| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giulia Quattrini, Lorenzo Pini, Ilaria Boscolo Galazzo, Ileana O Jelescu, Jorge Jovicich, Rosa Manenti, Giovanni B Frisoni, Moira Marizzoni, Francesca B Pizzini, Michela Pievan. Microstructural alterations in the locus coeruleus-entorhinal cortex pathway in Alzheimer's disease and frontotemporal dementia. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 1. 2024-01-12. PMID:38213948. |
microstructural alterations in the locus coeruleus-entorhinal cortex pathway in alzheimer's disease and frontotemporal dementia. |
2024-01-12 |
2024-01-14 |
Not clear |
| Giulia Quattrini, Lorenzo Pini, Ilaria Boscolo Galazzo, Ileana O Jelescu, Jorge Jovicich, Rosa Manenti, Giovanni B Frisoni, Moira Marizzoni, Francesca B Pizzini, Michela Pievan. Microstructural alterations in the locus coeruleus-entorhinal cortex pathway in Alzheimer's disease and frontotemporal dementia. Alzheimer's & dementia (Amsterdam, Netherlands). vol 16. issue 1. 2024-01-12. PMID:38213948. |
we investigated in vivo the microstructural integrity of the pathway connecting the locus coeruleus to the transentorhinal cortex (lc-tec) in patients with alzheimer's disease (ad) and frontotemporal dementia (ftd). |
2024-01-12 |
2024-01-14 |
Not clear |
| Liangdong Zhou, Thanh D Nguyen, Gloria C Chiang, Xiuyuan H Wang, Ke Xi, Tsung-Wei Hu, Emily B Tanzi, Tracy A Butler, Mony J de Leon, Yi L. Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-01-07. PMID:38184796. |
mapping of microscopic changes in the perivascular space (pvs) of the cerebral cortex, beyond magnetic resonance-visible pvs in white matter, may enhance our ability to diagnose alzheimer's disease (ad) early. |
2024-01-07 |
2024-01-09 |
Not clear |
| Xiang Zhou, Kangning Dong, Shihua Zhan. Integrating spatial transcriptomics data across different conditions, technologies and developmental stages. Nature computational science. vol 3. issue 10. 2024-01-04. PMID:38177758. |
we apply staligner to st datasets of the human cortex slices from different samples, the mouse olfactory bulb slices generated by two profiling technologies, the mouse hippocampus tissue slices under normal and alzheimer's disease conditions, and the spatiotemporal atlases of mouse organogenesis. |
2024-01-04 |
2024-01-07 |
mouse |
| Nisha Rani, Kylie H Alm, Caitlin A Corona-Long, Caroline L Speck, Anja Soldan, Corinne Pettigrew, Yuxin Zhu, Marilyn Albert, Arnold Bakke. Tau PET burden in Brodmann areas 35 and 36 is associated with individual differences in cognition in non-demented older adults. Frontiers in aging neuroscience. vol 15. 2024-01-01. PMID:38161595. |
the accumulation of neurofibrillary tau tangles, a neuropathological hallmark of alzheimer's disease (ad), occurs in medial temporal lobe (mtl) regions early in the disease process, with some of the earliest deposits localized to subregions of the entorhinal cortex. |
2024-01-01 |
2024-01-05 |
Not clear |
| Xingxing Li, Lei Chen, Kunqiang Yu, Wenhao Zhuang, Hui Zhu, Wenqiang Xu, Hui Yan, Gangqiao Qi, Dongsheng Zhou, Shaochang W. Impact of twice-a-day transcranial direct current stimulation intervention on cognitive function and motor cortex plasticity in patients with Alzheimer's disease. General psychiatry. vol 36. issue 6. 2023-12-29. PMID:38155843. |
impact of twice-a-day transcranial direct current stimulation intervention on cognitive function and motor cortex plasticity in patients with alzheimer's disease. |
2023-12-29 |
2023-12-31 |
Not clear |
| Zhijun He, Huajie Zhang, Xiaoqian Li, Liming Shen, Nan Li, Shuiyuan Cheng, Qiong Li. Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease. European journal of pharmacology. 2023-12-21. PMID:38128868. |
comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside a on alzheimer's disease. |
2023-12-21 |
2023-12-24 |
mouse |
| Rami Lee, Han Sang Lee, Won-Woo Kim, Manho Kim, Seung-Yeol Na. Cognitive function improvement effects of gintonin-enriched fraction in subjective memory impairment: An assessor- and participant-blinded placebo-controlled study. Journal of ginseng research. vol 47. issue 6. 2023-12-19. PMID:38107399. |
the gintonin-enriched fraction (gef) inhibits amyloid plaque accumulation in the cortex and hippocampus, improves cognitive dysfunction by increasing acetylcholine levels, and promoted hippocampal neurogenesis in an animal model of alzheimer's disease. |
2023-12-19 |
2023-12-21 |
human |
| Joseph Giorgio, Jenna N Adams, Anne Maass, William J Jagust, Michael Breakspea. Amyloid induced hyperexcitability in default mode network drives medial temporal hyperactivity and early tau accumulation. Neuron. 2023-12-14. PMID:38096815. |
in early alzheimer's disease (ad) β-amyloid (aβ) deposits throughout association cortex and tau appears in the entorhinal cortex (ec). |
2023-12-14 |
2023-12-17 |
Not clear |
| Xin Shen, Zhixiang Cui, Yidan Wei, Yingnan Huo, Duo Yu, Xin Zhang, Shirui Ma. Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider. Asian journal of pharmaceutical sciences. vol 18. issue 6. 2023-12-13. PMID:38089837. |
the number of people with alzheimer's disease (ad) is increasing annually, with the nidus mainly concentrated in the cortex and hippocampus. |
2023-12-13 |
2023-12-17 |
Not clear |
| Marios G Krokidis, Aristidis G Vrahatis, Konstantinos Lazaros, Konstantina Skolariki, Themis P Exarchos, Panagiotis Vlamo. Machine Learning Analysis of Alzheimer's Disease Single-Cell RNA-Sequencing Data across Cortex and Hippocampus Regions. Current issues in molecular biology. vol 45. issue 11. 2023-11-25. PMID:37998721. |
machine learning analysis of alzheimer's disease single-cell rna-sequencing data across cortex and hippocampus regions. |
2023-11-25 |
2023-11-28 |
mouse |
| Marios G Krokidis, Aristidis G Vrahatis, Konstantinos Lazaros, Konstantina Skolariki, Themis P Exarchos, Panagiotis Vlamo. Machine Learning Analysis of Alzheimer's Disease Single-Cell RNA-Sequencing Data across Cortex and Hippocampus Regions. Current issues in molecular biology. vol 45. issue 11. 2023-11-25. PMID:37998721. |
our methodology utilizes single-cell rna sequencing data from healthy and alzheimer's disease (ad) samples, focused on the cortex and hippocampus regions in mice. |
2023-11-25 |
2023-11-28 |
mouse |
| Matthew Rowan, Annie Goettemoeller, Emmie Banks, Katharine McCann, Prateek Kumar, Kelly South, Viktor Olah, Christina Ramelow, Duc Duong, Nicholas Seyfried, Srikant Rangaraju, David Weinshenke. Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology. Research square. 2023-11-21. PMID:37987015. |
in mouse models, early hyperexcitability has been shown in the entorhinal cortex, the first cortical region impacted by alzheimer's disease2-4. |
2023-11-21 |
2023-11-29 |
mouse |
| Jessica R Gaunt, Norliyana Zainolabidin, Alaric K K Yip, Jia Min Tan, Aloysius Y T Low, Albert I Chen, Toh Hean Ch'n. Cytokine enrichment in deep cerebellar nuclei is contributed by multiple glial populations and linked to reduced amyloid plaque pathology. Journal of neuroinflammation. vol 20. issue 1. 2023-11-18. PMID:37978387. |
alzheimer's disease (ad) pathology and amyloid-beta (aβ) plaque deposition progress slowly in the cerebellum compared to other brain regions, while the entorhinal cortex (ec) is one of the most vulnerable regions. |
2023-11-18 |
2023-11-20 |
mouse |
| Zhigao Wang, Xiaoxu Wang, Yingxu Ma, Peixu Cong, Xincen Wang, Yu Song, Jie Xu, Changhu Xu. Astaxanthin alleviates ganglioside metabolism disorder in the cortex of Alzheimer's disease mice. Food & function. 2023-11-06. PMID:37929718. |
astaxanthin alleviates ganglioside metabolism disorder in the cortex of alzheimer's disease mice. |
2023-11-06 |
2023-11-08 |
mouse |
| Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901036. |
basal forebrain activity predicts functional degeneration in the entorhinal cortex in alzheimer's disease. |
2023-10-30 |
2023-11-08 |
Not clear |
| Marthe Mieling, Martin Göttlich, Mushfa Yousuf, Nico Bunzec. Basal forebrain activity predicts functional degeneration in the entorhinal cortex in Alzheimer's disease. Brain communications. vol 5. issue 5. 2023-10-30. PMID:37901036. |
recent models of alzheimer's disease suggest the nucleus basalis of meynert (nbm) as an early origin of structural degeneration followed by the entorhinal cortex (ec). |
2023-10-30 |
2023-11-08 |
Not clear |
| Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. |
localization of pde4d, hcn1 channels, and mglur3 in rhesus macaque entorhinal cortex may confer vulnerability in alzheimer's disease. |
2023-10-24 |
2023-11-08 |
monkey |
| Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. |
alzheimer's disease cortical tau pathology initiates in the layer ii cell clusters of entorhinal cortex, but it is not known why these specific neurons are so vulnerable. |
2023-10-24 |
2023-11-08 |
monkey |
| Kayo Yukawa, Satomi Yamamoto-Mcguire, Louis Cafaro, Christine Hong, Fredrik Kamme, Tsuneya Ikezu, Seiko Ikez. Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice. Acta neuropathologica communications. vol 11. issue 1. 2023-10-20. PMID:37853497. |
tau tubulin kinase-1 (ttbk1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in alzheimer's disease (ad). |
2023-10-20 |
2023-11-08 |
mouse |