| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joseph A M J L Jansse. Mechanisms of putative IGF-I receptor resistance in active acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 52. 2021-07-05. PMID:32339897. |
although igf-i can directly improve insulin sensitivity and glucose uptake in muscles, the excessive gh secretion in active acromegaly frequently leads to insulin resistance, glucose intolerance and even diabetes. |
2021-07-05 |
2023-08-13 |
Not clear |
| Joseph A M J L Jansse. Mechanisms of putative IGF-I receptor resistance in active acromegaly. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 52. 2021-07-05. PMID:32339897. |
the development of a degree of igf-ir resistance for metabolic actions may help to explain why in active acromegaly diabetogenic effects of gh predominate and are not completely counteracted and neutralized by elevated circulating levels of igf-i. |
2021-07-05 |
2023-08-13 |
Not clear |
| Chin Taweesomboonyat, Thakul Oearsaku. Prognostic Factors of Acromegalic Patients with Growth Hormone-Secreting Pituitary Adenoma After Transsphenoidal Surgery. World neurosurgery. vol 146. 2021-07-05. PMID:33309643. |
acromegaly is a rare, chronic disorder that mostly results from growth hormone (gh)-secreting pituitary adenoma. |
2021-07-05 |
2023-08-13 |
Not clear |
| Sema Hepşen, Pinar Akhanli, Hakan Düğer, Murat Çalapkulu, Bekir Uçan, Muhammed Erkam Sencar, Davut Sakiz, Ilknur Öztürk Ünsal, Seyit Murat Bayram, Mustafa Özbek, Erman Çaka. Fatty Acid-Binding Protein-4 May Be a Biomarker Predicting Acromegaly-Associated Diabetes Mellitus. Turkish journal of medical sciences. 2021-07-04. PMID:34217172. |
the known pathogenesis of diabetes mellitus (dm) in acromegaly is mainly based on growth hormone (gh) and insulin-like growth factor-1 (igf-1) excess. |
2021-07-04 |
2023-08-13 |
Not clear |
| Maria Rosaria Ambrosio, Irene Gagliardi, Sabrina Chiloiro, Ana Gonçalves Ferreira, Marta Bondanelli, Antonella Giampietro, Antonio Bianchi, Laura De Marinis, Maria Fleseriu, Maria Chiara Zatell. Acromegaly in the elderly patients. Endocrine. vol 68. issue 1. 2021-06-21. PMID:32060689. |
acromegaly is a rare disease characterized by a chronic exposition to growth hormone (gh) and insulin-like growth factor-1 (igf-1), caused in most cases by a pituitary gh-secreting adenoma. |
2021-06-21 |
2023-08-13 |
Not clear |
| Marcelo Lemos Vieira da Cunha, Luis Alencar Biurrum Borba, Cesar Luiz Boguszewsk. Random Gh and Igf-I levels after transsphenoidal surgery for acromegaly: relation with long-term remission. Endocrine. vol 68. issue 1. 2021-06-21. PMID:32078118. |
random gh and igf-i levels after transsphenoidal surgery for acromegaly: relation with long-term remission. |
2021-06-21 |
2023-08-13 |
Not clear |
| Marcelo Lemos Vieira da Cunha, Luis Alencar Biurrum Borba, Cesar Luiz Boguszewsk. Random Gh and Igf-I levels after transsphenoidal surgery for acromegaly: relation with long-term remission. Endocrine. vol 68. issue 1. 2021-06-21. PMID:32078118. |
to evaluate the role of igf-i and random gh measurements 3 months after transsphenoidal surgery (tss) in predicting long-term remission in acromegaly patients. |
2021-06-21 |
2023-08-13 |
Not clear |
| Tao Xie, Yifan Tang, Rongkui Luo, Xiaobiao Zhang, Silin Wu, Ye Gu, Tengfei Liu, Fan H. GPR64 promotes cAMP pathway in tumor aggressiveness in sparsely granulated growth hormone cell adenomas. Endocrine. vol 68. issue 3. 2021-06-21. PMID:32180116. |
there is an increasing agreement that acromegaly caused by growth hormone (gh) cell adenoma has two distinct subtypes: densely granulated (dg) and sparsely granulated (sg). |
2021-06-21 |
2023-08-13 |
Not clear |
| Kyle Tamshen, Yue Wang, Stephen M F Jamieson, Jo K Perry, Heather D Maynar. Genetic Code Expansion Enables Site-Specific PEGylation of a Human Growth Hormone Receptor Antagonist through Click Chemistry. Bioconjugate chemistry. vol 31. issue 9. 2021-06-21. PMID:32786367. |
regulation of human growth hormone (gh) signaling has important applications in the remediation of several diseases including acromegaly and cancer. |
2021-06-21 |
2023-08-13 |
human |
| Nyasatu G Chamba, Ahlam A Amour, Abid M Sadiq, Tecla R Lyamuya, Emmanuel V Assey, Adnan M Sadiq, William P Howlet. Status epilepticus and diabetes ketoacidosis: uncommon clinical presentations of acromegaly. Endocrinology, diabetes & metabolism case reports. vol 2021. 2021-06-21. PMID:33960324. |
acromegaly is a rare disease caused by hypersecretion of the growth hormone (gh). |
2021-06-21 |
2023-08-13 |
Not clear |
| Nyasatu G Chamba, Ahlam A Amour, Abid M Sadiq, Tecla R Lyamuya, Emmanuel V Assey, Adnan M Sadiq, William P Howlet. Status epilepticus and diabetes ketoacidosis: uncommon clinical presentations of acromegaly. Endocrinology, diabetes & metabolism case reports. vol 2021. 2021-06-21. PMID:33960324. |
the gh producing tumors present with clinical manifestations of acromegaly due to excessive gh secretion or symptoms resulting from mass effects of the enlarging tumor. |
2021-06-21 |
2023-08-13 |
Not clear |
| Sylvia L Asa, Shereen Ezza. An Update on Pituitary Neuroendocrine Tumors Leading to Acromegaly and Gigantism. Journal of clinical medicine. vol 10. issue 11. 2021-06-15. PMID:34067494. |
when gh excess has its onset after epiphyseal fusion at puberty, the overgrowth of soft tissue and bone results in acromegaly. |
2021-06-15 |
2023-08-13 |
Not clear |
| Jean Kim, Ju Hun Oh, Heather Harlem, Michael D Culler, Cheol Ryong Ku, Eun Jig Le. Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas. Endocrinology and metabolism (Seoul, Korea). vol 35. issue 1. 2021-06-14. PMID:32207278. |
acromegaly is a rare disease primarily caused by growth hormone (gh)-secreting pituitary adenomas, and its treatment is costly. |
2021-06-14 |
2023-08-13 |
Not clear |
| Tyler Cardinal, Martin J Rutkowski, Alexander Micko, Mark Shiroishi, Chia-Shang Jason Liu, Bozena Wrobel, John Carmichael, Gabriel Zad. Impact of tumor characteristics and pre- and postoperative hormone levels on hormonal remission following endoscopic transsphenoidal surgery in patients with acromegaly. Neurosurgical focus. vol 48. issue 6. 2021-06-14. PMID:32480366. |
acromegaly is a disease of acral enlargement and elevated serum levels of insulin-like growth factor-1 (igf-1) and growth hormone (gh), usually caused by a pituitary adenoma. |
2021-06-14 |
2023-08-13 |
Not clear |
| João Vitor Gerdulli Tamanini, Mateus Dal Fabbro, Leandro Luiz Lopes de Freitas, José Vassallo, Luciano de Souza Queiroz, Fabio Rogeri. Digital analysis of hormonal immunostaining in pituitary adenomas classified according to WHO 2017 criteria and correlation with preoperative laboratory findings. Neurosurgical focus. vol 48. issue 6. 2021-06-14. PMID:32480373. |
the authors sought to evaluate clinical and laboratory data from pituitary adenoma (pa) patients with functioning pa (associated with acromegaly [n = 10] or cushing disease [n = 10]) or nonfunctioning pa (nfpa; n = 10) that were classified according to 2017 who criteria (based on the expression of the transcription factors pituitary-specific positive transcription factor 1 [pit-1], a transcription factor member of the t-box family [tpit], and steroidogenic factor 1 [sf-1]) and to assess the immunostaining results for growth hormone (gh) and adrenocorticotropic hormone (acth) in the corresponding tumors. |
2021-06-14 |
2023-08-13 |
Not clear |
| Mahshid Heydari, Nahid Hashemi-Madani, Zahra Emami, Alireza Khajavi, Mohammad Ghorbani, Mojtaba Malek, Manizhe Ataei Kachuee, Mohammad E Khamse. Post-treatment heterogeneity of cardiometabolic risk in patients with acromegaly: The impact of GH and IGF-1. Endocrine research. 2021-06-14. PMID:34102938. |
post-treatment heterogeneity of cardiometabolic risk in patients with acromegaly: the impact of gh and igf-1. |
2021-06-14 |
2023-08-13 |
Not clear |
| Mussa Hussain AlMalki, Maswood M Ahmad, Badurudeen M Buhary, Rashid Aljawair, Arwa Alyamani, Amani Alhozali, Awad Alshahrani, Saud Alzahrani, Tariq Nasser, Wael Alzahrani, Hussain Raef, Mohamed Aldawish, Aishah Elkhzaim. Clinical features and therapeutic outcomes of patients with acromegaly in Saudi Arabia: a retrospective analysis. Hormones (Athens, Greece). vol 19. issue 3. 2021-06-04. PMID:32388630. |
acromegaly is a rare disease resulting in clinical sequelae with significant morbidity and mortality due to the central tumor mass effect and prolonged growth hormone (gh) hypersecretion. |
2021-06-04 |
2023-08-13 |
Not clear |
| Peter Kamenický, Luigi Maione, Philippe Chanso. Cardiovascular complications of acromegaly. Annales d'endocrinologie. vol 82. issue 3-4. 2021-05-28. PMID:33168155. |
acromegaly is a chronic disease due to growth hormone (gh) and insulin-like growth factor 1 (igf-1) excess. |
2021-05-28 |
2023-08-13 |
Not clear |
| V Amodru, P Petrossians, A Colao, B Delemer, L Maione, S J C M M Neggers, B Decoudier, P Kamenicky, F Castinetti, V Hana, R Pivonello, D Carvalho, T Brue, A Beckers, P Chanson, T Cun. Discordant biological parameters of remission in acromegaly do not increase the risk of hypertension or diabetes: a study with the Liege Acromegaly Survey database. Endocrine. vol 70. issue 1. 2021-05-27. PMID:32562181. |
acromegaly is a rare disease due to growth hormone (gh)-secreting pituitary adenoma. |
2021-05-27 |
2023-08-13 |
Not clear |
| Denise Costa, Filippo Ceccato, Rosa Lauretta, Valeria Mercuri, Tania D'Amico, Corrado De Vito, Carla Scaroni, Marialuisa Appetecchia, Patrizia Gargiul. The prevalence of secondary neoplasms in acromegalic patients: possible preventive and/or protective role of metformin. International journal of clinical oncology. vol 26. issue 6. 2021-05-25. PMID:33713207. |
acromegaly is a rare disease due to chronic growth hormone (gh) excess and the consequent increase in insulin-like growth factor-1 (igf-1) levels. |
2021-05-25 |
2023-08-13 |
Not clear |