| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wendy Bautista, Justo Aguilar, José Emanuel Loeza-Alcocer, Rodolfo Delgado-Lezam. Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord. The Journal of physiology. vol 588. issue Pt 14. 2010-11-02. PMID:20519320. |
the aim of the present study was to determine if gaba(a) receptors mediating tonic inhibition participate in the modulation of monosynaptic reflex (msr) in the vertebrate spinal cord. |
2010-11-02 |
2023-08-12 |
Not clear |
| Wendy Bautista, Justo Aguilar, José Emanuel Loeza-Alcocer, Rodolfo Delgado-Lezam. Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord. The Journal of physiology. vol 588. issue Pt 14. 2010-11-02. PMID:20519320. |
this long duration inhibition is similar to the one seen in mammalian spinal cord and it is dependent on gaba(a) as it was completely blocked by 20 microm picrotoxin (ptx) or bicuculline (bic) or 1 microm gabazine, simultaneously depressing the dorsal root potential (drp) without msr facilitation. |
2010-11-02 |
2023-08-12 |
Not clear |
| Wendy Bautista, Justo Aguilar, José Emanuel Loeza-Alcocer, Rodolfo Delgado-Lezam. Pre- and postsynaptic modulation of monosynaptic reflex by GABAA receptors on turtle spinal cord. The Journal of physiology. vol 588. issue Pt 14. 2010-11-02. PMID:20519320. |
our results suggest that (1) the turtle spinal cord has a gaba(a) mediated long duration inhibition similar to presynaptic inhibition observed in mammals, (2) gaba(a) receptors located at the motoneurones and primary afferents might produce tonic inhibition of monosynaptic reflex, and (3) gaba(a) receptors modulate motoneurone excitability reducing the probability of spurious and inappropriate activation. |
2010-11-02 |
2023-08-12 |
Not clear |
| Elisa Luccini, Cristina Romei, Silvia Di Prisco, Maurizio Raiteri, Luca Raiter. Ionic dysregulations typical of ischemia provoke release of glycine and GABA by multiple mechanisms. Journal of neurochemistry. vol 114. issue 4. 2010-10-06. PMID:20524963. |
mouse hippocampus and spinal cord synaptosomes, pre-labeled with [(3)h]glycine or [(3)h]gaba, were exposed in superfusion to 50 mm kcl or to 10 microm veratridine. |
2010-10-06 |
2023-08-12 |
mouse |
| G G Kurchavyĭ, N I Kalinina, N P Veselki. [The contribution of glycine and GABA(A) receptors to generation of the inhibitory postsynaptic potentials in the frog spinal cord motoneurones]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 6. 2010-09-30. PMID:20795472. |
[the contribution of glycine and gaba(a) receptors to generation of the inhibitory postsynaptic potentials in the frog spinal cord motoneurones]. |
2010-09-30 |
2023-08-12 |
Not clear |
| G G Kurchavyĭ, N I Kalinina, N P Veselki. [The contribution of glycine and GABA(A) receptors to generation of the inhibitory postsynaptic potentials in the frog spinal cord motoneurones]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 6. 2010-09-30. PMID:20795472. |
the contribution of glycine and gaba(a) receptors to generation of the inhibitory postsynaptic potentials (ipsps) evoked by microstimulation of the inhibitory fibers was studied intracellularly in the motoneurones of the isolated frog spinal cord. |
2010-09-30 |
2023-08-12 |
Not clear |
| Minoru Miyazato, Kimio Sugaya, Seiichi Saito, Michael B Chancellor, William F Goins, James R Goss, William C de Groat, Joseph C Glorioso, Naoki Yoshimur. Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats. The Journal of urology. vol 184. issue 3. 2010-09-13. PMID:20663524. |
we investigated whether replication defective herpes simplex virus vectors encoding genes of glutamic acid decarboxylase, the gamma-aminobutyric acid synthesis enzyme, could suppress detrusor-sphincter dyssynergia in rats with spinal cord injury. |
2010-09-13 |
2023-08-12 |
rat |
| Robert I Westphalen, Jieying Yu, Margarita Krivitski, Ting-Yu Jih, Hugh C Hemming. Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20374421. |
na(v) coupling to transmitter release was determined by measuring the sensitivity of 4-aminopyridine (4ap)-evoked [(3)h]glutamate and [(14)c]gaba release to the specific na(v) blocker tetrodotoxin (ttx) for nerve terminals isolated from rat cerebral cortex, hippocampus, striatum and spinal cord. |
2010-08-06 |
2023-08-12 |
rat |
| Robert I Westphalen, Jieying Yu, Margarita Krivitski, Ting-Yu Jih, Hugh C Hemming. Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20374421. |
however, the efficacies of ttx for inhibition of 4ap-evoked glutamate release were greater than for inhibition of gaba release in all regions except spinal cord. |
2010-08-06 |
2023-08-12 |
rat |
| Cristina Romei, Elisa Luccini, Maurizio Raiteri, Luca Raiter. The GABA B receptor antagonists CGP35348 and CGP52432 inhibit glycine exocytosis: study with GABA B1- and GABA B2-deficient mice. Pharmacological research. vol 61. issue 6. 2010-07-21. PMID:20138995. |
the intrinsic activity of cgp35348 in spinal cord was not prevented by cgp52432, indicating that cgp35348 is not a partial gaba(b) agonist in this experimental system. |
2010-07-21 |
2023-08-12 |
mouse |
| Cristina Romei, Elisa Luccini, Maurizio Raiteri, Luca Raiter. The GABA B receptor antagonists CGP35348 and CGP52432 inhibit glycine exocytosis: study with GABA B1- and GABA B2-deficient mice. Pharmacological research. vol 61. issue 6. 2010-07-21. PMID:20138995. |
in synaptosomes purified from the spinal cord or the hippocampus of mice lacking either the gaba(b1) (gaba(b1-/-) mice) or the gaba(b2) (gaba(b2-/-) mice) subunit, the evoked exocytosis of [(3)h]glycine was no longer inhibited by (-)-baclofen, whereas the intrinsic activity of cgp35348 and cgp52432 was not decreased. |
2010-07-21 |
2023-08-12 |
mouse |
| Anne-Emilie Allain, Louis Ségu, Pierre Meyrand, Pascal Brancherea. Serotonin controls the maturation of the GABA phenotype in the ventral spinal cord via 5-HT1b receptors. Annals of the New York Academy of Sciences. vol 1198. 2010-07-07. PMID:20536936. |
serotonin controls the maturation of the gaba phenotype in the ventral spinal cord via 5-ht1b receptors. |
2010-07-07 |
2023-08-12 |
mouse |
| Anne-Emilie Allain, Louis Ségu, Pierre Meyrand, Pascal Brancherea. Serotonin controls the maturation of the GABA phenotype in the ventral spinal cord via 5-HT1b receptors. Annals of the New York Academy of Sciences. vol 1198. 2010-07-07. PMID:20536936. |
descending bulbo-spinal 5-ht fibers, coming from the caudal medullary cell groups of the raphe nuclei, progressively invade the mouse spinal cord and arrive at lumbar segments at e15.5 when the number of ventral gaba immunoreactive (gaba-ir) interneurons reaches its maximum. |
2010-07-07 |
2023-08-12 |
mouse |
| Richard W Carr, Ruth Sittl, Johannes Fleckenstein, Peter Graf. GABA increases electrical excitability in a subset of human unmyelinated peripheral axons. PloS one. vol 5. issue 1. 2010-05-20. PMID:20098693. |
the neurotransmitter gaba is interesting in this respect because in animal models of neuropathic pain gaba pre-synaptically regulates nociceptive input to the spinal cord. |
2010-05-20 |
2023-08-12 |
human |
| M Miyazato, K Sugaya, W F Goins, D Wolfe, J R Goss, M B Chancellor, W C de Groat, J C Glorioso, N Yoshimur. Herpes simplex virus vector-mediated gene delivery of glutamic acid decarboxylase reduces detrusor overactivity in spinal cord-injured rats. Gene therapy. vol 16. issue 5. 2010-05-12. PMID:19225548. |
we examined whether replication-defective herpes simplex virus (hsv) vectors encoding the 67 kda form of the glutamic acid decarboxylase (gad(67)) gene product, the gamma-aminobutyric acid (gaba) synthesis enzyme, can suppress detrusor overactivity (do) in rats with spinal cord injury (sci). |
2010-05-12 |
2023-08-12 |
rat |
| Karina Sadlaoud, Sabrina Tazerart, Cécile Brocard, Céline Jean-Xavier, Paule Portalier, Frédéric Brocard, Laurent Vinay, Hélène Bra. Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 9. 2010-05-05. PMID:20203195. |
we investigated the effects of a complete neonatal [postnatal day 0 (p0)] spinal cord transection (sct) on the expression of glycine and gaba(a) receptor subunits (glyr and gaba(a)r subunits) in lumbar motoneurons. |
2010-05-05 |
2023-08-12 |
rat |
| Marco Milanese, Simona Zappettini, Emanuela Jacchetti, Tiziana Bonifacino, Chiara Cervetto, Cesare Usai, Giambattista Bonann. In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis. Journal of neurochemistry. vol 113. issue 2. 2010-04-30. PMID:20132478. |
the effect of gaba on glutamate release from astrocytes has been studied in healthy mice and in a murine transgenic model of amyotrophic lateral sclerosis (als), using mouse spinal cord gliosomes labeled with [(3)h]d-aspartate ([(3)h]d-asp). |
2010-04-30 |
2023-08-12 |
mouse |
| Angela Koelsch, Yongjia Feng, David J Fink, Marina Mat. Transgene-mediated GDNF expression enhances synaptic connectivity and GABA transmission to improve functional outcome after spinal cord contusion. Journal of neurochemistry. vol 113. issue 1. 2010-04-30. PMID:20132484. |
transgene-mediated gdnf expression enhances synaptic connectivity and gaba transmission to improve functional outcome after spinal cord contusion. |
2010-04-30 |
2023-08-12 |
Not clear |
| Stefan K Georgiev, Hiroshi Baba, Tatsuro Kohn. Nitrous oxide and the inhibitory synaptic transmission in rat dorsal horn neurons. European journal of pain (London, England). vol 14. issue 1. 2010-04-23. PMID:19261495. |
using whole-cell patch-clamp recording from rat transversal spinal cord slices, we investigated the actions of 50% n(2)o and 0.5% isoflurane (both 0.3 rat mac; minimum alveolar concentration) on exogenously applied gamma-aminobutyric acid (gaba)- and glycine-induced currents in rat dorsal horn lamina ii neurons. |
2010-04-23 |
2023-08-12 |
rat |
| Kenji Seo, Hiroyuki Seino, Hiroyuki Yoshikawa, Andrey B Petrenko, Hiroshi Baba, Naoshi Fujiwara, Genji Someya, Yoshiro Kawano, Takeyasu Maeda, Masato Matsuda, Takashi Kanematsu, Masato Hirat. Genetic reduction of GABA(A) receptor gamma2 subunit expression potentiates the immobilizing action of isoflurane. Neuroscience letters. vol 472. issue 1. 2010-04-22. PMID:20097266. |
immunohistochemistry for gaba(a) receptor subunits demonstrated reduced expression of gamma2 subunits in the spinal cord of the dko mice. |
2010-04-22 |
2023-08-12 |
mouse |