| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nan-Tsing Chiu, Bi-Fang Lee, Tzung Lieh Yeh, Po See Chen, I Hui Lee, Kao Chin Chen, Yen Kuang Yan. Relationship between striatal dopamine transporter availability and sleep quality in healthy adults. Molecular imaging and biology. vol 13. issue 6. 2012-03-15. PMID:20953736. |
to further investigate the role of dopamine (da) in the sleep-wake cycle, we explored the correlation between presynaptic dopamine transporter (dat) availability and sleep quality in healthy volunteers. |
2012-03-15 |
2023-08-12 |
human |
| I Makkonen, H Kokki, J Kuikka, U Turpeinen, R Riikone. Effects of fluoxetine treatment on striatal dopamine transporter binding and cerebrospinal fluid insulin-like growth factor-1 in children with autism. Neuropediatrics. vol 42. issue 5. 2012-03-13. PMID:22015434. |
the present study was undertaken to correlate striatal dopamine transporter (dat) binding and cerebrospinal fluid insulin-like growth factor-1 (csf-igf-1) with clinical response in autistic children (n=13, age 5-16 years) after a 6-month fluoxetine treatment. |
2012-03-13 |
2023-08-12 |
Not clear |
| Bradley J Martin, Bartholomew J Naughton, Keerthi Thirtamara-Rajamani, Daniel J Yoon, Dawn D Han, A Courtney Devries, Howard H G. Dopamine transporter inhibition is necessary for cocaine-induced increases in dendritic spine density in the nucleus accumbens. Synapse (New York, N.Y.). vol 65. issue 6. 2012-03-12. PMID:20936687. |
previously, our lab created a tool that is useful for determining how inhibiting the dopamine transporter (dat) contributes to the effects of cocaine by generating mice that express a cocaine-insensitive dat (dat-ci mice). |
2012-03-12 |
2023-08-12 |
mouse |
| Beth A Smith, Natalie R S Goldberg, Charles K Meshu. Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse. Brain research. vol 1386. 2012-03-12. PMID:21315689. |
we determined the extent of dopamine (da) terminal changes using western immunoblotting [striatal dopamine transporter (dat) and tyrosine hydroxylase (th)] and alterations in the mean number of da cells/section by immunohistochemistry and nissl staining [th-labeled cells and thionin-stained cells in the substantia nigra pars compacta (sn-pc)]. |
2012-03-12 |
2023-08-12 |
mouse |
| Ye Han, Christina E Khodr, Mohan K Sapru, Jyothi Pedapati, Martha C Boh. A microRNA embedded AAV α-synuclein gene silencing vector for dopaminergic neurons. Brain research. vol 1386. 2012-03-12. PMID:21338582. |
in da pc12 cells, neither vector decreased expression of rat snca, tyrosine hydroxylase (th), dopamine transporter (dat) or the vesicular monoamine transporter (vmat). |
2012-03-12 |
2023-08-12 |
human |
| Phillip M Rappold, Mei Cui, Adrianne S Chesser, Jacqueline Tibbett, Jonathan C Grima, Lihua Duan, Namita Sen, Jonathan A Javitch, Kim Tie. Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 51. 2012-03-09. PMID:22143804. |
furthermore, case-control studies report that individuals with genetic variants in the dopamine transporter (dat, slc6a) have a higher pd risk when exposed to pq. |
2012-03-09 |
2023-08-12 |
mouse |
| Phillip M Rappold, Mei Cui, Adrianne S Chesser, Jacqueline Tibbett, Jonathan C Grima, Lihua Duan, Namita Sen, Jonathan A Javitch, Kim Tie. Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 51. 2012-03-09. PMID:22143804. |
however, it remains a topic of debate whether pq can enter dopamine (da) neurons through dat. |
2012-03-09 |
2023-08-12 |
mouse |
| M L Berlanga, D L Price, B S Phung, R Giuly, M Terada, N Yamada, M Cyr, M G Caron, A Laakso, M E Martone, M H Ellisma. Multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons. Brain research. vol 1390. 2012-03-07. PMID:21439946. |
the dopamine transporter knockout (dat ko) mouse is a model of chronic hyperdopaminergia used to study a wide range of neuropsychiatric disorders such as schizophrenia, attention deficit hyperactivity disorder (adhd), drug abuse, depression, and parkinson's disease (pd). |
2012-03-07 |
2023-08-12 |
mouse |
| Steven J O'Dell, Bryan A Galvez, Alexander J Ball, John F Marshal. Running wheel exercise ameliorates methamphetamine-induced damage to dopamine and serotonin terminals. Synapse (New York, N.Y.). vol 66. issue 1. 2012-03-07. PMID:21953518. |
[(125) i]rti-55 binding and autoradiography was used to quantify dopamine transporters (dat), and radioimmunocytochemistry was used to quantify striatal tyrosine hydroxylase (th). |
2012-03-07 |
2023-08-12 |
rat |
| Sarah Hohmann, Nina Schweinfurth, Thorsten Lau, Michael Deuschle, Florian Lederbogen, Tobias Banaschewski, Patrick Schlos. Differential expression of neuronal dopamine and serotonin transporters DAT and SERT in megakaryocytes and platelets generated from human MEG-01 megakaryoblasts. Cell and tissue research. vol 346. issue 2. 2012-03-06. PMID:22006250. |
differential expression of neuronal dopamine and serotonin transporters dat and sert in megakaryocytes and platelets generated from human meg-01 megakaryoblasts. |
2012-03-06 |
2023-08-12 |
human |
| Sarah Hohmann, Nina Schweinfurth, Thorsten Lau, Michael Deuschle, Florian Lederbogen, Tobias Banaschewski, Patrick Schlos. Differential expression of neuronal dopamine and serotonin transporters DAT and SERT in megakaryocytes and platelets generated from human MEG-01 megakaryoblasts. Cell and tissue research. vol 346. issue 2. 2012-03-06. PMID:22006250. |
in the central nervous system, serotonergic and dopaminergic signaling is terminated by the activity of specialized transporter proteins for serotonin (sert) and dopamine (dat). |
2012-03-06 |
2023-08-12 |
human |
| Piotr Tybura, Anna Grzywacz, Agnieszka Samochowiec, Jerzy Samochowie. [Associations between candidate genes with schizophrenia susceptibility and the treatment efficiency]. Psychiatria polska. vol 45. issue 6. 2012-03-06. PMID:22335125. |
we analysed the gene polymorphisms: dopamine receptor--drd2 (taq 1a, in egzon 8,- 141 c ins/del), dopamine transporter--dat, kainate receptor--grik3, serotonine transporter--sert, serotonine receptor--5ht2a, mono amine oxidase a--mao-a, catechol o-methyl transferase--comt. |
2012-03-06 |
2023-08-12 |
Not clear |
| J-W Tian, W-L Jiang, Y Zhong, Q Meng, Y Gai, H-B Zhu, J Hou, Y Xing, Y-X L. Preclinical pharmacology of TP1, a novel potent triple reuptake inhibitor with antidepressant properties. Neuroscience. vol 196. 2012-02-23. PMID:21925241. |
triple reuptake inhibitors (tris) that block the dopamine transporter (dat), norepinephrine transporter (net), and serotonin transporter (sert) are being developed as a new class of antidepressant that may have better efficacy and fewer side effects compared with traditional antidepressants. |
2012-02-23 |
2023-08-12 |
human |
| Rui Cui, Guoliang Zhang, Yunxiao Kang, Qinglong Cheng, Huibing Tan, Huixian Cui, Geming Sh. Amelioratory effects of testosterone propionate supplement on behavioral, biochemical and morphological parameters in aged rats. Experimental gerontology. vol 47. issue 1. 2012-02-22. PMID:22075531. |
thus, in the present study, the open field motor behavior and adhesive tape removal motor performance as well as the expression of tyrosine hydroxylase (th) and dopamine transporter (dat) of nsda system were examined in aged male rats following chronic subcutaneous injections of testosterone propionate (tp). |
2012-02-22 |
2023-08-12 |
rat |
| Jarod Swant, J Shawn Goodwin, Ashley North, Ahmad Abdul Ali, Joyonna Gamble-George, Sanika Chirwa, Habibeh Khoshboue. α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter. The Journal of biological chemistry. vol 286. issue 51. 2012-02-21. PMID:21990355. |
the neuronal plasma membrane dopamine transporter (dat) is essential for the maintenance of da homeostasis in the brain. |
2012-02-21 |
2023-08-12 |
mouse |
| Maura Castelli, Mauro Federici, Silvia Rossi, Valentina De Chiara, Francesco Napolitano, Valeria Studer, Caterina Motta, Lucia Sacchetti, Rosaria Romano, Alessandra Musella, Giorgio Bernardi, Alberto Siracusano, Howard H Gu, Nicola B Mercuri, Alessandro Usiello, Diego Centonz. Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter. The European journal of neuroscience. vol 34. issue 9. 2012-02-17. PMID:22034972. |
as striatal da signalling modulates the endocannabinoid system (ecs), the present study was aimed at investigating cannabinoid cb1 receptor (cb1r) function in a model of adhd obtained by triple point-mutation in the dopamine transporter (dat) gene in mice, making them insensitive to cocaine [dat cocaine-insensitive (dat-ci) mice]. |
2012-02-17 |
2023-08-12 |
mouse |
| Gregory C Hadlock, Chad C Nelson, Anthony J Baucum, Glen R Hanson, Annette E Fleckenstei. Ex vivo identification of protein-protein interactions involving the dopamine transporter. Journal of neuroscience methods. vol 196. issue 2. 2012-02-16. PMID:21291912. |
the dopamine (da) transporter (dat) is a key regulator of dopaminergic signaling as it mediates the reuptake of extrasynaptic da and thereby terminates dopaminergic signaling. |
2012-02-16 |
2023-08-12 |
rat |
| Mark Hallet. Psychogenic parkinsonism. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21458829. |
there are clinical clues that can lead to the correct diagnosis, and laboratory testing with clinical neurophysiology or dat (dopamine transporter) scanning can be helpful as well. |
2012-02-16 |
2023-08-12 |
Not clear |
| Henk W Berendse, Dareia S Roos, Pieter Raijmakers, Richard L Dot. Motor and non-motor correlates of olfactory dysfunction in Parkinson's disease. Journal of the neurological sciences. vol 310. issue 1-2. 2012-02-16. PMID:21705022. |
in 60 pd patients, [(123)i]fp-cit spect scans were available to assess the relationship between upsit scores and striatal dopamine transporter (dat) binding. |
2012-02-16 |
2023-08-12 |
Not clear |
| Yoshiyuki Kasahara, Yosefu Arime, Yumiko Kubo, Asami Fukui, Ichiro Sor. [Neuronal development of the hyperdopaminergic animal model]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 31. issue 5-6. 2012-02-16. PMID:22256607. |
dopamine transporter knockout (dat ko) mice exhibited hyperdopaminergic tone in the nucleus accumbens and striatum, whereas they showed normal levels of extracellular dopamine in the prefrontal cortex. |
2012-02-16 |
2023-08-12 |
mouse |