| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nino Lomtadze, Elene Giorgadze, Shota Janjgava, Tinatin Kacharava, Iamze Taboridz. "The relationship between Insulin Resistance and Thyroid Volume in Georgia". Endocrine, metabolic & immune disorders drug targets. 2023-02-24. PMID:36825717. |
the factors studied were age, sex, body mass index (bmi), clinical signs, thyroid ultrasound, alanine aminotransferase (alt), aspartate aminotransferase (ast), lipids, fasting insulin, fasting glucose, thyroid stimulating hormone (tsh), free thyroxine (ft4), and zinc (zn). |
2023-02-24 |
2023-08-14 |
Not clear |
| Selim Çomaklı, Selçuk Özdemir, Sefa Küçükler, Fatih M Kandemi. Beneficial effects of quercetin on vincristine-induced liver injury in rats: Modulating the levels of Nrf2/HO-1, NF-kB/STAT3, and SIRT1/PGC-1α. Journal of biochemical and molecular toxicology. 2023-02-22. PMID:36808657. |
the results showed that vcr significantly increased the activity of alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp) enzymes. |
2023-02-22 |
2023-08-14 |
rat |
| Dong Luo, Qingmei Pan, Linlin Wang, Wenfeng Zhao, Wentao Ba. Effects of Alprostadil Combined with Edaravone on Inflammation, Oxidative Stress and Pulmonary Function in Patients with Traumatic Hemorrhagic Shock. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 8. 2023-02-21. PMID:36800822. |
24 hours (h) after resuscitation, venous blood were collected to detect serum biochemical indicators such as blood urea nitrogen (bun), aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2023-02-21 |
2023-08-14 |
Not clear |
| Arun J Sanyal, Patricia Lopez, Eric J Lawitz, Kathryn J Lucas, Juergen Loeffler, Won Kim, George B B Goh, Jee-Fu Huang, Carla Serra, Pietro Andreone, Yi-Cheng Chen, Stanley H Hsia, Vlad Ratziu, Diego Aizenberg, Hiroshi Tobita, Aasim M Sheikh, John M Vierling, Yoon Jun Kim, Hideyuki Hyogo, Dean Tai, Zachary Goodman, Felicity Schaefer, Ian R I Carbarns, Sophie Lamle, Miljen Martic, Nikolai V Naoumov, Clifford A Bras. Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial. Nature medicine. 2023-02-16. PMID:36797481. |
the primary endpoints were safety and tolerability to end-of-study, and dose response on alanine aminotransferase (alt), aspartate aminotransferase (ast) and hepatic fat fraction (hff) at week 12. |
2023-02-16 |
2023-08-14 |
Not clear |
| Jennifer Kang, Harishankar Gopakumar, Srinivas R Pul. Prevalence of Osteoporosis in Cirrhosis: A Systematic Review and Meta-Analysis. Cureus. vol 15. issue 1. 2023-02-15. PMID:36788896. |
pooled levels of liver biochemistries were: bilirubin 3.04 mg/dl (95% ci: 2.84-3.25), aspartate aminotransferase (ast) 65.35 u/l (95% ci: 61.39-69.31), alanine aminotransferase (alt) 50.17 u/l (95% ci: 46.18-54.10), alkaline phosphatase 133.31 u/l (95% ci: 124.89-141.73), and albumin 3.25 g/dl (95% ci: 3.05-3.45). |
2023-02-15 |
2023-08-14 |
Not clear |
| E S Abdel-Baky, S A Radwan, M F Ibrahim, O N Abdel-Rahma. Influence of omega- 3 fatty acids, soya isoflavones and their combination for abrogating carbon tetrachloride hazards in male rats. Brazilian journal of biology = Revista brasleira de biologia. vol 84. 2023-02-15. PMID:36790295. |
results showed that ccl4 administration induces hepatic damage indicated by a significant increase in the activities of alkaline phosphatase (alp), aspartate aminotransferase (ast) and aalanine aminotransferase (alt) enzymes and glucose level, with a significant increase in malondialdehyde (mda) and nitric oxide (no) levels and a significant decrease of reduced glutathione (gsh) level in liver tissue. |
2023-02-15 |
2023-08-14 |
rat |
| Bingyong Mao, Weiling Guo, Xuemei Liu, Shumao Cui, Qiuxiang Zhang, Jianxin Zhao, Xin Tang, Hao Zhan. Potential Probiotic Properties of Blautia producta Against Lipopolysaccharide-Induced Acute Liver Injury. Probiotics and antimicrobial proteins. 2023-02-15. PMID:36790661. |
b. producta d4 and dsm2950 pretreatment decreased the activities of serum aspartate transferase (ast), and alanine transaminase (alt) in mice with lps treatment significantly decreased the levels of inflammatory tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β), and interleukin-6 (il-6) and increased the activities of antioxidative superoxide dismutase (sod), catalase (cat), and glutathione peroxidase (gsh-px). |
2023-02-15 |
2023-08-14 |
mouse |
| Chunlan Shan, Deyuan Ou, Yanling Xiong, Hongsong Cheng, Chun Song, Mei Li, Tian Fang, Zhentao Cheng, Fujun Mia. Molecular mechanism of anti-inflammatory effects of the proteasome inhibitor MG-132 on Con A-induced acute liver injury in mice. Research in veterinary science. vol 156. 2023-02-15. PMID:36791578. |
the results showed that the serum activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast) and tnf-α and il-6 contents of mice in the high and medium dose groups were reduced compared with those in the ali group. |
2023-02-15 |
2023-08-14 |
mouse |
| X Y Zeng, Y Zhang, G Tian, K Y Zhang, S P Bai, X M Ding, J P Wang, L Lv, Y Xuan, Y P Liao, Q F Zen. Effects of supplemented mode of emulsifier on growth performance, serum biochemical index, quality of meat and skin fat, and nutrient utilization in Pekin ducks. Poultry science. vol 102. issue 4. 2023-02-12. PMID:36774710. |
additionally, the utilization of dietary dry matter (dm), ether extract (ee), and total phosphorous (tp) were increased, but the activity of aspartate aminotransferase (ast) in serum was decreased in the pree group compared to those in the nc group (p < 0.05). |
2023-02-12 |
2023-08-14 |
Not clear |
| Rui Zhang, Zhigang Zhao, Mingshuai Li, Liang Luo, Shihui Wang, Kun Guo, Wei X. Effects of saline-alkali stress on the tissue structure, antioxidation, immunocompetence and metabolomics of Eriocheir sinensis. The Science of the total environment. 2023-02-12. PMID:36775159. |
the results confirmed the hepatopancreas damage through tissue sectioning, abnormal enzyme activity (aspartate transaminase (ast), alanine aminotransferase (alt)) and aberrant malondialdehyde (mda) content. |
2023-02-12 |
2023-08-14 |
cat |
| Jianzhong Hu, Songqing Zhou, Suryeon Ryu, Kaitlyn Adams, Zan Ga. Effects of Long-Term Endurance Exercise on Cardiac Morphology, Function, and Injury Indicators among Amateur Marathon Runners. International journal of environmental research and public health. vol 20. issue 3. 2023-02-11. PMID:36767963. |
among myocardial injury indicators, serum levels of cardiac troponin i, creatine kinase (ck), creatine kinase-mb (ck-mb), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), and n-terminal pro-b-type natriuretic peptide (nt-probnp) measured before the race, immediately after the race, and 24 h after the race displayed similar trends in changes among ck, ck-mb, ldh, and ast, while nt-probnp levels did not change. |
2023-02-11 |
2023-08-14 |
human |
| Wenjie Li, Xingzhou Jiang, Haisheng Qian, Xinyan Li, Jing Su, Guoxin Zhang, Xuan L. Associations of arsenic exposure with liver injury in US adults: NHANES 2003-2018. Environmental science and pollution research international. 2023-02-08. PMID:36754906. |
we selected alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transferase (ggt), total protein (tp), alt/ast, total bilirubin (tbil), and albumin (alb) as markers of liver injury. |
2023-02-08 |
2023-08-14 |
Not clear |
| Lu Zhang, Xiaoyue Bi, Xiaoxue Chen, Luxue Zhang, Qiqiu Xiong, Weihua Cao, Yanjie Lin, Liu Yang, Tingting Jiang, Wen Deng, Shiyu Wang, Shuling Wu, Ruyu Liu, Yuanjiao Gao, Ge Shen, Min Chang, Hongxiao Hao, Mengjiao Xu, Leiping Hu, Yao Lu, Minghui Li, Yao Xi. A nomogram based on HBeAg, AST, and age to predict non-minimal liver inflammation in CHB patients with ALT <80 U/L. Frontiers in immunology. vol 13. 2023-02-06. PMID:36741383. |
the aim of this study was to develop and validate a nomogram model for the prediction of non-minimal liver inflammation based on liver pathological injuries combined with age and alanine aminotransferase (alt), aspartate aminotransferase (ast), hepatitis b surface antigen (hbsag), hbeag, and hbv dna quantification. |
2023-02-06 |
2023-08-14 |
Not clear |
| Shohreh Nasiri Poroj, Mohammad Reza Fazeli, Mohaddeseh Larypoor, Farid Shariatmadar. Developing a new biologic toxin binder for reducing AFB1 toxicity in laying hens. Letters in applied microbiology. 2023-02-06. PMID:36746433. |
weight changes, serum levels of albumin, globulin, total protein, aspartate transaminase (ast), and alanine transaminase (alt) were measured over 14 days. |
2023-02-06 |
2023-08-14 |
Not clear |
| Melike Karayakali, Eyup Altinoz, Hulya Elbe, Oguzhan Koca, Melike Ozgul Onal, Yasemin Bicer, Mehmet Demi. Crocin treatment exerts anti-inflammatory and anti-oxidative effects in liver tissue damage of pinealectomized diabetic rats. Environmental science and pollution research international. 2023-02-06. PMID:36746856. |
crocin decreased the markers (alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), interleukin-1β (il-1β), and malondialdehyde (mda)) of liver damage and increased antioxidant enzyme levels and tissue total antioxidant status. |
2023-02-06 |
2023-08-14 |
rat |
| Catherine R Foreman-Hesterberg, Jonathan H Forema. Plasma creatine kinase and aspartate aminotransferase activities before, during, and after 5 days of intramuscular penicillin administration in sedentary horses. Journal of equine veterinary science. 2023-02-03. PMID:36736501. |
muscle damage can result in leakage of intracellular enzymes such as creatine kinase (ck) and aspartate transaminase (ast) into plasma. |
2023-02-03 |
2023-08-14 |
Not clear |
| Daram Yang, Jong Won Kim, Hyuneui Jeong, Min Seok Kim, Chae Woong Lim, Kyuhong Lee, Bumseok Ki. Effects of maternal cigarette smoke exposure on the progression of nonalcoholic steatohepatitis in offspring mice. Toxicological research. vol 39. issue 1. 2023-02-02. PMID:36726830. |
maternal mscs exposure increased the severity of nash by increasing serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, hepatic total cholesterol (tc) and triglyceride (tg) levels, pro-inflammation, fibrosis, and steatosis in offspring mice. |
2023-02-02 |
2023-08-14 |
mouse |
| Amr A Gabr, Mona E Farag, Gamal F Shahin, Essam M El-Kotam. Impact of protein supply on the productive performance of growing lambs drinking natural saline water and fed low-quality forage under semi-arid conditions. Tropical animal health and production. vol 55. issue 1. 2023-02-01. PMID:36723688. |
the hs water decreased (p < 0.001) the serum concentrations of alanine aminotransferase (alt) and aspartate aminotransferase (ast) and increased (p = 0.03) the urea-n by about 9%. |
2023-02-01 |
2023-08-14 |
Not clear |
| Jun-Ju Zou, Hong Li, Min Zhou, Qiu-Qing Huang, Yong-Jun Wu, Rong Y. [Zuogui Jiangtang Qinggan Prescription promotes recovery of intestinal mucosal barrier in mice with type 2 diabetes mellitus and nonalcoholic fatty liver disease by improving intestinal flora homeostasis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 2. 2023-02-01. PMID:36725242. |
it down-regulated the serum biomarkers of liver function and dyslipidemia such as alanine aminotransferase(alt), aspartate transaminase(ast), and triglycerides(tg), increased insulin sensitivity, and improved glucose tolerance. |
2023-02-01 |
2023-08-14 |
mouse |
| Mei-Lin Chen, Zhi-Qi Li, Qi-Qi Fan, Si-Min Guo, Qiong Cai, Rui-Chao Lin, Jia-Rui Wu, Chong-Jun Zha. [Hepatotoxicity and mechanism of Rhododendri Mollis Flos based on zebrafish model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 1. 2023-02-01. PMID:36725266. |
meanwhile, the activities of alanine aminotransferase(alt) and aspartate aminotransferase(ast) were determined to confirm the hepatotoxicity of rmf. |
2023-02-01 |
2023-08-14 |
zebrafish |