| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Biju Gopalakrishnan, Joseph H Friedma. Dopamine Transporter Scan (DAT) in Parkinsonism - a Short Review for Non-Neurologists. Rhode Island medical journal (2013). vol 106. issue 8. 2023-08-29. PMID:37643339. |
the dopamine transporter scan (dat) is a radionuclear imaging technique which was approved by the fda to differentiate essential tremor (et) from parkinson's disease (pd). |
2023-08-29 |
2023-09-07 |
Not clear |
| Bruna Rodrigues Gontijo, Isabella Possatti, Caroline Ferreira Fratelli, Alexandre Sampaio Rodrigues Pereira, Larissa Sousa Silva Bonasser, Calliandra Maria de Souza Silva, Izabel Cristina Rodrigues da Silv. The Biomedicines. vol 11. issue 8. 2023-08-26. PMID:37626766. |
the active human dopamine transporter (dat), which is encoded by the |
2023-08-26 |
2023-09-07 |
human |
| Jill Rocchetti, Caroline Fasano, Gregory Dal-Bo, Elisa Guma, Salah El Mestikawy, Tak-Pan Wong, Gohar Fakhfouri, Bruno Giro. Persistent extrasynaptic hyperdopaminergia in the mouse hippocampus induces plasticity and recognition memory deficits reversed by the atypical antipsychotic sulpiride. PloS one. vol 18. issue 8. 2023-08-25. PMID:37624765. |
after verifying the presence of dat-positive neuronal projections in the ventral (temporal), but not in the dorsal (septal), part of the hp, gbr12935, a blocker of dopamine transporter (dat), was infused in the ca1 of adult c57bl/6 mice to produce local hyperdopaminergia. |
2023-08-25 |
2023-09-07 |
mouse |
| Daniele Zanella, Nicholas K Smith, J Andrew Hardaway, Anna Marie Buchanan, Clarence H Mullins, Aurelio Galli, Angela M Carte. Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning. Scientific reports. vol 13. issue 1. 2023-08-17. PMID:37591972. |
psychostimulants target the dopamine transporter (dat) to elicit their psychomotor actions. |
2023-08-17 |
2023-09-07 |
mouse |
| John Stephen Middleton, Hanna Lynn Hovren, Nelson Kha, Manuel Joseph Medina, Karen Ruth MacLeod, Luis Concha-Marambio, Kendal Jay Jense. Seed amplification assay results illustrate discrepancy in Parkinson's disease clinical diagnostic accuracy and error rates. Journal of neurology. 2023-08-17. PMID:37592136. |
blinded cerebrospinal fluid (csf) specimens from a repository that included cohorts of subjects clinically diagnosed as pd or healthy controls, both with confirmatory dopamine transporter single-photon emission computed tomography (dat spect) imaging, and blinded csf specimens from a repository that included cohorts of subjects clinically diagnosed as pd or healthy controls based on clinical diagnosis alone, were tested as part of the validation studies for the diagnostic αsyn-saa test (syntap® biomarker test). |
2023-08-17 |
2023-09-07 |
human |
| Zhaoying Dong, Rui Zuo, Xiaoni Zhong, Changhong Zhang, Xiaoya Zou, Yuan Tian, Hongzhou Zuo, Xinyi Du, Qian Yu, Oumei Chen. Antihypertensive drugs may not delay the symptom progression of Parkinson's disease: A 2-year follow-up study. Heliyon. vol 9. issue 8. 2023-08-10. PMID:37560660. |
the focus of this study was on the changes in dopamine transporter (dat) levels to assess the effect of antihypertensive drugs on the progression of pd. |
2023-08-10 |
2023-08-16 |
Not clear |
| Chongyao Jin, YiQing Jiang, Huihui W. Association between regular physical activity and biomarker changes in early Parkinson's disease patients. Parkinsonism & related disorders. 2023-08-06. PMID:37544865. |
pd-related biomarkers, such as dopamine transporter (dat) imaging and cerebrospinal fluid (csf) α-synuclein (α-syn) and amyloid β (aβ), correlate with disease severity and, to some extent, reflect disease progression and pathology. |
2023-08-06 |
2023-08-14 |
Not clear |
| Florian Koban, Michael Freissmut. The cell cycle protein MAD2 facilitates endocytosis of the serotonin transporter in the neuronal soma. EMBO reports. 2023-08-02. PMID:37530743. |
monoamine transporters retrieve serotonin (sert), dopamine (dat), and norepinephrine (net) from the synaptic cleft. |
2023-08-02 |
2023-08-14 |
Not clear |
| Deepika Suri, Giulia Zanni, Darshini Mahadevia, Nao Chuhma, Rinki Saha, Stephen Spivack, Nicolò Pini, Gregory S Stevens, Annette Ziolkowski-Blake, Eleanor H Simpson, Peter Balsam, Stephen Rayport, Mark S Ansorg. Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression. Molecular psychiatry. 2023-08-02. PMID:37532798. |
in mice, dopamine transporter (dat) blockade from postnatal (p) day 22 to 41 increases aggression and sensitivity to amphetamine (amph) behavioral stimulation in adulthood. |
2023-08-02 |
2023-08-14 |
mouse |
| Deepika Suri, Giulia Zanni, Darshini Mahadevia, Nao Chuhma, Rinki Saha, Stephen Spivack, Nicolò Pini, Gregory S Stevens, Annette Ziolkowski-Blake, Eleanor H Simpson, Peter Balsam, Stephen Rayport, Mark S Ansorg. Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression. Molecular psychiatry. 2023-08-02. PMID:37532798. |
lastly, using optogenetics to drive dopamine neurons, we find that increased vta but not snc dopaminergic activity mimics the increase in impulsive behavior in the go/nogo task observed after adolescent dat blockade. |
2023-08-02 |
2023-08-14 |
mouse |
| Samara Vilca, Claes Wahlestedt, Sari Izenwasser, Raul R Gainetdinov, Marta Pard. Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509143. |
dopamine transporter (dat) transgenic rats recently have been proposed as a new animal model for studying susceptibility to cud. |
2023-07-29 |
2023-08-14 |
rat |
| Mattias Persson, Svante Vikingsson, Robert Kronstrand, Henrik Gree. Characterization of neurotransmitter inhibition for seven cathinones by a proprietary fluorescent dye method. Drug testing and analysis. 2023-07-25. PMID:37489044. |
to start addressing this need, a method measuring the inhibition of the dopamine, serotonin, and norepinephrine transporters (dat, sert, and net) by stimulant drugs was developed. |
2023-07-25 |
2023-08-14 |
Not clear |
| Chao Wang, Cheng Zhou, Tao Guo, Yeerfan Jiaerken, Siyu Yang, Xiaopei Xu, Ling Hu, Peiyu Huang, Xiaojun Xu, Minming Zhan. Current coffee consumption is associated with decreased striatal dopamine transporter availability in Parkinson's disease patients and healthy controls. BMC medicine. vol 21. issue 1. 2023-07-25. PMID:37491235. |
we therefore aim to investigate the role of coffee consumption in nigrostriatal dopaminergic neurodegeneration using dopamine transporter (dat) imaging in pd and healthy controls (hc). |
2023-07-25 |
2023-08-14 |
Not clear |
| Cecilia E Villanueva, Bruno Hagenbuc. Palmitoylation of Solute Carriers. Biochemical pharmacology. 2023-07-22. PMID:37481134. |
among the best-characterized transporters are the glucose transporters glut1 (slc2a1) and glut4 (slc2a4), the three monoamine transporters norepinephrine transporter (net; slc6a2), dopamine transporter (dat; slc6a3), and serotonin transporter (sert; slc6a4), and the sodium-calcium exchanger ncx1 (slc8a1). |
2023-07-22 |
2023-08-14 |
Not clear |
| Navina Suresh, Suvarna Jyothi Kantipudi, Deepika Ramu, Suresh Kumar Muniratnam, Vettriselvi Venkatesa. Association between opioid and dopamine receptor gene polymorphisms OPRM1rs1799971, DAT VNTR9-10 repeat allele, DRD1 rs4532 and DRD2 rs1799732 and alcohol dependence: an ethnicity oriented meta-analysis. Pharmacogenetics and genomics. 2023-07-19. PMID:37466123. |
we carried out a meta-analysis of four opioid and dopamine candidate gene polymorphisms having conflicting results in prior literature, namely oprm1 rs1799971, dat vntr9-10 repeat, drd1 rs4532 and drd2 rs1799732, to clarify their association with alcohol dependence and further stratified results by ethnicity to analyze possible ethnicity-mediated effects. |
2023-07-19 |
2023-08-14 |
Not clear |
| Melinda Hersey, Andy Y Chen, Mattingly K Bartole, Jayati Anand, Amy Hauck Newman, Gianluigi Tand. An FSCV Study on the Effects of Targeted Typical and Atypical DAT Inhibition on Dopamine Dynamics in the Nucleus Accumbens Shell of Male and Female Mice. ACS chemical neuroscience. 2023-07-19. PMID:37466616. |
an fscv study on the effects of targeted typical and atypical dat inhibition on dopamine dynamics in the nucleus accumbens shell of male and female mice. |
2023-07-19 |
2023-08-14 |
mouse |
| Melinda Hersey, Andy Y Chen, Mattingly K Bartole, Jayati Anand, Amy Hauck Newman, Gianluigi Tand. An FSCV Study on the Effects of Targeted Typical and Atypical DAT Inhibition on Dopamine Dynamics in the Nucleus Accumbens Shell of Male and Female Mice. ACS chemical neuroscience. 2023-07-19. PMID:37466616. |
many psychostimulants, like cocaine, inhibit the dopamine transporter (dat), which is largely thought to account for actions related to their misuse and dependence. |
2023-07-19 |
2023-08-14 |
mouse |
| Jonatan Fullerton Støier, Ainoa Konomi-Pilkati, Mia Apuschkin, Freja Herborg, Ulrik Gethe. Amphetamine-induced reverse transport of dopamine does not require cytosolic Ca The Journal of biological chemistry. 2023-07-19. PMID:37468107. |
amphetamine-induced reverse transport of dopamine does not require cytosolic ca amphetamines (amphs) are substrates of the dopamine transporter (dat) and reverse the direction of dopamine (da) transport. |
2023-07-19 |
2023-08-14 |
Not clear |
| L B Kuiper, J B Roberts, P M Estave, D Leo, R R Gainetdinov, S R Jone. Patterns of ethanol intake in male rats with partial dopamine transporter deficiency. Genes, brain, and behavior. 2023-07-18. PMID:37461188. |
growing evidence suggests that alcohol drinking is modulated by the function of the dopamine transporter (dat), which tightly regulates extracellular dopamine concentrations. |
2023-07-18 |
2023-08-14 |
human |
| L B Kuiper, J B Roberts, P M Estave, D Leo, R R Gainetdinov, S R Jone. Patterns of ethanol intake in male rats with partial dopamine transporter deficiency. Genes, brain, and behavior. 2023-07-18. PMID:37461188. |
these findings suggest that partial dat blockade and concomitant increase in brain dopamine levels has potential to reduce drinking and ameliorate alcohol use disorder (aud). |
2023-07-18 |
2023-08-14 |
human |