| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fabio Di Domenico, Rukhsana Sultana, Eugenio Barone, Marzia Perluigi, Chiara Cini, Cesare Mancuso, Jian Cai, William M Pierce, D Allan Butterfiel. Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects. Journal of proteomics. vol 74. issue 7. 2011-09-26. PMID:21515431. |
quantitative proteomics analysis of phosphorylated proteins in the hippocampus of alzheimer's disease subjects. |
2011-09-26 |
2023-08-12 |
human |
| Xin Liu, Yi-na Zhang, Zong-yan Teng, Li-hong Jian. [Abnormal expression of insulin receptor induced by Aβ(1-42) in rat hippocampus neuron]. Zhonghua yi xue za zhi. vol 90. issue 41. 2011-09-15. PMID:21211393. |
to detect the expression change of insulin receptor under the induction of aβ(1-42) in rat hippocampus neuron and thus from the receptor level explore the disorder of central nervous insulin signaling and molecular mechanism of alzheimer's disease. |
2011-09-15 |
2023-08-12 |
rat |
| Yasuhiro Kawamoto, Hidefumi Ito, Yoshito Kobayashi, Yasuyuki Suzuki, Ryosuke Takahash. Localization of HtrA2/Omi immunoreactivity in brains affected by Alzheimer's disease. Neuroreport. vol 21. issue 17. 2011-09-13. PMID:20938363. |
in the cerebral cortex and hippocampus from the cases of alzheimer's disease, densely accumulated htra2/omi immunoreactivity was scattered, both intracellularly and extracellularly. |
2011-09-13 |
2023-08-12 |
Not clear |
| Abderazzak Mouiha, Simon Duchesn. Hippocampal atrophy rates in Alzheimer's disease: automated segmentation variability analysis. Neuroscience letters. vol 495. issue 1. 2011-09-13. PMID:21371528. |
hippocampal atrophy rates in alzheimer's disease: automated segmentation variability analysis. |
2011-09-13 |
2023-08-12 |
Not clear |
| Abderazzak Mouiha, Simon Duchesn. Hippocampal atrophy rates in Alzheimer's disease: automated segmentation variability analysis. Neuroscience letters. vol 495. issue 1. 2011-09-13. PMID:21371528. |
hippocampal (hc) atrophy and atrophy rates are putative clinical markers of progression to alzheimer's disease (ad). |
2011-09-13 |
2023-08-12 |
Not clear |
| Mario A Parra, Sergio Della Sala, Sharon Abrahams, Robert H Logie, Luis Guillermo Méndez, Francisco Loper. Specific deficit of colour-colour short-term memory binding in sporadic and familial Alzheimer's disease. Neuropsychologia. vol 49. issue 7. 2011-09-13. PMID:21435348. |
performance on the bound colours condition (1) explained the largest proportion of variance between patients (sporadic and familial alzheimer's disease), (2) combined more sensitivity and specificity for the disease than other more traditional neuropsychological tasks, (3) identified asymptomatic carriers of the mutation even when traditional neuropsychological measures and other measures of short-term memory did not and, (4) contrary to shape-colour binding, correlated with measures of hippocampal functions. |
2011-09-13 |
2023-08-12 |
Not clear |
| Mischa de Rover, Valentino A Pironti, Jonathan A McCabe, Julio Acosta-Cabronero, F Sergio Arana, Sharon Morein-Zamir, John R Hodges, Trevor W Robbins, Paul C Fletcher, Peter J Nestor, Barbara J Sahakia. Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task. Neuropsychologia. vol 49. issue 7. 2011-09-13. PMID:21477602. |
we focused on changes in bold response in the hippocampus and related structures, as an a priori region of interest based on what is known about the neuropathology of the early stages of alzheimer's disease and previous information on the neural substrates of the pal task. |
2011-09-13 |
2023-08-12 |
human |
| Qingli Shi, Gary E Gibso. Up-regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR-743a. Journal of neurochemistry. vol 118. issue 3. 2011-09-13. PMID:21623795. |
oxidative stress, an early and pervasive event in alzheimer's disease, increased mdh activity and mrna level of mdh2 by 19% and 22%, respectively, in a mouse hippocampal cell line (ht22). |
2011-09-13 |
2023-08-12 |
mouse |
| Shubham Misra, Vinod Tiwari, Anurag Kuhad, Kanwaljit Chopr. Modulation of nitrergic pathway by sesamol prevents cognitive deficits and associated biochemical alterations in intracerebroventricular streptozotocin administered rats. European journal of pharmacology. vol 659. issue 2-3. 2011-09-09. PMID:21463622. |
alzheimer's disease is a neurodegenerative disorder characterized by progressive cognitive decline and widespread loss of neurons and their synapses in the cerebral cortex and hippocampus. |
2011-09-09 |
2023-08-12 |
rat |
| Johannes Attems, Arne Ittner, Kurt Jellinger, Roger M Nitsch, Magdalena Maj, Ludwig Wagner, Jürgen Götz, Mathias Heikenwalde. Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice. Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 5. 2011-09-08. PMID:21442354. |
neuropathological features in alzheimer's disease (ad) include the presence of hyperphosphorylated forms of the microtubule-associated tau protein (tau) in hippocampal neurones. |
2011-09-08 |
2023-08-12 |
mouse |
| Daniel Varon, David A Loewenstein, Elizabeth Potter, Maria T Greig, Joscelyn Agron, Qian Shen, Weizhao Zhao, Maria Celeste Ramirez, Isael Santos, Warren Barker, Huntington Potter, Ranjan Duar. Minimal atrophy of the entorhinal cortex and hippocampus: progression of cognitive impairment. Dementia and geriatric cognitive disorders. vol 31. issue 4. 2011-09-01. PMID:21494034. |
in alzheimer's disease, neurodegenerative atrophy progresses from the entorhinal cortex (erc) to the hippocampus (hp), limbic system and neocortex. |
2011-09-01 |
2023-08-12 |
human |
| Marie Sarazin, Valérie Chauviré, Emilie Gerardin, Olivier Colliot, Serge Kinkingnéhun, Leonardo Cruz de Souza, Laurence Hugonot-Diener, Line Garnero, Stéphane Lehéricy, Marie Chupin, Bruno Duboi. The amnestic syndrome of hippocampal type in Alzheimer's disease: an MRI study. Journal of Alzheimer's disease : JAD. vol 22. issue 1. 2011-08-29. PMID:20847406. |
the amnestic syndrome of hippocampal type in alzheimer's disease: an mri study. |
2011-08-29 |
2023-08-12 |
Not clear |
| Dale E Bredesen, Varghese John, Veronica Galva. Importance of the caspase cleavage site in amyloid-β protein precursor. Journal of Alzheimer's disease : JAD. vol 22. issue 1. 2011-08-29. PMID:20847422. |
reports from multiple laboratories have now been published analyzing the critical nature of the caspase cleavage site of amyloid-β protein precursor (aβpp) for cell death induction, synaptic loss, hippocampal atrophy, long-term potentiation, memory loss, neophobia, and other aspects of the alzheimer's phenotype. |
2011-08-29 |
2023-08-12 |
Not clear |
| Ying Cao, Yan Xiao, Rivka Ravid, Zhi-Zhong Gua. Changed clathrin regulatory proteins in the brains of Alzheimer's disease patients and animal models. Journal of Alzheimer's disease : JAD. vol 22. issue 1. 2011-08-29. PMID:20847448. |
in the study, the expression of clathrin regulatory proteins dynamin i, ap180, and synaptic vesicle protein synaptophysin in multiple brain regions of the patients with alzheimer's disease (ad), the transgenic mice carrying the swedish mutation of amyloid-β protein precursor (aβpp) 670/671 (aβppswe), and the rats injected by bilateral hippocampus with amyloid-β peptide (aβ)1-42 were examined by immunohistochemistry and nissl staining, western blotting, and real-time pcr, respectively. |
2011-08-29 |
2023-08-12 |
mouse |
| Ernst Niedermeyer, Janet O Ghig. Alzheimer dementia: an overview and a promising new concept. American journal of electroneurodiagnostic technology. vol 51. issue 2. 2011-08-25. PMID:21809745. |
in it en provides evidence that in true alzheimer dementia (ad), memory loss is the initially dominating problem due to deterioration of the circulation in the hippocampus, which has a vulnerable blood supply to begin with. |
2011-08-25 |
2023-08-12 |
Not clear |
| Taiki Kambe, Yumiko Motoi, Ran Inoue, Nobuhiko Kojima, Norihiro Tada, Tetsuya Kimura, Naruhiko Sahara, Shunji Yamashita, Tatsuya Mizoroki, Akihiko Takashima, Kohei Shimada, Koichi Ishiguro, Hiroshi Mizuma, Hirotaka Onoe, Yoshikuni Mizuno, Nobutaka Hattor. Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice. Neurobiology of disease. vol 42. issue 3. 2011-08-23. PMID:21324362. |
in alzheimer's disease, basal forebrain and hippocampus are mainly involved, while frontotemporal lobar degeneration affects the frontal and temporal lobes and subcortical nuclei including striatum. |
2011-08-23 |
2023-08-12 |
mouse |
| Baozhi Gang, Cen Yue, Na Han, Hongjuan Xue, Baoxin Li, Lihua Sun, Xuelian Li, Qingjie Zha. Limited hippocampal neurogenesis in SAMP8 mouse model of Alzheimer's disease. Brain research. vol 1389. 2011-08-23. PMID:21439270. |
limited hippocampal neurogenesis in samp8 mouse model of alzheimer's disease. |
2011-08-23 |
2023-08-12 |
mouse |
| R Rupsingh, M Borrie, M Smith, J L Wells, R Barth. Reduced hippocampal glutamate in Alzheimer disease. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19501936. |
reduced hippocampal glutamate in alzheimer disease. |
2011-08-17 |
2023-08-12 |
human |
| Elvan Ceyhan, Mirza Faisal Beg, Can Ceritoglu, Lei Wang, John C Morris, John G Csernansky, Michael I Miller, J Tilak Ratnanathe. Quantization and analysis of hippocampal morphometric changes due to dementia of Alzheimer type using metric distances based on large deformation diffeomorphic metric mapping. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. vol 35. issue 4. 2011-08-11. PMID:21345652. |
quantization and analysis of hippocampal morphometric changes due to dementia of alzheimer type using metric distances based on large deformation diffeomorphic metric mapping. |
2011-08-11 |
2023-08-12 |
Not clear |
| Elvan Ceyhan, Mirza Faisal Beg, Can Ceritoglu, Lei Wang, John C Morris, John G Csernansky, Michael I Miller, J Tilak Ratnanathe. Quantization and analysis of hippocampal morphometric changes due to dementia of Alzheimer type using metric distances based on large deformation diffeomorphic metric mapping. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society. vol 35. issue 4. 2011-08-11. PMID:21345652. |
for illustrative purposes we consider changes in hippocampal morphometry (shape and size) due to very mild dementia of the alzheimer type (dat). |
2011-08-11 |
2023-08-12 |
Not clear |