| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Evelyn Ferri, Paolo D Rossi, Martina Scichilone, Tiziano A Lucchi, Beatrice Arosi. Liver Enzymes in a Cohort of Community-Dwelling Older Persons: Focus on Sex Contribution. Nutrients. vol 14. issue 23. 2022-12-11. PMID:36501002. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) concentrations, and the ast/alt ratio were used to assess liver function in 419 older adults (248 persons with dementia and 171 age- and sex-matched subjects without cognitive decline). |
2022-12-11 |
2023-08-14 |
human |
| Yujie Zhong, Zhiman Li, Ruyi Jin, Yanpeng Yao, Silan He, Min Lei, Xin Wang, Chao Shi, Li Gao, Xiaoli Pen. Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats. Nutrients. vol 14. issue 23. 2022-12-11. PMID:36501024. |
dio decreased hepatic injury markers, including aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2022-12-11 |
2023-08-14 |
rat |
| Imran Sohail, Naila Malkani, Nimra Tahir, Ateeb Khalil, Rukset Attar, Sidra Mumta. Silymarin protects the liver from α-naphthylisothiocyanate-induced cholestasis by modulating the expression of genes involved in bile acid homeostasis. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 7. 2022-12-10. PMID:36495494. |
serum levels of bilirubin, aspartate transaminase (ast), alanine transaminase (alp), and liver histology were analyzed. |
2022-12-10 |
2023-08-14 |
mouse |
| Zhihui Liang, Liang Li, Liming Cao, Jianyu Liu, Jinglei Li. Analyses on Clinical Efficacy of TIPS in the Treatment of Cirrhotic Portal Hypertension and Relevant Influencing Factors. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 7. 2022-12-10. PMID:36495507. |
blood was collected from patients to detect liver function indicators [aspartate aminotransferase (ast) and alanine aminotransferase (alt)], renal function indicators [blood urea nitrogen (bun) and creatinine (cr)], glucose metabolism indicators [insulin and glucose (glu)] and inflammatory factors [interleukin-6 (il-6), il-8 and cxcl9] before surgery and at1 and 6 month(s) after surgery. |
2022-12-10 |
2023-08-14 |
Not clear |
| Shujuan Guo, Juan Zheng, Guimei L. Effects of growth hormone on lipid metabolism and sexual development in pubertal obese male rats. Open life sciences. vol 17. issue 1. 2022-12-07. PMID:36474704. |
after 4 weeks, we measured the levels of alanine transaminase (alt), aspartate aminotransferase (ast), total cholesterol (tc), triglycerides (tgs), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), estrogen (e2), testosterone (t), and insulin-like growth factor (igf-1). |
2022-12-07 |
2023-08-14 |
rat |
| Jyoti E John, Dnyanesh B Amle, Roshan Takhelmayum, Niranjan Gopal, Meena Mishra, Prashant Joshi, Bharatsing Rathod, Rasika Gadkar. Association of COVID-19 Real-Time Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Cycle Threshold Value With Surrogate Markers of Disease Severity. Cureus. vol 14. issue 11. 2022-12-07. PMID:36475201. |
levels of inflammatory markers such as aspartate aminotransferase (ast), ferritin, d-dimer, high sensitivity c-reactive protein (hs-crp), and lactate dehydrogenase (ldh) are used as quantitative measures of covid-19 severity. |
2022-12-07 |
2023-08-14 |
human |
| Yu-Ru Li, Ya-Fang Zhao, Guo-Liang Cheng, En-Li Wang, Yu-Jun Tan, Jing-Chun Yao, Yan Zhao, Gui-Min Zhan. [Therapeutic effect of Jingfang Granules on CCl_4-induced liver fibrosis in mice and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 22. 2022-12-06. PMID:36471937. |
the levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), total bile acid(tba), and triglyceride(tg) in the serum of mice were detected by an automated analyzer. |
2022-12-06 |
2023-08-14 |
mouse |
| Jing Lou, Lei Zhao, Yan-Jie Zhu, Shuai-Qiang Yuan, Fei Wang, Hang-Zhou Zhang, Jiao-Jiao Xu, Xiao-Ke Yu, Liu-Fa Ho. [Study on protective effect of Chaihu Shugan Powder against liver injury in rats with intrahepatic cholestasis by regulating FXR/Nrf2/ARE pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 20. 2022-12-06. PMID:36471979. |
aeroset chemistry analyzer was employed to detect the levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), total bilirubin(tbil), and total bile acid(tba) in rat serum. |
2022-12-06 |
2023-08-14 |
rat |
| Feng-Jing-Ming Cheng, Jian Lyu, Yan-Ming Xi. [Systematic review and Meta-analysis of efficacy and safety of Ganshuang Granules in treatment of liver injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 21. 2022-12-06. PMID:36472014. |
the results of meta-analysis showed that ganshuang granules combined with conventional therapy was superior to the therapy in the control group in reducing alanine aminotransferase(alt)(md=-24.12, 95%ci[-32.17,-16.07], p<0.000 01), aspartate aminotransferase(ast)(md=-23.24, 95%ci[-29.70,-16.78], p<0.000 01), total bilirubin(tbil)(md=-12.42, 95%ci[-14.62,-10.22], p<0.000 01), and gamma-glutamyl transpeptidase(ggt)(md=-21.32, 95%ci[-33.61,-9.03], p=0.000 7). |
2022-12-06 |
2023-08-14 |
Not clear |
| Hui-Min Sun, Ting Zhang, Zhen-Yu Li, Xue-Mei Qi. [Toxicity comparison of raw and vinegar-processed Bupleuri Radix based on ~1H-NMR metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 19. 2022-12-06. PMID:36472029. |
the results showed that, as compared with the control group, alanine aminotransferase(alt), aspartate aminotransferase(ast), and alkaline phosphatase(alp) in the raw br group were increased significantly, while alt and alp in the r-vpbr and s-vpbr groups were significantly decreased(p<0.05), which indicated that br showed certain hepatotoxicity, and vinegar processing reduced its hepatotoxicity. |
2022-12-06 |
2023-08-14 |
rat |
| Wen-Zhang Dai, Zhao-Fang Bai, Ting-Ting He, Xiao-Yan Zhan, Qiang Li, Jing Zhao, Xiao-He Xia. [Schisandrin C improves acetaminophen-induced liver injury in mice by regulating Nrf2 signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 19. 2022-12-06. PMID:36472037. |
in the apap-induced liver injury mouse model, we found that sinc can relieve hepatic histopathological lesions and significantly reduce the activities of alanine aminotransferase(alt), aspartate aminotransferase(ast) and alkaline phosphatase(alp). |
2022-12-06 |
2023-08-14 |
mouse |
| Yulia Khruleva, Zhanna Kobalava, Olga Arisheva, Marina Efremovtseva, Irina Garmash, Maria Vatsik-Gorodetskaya, Mohammed Al Jarallah, Peter A Brady, Ibrahim Al-Zakwani, Rajesh Raja. Clinical Outcome and Risk Assessment in Hospitalized COVID-19 Patients with Elevated Transaminases and Acute Kidney Injury:
A Single Center Study. Oman medical journal. vol 37. issue 6. 2022-12-02. PMID:36458236. |
initial reports indicate a high incidence of abnormal aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in patients with covid-19 and possible association with acute kidney injury (aki). |
2022-12-02 |
2023-08-14 |
Not clear |
| Shunsuke Fukui, Kohei Ikeda, Mayu Kobayashi, Keigo Nishida, Keita Yamada, Shotaro Horie, Yasuaki Shimada, Hiroto Miki, Hiroki Goto, Koken Hayashi, Yuuichi Nakazawa, Hiroki Mizutani, Toshitaka Kamon, Yusuke Tanigaito, Shuji Kodama, Takashi Kato, Yuuki Nishiura, Daisuke Suga, Toshikazu Terashima, Yuhuko Ichikawa, Isao Moritani, Akitaka Yamamoto, Kei Takaba, Kouji Yasumoto, Hideo Wada, Katsuya Shirak. Predictive prognostic biomarkers in patients with COVID‑19 infection. Molecular medicine reports. vol 27. issue 1. 2022-12-01. PMID:36453231. |
neutrophil count, aspartate aminotransferase (ast), alanine aminotransferase, lactate dehydrogenase (ldh), c‑reactive protein (crp), sialylated carbohydrate antigen kl‑6 (kl‑6), procalcitonin (pct), presepsin (psp) and d‑dimer levels were significantly higher, and lymphocyte count and platelet count were significantly lower in the non‑severe group compared with the severe group. |
2022-12-01 |
2023-08-14 |
Not clear |
| Zhijia Fang, Yongbin Li, Jingwen Wang, Xinran Wang, Linru Huang, Lijun Sun, Qi Den. Alleviative Effect of Threonine on Cadmium-Induced Liver Injury in Mice. Biological trace element research. 2022-12-01. PMID:36454454. |
the results showed that thr significantly reduced the elevation of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in cd-exposed mice. |
2022-12-01 |
2023-08-14 |
mouse |
| Koichi Tsuboi, Hiroko Watayo, Takafumi Tsukui, Kazuto Suda, Eri Abe, Takamori Fujimoto, Takanori Ochi, Geoffrey J Lane, Hiroyuki Koga, Atsuyuki Yamatak. Native liver survivors of portoenterostomy for biliary atresia with excellent outcome: redefining "successful" portoenterostomy. Pediatric surgery international. vol 39. issue 1. 2022-12-01. PMID:36454515. |
native liver survivors (nls) after portoenterostomy (pe) for biliary atresia (ba) with normal biomarkers defined as total bilirubin (t-bil), aspartate aminotransferase (ast)/alanine aminotransferase (alt) for liver function (lf), cholinesterase (che), platelet count (pc), and absence of portal hypertension (pht) were reviewed to redefine "successful" pe. |
2022-12-01 |
2023-08-14 |
Not clear |
| Muhammed Enes Inanc, Fatma Nur Guzel, Sukru Gungor, Mine Herdogan, Feyza Nur Mart, Durmus Kahraman, Hasan Ali Cay, Ayhan At. The interaction between seminal plasma biochemical constituents and short-term semen preservation in Honamli and Hair goats. Reproduction in domestic animals = Zuchthygiene. 2022-11-30. PMID:36447389. |
diluted semen samples were cooled to +4°c; the samples were stored at this temperature; the spermatological parameters (i.e., motility, plasma membrane and acrosome integrity (pmai), viability, and high mitochondrial membrane potential) were assessed at 0, 24, 48, 72, and 144 h. a significant positive correlation was determined between the pmai, motility and viability with globulin, chlorine, alanine aminotransferase (ast), and aspartate aminotransferase (alt). |
2022-11-30 |
2023-08-14 |
Not clear |
| Sajad Badiei, Seyed Jalal Hashemi, Abdolrahim Masjedizadeh, Jalal Sayyah, Zahra Mohammadi, Sanam Hariri, Farnaz Hashemi, Zahra Rahimi, Leila Danehchin, Farhad Abolnezhadian, Reza Malihi, Yousef Paridar, Seyyed Ali Mard, Bahman Cheraghian, Hossein Poustchi, Ali Akbar Shayeste. Association between physical activity and serum liver aminotransferases in Southwestern Iran: A Cross-sectional study. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. vol 27. 2022-11-28. PMID:36438076. |
the main aim of the present study is to investigate the independent association objectively measured level of physical activity (pa) and serum concentration of liver aminotransferases (alanine aminotransferase [alt] and aspartate aminotransferase [ast]) among seemingly healthy individuals. |
2022-11-28 |
2023-08-14 |
Not clear |
| Martha Hoffman, Soon Hon Cheong, Tracy Stoko. Transient increases in glutamate dehydrogenase (GLDH) activity occur in neonatal foals. Veterinary clinical pathology. 2022-11-28. PMID:36443639. |
liver injury in horses is recognized by increased glutamate dehydrogenase (gldh), sorbitol dehydrogenase (sdh), and aspartate aminotransferase (ast) activities, whereas biliary pathology is identified by increased alkaline phosphatase and γ-glutamyl transferase (ggt) activities or bilirubin concentrations. |
2022-11-28 |
2023-08-14 |
Not clear |
| Mohamed Saleh Al-Anazi, Khaled Meghawry El-Zahar, Nourhan Abdel-Hamid Rabi. Nutritional and Therapeutic Properties of Fermented Camel Milk Fortified with Red Molecules (Basel, Switzerland). vol 27. issue 22. 2022-11-26. PMID:36431797. |
blood glucose, malondialdehyde (mda), low-density lipoprotein (ldl), cholesterol, triglyceride, aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), creatinine, and urea levels decreased dramatically in comparison to the positive control group, while high-density lipoprotein (hdl), albumin, and total protein concentrations increased significantly. |
2022-11-26 |
2023-08-14 |
rat |
| Mohammed A El-Magd, Amina M G Zedan, Nahla S Zidan, Mohamed I Sakran, Omar Bahattab, Atif Abdulwahab A Oyouni, Osama M Al-Amer, Adel I Alalawy, Amira M Elmosleman. Avocado Seeds-Mediated Alleviation of Cyclosporine A-Induced Hepatotoxicity Involves the Inhibition of Oxidative Stress and Proapoptotic Endoplasmic Reticulum Stress. Molecules (Basel, Switzerland). vol 27. issue 22. 2022-11-26. PMID:36431959. |
oral administration of 5% avs powder for 4 weeks ameliorated csa-induced hepatotoxicity, as evidenced by (1) decreased levels of liver damage parameters (alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and bilirubin), (2) resumed redox balance in the liver (reduced malondialdehyde (mda) and increased superoxide dismutase (sod), catalase (cat), and glutathione peroxidase (gpx)), (3) downregulated hepatic expression of endoplasmic reticulum (er) stress-related genes (x-box binding protein 1 ( |
2022-11-26 |
2023-08-14 |
rat |