| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Austin W Merrill, Linda S Barter, Uwe Rudolph, Edmond I Eger, Joseph F Antognini, Mirela Iodi Carstens, E Carsten. Propofol's effects on nociceptive behavior and spinal c-fos expression after intraplantar formalin injection in mice with a mutation in the gamma-aminobutyric acid-type(A) receptor beta3 subunit. Anesthesia and analgesia. vol 103. issue 2. 2006-08-09. PMID:16861438. |
we investigated whether propofol affected nociceptive behavior and fos-like immunoreactivity (fli) in the lumbo-sacral spinal cord after intraplantar formalin injection in wild-type (wt) mice and in mutant mice harboring a point mutation of the gamma-aminobutyric acid type(a) receptor, which renders them resistant to propofol. |
2006-08-09 |
2023-08-12 |
mouse |
| Zhen Li, Ceng Luo, Yan-Yan Sun, Jun Che. [Effects of etomidate on local synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord]. Sheng li xue bao : [Acta physiologica Sinica]. vol 56. issue 3. 2006-07-21. PMID:15224160. |
by prolonging the mean open time of gaba(a) receptors, however, et has no direct effect on local excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord. |
2006-07-21 |
2023-08-12 |
rat |
| Chao-Ling Qu, Jing-Shi Tang, Hong Ji. Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex. Brain research. vol 1073-1074. 2006-07-19. PMID:16448630. |
these results suggest that the gaba(a) receptor is involved in the modulation of vlo morphine-induced antinociception, and provide a behavioral support for the hypothesis that morphine may directly inhibit the gabaergic inhibitory interneurons leading to indirect activation of the descending antinociceptive pathway through a disinhibitory effect on the vlo output neurons and depression of the nociceptive inputs at the spinal cord level. |
2006-07-19 |
2023-08-12 |
rat |
| Jun Liu, Changfeng Tai, William C de Groat, Xiang-min Peng, Marina Mata, David J Fin. Release of GABA from sensory neurons transduced with a GAD67-expressing vector occurs by non-vesicular mechanisms. Brain research. vol 1073-1074. 2006-07-19. PMID:16460707. |
the amount of gaba released from a spinal cord slice preparation, prepared from animals transduced by subcutaneous inoculation of qhgad67 in the hind paws, was substantially increased compared to animals transduced with control vector q0zhg or normal animals, but the amount of gaba released was not changed by stimulation of the dorsal roots at either low (0.1 ma, 0.5-ms duration) or high (10 ma, 0.5-ms duration) intensity. |
2006-07-19 |
2023-08-12 |
Not clear |
| L Bremner, M Fitzgerald, M Bacce. Functional GABA(A)-receptor-mediated inhibition in the neonatal dorsal horn. Journal of neurophysiology. vol 95. issue 6. 2006-07-17. PMID:16687622. |
to investigate whether functional gaba(a)r-mediated inhibition does indeed undergo postnatal regulation at the level of dorsal horn circuits, we applied the selective gaba(a)r antagonist gabazine to the spinal cord in anesthetized rat pups [postnatal day (p) 3 or 21] while recording spike activity in single lumbar dorsal horn cells in vivo. |
2006-07-17 |
2023-08-12 |
rat |
| Frank P Elsen, Patricia Liljelund, David F Werner, Richard W Olsen, Gregg E Homanics, Neil L Harriso. GABA(A)-R alpha1 subunit knockin mutation leads to abnormal EEG and anesthetic-induced seizure-like activity in mice. Brain research. vol 1078. issue 1. 2006-07-06. PMID:16490182. |
gaba(a)-rs containing alpha1 subunits do not appear to contribute to the actions of isoflurane in the spinal cord, but both eeg and synaptic recordings provide evidence for effects of isoflurane on these gaba(a)-r isoforms in cortical structures. |
2006-07-06 |
2023-08-12 |
mouse |
| Katherine Saud, Christian Arriagada, Ana María Cárdenas, Takeshi Shimahara, David D Allen, Raúl Caviedes, Pablo Caviede. Neuronal dysfunction in Down syndrome: contribution of neuronal models in cell culture. Journal of physiology, Paris. vol 99. issue 2-3. 2006-06-28. PMID:16646156. |
cell lines derived from cerebral cortex, hippocampus, spinal cord and dorsal root ganglion of ts16 animals show alterations of intracellular ca2+ signals in response to several neurotransmitters (glutamate, acetylcholine, and gaba). |
2006-06-28 |
2023-08-12 |
mouse |
| Rémy Schlichter, Anne Florence Keller, Mathias De Roo, Jean-Didier Breton, Perrine Inquimbert, Pierrick Poisbea. Fast nongenomic effects of steroids on synaptic transmission and role of endogenous neurosteroids in spinal pain pathways. Journal of molecular neuroscience : MN. vol 28. issue 1. 2006-06-27. PMID:16632874. |
we present some of our recent results concerning inhibitory synaptic transmission in lamina ii of the spinal cord and show that endogenous 5alpha-reduced neurosteroids are produced locally in lamina ii and modulate synaptic gamma-aminobutyric acid a(gabaa) receptor function during development, as well as during inflammatory pain. |
2006-06-27 |
2023-08-12 |
Not clear |
| Anne-Emilie Allain, Alexia Baïri, Pierre Meyrand, Pascal Brancherea. Expression of the glycinergic system during the course of embryonic development in the mouse spinal cord and its co-localization with GABA immunoreactivity. The Journal of comparative neurology. vol 496. issue 6. 2006-06-13. PMID:16628621. |
expression of the glycinergic system during the course of embryonic development in the mouse spinal cord and its co-localization with gaba immunoreactivity. |
2006-06-13 |
2023-08-12 |
mouse |
| Anne-Emilie Allain, Alexia Baïri, Pierre Meyrand, Pascal Brancherea. Expression of the glycinergic system during the course of embryonic development in the mouse spinal cord and its co-localization with GABA immunoreactivity. The Journal of comparative neurology. vol 496. issue 6. 2006-06-13. PMID:16628621. |
to understand better the role of glycine and gamma-aminobutyric acid (gaba) in the mouse spinal cord during development, we previously described the ontogeny of gaba. |
2006-06-13 |
2023-08-12 |
mouse |
| M P Engle, M Gassman, K T Sykes, B Bettler, D L Hammon. Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience. vol 138. issue 4. 2006-06-08. PMID:16427742. |
spinal nerve ligation does not alter the expression or function of gaba(b) receptors in spinal cord and dorsal root ganglia of the rat. |
2006-06-08 |
2023-08-12 |
rat |
| María del Carmen García, Edda Adler-Graschinsky, Stella Maris Celuc. Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. European journal of pharmacology. vol 532. issue 1-2. 2006-06-02. PMID:16472800. |
it is proposed that the hypotensive effect of anandamide in urethane-anesthetized rats could involve the release of cgrp followed by the release of gaba in the spinal cord. |
2006-06-02 |
2023-08-12 |
rat |
| Iu A Polina, D V Amakhin, V M Kozhakov, G G Kurchavyĭ, N P Veselki. [Three types of miniature inhibitory potentiaes in the frog spinal cord motoneurons: the possibility of GABA and glycine co-release]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 92. issue 1. 2006-05-10. PMID:16613054. |
[three types of miniature inhibitory potentiaes in the frog spinal cord motoneurons: the possibility of gaba and glycine co-release]. |
2006-05-10 |
2023-08-12 |
Not clear |
| Jan H Baars, Falk von Dincklage, Josephine Reiche, Benno Rehber. Propofol increases presynaptic inhibition of ia afferents in the intact human spinal cord. Anesthesiology. vol 104. issue 4. 2006-05-04. PMID:16571977. |
in vitro studies indicate that the primary molecular targets of propofol in the spinal cord are gamma-aminobutyric acid (gaba) type a receptors. |
2006-05-04 |
2023-08-12 |
human |
| Hong-Mei Zhang, Shao-Rui Chen, Minoru Matsui, Dinesh Gautam, Jürgen Wess, Hui-Lin Pa. Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Molecular pharmacology. vol 69. issue 3. 2006-04-19. PMID:16365281. |
to determine the role of individual machr subtypes in control of synaptic gaba release, spontaneous inhibitory postsynaptic currents (sipscs) and miniature ipscs (mipscs) were recorded in lamina ii neurons using whole-cell recordings in spinal cord slices of wild-type and machr subtype knockout (ko) mice. |
2006-04-19 |
2023-08-12 |
mouse |
| Chuan-Xiu Yang, Han Xu, Ke-Qing Zhou, Meng-Ya Wang, Tian-Le X. Modulation of gamma-aminobutyric acid A receptor function by thiopental in the rat spinal dorsal horn neurons. Anesthesia and analgesia. vol 102. issue 4. 2006-04-13. PMID:16551908. |
these results indicate that thiopental enhances gabaergic inhibitory transmission and suggest that gaba(a) receptors in the spinal cord are a potential target through which thiopental causes immobility and depresses the response to noxious stimuli. |
2006-04-13 |
2023-08-12 |
rat |
| Gareth Hathway, Emily Harrop, Mark Baccei, Suellen Walker, Andrew Moss, Maria Fitzgeral. A postnatal switch in GABAergic control of spinal cutaneous reflexes. The European journal of neuroscience. vol 23. issue 1. 2006-04-06. PMID:16420421. |
here we show a postnatal switch in tonic gaba(a) receptor (gaba(a)r) modulation of cutaneous tactile and nociceptive reflexes from excitation to inhibition, but only in the intact spinal cord. |
2006-04-06 |
2023-08-12 |
rat |
| Kenneth E McCarson, Vanja Duric, Scott A Reisman, Michelle Winter, S J Enn. GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants. Brain research. vol 1068. issue 1. 2006-04-04. PMID:16368079. |
gaba(b) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants. |
2006-04-04 |
2023-08-12 |
rat |
| Kenneth E McCarson, Vanja Duric, Scott A Reisman, Michelle Winter, S J Enn. GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants. Brain research. vol 1068. issue 1. 2006-04-04. PMID:16368079. |
administration of either of two antidepressants used for the treatment of neuropathic pain, amitriptyline (10 mg/kg) and fluoxetine (5 mg/kg), to rats for 7 days modifies gaba(b) receptor function and subunit expression in the lumbar spinal cord. |
2006-04-04 |
2023-08-12 |
rat |
| Kenneth E McCarson, Vanja Duric, Scott A Reisman, Michelle Winter, S J Enn. GABA(B) receptor function and subunit expression in the rat spinal cord as indicators of stress and the antinociceptive response to antidepressants. Brain research. vol 1068. issue 1. 2006-04-04. PMID:16368079. |
the effects of antidepressant administration on gaba(b(1b)) and gaba(b(2)) subunit expression in spinal cord are more variable than for gaba(b(1a)). |
2006-04-04 |
2023-08-12 |
rat |