| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susi Zara, Antonio Di Stefano, Cinzia Nasuti, Monica Rapino, Antonia Patruno, Mirko Pesce, Piera Sozio, Laura S Cerasa, Amelia Catald. NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer's disease, in response to a new lipophilic molecular combination codrug-1. Experimental gerontology. vol 46. issue 4. 2011-08-09. PMID:21070848. |
alzheimer's disease is a neurodegenerative pathology due to the presence of β-amyloid plaques at brain level and hippocampus level and associated with the loss of memory speech and learning. |
2011-08-09 |
2023-08-12 |
human |
| Shaomin Li, Ming Jin, Thomas Koeglsperger, Nina E Shepardson, Ganesh M Shankar, Dennis J Selko. Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 18. 2011-08-05. PMID:21543591. |
in alzheimer's disease (ad), dementia severity correlates strongly with decreased synapse density in hippocampus and cortex. |
2011-08-05 |
2023-08-12 |
mouse |
| Xiao-hang Yang, Zhi-bin Liu, Wen-min Niu, Xiao-mei Ni. [Effect of "Xiusanzhen" on hippocampal muscarinic cholinergic receptor activity in Alzheimer disease rats]. Zhen ci yan jiu = Acupuncture research. vol 36. issue 2. 2011-08-04. PMID:21717774. |
[effect of "xiusanzhen" on hippocampal muscarinic cholinergic receptor activity in alzheimer disease rats]. |
2011-08-04 |
2023-08-12 |
rat |
| Xiao-hang Yang, Zhi-bin Liu, Wen-min Niu, Xiao-mei Ni. [Effect of "Xiusanzhen" on hippocampal muscarinic cholinergic receptor activity in Alzheimer disease rats]. Zhen ci yan jiu = Acupuncture research. vol 36. issue 2. 2011-08-04. PMID:21717774. |
to explore the effect of "xiusanzhen" [electroacupuncture (ea) of bilateral "yingxiang" (li 20) and "yintang" (ex-hn 3)] on activities of hippocampal muscarinic cholinergic receptor (machr) and the involved neural path in alzheimer disease(ad)rats. |
2011-08-04 |
2023-08-12 |
rat |
| Wei-guo Xue, Zhong Zhang, Hong Xu, Hai-xia Wu, Li-min Ba. [Effect of electroacupuncture on learning-memory ability, and Abeta and LRP1 immunoactivity in hippocampal sulcus microvessels in APP transgenic mice]. Zhen ci yan jiu = Acupuncture research. vol 36. issue 2. 2011-08-04. PMID:21717775. |
to investigate the effect of electroacupuncture (ea) of "baihui" (gv 20) and "yongquan" (ki 1) on the expression of amyloid beta protein (abeta) and low density lipoprotein (ldl) receptor-related protein 1 (lrp 1) in the hippocampal sulcus microvessels in amyloid precursor protein (app) 695 v717 i transgenic mice, so as to study its mechanism underlying relief of alzheimer disease (ad). |
2011-08-04 |
2023-08-12 |
mouse |
| J A Bermúdez-Lugo, M C Rosales-Hernández, O Deeb, J Trujillo-Ferrara, J Correa-Basurt. In silico methods to assist drug developers in acetylcholinesterase inhibitor design. Current medicinal chemistry. vol 18. issue 8. 2011-08-01. PMID:21291371. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by a low acetylcholine (ach) concentration in the hippocampus and cortex. |
2011-08-01 |
2023-08-12 |
Not clear |
| Sergi G Costafreda, Ivo D Dinov, Zhuowen Tu, Yonggang Shi, Cheng-Yi Liu, Iwona Kloszewska, Patrizia Mecocci, Hilkka Soininen, Magda Tsolaki, Bruno Vellas, Lars-Olof Wahlund, Christian Spenger, Arthur W Toga, Simon Lovestone, Andrew Simmon. Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment. NeuroImage. vol 56. issue 1. 2011-07-29. PMID:21272654. |
the hippocampus is involved at the onset of the neuropathological pathways leading to alzheimer's disease (ad). |
2011-07-29 |
2023-08-12 |
human |
| Jyrki Lötjönen, Robin Wolz, Juha Koikkalainen, Valtteri Julkunen, Lennart Thurfjell, Roger Lundqvist, Gunhild Waldemar, Hilkka Soininen, Daniel Ruecker. Fast and robust extraction of hippocampus from MR images for diagnostics of Alzheimer's disease. NeuroImage. vol 56. issue 1. 2011-07-29. PMID:21281717. |
fast and robust extraction of hippocampus from mr images for diagnostics of alzheimer's disease. |
2011-07-29 |
2023-08-12 |
Not clear |
| April J Ho, Cyrus A Raji, Priya Saharan, Andrew DeGiorgio, Sarah K Madsen, Derrek P Hibar, Jason L Stein, James T Becker, Oscar L Lopez, Arthur W Toga, Paul M Thompso. Hippocampal volume is related to body mass index in Alzheimer's disease. Neuroreport. vol 22. issue 1. 2011-07-28. PMID:21539003. |
hippocampal volume is related to body mass index in alzheimer's disease. |
2011-07-28 |
2023-08-12 |
Not clear |
| April J Ho, Cyrus A Raji, Priya Saharan, Andrew DeGiorgio, Sarah K Madsen, Derrek P Hibar, Jason L Stein, James T Becker, Oscar L Lopez, Arthur W Toga, Paul M Thompso. Hippocampal volume is related to body mass index in Alzheimer's disease. Neuroreport. vol 22. issue 1. 2011-07-28. PMID:21539003. |
obesity is associated with lower brain volumes in early alzheimer's disease, but its effects on hippocampal volumes are unclear, as weight loss is also associated with alzheimer's disease. |
2011-07-28 |
2023-08-12 |
Not clear |
| April J Ho, Cyrus A Raji, Priya Saharan, Andrew DeGiorgio, Sarah K Madsen, Derrek P Hibar, Jason L Stein, James T Becker, Oscar L Lopez, Arthur W Toga, Paul M Thompso. Hippocampal volume is related to body mass index in Alzheimer's disease. Neuroreport. vol 22. issue 1. 2011-07-28. PMID:21539003. |
to address this question, we applied an automated hippocampal mapping method to brain mri scans for 162 patients with alzheimer's disease. |
2011-07-28 |
2023-08-12 |
Not clear |
| Amy D Owen, R David Hayward, Harold G Koenig, David C Steffens, Martha E Payn. Religious factors and hippocampal atrophy in late life. PloS one. vol 6. issue 3. 2011-07-26. PMID:21479219. |
hippocampal volume has been linked to clinical outcomes, such as depression, dementia, and alzheimer's disease. |
2011-07-26 |
2023-08-12 |
human |
| Peter T Nelson, Frederick A Schmitt, Yushun Lin, Erin L Abner, Gregory A Jicha, Ela Patel, Paula C Thomason, Janna H Neltner, Charles D Smith, Karen S Santacruz, Joshua A Sonnen, Leonard W Poon, Marla Gearing, Robert C Green, John L Woodard, Linda J Van Eldik, Richard J Krysci. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain : a journal of neurology. vol 134. issue Pt 5. 2011-07-22. PMID:21596774. |
hippocampal sclerosis is a relatively common neuropathological finding (∼10% of individuals over the age of 85 years) characterized by cell loss and gliosis in the hippocampus that is not explained by alzheimer's disease. |
2011-07-22 |
2023-08-12 |
Not clear |
| Peter T Nelson, Frederick A Schmitt, Yushun Lin, Erin L Abner, Gregory A Jicha, Ela Patel, Paula C Thomason, Janna H Neltner, Charles D Smith, Karen S Santacruz, Joshua A Sonnen, Leonard W Poon, Marla Gearing, Robert C Green, John L Woodard, Linda J Van Eldik, Richard J Krysci. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain : a journal of neurology. vol 134. issue Pt 5. 2011-07-22. PMID:21596774. |
for individuals aged≥95 years at death (n=179 in our sample), each year of life beyond the age of 95 years correlated with increased prevalence of hippocampal sclerosis pathology and decreased prevalence of 'definite' alzheimer's disease pathology. |
2011-07-22 |
2023-08-12 |
Not clear |
| Peter T Nelson, Frederick A Schmitt, Yushun Lin, Erin L Abner, Gregory A Jicha, Ela Patel, Paula C Thomason, Janna H Neltner, Charles D Smith, Karen S Santacruz, Joshua A Sonnen, Leonard W Poon, Marla Gearing, Robert C Green, John L Woodard, Linda J Van Eldik, Richard J Krysci. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain : a journal of neurology. vol 134. issue Pt 5. 2011-07-22. PMID:21596774. |
this may provide a first step in clinical differentiation of hippocampal sclerosis associated with ageing versus pure alzheimer's disease in their earliest stages. |
2011-07-22 |
2023-08-12 |
Not clear |
| Andrew E Barry, Igor Klyubin, Jessica M Mc Donald, Alexandra J Mably, Michael A Farrell, Michael Scott, Dominic M Walsh, Michael J Rowa. Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 20. 2011-07-21. PMID:21593310. |
here we report that intracerebroventricular injection of aβ-containing aqueous extracts of alzheimer's disease (ad) brain robustly inhibits long-term potentiation (ltp) without significantly affecting baseline excitatory synaptic transmission in the rat hippocampus in vivo. |
2011-07-21 |
2023-08-12 |
rat |
| P Friedrich, T M Feulner, S M Laws, K Eckart, R Perneczky, A Kurz, H Förstl, M Riemenschneide. No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease. Neurobiology of aging. vol 32. issue 3. 2011-07-19. PMID:19375820. |
functionally, the tacr2 has been implicated in stress induced hippocampal acetylcholine release and the gene tacr2 is located within a previously identified linkage region for alzheimer's disease (ad) on chromosome 10q21. |
2011-07-19 |
2023-08-12 |
human |
| Fu-Qian He, Bo-Yun Qiu, Xiao-Hui Zhang, Tian-Ke Li, Qin Xie, De-Jun Cui, Xiao-Li Huang, Hua-Tian Ga. Tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting NF-κB activation in a rat model of Alzheimer's disease induced by amyloid-β(1-42). Brain research. vol 1384. 2011-07-19. PMID:21300035. |
tetrandrine attenuates spatial memory impairment and hippocampal neuroinflammation via inhibiting nf-κb activation in a rat model of alzheimer's disease induced by amyloid-β(1-42). |
2011-07-19 |
2023-08-12 |
rat |
| Sachin Patil, Deebika Balu, Joseph Melrose, Christina Cha. Brain region-specificity of palmitic acid-induced abnormalities associated with Alzheimer's disease. BMC research notes. vol 1. 2011-07-14. PMID:18710535. |
alzheimer's disease (ad) is a progressive, neurodegenerative disease mostly affecting the basal forebrain, cortex and hippocampus whereas the cerebellum is relatively spared. |
2011-07-14 |
2023-08-12 |
Not clear |
| P Calissano, C Matrone, G Amador. Apoptosis and in vitro Alzheimer disease neuronal models. Communicative & integrative biology. vol 2. issue 2. 2011-07-14. PMID:19513272. |
alzheimer disease (ad) is a human neurodegenerative disease characterized by co-existence of extracellular senile plaques (sp) and neurofibrillary tangles (nft) associated with an extensive neuronal loss, primarily in the cerebral cortex and hippocampus. |
2011-07-14 |
2023-08-12 |
human |