| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vasiliki Epameinondas Georgakopoulou, Triada Bali, Magdalini Adamantou, Stavroula Asimakopoulou, Sotiria Makrodimitri, Stamatia Samara, Maria Triantafyllou, Pantazis M Voutsinas, Irene Eliadi, Georgios Karamanakos, Dimitrios Basoulis, Odysseas Chatzipanagiotou, Eleni Adamopoulou, Antonia Alevizou, Menelaos Athanasiadis, Demetrios A Spandidos, Petros Papalexis, Kyriakos Tarantinos, Nikolaos V Sipsas, Michael Samarkos, Evangelos Cholongita. Acute hepatitis and liver injury in hospitalized patients with COVID‑19 infection. Experimental and therapeutic medicine. vol 24. issue 5. 2022-10-24. PMID:36277149. |
these abnormalities are typically manifested as elevations in aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels, with less frequently detected elevations in the levels of cholestatic enzymes. |
2022-10-24 |
2023-08-14 |
Not clear |
| Zahraa Alaaeldein Gadoa, Ahmed Hussein Moustafa, Samir Mohamed El Rayes, Ahmed A Arisha, Mohamed Fouad Mansou. Zinc Oxide Nanoparticles and Synthesized Pyrazolopyrimidine Alleviate Diabetic Effects in Rats Induced by Type II Diabetes. ACS omega. vol 7. issue 41. 2022-10-24. PMID:36278044. |
the results indicated that serum glucose, total cholesterol (tc), triacylglycerol (tg), low-density lipoprotein-cholesterol (ldl-c), very low-density lipoprotein-cholesterol (vldl-c), malondialdehyde, alanine aminotransferase (alt), aspartate aminotransferase (ast), and peroxisome proliferator-activated receptor gamma coactivator 1-alpha pgc-1α mrna expressions were increased in the diabetic group versus the control group, while serum insulin, high-density lipoprotein-cholesterol (hdl-c), superoxide dismutase (sod), and carnitine palmitoyltransferase 1a (cpt1a) mrna expression levels were decreased. |
2022-10-24 |
2023-08-14 |
rat |
| Francesca Falco, Gioacchino Bono, Matteo Cammarata, Jessica Cavalca, Irene Vazzana, Mariano Dara, Danilo Scannella, Stefano Guicciardi, Caterina Faggio, Sergio Ragones. Physiological stress indicators in the plasma of Scyliorhinus canicula captured by botto trawling at two depths. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2022-10-24. PMID:36280133. |
here, we measured the levels of lactate, glucose, alanine amino transferase (alt), aspartate amino transferase (ast), ca |
2022-10-24 |
2023-08-14 |
Not clear |
| Keynaz Keykavousi, Fahimeh Nourbakhsh, Nooshin Abdollahpour, Farzaneh Fazeli, Alireza Sedaghat, Vahid Soheili, Amirhossein Sahebka. A Review of Routine Laboratory Biomarkers for the Detection of Severe COVID-19 Disease. International journal of analytical chemistry. vol 2022. 2022-10-21. PMID:36267156. |
the purpose of this review is to investigate the role of hematological (white blood cell (wbc), lymphocyte, and neutrophil count, neutrophil-to-lymphocyte ratio (nlr), platelet, and red blood cell (rbc) count), inflammatory (c-reactive protein (crp), erythrocyte sedimentation rate (esr), and lactate dehydrogenase (ldh)), and biochemical (albumin, aspartate aminotransferase (ast) and alanine aminotransferase (alt), blood urea nitrogen (bun), creatinine, d-dimer, total cholesterol, low-density lipoprotein (ldl), and high-density lipoprotein (hdl)) biomarkers in the pathogenesis of covid-19 disease and how their levels vary according to disease severity. |
2022-10-21 |
2023-08-14 |
Not clear |
| Omid Asbaghi, Ghazaleh Shimi, Farideh Shiraseb, Ashkan Karbasi, Maryam Nadery, Damoon Ashtary-Larky, Mohammad Zamani, Neda Haghigha. The effects of conjugated linoleic acid supplementation on liver function enzymes and malondialdehyde in adults: A GRADE-assessed systematic review and dose-response meta-analysis. Pharmacological research. 2022-10-21. PMID:36270407. |
this systematic review and meta-analysis was conducted to summarize data from available randomized clinical trials (rcts) on the effect of cla supplementation on alanine aminotransferase (alt), aspartate aminotransferase (ast) and malondialdehyde (mda) in adults. |
2022-10-21 |
2023-08-14 |
Not clear |
| Mohammad Zamani, Damoon Ashtary-Larky, Nadia Hafizi, Fatemeh Naeini, Mahnaz Rezaei Kelishadi, Cain C T Clark, Sayed Hosein Davoodi, Omid Asbagh. The effect of grape products on liver enzymes: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR. 2022-10-20. PMID:36264051. |
we sought to assess the effects of grape intake on liver enzymes, including alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp), in adults. |
2022-10-20 |
2023-08-14 |
human |
| Katrine Holtz Thorhauge, Maja Thiele, Sönke Detlefsen, Ditlev Nytoft Rasmussen, Stine Johansen, Bjørn Staehr Madsen, Steen Antonsen, Lars Melholt Rasmussen, Katrine Prier Lindvig, Aleksander Kra. Serum keratin-18 detects hepatic inflammation and predicts progression in compensated alcohol-associated liver disease. Hepatology communications. 2022-10-20. PMID:36264145. |
all findings were compared with routine liver function tests: aspartate aminotransferase (ast), alanine aminotransferase (alt), and gamma-glutamyltransferase. |
2022-10-20 |
2023-08-14 |
Not clear |
| Tobias Schupp, Kathrin Weidner, Jonas Rusnak, Schanas Jawhar, Jan Forner, Floriana Dulatahu, Lea Marie Brück, Ursula Hoffmann, Thomas Bertsch, Christel Weiß, Ibrahim Akin, Michael Behne. Diagnostic and prognostic value of the AST/ALT ratio in patients with sepsis and septic shock. Scandinavian journal of gastroenterology. 2022-10-19. PMID:36259154. |
the study investigates the diagnostic and prognostic value of the aspartate aminotransferase (ast) to alanine aminotransferase (alt) ratio in patients with sepsis and septic shock. |
2022-10-19 |
2023-08-14 |
Not clear |
| Lei Qiao, Xina Dou, Xiaofan Song, Jiajing Chang, Shanyao Pi, Xinyi Zhang, Lixu Zhu, Xiaonan Zeng, Chunlan X. Protective effect of biogenic selenium nanoparticles against diquat-induced acute toxicity via regulation of gut microbiota and its metabolites. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-10-18. PMID:36257488. |
the results showed that dietary supplementation with senps attenuated diquat-induced acute toxicity in mice, as demonstrated by lower levels of inflammatory effector cells, and biochemical markers in serum such as aspartate aminotransferase (ast), alanine aminotransferase (alt), blood urea nitrogen (bun) and lactate dehydrogenase (ldh). |
2022-10-18 |
2023-08-14 |
mouse |
| Jian-Nan Zhang, Yang Gao, Xin-Tong Wang, Na-Na Li, Xue Du, Yu-Jia Tang, Qi-Qi Lai, Peng-Fei Chen, Chuang-Shi Yue, Ji-Han Wu, Kai Kang, Ming-Yan Zha. Lymphocyte-C-reactive protein ratio can differentiate disease severity of COVID-19 patients and serve as an assistant screening tool for hospital and ICU admission. Frontiers in immunology. vol 13. 2022-10-17. PMID:36248811. |
demographic and clinical data including gender, age, comorbidities, severity of covid-19, white blood cell count (wbc), neutrophil proportion (neut%), lymphocyte count (lymph), lymphocyte percentage (lym%), red blood cell distribution width (rdw), platelet (plt), c-reactive protein (crp), alanine aminotransferase (alt), aspartate aminotransferase (ast), serum creatinine (scr), albumin (alb), total bilirubin (tb), direct bilirubin (dbil), indirect bilirubin (ibil), and d-dimer were obtained and collated from medical records at admission, from which sequential organ failure assessment (sofa) score and lcr were calculated, and all the above indicators were compared among the groups. |
2022-10-17 |
2023-08-14 |
Not clear |
| Fen Zhang, Linxiao Fan, Qiuhong Liu, Shima Tang, Sainan Zhang, Lanlan Xiao, Lingjian Zhang, Qian Li, Nueraili Maihemuti, Lanjuan L. Comprehensive immune cell analysis of human menstrual-blood-derived stem cells therapy to concanavalin A hepatitis. Frontiers in immunology. vol 13. 2022-10-17. PMID:36248904. |
the serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels and h&e staining depicted that menscs treatment could significantly alleviate cona-induced hepatitis. |
2022-10-17 |
2023-08-14 |
mouse |
| Thomas Minor, Charlotte von Horn, Hristo Zlatev, Fuat Saner, Melanie Grawe, Bastian Lüer, Eva-Maria Huessler, Nils Kuklik, Andreas Pau. Controlled oxygenated rewarming as novel end-ischemic therapy for cold stored liver grafts. A randomized controlled trial. Clinical and translational science. 2022-10-17. PMID:36251938. |
primary outcome mean peak aspartate aminotransferase (ast) was 1371 u/l (sd 2871) after scs versus 767 u/l (sd 1157) after cor (p = 0.273). |
2022-10-17 |
2023-08-14 |
Not clear |
| Jinjin Li, Jie Li, Hongbo Fang, Hang Yang, Tianchun Wu, Xiaoyi Shi, Chun Pan. Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress. International immunopharmacology. vol 113. issue Pt A. 2022-10-17. PMID:36252482. |
the results showed that iso reduced serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, liver necrosis, inflammatory factors il-1β, il-6, mcp-1, and tnf-α expression, mpo |
2022-10-17 |
2023-08-14 |
mouse |
| Muhammad Imran Qayyum, Sami Ullah, Umer Rashid, Abdul Sadiq, Obaidullah, Mater H Mahnashi, Osama M Alshehri, Mohammed M Jalal, Khalid J Alzahrani, Ibrahim F Halawan. Synthesis, Molecular Docking, and Preclinical Evaluation of a New Succinimide Derivative for Cardioprotective, Hepatoprotective and Lipid-Lowering Effects. Molecules (Basel, Switzerland). vol 27. issue 19. 2022-10-14. PMID:36234730. |
toxicity induced by 5-fu was manifested by increases in the serum creatinine kinase myocardial band (ck-mb), troponin i (ctni) and lactate dehydrogenase (ldh), lipid profile, and selected liver enzymes, including alp (alkaline phosphatase), alt (alanine transaminase), ast (aspartate aminotransferase), bt (bilirubin total), and bd (direct bilirubin). |
2022-10-14 |
2023-08-14 |
human |
| Johnafaye Mariano, George A MacLare. A Case of Rhabdomyolysis in a Young, Morbidly Obese, Asthmatic Woman With COVID-19. Cureus. vol 14. issue 9. 2022-10-14. PMID:36237756. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), and creatine kinase (ck) levels were noted to be elevated. |
2022-10-14 |
2023-08-14 |
Not clear |
| b' Aleksandar Antonijevi\\xc4\\x87, Emilija Stojanovi\\xc4\\x87, Aleksandar Jevti\\xc4\\x87, Vladimir \\xc5\\xbdivkovi\\xc4\\x87, Sergey Bolevich, Vladimir Jakovljevi\\xc4\\x8. The effect of a 6-month walking program on biochemical parameters in sedentary adults with type 2 diabetes mellitus. Nagoya journal of medical science. vol 84. issue 3. 2022-10-14. PMID:36237879.' |
plasma glucose, triglyceride, total cholesterol, low-density lipoprotein cholesterol (ldl), high-density lipoprotein cholesterol (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transferase, urea, creatinine, uric acid, c-reactive protein (crp), and erythrocyte sedimentation rate were measured. |
2022-10-14 |
2023-08-14 |
Not clear |
| Manman Duan, Xuanjun Guo, Xiangguang Chen, Mengyu Guo, Mengna Zhang, Hao Xu, Chengju Wang, Yang Yan. Transcriptome analysis reveals hepatotoxicity in zebrafish induced by cyhalofop‑butyl. Aquatic toxicology (Amsterdam, Netherlands). vol 252. 2022-10-14. PMID:36240591. |
meanwhile, the activities of enzymes related to liver function were significantly increased by 0.2 mg/l cyhalofop‑butyl and higher, such as alanine transaminase (alt) and aspartate transaminase (ast). |
2022-10-14 |
2023-08-14 |
zebrafish |
| Mahsa Rastegar Moghaddam Poorbagher, Ehsan Karimi, Ehsan Oskoueia. Hepatoprotective effect of nanoniosome loaded Myristica fragrans phenolic compounds in mice-induced hepatotoxicity. Journal of cellular and molecular medicine. 2022-10-13. PMID:36226354. |
in addition, the blood levels of triglyceride (tg), cholesterol (chol), liver enzymes (aspartate aminotransferase (ast), alanine transaminase (alt), alkaline phosphatase (alp)) and total bilirubin were significantly (p ≤ 0.05) decreased. |
2022-10-13 |
2023-08-14 |
mouse |
| Reham Hassan, Daniela González, Zaynab Hobloss, Lisa Brackhagen, Maiju Myllys, Adrian Friebel, Abdel-Latif Seddek, Rosemarie Marchan, Benedikt Cramer, Hans-Ulrich Humpf, Stefan Hoehme, Gisela H Degen, Jan G Hengstler, Ahmed Ghalla. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Archives of toxicology. 2022-10-13. PMID:36227364. |
the blood biomarkers of liver damage, alanine transaminase (alt) and aspartate transaminase (ast) both increased > 21- and 30-fold, respectively, when ota was administered to abt pre-treated mice compared to the effect of ota alone. |
2022-10-13 |
2023-08-14 |
mouse |
| Tung Huynh, Stephanie Ma, Ke-Qin H. HCV direct acting antiviral treatment leads to highly durable rates of ALT and AST lower than 30/19 criteria and improved APRI and FIB-4 scores. Hepatology communications. 2022-10-12. PMID:36221305. |
direct acting antiviral treatment (daa) has been the standard of care for hepatitis c virus (hcv) infection, but its long-term benefits in alanine aminotransferase (alt) and aspartate aminotransferase (ast) improvement and hepatic fibrosis assessed by aspartate aminotransferase-to-platelet ratio index (apri) and fibrosis-4 index (fib-4) scores remain unknown. |
2022-10-12 |
2023-08-14 |
Not clear |