| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Mevel, G Chetelat, B Desgranges, F Eustach. [Alzheimer's disease, hippocampus and neuroimaging]. L'Encephale. vol 32 Pt 4. 2007-05-18. PMID:17356489. |
[alzheimer's disease, hippocampus and neuroimaging]. |
2007-05-18 |
2023-08-12 |
Not clear |
| Lei Wang, Faisal Beg, Tilak Ratnanather, Can Ceritoglu, Laurent Younes, John C Morris, John G Csernansky, Michael I Mille. Large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the Alzheimer type. IEEE transactions on medical imaging. vol 26. issue 4. 2007-05-16. PMID:17427733. |
large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the alzheimer type. |
2007-05-16 |
2023-08-12 |
human |
| Julio Santos-Torres, Antonio Fuente, Jose Maria Criado, Adelaida Sanchez Riolobos, Margarita Heredia, Javier Yajey. Glutamatergic synaptic depression by synthetic amyloid beta-peptide in the medial septum. Journal of neuroscience research. vol 85. issue 3. 2007-05-14. PMID:17171714. |
the medial septum/diagonal band region, which participates in learning and memory processes via its cholinergic and gabaergic projection to the hippocampus, is one of the structures affected by beta amyloid (betaa) deposition in alzheimer's disease (ad). |
2007-05-14 |
2023-08-12 |
rat |
| Chen Zhang, Elizabeth McNeil, Lindsay Dressler, Robert Sima. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Experimental neurology. vol 204. issue 1. 2007-05-10. PMID:17070803. |
long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial alzheimer's disease. |
2007-05-10 |
2023-08-12 |
mouse |
| Chen Zhang, Elizabeth McNeil, Lindsay Dressler, Robert Sima. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Experimental neurology. vol 204. issue 1. 2007-05-10. PMID:17070803. |
neurogenesis in the adult hippocampus has been implicated in regulating long-term memory and mood, but its integrity in alzheimer's disease (ad) is uncertain. |
2007-05-10 |
2023-08-12 |
mouse |
| Sander M Daselaar, Mathias S Fleck, Ian G Dobbins, David J Madden, Roberto Cabez. Effects of healthy aging on hippocampal and rhinal memory functions: an event-related fMRI study. Cerebral cortex (New York, N.Y. : 1991). vol 16. issue 12. 2007-05-08. PMID:16421332. |
this finding has important clinical implications because early alzheimer's disease impairs both hippocampus and rhinal cortex. |
2007-05-08 |
2023-08-12 |
Not clear |
| Marco Pugliese, Carlo Gangitano, Sabrina Ceccariglia, Josep Lluís Carrasco, Aurora Del Fà, Manuel José Rodríguez, Fabrizio Michetti, Joan Mascort, Nicole Mah. Canine cognitive dysfunction and the cerebellum: acetylcholinesterase reduction, neuronal and glial changes. Brain research. vol 1139. 2007-05-08. PMID:17292335. |
the specific functional and pathological alterations observed in alzheimer's disease are less severe in the cerebellum than in other brain areas, particularly the entorhinal cortex and hippocampus. |
2007-05-08 |
2023-08-12 |
human |
| M Dumont, R Lalonde, J-F Ghersi-Egea, K Fukuchi, C Straziell. Regional acetylcholinesterase activity and its correlation with behavioral performances in 15-month old transgenic mice expressing the human C99 fragment of APP. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 9. 2007-05-02. PMID:16362638. |
the ache activity of tg13592 mice was altered in several regions implicated in the functional loop of regulation between septum and hippocampus, vulnerable in alzheimer pathology and critically involved in cognitive functions. |
2007-05-02 |
2023-08-12 |
mouse |
| J Romero López, E Rivas Infante, J L Maciñeiras Montero, M J Montero Carreter. [Cerebral amyloid angiopathy, recurrent intracerebral haemorrhages and Down's syndrome]. Neurologia (Barcelona, Spain). vol 21. issue 10. 2007-05-01. PMID:17106827. |
an autopsy showed lesions in leptomeningeal and cortical arteries which are characteristic of caa in addition to anatomicopathological changes of alzheimer s disease that were mostly seen in entorhinal cortex and hippocampus. |
2007-05-01 |
2023-08-12 |
Not clear |
| Walter J Luki. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport. vol 18. issue 3. 2007-04-27. PMID:17314675. |
micro-rna speciation in fetal, adult and alzheimer's disease hippocampus. |
2007-04-27 |
2023-08-12 |
Not clear |
| Walter J Luki. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport. vol 18. issue 3. 2007-04-27. PMID:17314675. |
this study examined micro-rna abundance in the hippocampal region of fetal, adult and alzheimer's disease brain. |
2007-04-27 |
2023-08-12 |
Not clear |
| Walter J Luki. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport. vol 18. issue 3. 2007-04-27. PMID:17314675. |
the data indicate that micro-rnas encoding mir-9, mir-124a, mir-125b, mir-128, mir-132 and mir-219 are abundantly represented in fetal hippocampus, are differentially regulated in aged brain, and an alteration in specific micro-rna complexity occurs in alzheimer hippocampus. |
2007-04-27 |
2023-08-12 |
Not clear |
| Emriye Kart-Teke, Ekrem Dere, Marcus L Brandão, Joseph P Huston, Maria A De Souza Silv. Reinstatement of episodic-like memory in rats by neurokinin-1 receptor antagonism. Neurobiology of learning and memory. vol 87. issue 3. 2007-04-26. PMID:17079168. |
since nk-1-r antagonists have anxiolytic and promestic properties and induce hippocampal acetylcholine release at lower doses, they might be effective in the alleviation of the cognitive deficits and increased anxiety seen in early stages of alzheimer's disease. |
2007-04-26 |
2023-08-12 |
rat |
| Blaine E Bisel, Kristen M Henkins, Karen D Parfit. Alzheimer amyloid beta-peptide A-beta25-35 blocks adenylate cyclase-mediated forms of hippocampal long-term potentiation. Annals of the New York Academy of Sciences. vol 1097. 2007-04-25. PMID:17413011. |
alzheimer amyloid beta-peptide a-beta25-35 blocks adenylate cyclase-mediated forms of hippocampal long-term potentiation. |
2007-04-25 |
2023-08-12 |
mouse |
| Reisa Sperlin. Functional MRI studies of associative encoding in normal aging, mild cognitive impairment, and Alzheimer's disease. Annals of the New York Academy of Sciences. vol 1097. 2007-04-25. PMID:17413017. |
our fmri studies, as well as those of several other groups, have consistently demonstrated that, compared to cognitively intact older subjects, patients with clinical alzheimer's disease (ad) have decreased fmri activation in the hippocampus and related structures within the medial temporal lobe during the encoding of new memories. |
2007-04-25 |
2023-08-12 |
human |
| Ana Carolina Pereira, William Wu, Scott A Smal. Imaging-guided microarray: isolating molecular profiles that dissociate Alzheimer's disease from normal aging. Annals of the New York Academy of Sciences. vol 1097. 2007-04-25. PMID:17413025. |
although both alzheimer's disease (ad) and normal aging contribute to age-related hippocampal dysfunction, they are likely governed by separate molecular mechanisms. |
2007-04-25 |
2023-08-12 |
Not clear |
| Paul M Thompson, Kiralee M Hayashi, Rebecca A Dutton, Ming-Chang Chiang, Alex D Leow, Elizabeth R Sowell, Greig De Zubicaray, James T Becker, Oscar L Lopez, Howard J Aizenstein, Arthur W Tog. Tracking Alzheimer's disease. Annals of the New York Academy of Sciences. vol 1097. 2007-04-25. PMID:17413023. |
we describe three novel brain mapping techniques, cortical thickness mapping, tensor-based morphometry (tbm), and hippocampal surface modeling, which offer enormous power for measuring disease progression in drug trials, and shed light on the neuroscience of brain degeneration in alzheimer's disease (ad) and mild cognitive impairment (mci). |
2007-04-25 |
2023-08-12 |
human |
| Craig S McLachlan, Melissa L Chen, Clare N Lynex, Denise L M Goh, Sydney Brenner, Stacey K H Ta. Changes in PDE4D isoforms in the hippocampus of a patient with advanced Alzheimer disease. Archives of neurology. vol 64. issue 3. 2007-04-24. PMID:17353396. |
changes in pde4d isoforms in the hippocampus of a patient with advanced alzheimer disease. |
2007-04-24 |
2023-08-12 |
Not clear |
| Haijia Yu, Jinsong Ren, Xiaogang Q. Time-dependent DNA condensation induced by amyloid beta-peptide. Biophysical journal. vol 92. issue 1. 2007-04-23. PMID:17028131. |
evidence exists for non-b dna conformation in the hippocampus of alzheimer's disease brains, and abeta was reportedly able to transform dna conformation in vitro. |
2007-04-23 |
2023-08-12 |
Not clear |
| Winnie S Liang, Travis Dunckley, Thomas G Beach, Andrew Grover, Diego Mastroeni, Douglas G Walker, Richard J Caselli, Walter A Kukull, Daniel McKeel, John C Morris, Christine Hulette, Donald Schmechel, Gene E Alexander, Eric M Reiman, Joseph Rogers, Dietrich A Stepha. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiological genomics. vol 28. issue 3. 2007-04-19. PMID:17077275. |
these regions, which are also known to be differentially vulnerable to the histopathological and metabolic features of alzheimer's disease (ad), include the entorhinal cortex and hippocampus (limbic and paralimbic areas vulnerable to early neurofibrillary tangle pathology in ad), posterior cingulate cortex (a paralimbic area vulnerable to early metabolic abnormalities in ad), temporal and prefrontal cortex (unimodal and heteromodal sensory association areas vulnerable to early neuritic plaque pathology in ad), and primary visual cortex (a primary sensory area relatively spared in early ad). |
2007-04-19 |
2023-08-12 |
human |