| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sauradeep Sarkar, Ari G Chack. Surgery for Acromegaly. Neurology India. vol 68. issue Supplement. 2021-04-14. PMID:32611892. |
growth hormone (gh) hypersecretion from a pituitary adenoma results in acromegaly, an endocrinological disorder with multiple systemic manifestations that presents several unique challenges in terms of perioperative management and long term outcomes. |
2021-04-14 |
2023-08-13 |
Not clear |
| Kensaku Fukunaga, Hitomi Imachi, Seisuke Sato, Toshihiro Kobayashi, Yuki Yoshioka, Takanobu Saheki, Natsuki Ban, Kurumi Urushihara, Jingya Lyu, Tao Dong, Ryou Ishikawa, Kyuichi Kadota, Reiji Haba, Naoko Inoshita, Koji Mura. Successful Therapy Using Pasireotide Long-acting Release for Cushing's Disease Merged with Biochemical Acromegaly. Internal medicine (Tokyo, Japan). vol 60. issue 7. 2021-04-14. PMID:33162471. |
five years later, she was diagnosed with recurrent cushing's disease and biochemical acromegaly because of elevated levels of serum growth hormone (gh), plasma insulin-like growth factor-1, plasma adrenocorticotropic hormone (acth), and the 24-hour urinary excretion of free cortisol. |
2021-04-14 |
2023-08-13 |
Not clear |
| Amit Akirov, Hiba Masri-Iraqi, Idit Dotan, Ilan Shimo. The Biochemical Diagnosis of Acromegaly. Journal of clinical medicine. vol 10. issue 5. 2021-04-08. PMID:33803429. |
the most important assays for the biochemical diagnosis and management of acromegaly are growth hormone (gh) and insulin-like growth factor-1 (igf-1). |
2021-04-08 |
2023-08-13 |
Not clear |
| Leila Hedayati Zafarghandi, Mohammad Ebrahim Khamseh, Milad Fooladgar, Shahrzad Mohseni, Mostafa Qorbani, Nahid Hashemi Madani, Mahboobeh Hemmatabadi, MohammadReza Mohajeri-Tehrani, Nooshin Shirza. Pretreatment serum GH levels and cardio-metabolic comorbidities in acromegaly; analysis of data from Iran Pituitary Tumor Registry. Journal of diabetes and metabolic disorders. vol 19. issue 1. 2021-04-05. PMID:32550182. |
pretreatment serum gh levels and cardio-metabolic comorbidities in acromegaly; analysis of data from iran pituitary tumor registry. |
2021-04-05 |
2023-08-13 |
Not clear |
| Leila Hedayati Zafarghandi, Mohammad Ebrahim Khamseh, Milad Fooladgar, Shahrzad Mohseni, Mostafa Qorbani, Nahid Hashemi Madani, Mahboobeh Hemmatabadi, MohammadReza Mohajeri-Tehrani, Nooshin Shirza. Pretreatment serum GH levels and cardio-metabolic comorbidities in acromegaly; analysis of data from Iran Pituitary Tumor Registry. Journal of diabetes and metabolic disorders. vol 19. issue 1. 2021-04-05. PMID:32550182. |
acromegaly is a rare chronic disabling disorder, in which growth hormone (gh) excess is associated with a range of clinical features and systemic complications. |
2021-04-05 |
2023-08-13 |
Not clear |
| Leila Hedayati Zafarghandi, Mohammad Ebrahim Khamseh, Milad Fooladgar, Shahrzad Mohseni, Mostafa Qorbani, Nahid Hashemi Madani, Mahboobeh Hemmatabadi, MohammadReza Mohajeri-Tehrani, Nooshin Shirza. Pretreatment serum GH levels and cardio-metabolic comorbidities in acromegaly; analysis of data from Iran Pituitary Tumor Registry. Journal of diabetes and metabolic disorders. vol 19. issue 1. 2021-04-05. PMID:32550182. |
the present study aims to evaluate the association between pretreatment basal gh levels as well as gh levels after oral glucose tolerance test (ogtt) and cardio-metabolic comorbidities, including diabetes mellitus (dm), left ventricular hypertrophy (lvh) and hypertension (htn) in patients with active acromegaly. |
2021-04-05 |
2023-08-13 |
Not clear |
| Cesar Luiz Boguszewski, Margaret Cristina da Silva Boguszewski, Wouter W de Herde. From dwarves to giants: South American's contribution to the history of growth hormone and related disorders. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 50. 2021-03-16. PMID:31864177. |
importantly, we present an overview of the outstanding medical contribution of jose dantas de souza leite, a brazilian physician that described the first cases of acromegaly, and bernardo alberto houssay, an argentine researcher graced with the nobel prize, who was one the first scientists to establish a link between gh and glucose metabolism. |
2021-03-16 |
2023-08-13 |
human |
| Claudia Campana, Giuliana Corica, Federica Nista, Francesco Cocchiara, Giulia Graziani, Keyvan Khorrami, Marta Franco, Mara Boschetti, Diego Ferone, Federico Gatt. Emerging drugs for the treatment of acromegaly. Expert opinion on emerging drugs. vol 25. issue 4. 2021-03-16. PMID:32938258. |
acromegaly is a disease characterized by elevated growth hormone (gh) and insulin-like growth factor 1 (igf-1) levels. |
2021-03-16 |
2023-08-13 |
Not clear |
| Akanksha Jain, Shipra Gupta, Anil Bhansali, Mili Gupta, Ashish Jain, Nandini Bhaskar, Rose Kanwaljeet Kau. Impact of concurrent diabetes on periodontal health in patients with acromegaly. Scientific reports. vol 10. issue 1. 2021-03-08. PMID:33154456. |
serum gh, igf1, hba1c, pituitary hormones and mri sella were performed in patients with acromegaly. |
2021-03-08 |
2023-08-13 |
Not clear |
| Anat Ben-Shlomo, Nan Deng, Evelyn Ding, Masaaki Yamamoto, Adam Mamelak, Vera Chesnokova, Artak Labadzhyan, Shlomo Melme. DNA damage and growth hormone hypersecretion in pituitary somatotroph adenomas. The Journal of clinical investigation. vol 130. issue 11. 2021-02-16. PMID:32673291. |
octreotide, a somatostatin receptor ligand that targets somatotroph adenoma gh secretion in patients with acromegaly, inhibited camp and gh and reversed dna damage induction. |
2021-02-16 |
2023-08-13 |
mouse |
| Awatef Alotaibi, Ahmad Habib, Moutaz Osman, Khaled Alzahrani, Faisal Alzahran. Pseudoacromegaly Associated with Non-Functioning Pituitary Adenoma. European journal of case reports in internal medicine. vol 7. issue 12. 2021-02-12. PMID:33313006. |
acromegaly is characterized by excess skin and soft tissue growth due to increased growth hormone (gh) levels. |
2021-02-12 |
2023-08-13 |
Not clear |
| Filippo Maffezzoni, Teresa Porcelli, Andrea Delbarba, Letizia Pezzaioli, Carlo Cappelli, Alberto Ferli. Biomarkers of Acromegaly and Growth Hormone Action. Protein and peptide letters. vol 27. issue 12. 2021-02-04. PMID:32310036. |
gh and insulin-like growth factor-i (igf-i) are the main biomarkers of gh action in children and adults while, in acromegaly, both gh and igf-i are established biomarkers of disease activity. |
2021-02-04 |
2023-08-13 |
Not clear |
| Filippo Maffezzoni, Teresa Porcelli, Andrea Delbarba, Letizia Pezzaioli, Carlo Cappelli, Alberto Ferli. Biomarkers of Acromegaly and Growth Hormone Action. Protein and peptide letters. vol 27. issue 12. 2021-02-04. PMID:32310036. |
however, although gh and igf-i are widely validated biomarkers of ghd and acromegaly, their role is not completely exhaustive or suitable for clinical classification and follow-up. |
2021-02-04 |
2023-08-13 |
Not clear |
| Filippo Maffezzoni, Teresa Porcelli, Andrea Delbarba, Letizia Pezzaioli, Carlo Cappelli, Alberto Ferli. Biomarkers of Acromegaly and Growth Hormone Action. Protein and peptide letters. vol 27. issue 12. 2021-02-04. PMID:32310036. |
therefore, new biological markers for acromegaly and gh replacement therapy are strongly needed. |
2021-02-04 |
2023-08-13 |
Not clear |
| Filippo Maffezzoni, Teresa Porcelli, Andrea Delbarba, Letizia Pezzaioli, Carlo Cappelli, Alberto Ferli. Biomarkers of Acromegaly and Growth Hormone Action. Protein and peptide letters. vol 27. issue 12. 2021-02-04. PMID:32310036. |
the aim of this paper is to review and summarize the current state in the field pointing out new potential biomarkers for acromegaly and gh use/abuse. |
2021-02-04 |
2023-08-13 |
Not clear |
| Sabrina Chiloiro, Federica Mirra, Donfrancesco Federico, Antonella Giampietro, Felicia Visconti, Laura Rossi, Alfredo Pontecorvi, Laura De Marinis, Antonio Bianch. The Role of Growth Hormone Receptor Isoforms and Their Effects in Bone Metabolism and Skeletal Fragility. Protein and peptide letters. vol 27. issue 12. 2021-02-04. PMID:32543356. |
the aim of this review is to evaluate the role of gh receptor polymorphisms in skeletal fragility in patients affected by ghd and acromegaly. |
2021-02-04 |
2023-08-13 |
Not clear |
| b' Soraya Puglisi, Francesco Ferra\\xc3\\xb9, Marta Ragonese, Federica Spagnolo, Salvatore Cannav\\xc3\\xb. Cardiometabolic Risk in Acromegaly: A Review With a Focus on Pasireotide. Frontiers in endocrinology. vol 11. 2021-02-03. PMID:32117056.' |
acromegaly is a disease due to chronic gh excess and a consequent rise in igf-1 levels. |
2021-02-03 |
2023-08-13 |
Not clear |
| Man Lu, Jack U Flanagan, Ries J Langley, Michael P Hay, Jo K Perr. Targeting growth hormone function: strategies and therapeutic applications. Signal transduction and targeted therapy. vol 4. 2021-02-01. PMID:30775002. |
in adults, hypersecretion of gh causes acromegaly, and strategies that block the release of gh or that inhibit gh receptor (ghr) activation are the primary forms of medical therapy for this disease. |
2021-02-01 |
2023-08-13 |
human |
| Bekir Ucan, Muhammed Kizilgul, Alper Cagri Karci, Hakan Duger, Muhammed Erkam Sencar, Narin Nasiroglu Imga, Taner Demirci, Dilek Berker, Erman Caka. THE PREVALENCE OF CANCER AND ITS RELATION TO DISEASE ACTIVITY IN PATIENTS WITH ACROMEGALY: TWO CENTERS' EXPERIENCE. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. vol 27. issue 1. 2021-01-25. PMID:33475501. |
acromegaly is characterized by increased serum concentrations of growth hormone (gh) and insulin-like growth factor 1 (igf-1). |
2021-01-25 |
2023-08-13 |
human |
| Thalijn Liliana Catharina Wolters, Charlotte Dinka Christina Corrina van der Heijden, Nathasja van Leeuwen, Bregina Tonny Petra Hijmans-Kersten, Mihai Gheorghe Netea, Jan Wa Smit, Dick Henricus Julianus Thijssen, Ad Hermus, Niels Peter Riksen, Romana Netea-Maie. Persistent inflammation and endothelial dysfunction in patients with treated acromegaly. Endocrine connections. vol 8. issue 12. 2021-01-22. PMID:31751301. |
acromegaly is characterized by an excess of growth hormone (gh) and insulin-like growth factor 1 (igf1). |
2021-01-22 |
2023-08-13 |
Not clear |