| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alice Palmer, Mark Goo. Hippocampal synaptic activity, pattern separation and episodic-like memory: implications for mouse models of Alzheimer's disease pathology. Biochemical Society transactions. vol 39. issue 4. 2011-11-15. PMID:21787321. |
hippocampal synaptic activity, pattern separation and episodic-like memory: implications for mouse models of alzheimer's disease pathology. |
2011-11-15 |
2023-08-12 |
mouse |
| Pierrick Coupé, Simon F Eskildsen, José V Manjón, Vladimir Fonov, D Louis Collin. Simultaneous segmentation and grading of hippocampus for patient classification with Alzheimer's disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 14. issue Pt 3. 2011-11-15. PMID:22013614. |
simultaneous segmentation and grading of hippocampus for patient classification with alzheimer's disease. |
2011-11-15 |
2023-08-12 |
Not clear |
| Pierrick Coupé, Simon F Eskildsen, José V Manjón, Vladimir Fonov, D Louis Collin. Simultaneous segmentation and grading of hippocampus for patient classification with Alzheimer's disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 14. issue Pt 3. 2011-11-15. PMID:22013614. |
to propose an innovative approach to better detect alzheimer's disease (ad) based on a finer detection of hippocampus (hc) atrophy patterns. |
2011-11-15 |
2023-08-12 |
Not clear |
| Ulises M Ricoy, Peizhong Mao, Maria Manczak, P Hemachandra Reddy, Matthew E Frerkin. A transgenic mouse model for Alzheimer's disease has impaired synaptic gain but normal synaptic dynamics. Neuroscience letters. vol 500. issue 3. 2011-11-14. PMID:21741442. |
the chronic accumulation of amyloid beta (aβ) peptides is thought to underlie much of the pathology of alzheimer's disease (ad), and transgenic mice overexpressing aβ show both behavioral defects and impairments in hippocampal synaptic transmission. |
2011-11-14 |
2023-08-12 |
mouse |
| D V Moretti, A Prestia, C Fracassi, C Geroldi, G Binetti, P M Rossini, O Zanetti, G B Frison. Volumetric differences in mapped hippocampal regions correlate with increase of high alpha rhythm in Alzheimer's disease. International journal of Alzheimer's disease. vol 2011. 2011-11-10. PMID:21760984. |
volumetric differences in mapped hippocampal regions correlate with increase of high alpha rhythm in alzheimer's disease. |
2011-11-10 |
2023-08-12 |
human |
| D V Moretti, A Prestia, C Fracassi, C Geroldi, G Binetti, P M Rossini, O Zanetti, G B Frison. Volumetric differences in mapped hippocampal regions correlate with increase of high alpha rhythm in Alzheimer's disease. International journal of Alzheimer's disease. vol 2011. 2011-11-10. PMID:21760984. |
the increase of high alpha relative to low alpha power has been recently demonstrated as a reliable eeg marker of hippocampal atrophy conversion of patients with mild cognitive impairment (mci) in alzheimer's disease (ad). |
2011-11-10 |
2023-08-12 |
human |
| D V Moretti, A Prestia, C Fracassi, C Geroldi, G Binetti, P M Rossini, O Zanetti, G B Frison. Volumetric differences in mapped hippocampal regions correlate with increase of high alpha rhythm in Alzheimer's disease. International journal of Alzheimer's disease. vol 2011. 2011-11-10. PMID:21760984. |
results show that the increase of alpha3/alpha2 power ratio is correlated with atrophy of mapped hippocampal regions in alzheimer's disease. |
2011-11-10 |
2023-08-12 |
human |
| F Palesi, P Vitali, P Chiarati, G Castellazzi, E Caverzasi, A Pichiecchio, E Colli-Tibaldi, F D'Amore, I D'Errico, E Sinforiani, S Bastianell. DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease. Neurology research international. vol 2012. 2011-11-10. PMID:21773026. |
hippocampal damage, by dti or mr volumetry, and pet hypoperfusion of precuneus/posterior cingulate cortex (pc/pcc) were proposed as biomarkers of conversion from preclinical (mci) to clinical stage of alzheimer's disease (ad). |
2011-11-10 |
2023-08-12 |
Not clear |
| Markel Olabarria, Harun N Noristani, Alexei Verkhratsky, José J Rodrígue. Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission? Molecular neurodegeneration. vol 6. 2011-11-10. PMID:21801442. |
age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission? |
2011-11-10 |
2023-08-12 |
mouse |
| Subbiah Pugazhenthi, Maorong Wang, Serena Pham, Chun-I Sze, Christopher B Eckma. Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons. Molecular neurodegeneration. vol 6. 2011-11-10. PMID:21854604. |
downregulation of creb expression in alzheimer's brain and in aβ-treated rat hippocampal neurons. |
2011-11-10 |
2023-08-12 |
mouse |
| Michael Ewers, Xin Cheng, Zhenyu Zhong, Hikmet F Nural, Cathal Walsh, Thomas Meindl, Stefan J Teipel, Katharina Buerger, Ping He, Yong Shen, Harald Hampe. Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 25. issue 2. 2011-11-04. PMID:21460439. |
increased csf-bace1 activity associated with decreased hippocampus volume in alzheimer's disease. |
2011-11-04 |
2023-08-12 |
Not clear |
| Kara G Pratt, Eric C Zimmerman, David G Cook, Jane M Sulliva. Presenilin 1 regulates homeostatic synaptic scaling through Akt signaling. Nature neuroscience. vol 14. issue 9. 2011-10-24. PMID:21841774. |
we found that homeostatic scaling of excitatory synapses was impaired in hippocampal neurons derived from mice lacking presenilin 1 (psen1(-/-) mice) or expressing a familial alzheimer's disease-linked psen1 mutation (psen1(m146v)). |
2011-10-24 |
2023-08-12 |
mouse |
| Ignacio Lopez-Coviella, Tiffany J Mellott, Aletta C Schnitzler, Jan K Blusztaj. BMP9 protects septal neurons from axotomy-evoked loss of cholinergic phenotype. PloS one. vol 6. issue 6. 2011-10-21. PMID:21695154. |
cholinergic projection from the septum to the hippocampus is crucial for normal cognitive function and degeneration of cells and nerve fibers within the septohippocampal pathway contributes to the pathophysiology of alzheimer's disease. |
2011-10-21 |
2023-08-12 |
Not clear |
| Yalin Wang, Yang Song, Priya Rajagopalan, Tuo An, Krystal Liu, Yi-Yu Chou, Boris Gutman, Arthur W Toga, Paul M Thompso. Surface-based TBM boosts power to detect disease effects on the brain: an N=804 ADNI study. NeuroImage. vol 56. issue 4. 2011-10-17. PMID:21440071. |
in alzheimer's disease (ad), many research groups have modeled localized changes in hippocampal and lateral ventricular surfaces, to provide candidate biomarkers of disease progression for drug trials. |
2011-10-17 |
2023-08-12 |
human |
| Yalin Wang, Yang Song, Priya Rajagopalan, Tuo An, Krystal Liu, Yi-Yu Chou, Boris Gutman, Arthur W Toga, Paul M Thompso. Surface-based TBM boosts power to detect disease effects on the brain: an N=804 ADNI study. NeuroImage. vol 56. issue 4. 2011-10-17. PMID:21440071. |
we combined the power of parametric surface modeling and tensor-based morphometry to study hippocampal differences associated with ad and mild cognitive impairment (mci) in 490 subjects (97 ad, 245 mci, 148 controls) and ventricular differences in 804 subjects scanned as part of the alzheimer's disease neuroimaging initiative (adni; 184 ad, 391 mci, 229 controls). |
2011-10-17 |
2023-08-12 |
human |
| Enrico Cherubini, Marilena Griguoli, Victoria Safiulina, Laura Lagosten. The depolarizing action of GABA controls early network activity in the developing hippocampus. Molecular neurobiology. vol 43. issue 2. 2011-10-14. PMID:21042953. |
evidence has been recently provided that in chronically nerve growth factor-deprived mice expressing a progressive age-dependent neurodegenerative pathology resembling that observed in patients with alzheimer's disease, the reduced expression of mrna encoding for the kcc2 gene and the depolarizing action of gaba lead to the reorganization of the neuronal hippocampal network. |
2011-10-14 |
2023-08-12 |
mouse |
| Mert R Sabuncu, Rahul S Desikan, Jorge Sepulcre, Boon Thye T Yeo, Hesheng Liu, Nicholas J Schmansky, Martin Reuter, Michael W Weiner, Randy L Buckner, Reisa A Sperling, Bruce Fisch. The dynamics of cortical and hippocampal atrophy in Alzheimer disease. Archives of neurology. vol 68. issue 8. 2011-10-13. PMID:21825241. |
the dynamics of cortical and hippocampal atrophy in alzheimer disease. |
2011-10-13 |
2023-08-12 |
Not clear |
| Leila Hejazi, Jason W H Wong, Danni Cheng, Nicholas Proschogo, Diako Ebrahimi, Brett Garner, Anthony S Do. Mass and relative elution time profiling: two-dimensional analysis of sphingolipids in Alzheimer's disease brains. The Biochemical journal. vol 438. issue 1. 2011-10-06. PMID:21639855. |
we describe a new approach, involving lc×ms/ms (liquid chromatography×tandem ms) analysis of sphingolipids based on both mass and hydrophobicity, and use this method to characterize the sm (sphingomyelin), ceramide and galcer (galactosylceramide) content of hippocampus from ad (alzheimer's disease) and control subjects. |
2011-10-06 |
2023-08-12 |
human |
| Mitra Ameli, Friederike Kemper, Anna-Sophia Sarfeld, Josef Kessler, Gereon R Fink, Dennis A Nowa. Arbitrary visuo-motor mapping during object manipulation in mild cognitive impairment and Alzheimer's disease: a pilot study. Clinical neurology and neurosurgery. vol 113. issue 6. 2011-09-30. PMID:21353384. |
empirical evidence for an essential role of the hippocampal system in arbitrary visuo-motor mapping suggests that acquisition and retrieval of arbitrary visuo-motor mapping might be impaired in mild cognitive impairment (mci) and alzheimer's disease (ad). |
2011-09-30 |
2023-08-12 |
Not clear |
| Sridhar Krishnamurti, Lyle Drake, Justin Kin. Neural network modeling of central auditory dysfunction in Alzheimer's disease. Neural networks : the official journal of the International Neural Network Society. vol 24. issue 6. 2011-09-30. PMID:21441013. |
many reports have described that individuals with alzheimer's disease show neural breakdown in the brainstem nuclei, hippocampus and auditory cortex in the temporal lobe of the brain. |
2011-09-30 |
2023-08-12 |
Not clear |