer's disease (ad) compared with age-matched (59-93 years) control brain. |
2007-03-27 |
2023-08-12 |
human |
| Xiao-Rui Cheng, Wen-Xia Zhou, Yong-Xiang Zhang, Dong-Sheng Zhou, Rui-Fu Yang, Ling-Feng Che. Differential gene expression profiles in the hippocampus of senescence-accelerated mouse. Neurobiology of aging. vol 28. issue 4. 2007-03-22. PMID:16569465. |
these results indicated the profiles of gene expression in the hippocampus of samp8 and samr1 were significantly different, which may play important roles in the age-related cognitive deficit in samp8, suggesting those genes related to the cognitive deficient or pathology change in the brain of samp8 may be potential gene targets for alzheimer's disease therapy. |
2007-03-22 |
2023-08-12 |
mouse |
| Keiko Mizuno, Florian Plattner, K Peter Gies. Expression of p25 impairs contextual learning but not latent inhibition in mice. Neuroreport. vol 17. issue 18. 2007-03-19. PMID:17179867. |
female, but not male, transgenic mice expressing low levels of p25 have enhanced hippocampal long-term potentiation and improved spatial learning, raising the hypothesis that p25 may compensate for early learning deficits in alzheimer's disease in a sex-dependent manner. |
2007-03-19 |
2023-08-12 |
mouse |
| Marie Chupin, A Romain Mukuna-Bantumbakulu, Dominique Hasboun, Eric Bardinet, Sylvain Baillet, Serge Kinkingnéhun, Louis Lemieux, Bruno Dubois, Line Garner. Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease. NeuroImage. vol 34. issue 3. 2007-03-15. PMID:17178234. |
anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: method and validation on controls and patients with alzheimer's disease. |
2007-03-15 |
2023-08-12 |
human |
| Ana Pocivavsek, Laura Icenogle, Edward D Levi. Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats. Psychopharmacology. vol 188. issue 4. 2007-03-13. PMID:16715255. |
decreased hippocampal nicotinic receptor concentration is associated with cognitive impairment in schizophrenia and alzheimer's disease. |
2007-03-13 |
2023-08-12 |
rat |
| Hyoung-gon Lee, Masumi Ueda, Xiongwei Zhu, George Perry, Mark A Smit. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? Journal of neuroscience research. vol 84. issue 8. 2007-03-13. PMID:16998902. |
consistently with an increase in tgf-beta in alzheimer's disease, we found significant increases in phospho-smad2, a major downstream signaling molecule of tgf-beta, in hippocampal neurons of alzheimer's disease compared with age-matched control patients. |
2007-03-13 |
2023-08-12 |
Not clear |
| Hai-Long Hou, Yu-Xian Shen, Hong-Yan Zhu, Hao Sun, Xue-Bo Yan, Hui Fang, Jiang-Ning Zho. Alterations of hHrd1 expression are related to hyperphosphorylated tau in the hippocampus in Alzheimer's disease. Journal of neuroscience research. vol 84. issue 8. 2007-03-13. PMID:17044033. |
alterations of hhrd1 expression are related to hyperphosphorylated tau in the hippocampus in alzheimer's disease. |
2007-03-13 |
2023-08-12 |
Not clear |
| Wendy M Brooks, Patrick J Lynch, Catherine C Ingle, Alexander Hatton, Piers C Emson, Richard L M Faull, Mike P Starke. Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain research. vol 1127. issue 1. 2007-03-09. PMID:17109828. |
using microarray analysis and quantitative rt-pcr, the expression of mrna transcripts involved in glucose metabolism was investigated in alzheimer's diseased post-mortem human hippocampal samples. |
2007-03-09 |
2023-08-12 |
human |
| Peng Yang, K Adam Baker, Theo Hag. The ADAMs family: coordinators of nervous system development, plasticity and repair. Progress in neurobiology. vol 79. issue 2. 2007-03-08. PMID:16824663. |
for example, over-expression of adam10, one of the alpha-secretases for app, can prevent amyloid formation and hippocampal defects in an alzheimer mouse model. |
2007-03-08 |
2023-08-12 |
mouse |