All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Helena Colvee-Martin, Juan Rayo Parra, Gabriel Antonio Gonzalez, Warren Barker, Ranjan Duar. Neuropathology, Neuroimaging, and Fluid Biomarkers in Alzheimer's Disease. Diagnostics (Basel, Switzerland). vol 14. issue 7. 2024-04-13. PMID:38611617. the known hallmarks of alzheimer's disease include amyloid-β plaques and neurofibrillary tau tangles. 2024-04-13 2024-04-15 Not clear
Helena Colvee-Martin, Juan Rayo Parra, Gabriel Antonio Gonzalez, Warren Barker, Ranjan Duar. Neuropathology, Neuroimaging, and Fluid Biomarkers in Alzheimer's Disease. Diagnostics (Basel, Switzerland). vol 14. issue 7. 2024-04-13. PMID:38611617. it is now clear that an imbalance between production and clearance of the amyloid beta protein and related aβ peptides, especially aβ42, is a very early, initiating factor in alzheimer's disease (ad) pathogenesis, leading to aggregates of hyperphosphorylation and misfolded tau protein, inflammation, and neurodegeneration. 2024-04-13 2024-04-15 Not clear
Maciej Zadrozny, Patrycja Drapich, Anna Gasiorowska-Bien, Wiktor Niewiadomski, Charles R Harrington, Claude M Wischik, Gernot Riedel, Grazyna Niewiadomsk. Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model. Cells. vol 13. issue 7. 2024-04-12. PMID:38607082. basal forebrain cholinergic dysfunction, most likely linked with tau protein aggregation, is a characteristic feature of alzheimer's disease (ad). 2024-04-12 2024-04-14 mouse
Liara Rizzi, Lea T Grinber. Publisher Correction: Exploring the significance of caspase-cleaved tau in tauopathies and as a complementary pathology to phospho-tau in Alzheimer's disease: implications for biomarker development and therapeutic targeting. Acta neuropathologica communications. vol 12. issue 1. 2024-04-12. PMID:38610041. publisher correction: exploring the significance of caspase-cleaved tau in tauopathies and as a complementary pathology to phospho-tau in alzheimer's disease: implications for biomarker development and therapeutic targeting. 2024-04-12 2024-04-15 Not clear
Jacob Ziontz, Theresa M Harrison, Xi Chen, Joseph Giorgio, Jenna N Adams, Zehao Wang, William Jagus. Behaviorally meaningful functional networks mediate the effect of Alzheimer's pathology on cognition. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 4. 2024-04-11. PMID:38602736. tau pathology is associated with cognitive impairment in both aging and alzheimer's disease, but the functional and structural bases of this relationship remain unclear. 2024-04-11 2024-04-13 Not clear
Motonobu Fujishima, Yohei Kawasaki, Toshiharu Mitsuhashi, Hiroshi Matsud. Impact of amyloid and tau positivity on longitudinal brain atrophy in cognitively normal individuals. Alzheimer's research & therapy. vol 16. issue 1. 2024-04-10. PMID:38600602. individuals on the preclinical alzheimer's continuum, particularly those with both amyloid and tau positivity (a + t +), display a rapid cognitive decline and elevated disease progression risk. 2024-04-10 2024-04-13 Not clear
Ann-Charlotte Granholm, Eric D Hamlet. The Role of Tau Pathology in Alzheimer's Disease and Down Syndrome. Journal of clinical medicine. vol 13. issue 5. 2024-04-09. PMID:38592182. the role of tau pathology in alzheimer's disease and down syndrome. 2024-04-09 2024-04-11 Not clear
Tim Bathe, Gabriela P Hery, Jonathan A B Villareal, Jennifer L Phillips, Eric M Cohen, Rohan V Sharma, Wangchen Tsering, Stefan Proko. Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies. Acta neuropathologica communications. vol 12. issue 1. 2024-04-08. PMID:38581050. to better characterize the interplay between different extracellular and intracellular protein pathologies and the brain's intrinsic immune system in nd, we set out to comprehensively profile the local immune response in postmortem brain samples of individuals with "pure" beta-amyloid and tau pathology (ad), "pure" α-synuclein pathology in lewy body diseases (lbd), as well as cases with alzheimer's disease neuropathological changes (adnc) and lewy body pathology (mix). 2024-04-08 2024-04-10 human
Ke Hou, Peng Ge, Michael R Sawaya, Joshua L Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon, David S Eisenber. How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585812. how short peptides can disassemble ultra-stable tau fibrils extracted from alzheimer's disease brain by a strain-relief mechanism. 2024-04-08 2024-04-10 Not clear
Ke Hou, Peng Ge, Michael R Sawaya, Joshua L Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon, David S Eisenber. How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585812. reducing fibrous aggregates of protein tau is a possible strategy for halting progression of alzheimer's disease (ad). 2024-04-08 2024-04-10 Not clear
Dmytro Morderer, Melissa C Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil, Nora Pobitzer, Michelle Salemi, Brett S Phinney, Dennis W Dickson, Melissa E Murray, Wilfried Rossol. Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585836. to comprehensively investigate the common and unique protein interactors associated with the variety of tau lesions present across different human tauopathies, alzheimer's disease (ad), corticobasal degeneration (cbd), pick's disease (pid), and progressive supranuclear palsy (psp), were selected to represent the major tauopathy diseases. 2024-04-08 2024-04-10 human
Kira Breunig, Xiufen Lei, Mauro Montalbano, Gabriela D A Guardia, Shiva Ostadrahimi, Victoria Alers, Adam Kosti, Jennifer Chiou, Nicole Klein, Corina Vinarov, Lily Wang, Mujia Li, Weidan Song, W Lee Kraus, David S Libich, Stefano Tiziani, Susan T Weintraub, Pedro A F Galante, Luiz O F Penalv. SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585848. we uncovered novel serbp1 roles in splicing, cell division, and ribosomal biogenesis and showed its participation in pathological stress granules and tau aggregates in alzheimer's disease brains. 2024-04-08 2024-04-10 Not clear
Gustavo A Patow, Anira Escrichs, Petra Ritter, Gustavo Dec. Whole-Brain Dynamics Disruptions in the Progression of Alzheimer's Disease: Understanding the Influence of Amyloid-Beta and Tau. bioRxiv : the preprint server for biology. 2024-04-08. PMID:38585882. whole-brain dynamics disruptions in the progression of alzheimer's disease: understanding the influence of amyloid-beta and tau. 2024-04-08 2024-04-10 Not clear
Jie Wang, Qi Huang, Xing Chen, Zhiwen You, Kun He, Qihao Guo, Yiyun Huang, Yang Yang, Zengping Lin, Tengfei Guo, Jun Zhao, Yihui Guan, Binyin Li, Fang Xi. Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer's disease. Molecular psychiatry. 2024-04-08. PMID:38589563. tau pathology is associated with synaptic density and longitudinal synaptic loss in alzheimer's disease. 2024-04-08 2024-04-11 human
Jie Wang, Qi Huang, Xing Chen, Zhiwen You, Kun He, Qihao Guo, Yiyun Huang, Yang Yang, Zengping Lin, Tengfei Guo, Jun Zhao, Yihui Guan, Binyin Li, Fang Xi. Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer's disease. Molecular psychiatry. 2024-04-08. PMID:38589563. the associations of synaptic loss with amyloid-β (aβ) and tau pathology measured by positron emission tomography (pet) and plasma analysis in alzheimer's disease (ad) patients are unknown. 2024-04-08 2024-04-11 human
Michael Anekson Widjaya, Shin-Da Lee, Wei-Chung Cheng, Bor-Tsang W. Effects of Exercise Training on Immune-Related Genes and Pathways in the Cortex of Animal Models of Alzheimer's Disease: A Systematic Review. Journal of Alzheimer's disease : JAD. 2024-04-05. PMID:38578886. alzheimer's disease (ad) is a chronic neurodegenerative disease that affects the immune system due to the accumulation of amyloid-β (aβ) and tau associated molecular pathology and other pathogenic processes. 2024-04-05 2024-04-10 Not clear
Estela Area-Gomez, Eric A Scho. Towards a Unitary Hypothesis of Alzheimer's Disease Pathogenesis. Journal of Alzheimer's disease : JAD. 2024-04-05. PMID:38578892. the "amyloid cascade" hypothesis of alzheimer's disease (ad) pathogenesis invokes the accumulation in the brain of plaques (containing the amyloid-β protein precursor [aβpp] cleavage product amyloid-β [aβ]) and tangles (containing hyperphosphorylated tau) as drivers of pathogenesis. 2024-04-05 2024-04-10 Not clear
Erica Acquarone, Elentina K Argyrousi, Ottavio Arancio, D Martin Watterson, Saktimayee M Ro. The 5HT2b Receptor in Alzheimer's Disease: Increased Levels in Patient Brains and Antagonist Attenuation of Amyloid and Tau Induced Dysfunction. Journal of Alzheimer's disease : JAD. 2024-04-05. PMID:38578894. the 5ht2b receptor in alzheimer's disease: increased levels in patient brains and antagonist attenuation of amyloid and tau induced dysfunction. 2024-04-05 2024-04-10 Not clear
Umberto Nencha, Isotta Rigoni, Federica Ribaldi, Daniele Altomare, Margitta Seeck, Valentina Garibotto, Serge Vulliémoz, Giovanni B Frison. Alterations in gamma frequency oscillations correlate with cortical tau deposition in Alzheimer's disease. Neurobiology of aging. vol 139. 2024-04-04. PMID:38574424. alterations in gamma frequency oscillations correlate with cortical tau deposition in alzheimer's disease. 2024-04-04 2024-04-07 Not clear
Umberto Nencha, Isotta Rigoni, Federica Ribaldi, Daniele Altomare, Margitta Seeck, Valentina Garibotto, Serge Vulliémoz, Giovanni B Frison. Alterations in gamma frequency oscillations correlate with cortical tau deposition in Alzheimer's disease. Neurobiology of aging. vol 139. 2024-04-04. PMID:38574424. we assessed the relationship of gamma oscillations with tau deposition in alzheimer's disease (ad) and other cognitive diseases, as both are altered during the disease course and relate to neurodegeneration. 2024-04-04 2024-04-07 Not clear