| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samira A Maboudian, Ethan H Willbrand, William J Jagust, Kevin S Weine. Defining overlooked structures reveals new associations between cortex and cognition in aging and Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425904. |
recent work suggests that indentations of the cerebral cortex, or sulci, may be uniquely vulnerable to atrophy in aging and alzheimer's disease (ad) and that posteromedial cortex (pmc) is particularly vulnerable to atrophy and pathology accumulation. |
2023-07-10 |
2023-08-14 |
human |
| Angelo Arleo, Martin Bareš, Jessica A Bernard, Hannah R Bogoian, Muriel M K Bruchhage, Patrick Bryant, Erik S Carlson, Chetwyn C H Chan, Liang-Kung Chen, Chih-Ping Chung, Vonetta M Dotson, Pavel Filip, Xavier Guell, Christophe Habas, Heidi I L Jacobs, Shinji Kakei, Tatia M C Lee, Maria Leggio, Maria Misiura, Hiroshi Mitoma, Giusy Olivito, Stephen Ramanoël, Zeynab Rezaee, Colby L Samstag, Jeremy D Schmahmann, Kaoru Sekiyama, Clive H Y Wong, Masatoshi Yamashita, Mario Mant. Consensus Paper: Cerebellum and Ageing. Cerebellum (London, England). 2023-07-10. PMID:37428408. |
neuroimaging studies highlight that the cerebellum might be involved in the cognitive decline occurring in alzheimer's disease (ad), independently of contributions of the cerebral cortex. |
2023-07-10 |
2023-08-14 |
human |
| Lingxuan Chen, Zoé Christenson Wick, Lauren M Vetere, Nick Vaughan, Albert Jurkowski, Angelina Galas, Keziah S Diego, Paul Philipsberg, Denise J Cai, Tristan Shuma. Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer's disease pathology. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37398359. |
progressive excitability changes in the medial entorhinal cortex in the 3xtg mouse model of alzheimer's disease pathology. |
2023-07-03 |
2023-08-14 |
mouse |
| Vahid Gazestani, Tushar Kamath, Naeem M Nadaf, S J Burris, Brendan Rooney, Antti Junkkari, Charles Vanderburg, Tuomas Rauramaa, Martine Therrien, Matthew Tegtmeyer, Sanna-Kaisa Herukka, Abdulraouf Abdulraouf, Samuel Marsh, Tarja Malm, Mikko Hiltunen, Ralda Nehme, Beth Stevens, Ville Leinonen, Evan Z Macosk. Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333365. |
early alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. |
2023-06-19 |
2023-08-14 |
human |
| Anika Wuestefeld, Hannah Baumeister, Jenna N Adams, Robin de Flores, Carl Hodgetts, Negar Mazloum-Farzaghi, Rosanna K Olsen, Vyash Puliyadi, Tammy T Tran, Arnold Bakker, Kelsey L Canada, Marshall A Dalton, Ana M Daugherty, Renaud La Joie, Lei Wang, Madigan Bedard, Esther Buendia, Amanda Denning, David J Irwin, Ranjit Ittyerah, Edward B Lee, Sydney Lim, Maria Mercedes Iñiguez de Onzoño Martin, Monica Munoz Lopez, Theresa Schuck, Winifred Trotman, Alicia Vela, Paul Yushkevich, Katrin Amunts, Jean C Augustinack, Song-Lin Ding, Ricardo Insausti, Olga Kedo, David Berron, Laura E M Wiss. Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292729. |
the medial temporal lobe (mtl) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as alzheimer's disease neurofibrillary tau tangles. |
2023-06-09 |
2023-08-14 |
human |
| Chiara Falcicchia, Francesca Tozzi, Martina Gabrielli, Stefano Amoretti, Greta Masini, Gabriele Nardi, Stefano Guglielmo, Gian Michele Ratto, Ottavio Arancio, Claudia Verderio, Nicola Origli. Microglial extracellular vesicles induce Alzheimer's disease-related cortico-hippocampal network dysfunction. Brain communications. vol 5. issue 3. 2023-06-08. PMID:37288314. |
here, using chronic eeg recordings, we show that a single injection of extracellular vesicles carrying β-amyloid into the mouse entorhinal cortex could trigger alterations in the cortical and hippocampal activity that are reminiscent of those found in alzheimer's disease mouse models and human patients. |
2023-06-08 |
2023-08-14 |
mouse |
| ZiJie Liu, Qing Xia, Xue Zhao, FeiFei Zheng, JiaYing Xiao, FangLiang Ge, DaYong Wang, Xu Ga. The Landscape of m6A Regulators in Multiple Brain Regions of Alzheimer's Disease. Molecular neurobiology. 2023-06-05. PMID:37273154. |
our work evaluated the alteration profile of m6a regulators and their influences on alzheimer's disease in 4 brain regions: the postcentral gyrus, superior frontal gyrus, hippocampus, and entorhinal cortex. |
2023-06-05 |
2023-08-14 |
Not clear |
| Jens D Mikkelsen, Sif Kaad, Sanjay S Aripaka, Bente Finse. Synaptic vesicle glycoprotein 2A (SV2A) levels in the cerebral cortex in patients with Alzheimer's disease: a radioligand binding study in postmortem brains. Neurobiology of aging. vol 129. 2023-06-03. PMID:37269646. |
synaptic vesicle glycoprotein 2a (sv2a) levels in the cerebral cortex in patients with alzheimer's disease: a radioligand binding study in postmortem brains. |
2023-06-03 |
2023-08-14 |
Not clear |
| Jens D Mikkelsen, Sif Kaad, Sanjay S Aripaka, Bente Finse. Synaptic vesicle glycoprotein 2A (SV2A) levels in the cerebral cortex in patients with Alzheimer's disease: a radioligand binding study in postmortem brains. Neurobiology of aging. vol 129. 2023-06-03. PMID:37269646. |
histological and biochemical analyses in postmortem tissues have demonstrated neurodegenerative changes in the cerebral cortex in patients with alzheimer's disease (ad), and it has been suggested that this represents a loss of synapses. |
2023-06-03 |
2023-08-14 |
Not clear |
| Kaiyin Cui, Chaoyang Li, Guoliang Fan. Aerobic Exercise Delays Alzheimer's Disease by Regulating Mitochondrial Proteostasis in the Cerebral Cortex and Hippocampus. Life (Basel, Switzerland). vol 13. issue 5. 2023-05-27. PMID:37240849. |
aerobic exercise delays alzheimer's disease by regulating mitochondrial proteostasis in the cerebral cortex and hippocampus. |
2023-05-27 |
2023-08-14 |
mouse |
| Johnson Ying, Antonio Reboreda, Motoharu Yoshida, Mark P Brando. Grid cell disruption in a mouse model of early Alzheimer's disease reflects reduced integration of self-motion cues. Current biology : CB. 2023-05-23. PMID:37220744. |
converging evidence from human and rodent studies suggests that disrupted grid cell coding in the medial entorhinal cortex (mec) underlies path integration behavioral deficits during early alzheimer's disease (ad). |
2023-05-23 |
2023-08-14 |
mouse |
| Elia Obis, Joaquim Sol, Pol Andres-Benito, Meritxell Martín-Gari, Natàlia Mota-Martorell, José Daniel Galo-Licona, Gerard Piñol-Ripoll, Manuel Portero-Otin, Isidro Ferrer, Mariona Jové, Reinald Pamplon. Lipidomic Alterations in the Cerebral Cortex and White Matter in Sporadic Alzheimer's Disease. Aging and disease. 2023-05-17. PMID:37196109. |
lipidomic alterations in the cerebral cortex and white matter in sporadic alzheimer's disease. |
2023-05-17 |
2023-08-14 |
human |
| b' Lea Langer Horvat, Ena \\xc5\\xa0pani\\xc4\\x87 Popova\\xc4\\x8dki, Mirjana Babi\\xc4\\x87 Leko, Klara Zub\\xc4\\x8di\\xc4\\x87, Luka Horvat, Maja Mustapi\\xc4\\x87, Patrick R Hof, Goran \\xc5\\xa0imi\\xc4\\x8. Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model. Biomedicines. vol 11. issue 4. 2023-05-16. PMID:37189622.' |
the tauopathy of alzheimer's disease (ad) is first observed in the brainstem and entorhinal cortex, spreading trans-synaptically along specific pathways to other brain regions with recognizable patterns. |
2023-05-16 |
2023-08-14 |
mouse |
| Seyed Mostafa Hosseinpour Mashkani, David P Bishop, Newsha Raoufi-Rad, Paul A Adlard, Olga Shimoni, S Mojtaba Golza. Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer's Disease. Cells. vol 12. issue 8. 2023-05-16. PMID:37190053. |
distribution of copper, iron, and zinc in the retina, hippocampus, and cortex of the transgenic app/ps1 mouse model of alzheimer's disease. |
2023-05-16 |
2023-08-14 |
mouse |
| Yasmine Sommerer, Valerija Dobricic, Marcel Schilling, Olena Ohlei, Sanaz Sedghpour Sabet, Tanja Wesse, Janina Fuß, Sören Franzenburg, Andre Franke, Laura Parkkinen, Christina M Lill, Lars Bertra. Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer's disease. Alzheimer's research & therapy. vol 15. issue 1. 2023-05-06. PMID:37149695. |
entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in alzheimer's disease. |
2023-05-06 |
2023-08-14 |
Not clear |
| Seyed Hani Hojjati, Tracy A Butler, Gloria C Chiang, Christian Habeck, Arindam RoyChoudhury, Farnia Feiz, Jacob Shteingart, Siddharth Nayak, Sindy Ozoria, Antonio Fernández, Yaakov Stern, José A Luchsinger, Davangere P Devanand, Qolamreza R Razligh. Distinct and joint effects of low and high levels of Aβ and tau deposition on cortical thickness. NeuroImage. Clinical. vol 38. 2023-04-27. PMID:37104927. |
alzheimer's disease (ad) is defined by the presence of amyloid-β (aβ),tau, and neurodegeneration (atn framework) in the human cerebral cortex. |
2023-04-27 |
2023-08-14 |
human |
| Asgeir Kobro-Flatmoen, Claudia Battistin, Rajeevkumar Raveendran Nair, Christiana Bjorkli, Belma Skender, Cliff Kentros, Gunnar Gouras, Menno P Witte. Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β. Brain communications. vol 5. issue 2. 2023-04-24. PMID:37091586. |
projection neurons in the anteriolateral part of entorhinal cortex layer ii are the predominant cortical site for hyper-phosphorylation of tau and formation of neurofibrillary tangles in prodromal alzheimer's disease. |
2023-04-24 |
2023-08-14 |
rat |
| Liting Han, Hanni Jiang, Xufeng Yao, Zhe Ren, Zhongsen Qu, Tonggang Yu, Shichang Luo, Tao W. Revealing the correlations between brain cortical characteristics and susceptibility genes for Alzheimer disease: a cross-sectional study. Quantitative imaging in medicine and surgery. vol 13. issue 4. 2023-04-17. PMID:37064375. |
alzheimer disease (ad) is a progressive neurodegenerative disease closely related to genes and characterized by the atrophy of the cerebral cortex. |
2023-04-17 |
2023-08-14 |
human |
| Robin de Flores, Solène Demeilliez-Servouin, Elizabeth Kuhn, Léa Chauveau, Brigitte Landeau, Nicolas Delcroix, Julie Gonneaud, Denis Vivien, Gaël Chétela. Respective influence of beta-amyloid and APOE ε4 genotype on medial temporal lobe subregions in cognitively unimpaired older adults. Neurobiology of disease. 2023-04-15. PMID:37061167. |
medial temporal lobe (mtl) subregions are differentially affected in alzheimer's disease (ad), with a specific involvement of the entorhinal cortex (erc), perirhinal cortex and hippocampal cornu ammonis (ca)1. |
2023-04-15 |
2023-08-14 |
human |
| Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex and decreases with Alzheimer's Disease progression. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034733. |
basal forebrain activity predicts functional degeneration in the entorhinal cortex and decreases with alzheimer's disease progression. |
2023-04-10 |
2023-08-14 |
Not clear |