All Relations between gaba and spinal cord

Publication Sentence Publish Date Extraction Date Species
M Skup, M Wiater, E Górnicka, M Walentynowicz, J Czarkowska-Bauc. Different effect of locomotor exercise on the homogenate concentration of amino acids and monoamines in the rostral and caudal lumbar segments of the spinal cord in the rat. Spinal cord. vol 45. issue 2. 2007-03-27. PMID:16819557. the effect of long-term (4 weeks) moderate locomotor exercise on segmental distribution of glutamate (glu), aspartate, gamma-aminobutyric acid, glycine (gly), serotonin and noradrenaline in the spinal cord of adult rats was investigated. 2007-03-27 2023-08-12 rat
M Beth Zimmer, Harry G Goshgaria. GABA, not glycine, mediates inhibition of latent respiratory motor pathways after spinal cord injury. Experimental neurology. vol 203. issue 2. 2007-03-20. PMID:17046753. gaba, not glycine, mediates inhibition of latent respiratory motor pathways after spinal cord injury. 2007-03-20 2023-08-12 rat
Araceli Diaz-Ruiz, Hermelinda Salgado-Ceballos, Sergio Montes, Valente Maldonado, Luis Tristan, Mireya Alcaraz-Zubeldia, Camilo Río. Acute alterations of glutamate, glutamine, GABA, and other amino acids after spinal cord contusion in rats. Neurochemical research. vol 32. issue 1. 2007-03-13. PMID:17160506. acute alterations of glutamate, glutamine, gaba, and other amino acids after spinal cord contusion in rats. 2007-03-13 2023-08-12 rat
Francesco Furlan, Giuliano Taccola, Micaela Grandolfo, Leonardo Guasti, Annarosa Arcangeli, Andrea Nistri, Laura Ballerin. ERG conductance expression modulates the excitability of ventral horn GABAergic interneurons that control rhythmic oscillations in the developing mouse spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 4. 2007-02-21. PMID:17251434. in the isolated spinal cord in which gaba immunoreactivity and m-erg mrna were colocalized in interneurons, ventral root rhythms evoked by nmda plus 5-hydroxytryptamine were stabilized and synchronized by e4031. 2007-02-21 2023-08-12 mouse
S J Enna, Kenneth E McCarso. The role of GABA in the mediation and perception of pain. Advances in pharmacology (San Diego, Calif.). vol 54. 2007-02-05. PMID:17175808. in addition, gaba neurons and receptors are found in supraspinal sites known to coordinate the perception and response to painful stimuli and this neurotransmitter system has been shown to regulate control of sensory information processing in the spinal cord. 2007-02-05 2023-08-12 Not clear
Joana Ferreira-Gomes, Fani L Neto, José M Castro-Lope. GABA(B2) receptor subunit mRNA decreases in the thalamus of monoarthritic animals. Brain research bulletin. vol 71. issue 1-3. 2007-02-01. PMID:17113954. many studies have implicated gaba(b) receptors in pain transmission mechanisms, especially in the spinal cord. 2007-02-01 2023-08-12 rat
Ayako Takahashi, Atsushi Tokunaga, Hiroki Yamanaka, Takashi Mashimo, Koichi Noguchi, Ichiro Uchid. Two types of GABAergic miniature inhibitory postsynaptic currents in mouse substantia gelatinosa neurons. European journal of pharmacology. vol 553. issue 1-3. 2007-01-24. PMID:17064685. the physiological and pharmacological properties of gamma-aminobutyric acid (gaba)ergic miniature inhibitory postsynaptic currents (mipscs) were investigated in substantia gelatinosa neurons of mouse spinal cord using whole-cell patch clamp recordings. 2007-01-24 2023-08-12 mouse
Shunsuke Yano, Satoshi Kuroda, Hideo Shichinohe, Toshitaka Seki, Takako Ohnishi, Hiroshi Tamagami, Kazutoshi Hida, Yoshinobu Iwasak. Bone marrow stromal cell transplantation preserves gammaaminobutyric acid receptor function in the injured spinal cord. Journal of neurotrauma. vol 23. issue 11. 2007-01-19. PMID:17115913. in the present study, we sought to elucidate whether bmscs express the neuron-specific gamma-aminobutyric acid (gaba) receptor when transplanted into injured spinal cord. 2007-01-19 2023-08-12 rat
Céline Jean-Xavier, Jean-François Pflieger, Sylvie Liabeuf, Laurent Vina. Inhibitory postsynaptic potentials in lumbar motoneurons remain depolarizing after neonatal spinal cord transection in the rat. Journal of neurophysiology. vol 96. issue 5. 2006-12-06. PMID:16807348. gaba and glycine are excitatory in the immature spinal cord and become inhibitory during development. 2006-12-06 2023-08-12 rat
Annika B Malmberg, William T O'Connor, Jeffery C Glennon, Rose Ceseña, Nigel A Calcut. Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats. Brain research. vol 1115. issue 1. 2006-12-04. PMID:16920081. these findings indicate that the selective depression of basal and stimulus-evoked glutamate levels in the spinal cord of diabetic rats occurs in parallel with elevated spinal gaba levels. 2006-12-04 2023-08-12 rat
Christian Grasshoff, Berthold Drexler, Uwe Rudolph, Bernd Antkowia. Anaesthetic drugs: linking molecular actions to clinical effects. Current pharmaceutical design. vol 12. issue 28. 2006-11-30. PMID:17073666. common volatile anaesthetics induce immobility via molecular targets in the spinal cord, including glycine receptors, gaba(a) receptors, glutamate receptors, and trek-1 potassium channels. 2006-11-30 2023-08-12 mouse
Esther Garcia-Nicas, Jennifer M A Laird, Fernando Cerver. GABAA-Receptor blockade reverses the injury-induced sensitization of nociceptor-specific (NS) neurons in the spinal dorsal horn of the rat. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16707718. cumulative doses of two gamma-aminobutyric acid type a (gaba(a))-receptor antagonists, picrotoxin and bicuculline, were administered systemically or applied directly over the spinal cord. 2006-11-08 2023-08-12 rat
Ying-wei Wang, Xiao-ming Deng, Xin-min You, Shu-xiao Liu, Zhi-qi Zha. Involvement of GABA and opioid peptide receptors in sevoflurane-induced antinociception in rat spinal cord. Acta pharmacologica Sinica. vol 26. issue 9. 2006-10-31. PMID:16115369. involvement of gaba and opioid peptide receptors in sevoflurane-induced antinociception in rat spinal cord. 2006-10-31 2023-08-12 rat
Maria Luisa Gelmi, Donato Pocar, Guido Pontremoli, Sara Pellegrino, Ezio Bombardelli, Gabriele Fontana, Antonella Riva, Walter Balduini, Silvia Carloni, Mauro Cimino, Francis Johnso. 3-demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds. Journal of medicinal chemistry. vol 49. issue 18. 2006-10-16. PMID:16942030. the biological activity of the 3-demethoxy-3-glycosylaminothiocolchicines (7) was evaluated on gaba and strychnine-sensitive glycine receptors present in rat brain and spinal cord. 2006-10-16 2023-08-12 rat
Weifeng Song, Siriporn C Chattipakorn, Lori L McMaho. Glycine-gated chloride channels depress synaptic transmission in rat hippocampus. Journal of neurophysiology. vol 95. issue 4. 2006-09-25. PMID:16381810. moreover, the co-localization of glycine and gaba in hippocampal interneurons, similar to spinal cord, brain stem, and cerebellum, suggests that this property is likely to be a general characteristic of inhibitory interneurons throughout the cns. 2006-09-25 2023-08-12 rat
Young Seob Gwak, Huai Yu Tan, Taick Sang Nam, Kwang Se Paik, Claire E Hulsebosch, Joong Woo Lee. Activation of spinal GABA receptors attenuates chronic central neuropathic pain after spinal cord injury. Journal of neurotrauma. vol 23. issue 7. 2006-09-14. PMID:16866624. activation of spinal gaba receptors attenuates chronic central neuropathic pain after spinal cord injury. 2006-09-14 2023-08-12 rat
Jen-Kun Cheng, Lih-Chu Chio. Mechanisms of the antinociceptive action of gabapentin. Journal of pharmacological sciences. vol 100. issue 5. 2006-08-25. PMID:16474201. they include selectively activating the heterodimeric gaba(b) receptors consisting of gaba(b1a) and gaba(b2) subunits, selectively enhancing the nmda current at gabaergic interneurons, or blocking ampa-receptor-mediated transmission in the spinal cord, binding to the l-alpha-amino acid transporter, activating atp-sensitive k(+) channels, activating hyperpolarization-activated cation channels, and modulating ca(2+) current by selectively binding to the specific binding site of [(3)h]gabapentin, the alpha(2)delta subunit of voltage-dependent ca(2+) channels. 2006-08-25 2023-08-12 Not clear
Jozsef Somogy. Functional significance of co-localization of GABA and Glu in nerve terminals: a hypothesis. Current topics in medicinal chemistry. vol 6. issue 10. 2006-08-11. PMID:16787271. experimental data have been accumulating which demonstrate; i) gaba-immunoreactivity in and gaba-release from constitutively gluergic hippocampal mossy fibre terminals, ii) plasticity of the gabaergic phenotype of constitutively gluergic granule cells of the dentate gyrus, iii) expression of gaba(a) receptor gamma(3) subunit in the mossy fibre termination zone in the ca3 subfield, iv) co-labeling of terminals for gaba and glu in the retina, brain stem and spinal cord, and v) functional compatibility of vesicular glu (vglut3) and gaba (viaat) transporters. 2006-08-11 2023-08-12 Not clear
Giambattista Bonanno, Luca Raiteri, Silvio Paluzzi, Simona Zappettini, Cesare Usai, Maurizio Raiter. Co-existence of GABA and Glu transporters in the central nervous system. Current topics in medicinal chemistry. vol 6. issue 10. 2006-08-11. PMID:16787273. release-regulating gaba heterotransporters of the gat-1 type exist on glu nerve terminals in different rodent brain regions including spinal cord. 2006-08-11 2023-08-12 mouse
Giambattista Bonanno, Luca Raiteri, Silvio Paluzzi, Simona Zappettini, Cesare Usai, Maurizio Raiter. Co-existence of GABA and Glu transporters in the central nervous system. Current topics in medicinal chemistry. vol 6. issue 10. 2006-08-11. PMID:16787273. interestingly, the release of glu induced by gaba in spinal cord is dramatically enhanced in a transgenic mouse model of amyotrophic lateral sclerosis and this effect seems to represent the most precocious mechanism that increases extracellular glu concentration, reported to occur in the pathomechanism. 2006-08-11 2023-08-12 mouse