| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting-Li Tang, Yan Yang, Lin Guo, Shuang Xia, Bikui Zhang, Miao Ya. Sunitinib induced hepatotoxicity in L02 cells Frontiers in pharmacology. vol 13. 2022-11-17. PMID:36386201. |
sunitinib significantly reduced the survival of human normal hepatocytes (l02 cells), induced the increase of alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh). |
2022-11-17 |
2023-08-14 |
human |
| Isabella C Hirako, Maísa Mota Antunes, Rafael Machado Rezende, Natália Satchiko Hojo-Souza, Maria Marta Figueiredo, Thomaz Dias, Helder Nakaya, Gustavo Batista Menezes, Ricardo Tostes Gazzinell. Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections. Scientific reports. vol 12. issue 1. 2022-11-17. PMID:36396745. |
similar to patients, infection with plasmodium chabaudi induced acute liver damage as determined by serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) elevation. |
2022-11-17 |
2023-08-14 |
mouse |
| Abhishek Kumar, Ashish Anjanka. A Narrative Review of Vitamin A Supplementation in Preterm and Term Infants. Cureus. vol 14. issue 10. 2022-11-16. PMID:36381685. |
there were no discernible variations in the occurrence of momentarily increased aspartate aminotransferase (ast), alanine transaminase (alt), or alkaline phosphatase between the leading group and the trace group. |
2022-11-16 |
2023-08-14 |
Not clear |
| Hayder Kadhim Jabbar, Meaad Kadhum Hassan, Lamia Mustafa Al-Naam. Lipids profile in children and adolescents with β-thalassemia major. Hematology, transfusion and cell therapy. 2022-11-15. PMID:36379885. |
complete blood count, serum lipids and ferritin, liver function tests, c-reactive protein (crp), high-sensitivity crp (hs-crp) and serum malondialdehyde (mda) were evaluated results: patients with β-tm had significantly lower hemoglobin (hb), total cholesterol (tc), high-density lipoprotein (hdl), low-density lipoprotein (ldl) and non-high-density lipoprotein (non-hdl) and significantly higher very low-density lipoprotein (vldl), triglycerides (tgs), ldl/hdl ratio, mda, hs-crp, total serum bilirubin (tsb), alanine aminotransferase (alt) and aspartate aminotransferase (ast) than the control group (p < 0.05). |
2022-11-15 |
2023-08-14 |
Not clear |
| Ola Nafea, Fatma Ibrahim, Walaa Abdelhami. The reversed De Ritis ratio for predicting in-hospital mortality among intensive care patients with organophosphate poisoning. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2022-11-15. PMID:36377078. |
this study was designed to explore the prognostic role of on-admission hepatic aminotransferases [alanine aminotransferase (alt) and aspartate aminotransferase (ast), and the reversed de ritis ratio (alt/ast)] in the prediction of in-hospital mortality among patients with acute organophosphate (op) poisoning. |
2022-11-15 |
2023-08-14 |
Not clear |
| Yanfei Wei, Jiansheng Cai, Xiaoting Mo, Min Xu, Qiumei Liu, Junling Zhang, Shuzhen Liu, Yinxia Lin, Shenxiang Huang, Jian Qin, Zhiyong Zhan. Associations of Dietary and Plasma Copper Levels with Liver Function in a Chinese Population. Biological trace element research. 2022-11-12. PMID:36369451. |
a cross-sectional study was performed to assess liver function biomarkers-namely, levels of total bilirubin (tbil), direct bilirubin (dbil), indirect bilirubin (ibil), alanine transaminase (alt), and aspartate transaminase (ast)-in 2376 subjects in guangxi, china. |
2022-11-12 |
2023-08-14 |
human |
| Fazul Nabi, Muhammad Asif Arain, Zohaib Ahmed Bhutto, Qurban Ali Shah, Nasrullah Bangulzai, Nisar Ahmed Ujjan, Sarfaraz Ali Fazlan. Effect of early feeding of L-arginine and L-threonine on hatchability and post-hatch performance of broiler chicken. Tropical animal health and production. vol 54. issue 6. 2022-11-12. PMID:36370219. |
the plasma concentration of aspartate aminotransferase (ast) and alanine aminotransferase (alt) were noted to decrease in arg + thr group. |
2022-11-12 |
2023-08-14 |
chicken |
| Gjin Ndrepepa, Stefan Holdenrieder, Adnan Kastrat. Prognostic Value of De Ritis Ratio with Aspartate Aminotransferase and Alanine Aminotransferase Within the Reference Range. Clinica chimica acta; international journal of clinical chemistry. 2022-11-12. PMID:36370837. |
whether aspartate aminotransferase (ast) to alanine aminotransferase (alt ratio (de ritis ratio) with ast and alt activities within the reference range has prognostic value is unknown. |
2022-11-12 |
2023-08-14 |
Not clear |
| Hany Ezzat Khalil, Miada F Abdelwahab, Hairul-Islam Mohamed Ibrahim, Khalid A AlYahya, Abdullah Abdulhamid Altaweel, Abdullah Jalal Alasoom, Hussein Ali Burshed, Marwan Mohamed Alshawush, Shaimaa Wa. Cichoriin, a Biocoumarin, Mitigates Oxidative Stress and Associated Adverse Dysfunctions on High-Fat Diet-Induced Obesity in Rats. Life (Basel, Switzerland). vol 12. issue 11. 2022-11-11. PMID:36362887. |
triglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), alanine transaminase (alt), aspartate transaminase (ast), creatine kinase mb (ck-mb), urea, creatinine, the hepatic and renal malondialdehyde (mda) as well as reduced glutathione (gsh) levels were assessed. |
2022-11-11 |
2023-08-14 |
rat |
| Shandiz Morega, Andrei Gresita, Smaranda Ioana Mitran, Madalina Iuliana Musat, Ianis Kevyn Stefan Boboc, Victor Gheorman, Ion Udristoiu, Carmen Valeria Albu, Costin Teodor Streba, Bogdan Catalin, Ion Rogovean. Cerebrolysin Use in Patients with Liver Damage-A Translational Study. Life (Basel, Switzerland). vol 12. issue 11. 2022-11-11. PMID:36362945. |
we investigated stroke patients treated with cerebrolysin that presented elevated levels of aspartate aminotransferase (ast) and/or alanine aminotransferase (alt). |
2022-11-11 |
2023-08-14 |
mouse |
| Kim Wai Parn, Wei Chih Ling, Jin Han Chin, Siew-Keah Le. Safety and Efficacy of Dietary Epigallocatechin Gallate Supplementation in Attenuating Hypertension via Its Modulatory Activities on the Intrarenal Renin-Angiotensin System in Spontaneously Hypertensive Rats. Nutrients. vol 14. issue 21. 2022-11-11. PMID:36364864. |
increased alanine aminotransferase (alt), aspartate aminotransferase (ast) and thiobarbituric acid reactive substances (tbars) were evident in shr supplemented with 500 and 1000 mg/kg b.w. |
2022-11-11 |
2023-08-14 |
rat |
| Bálint Drácz, Diána Czompa, Katalin Müllner, Krisztina Hagymási, Pál Miheller, Hajnal Székely, Veronika Papp, Miklós Horváth, István Hritz, Attila Szijártó, Klára Werlin. The Elevated De Ritis Ratio on Admission Is Independently Associated with Mortality in COVID-19 Patients. Viruses. vol 14. issue 11. 2022-11-11. PMID:36366457. |
liver damage in covid-19 patients was documented as increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels or an elevated ast/alt ratio, known as the de ritis ratio. |
2022-11-11 |
2023-08-14 |
Not clear |
| Bangyan Hu, Jin Li, Daoyin Gong, Yuan Dai, Ping Wang, Lihong Wan, Shijun X. Long-Term Consumption of Food-Derived Chlorogenic Acid Protects Mice against Acetaminophen-Induced Hepatotoxicity via Promoting PINK1-Dependent Mitophagy and Inhibiting Apoptosis. Toxics. vol 10. issue 11. 2022-11-10. PMID:36355956. |
the outcomes showed that cga could reduce the activities of serum enzymes such as alanine transaminase (alt), aspartate transaminase (ast), and lactate dehydrogenase (ldh), and alleviate liver injury in mice. |
2022-11-10 |
2023-08-14 |
mouse |
| Siddhartha Sengupta, Nemai Bhattacharya, Anusri Tripath. Increased CRP, anti-CCP antibody, IL-2R, COMP levels in prognosis of post-chikungunya chronic arthritis and protective role of their specific genotypes against arthritic manifestation. Virus research. 2022-11-10. PMID:36356677. |
serum levels of arthritic [crp (c-reactive protein), anti cyclic-citrullinated-peptide (anti-ccp) antibody, soluble interleukin-2 receptor (sil-2r), cartilage oligomeric matrix protein (comp)] and hepatic [alt (alanine aminotransferase), ast (aspartate aminotransferase), alp (alkaline phosphatase), albumin and bilirubin] biomarkers of 167 chikungunya positive patients were determined by sandwich-elisa/immunoturbidimetry/auto-analyser. |
2022-11-10 |
2023-08-14 |
Not clear |
| Xiaotian Zhang, Haibo Yu, Xianfang Yan, Pengju Li, Chi Wang, Cheng Zhang, Hong Ji, Qinfeng Gao, Shuanglin Don. Selenium improved mitochondrial quality and energy supply in the liver of high-fat diet-fed grass carp (Ctenopharyngodon idella) after heat stress. Fish physiology and biochemistry. 2022-11-08. PMID:36348187. |
the results show that selenium significantly prompted the growth, increased glutathione peroxidase (gpx) activity, but reduced malondialdehyde (mda) content in the liver and the levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the serum of grass carp fed with hfd after hs. |
2022-11-08 |
2023-08-14 |
Not clear |
| Reza Rostami, Zahra Eslamifar, Sedighe Nazemi, Seyedeh Zeinab Hosseini, Mohammad Mehdi Behvandi, Leila Jafaripou. The Effect of Thyme Essential Oil on Liver Injuries Caused by Renal Ischemia-Reperfusion in Rats. BioMed research international. vol 2022. 2022-11-07. PMID:36337844. |
animal serum was isolated to evaluate alkaline phosphatase (alp), aspartate aminotransferase (ast), and alanine aminotransferase (alt) parameters. |
2022-11-07 |
2023-08-14 |
rat |
| Yusuke Watanabe, Akihiko Osaki, Nobuo Waguri, Atsunori Tsuchiya, Shuji Tera. Prognostic study of acute-on-chronic liver failure patients: Usefulness of the fibrosis-4 index. Medicine. vol 101. issue 44. 2022-11-07. PMID:36343064. |
in the analysis before acute insults, aspartate aminotransferase (ast), fibrosis-4 (fib-4) index score, and ast to platelet ratio index (apri) showed significant differences between the two groups. |
2022-11-07 |
2023-08-14 |
Not clear |
| Huanfei Ding, Muhammad Fawad, Xiaolin Xu, Bowen H. A framework for identification and classification of liver diseases based on machine learning algorithms. Frontiers in oncology. vol 12. 2022-10-31. PMID:36313630. |
and the important orders of 14 significant risk factors are as follows: total bilirubin, gamma-glutamyl transferase (ggt), direct bilirubin, hemoglobin, age, platelet, alkaline phosphatase (alp), aspartate transaminase (ast), creatinine, alanine aminotransferase (alt), cholesterol, albumin, urea nitrogen, and white blood cells. |
2022-10-31 |
2023-08-14 |
Not clear |
| Ahmed Kamr, Hany Hassan, Ramiro Toribio, Anis Anis, Mohamed Nayel, Ali Arbag. Oxidative stress, biochemical, and histopathological changes associated with acute lumpy skin disease in cattle. Veterinary world. vol 15. issue 8. 2022-10-31. PMID:36313851. |
the objectives of this study were to assess histopathological changes in cattle infected with lsd and measure serum malondialdehyde (mda - oxidant) and total anti-oxidant capacity (tac - anti-oxidant), trace elements (zinc, copper, and iron), cytokines (interleukin [il]-1β, il-6, and tumor necrosis factor-alpha [tnf-α]), haptoglobin (hp), serum amyloid a (saa), aspartate aminotransferase (ast), alanine aminotransferase (alt), creatine phosphokinase (cpk), blood urea nitrogen (bun), and creatinine concentrations. |
2022-10-31 |
2023-08-14 |
cattle |
| Liwan Fu, Yuquan Wang, Yue-Qing H. Association between homocysteine and nonalcoholic fatty liver disease: Mendelian randomization study. European journal of clinical investigation. 2022-10-28. PMID:36305497. |
furthermore, we explored the relationship of hcy with liver enzymes, including alkaline phosphatase (alp), alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2022-10-28 |
2023-08-14 |
Not clear |