| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan-Ling Wu, Ying-Zi Jiang, Xue-Jun Jin, Li-Hua Lian, Juan-Yu Piao, Ying Wan, Hong-Ri Jin, Jung Joon Lee, Ji-Xing Na. Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 17. issue 6. 2010-10-05. PMID:19836221. |
pretreatment with aa (50 and 100mg/kg) orally 2h before the apap administration attenuated the apap-induced acute increase in serum aspartate aminotransferase (ast), and alanine aminotransferase (alt) activites, replenished the depleted hepatic glutathione (gsh), superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gsh-px) activities, decreased malondialdehyde (mda) level and considerably reduced the histopathological alterations in a manner similar to silymarin (sily). |
2010-10-05 |
2023-08-12 |
mouse |
| G Mazzone, G Vignola, M Giammarco, A C Manetta, L Lambertin. Effects of loading methods on rabbit welfare and meat quality. Meat science. vol 85. issue 1. 2010-09-30. PMID:20374861. |
a significant neutrophilia (p<0.001), lymphocytopaenia (p<0.001) and an increase in serum aspartate aminotransferase (ast) (p<0.01), alanine aminotransferase (alt) (p<0.001) and creatine kinase (ck) activities (p<0.001) were recorded in all rabbits after transport, independent of the loading method. |
2010-09-30 |
2023-08-12 |
rabbit |
| Francesco Vetrini, Nicola Brunetti-Pierri, Donna J Palmer, Terry Bertin, Nathan C Grove, Milton J Finegold, Philip N. Vasoactive intestinal peptide increases hepatic transduction and reduces innate immune response following administration of helper-dependent Ad. Molecular therapy : the journal of the American Society of Gene Therapy. vol 18. issue 7. 2010-09-30. PMID:20461064. |
here, we show that vip pretreatment in mice is able to increase hepatocyte transduction by hdad, decrease vector uptake by the spleen, reduce elevation of proinflammatory serum cytokines interleukin (il)-6 and il-12, and reduce serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) following intravenous hdad injection. |
2010-09-30 |
2023-08-12 |
mouse |
| Hangyuan Guo, Longbin Liu, Yafei Shi, Aijing Sun, Fukang Xu, Jufang Chi, Dilai Huan. Chinese yellow wine and red wine inhibit matrix metalloproteinase-2 and improve atherosclerotic plaque in LDL receptor knockout mice. Cardiovascular therapeutics. vol 28. issue 3. 2010-09-27. PMID:20370796. |
there were no significant differences with plasma total cholesterol (tc), triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels in the four groups. |
2010-09-27 |
2023-08-12 |
mouse |
| Nigar Vardi, Hakan Parlakpinar, Asli Cetin, Ali Erdogan, I Cetin Oztur. Protective effect of beta-carotene on methotrexate-induced oxidative liver damage. Toxicologic pathology. vol 38. issue 4. 2010-09-24. PMID:20448084. |
the tissue, malondialdehyde (mda), superoxide dismutase (sod), and glutathione peroxidase (gp-x) contents and serum aspartate aminotransferase (ast) and alanine aminotranferase (alt) activities were also examined. |
2010-09-24 |
2023-08-12 |
rat |
| Riadh Abbassi, Naoufel Chamkhia, Mohsen Sakl. Chloroform-induced oxidative stress in rat liver: Implication of metallothionein. Toxicology and industrial health. vol 26. issue 8. 2010-09-24. PMID:20529963. |
malondialdehyde (mda), glutathione (gsh), reduced cytochrome c and metallothioneins (mts) levels as well as the activities of catalase (cat) and glutathione peroxidase (gpx) and the activities of the biochemical markers of hepatic injury (alanine transaminase [alt] and aspartate transaminase [ast]) were determined. |
2010-09-24 |
2023-08-12 |
rat |
| Omar Mohamed E Abdel Salam, Amany A Sleem, Nermeen Shafe. Hepatoprotective effects of the nitric oxide donor isosorbide-5-mononitrate alone and in combination with the natural hepatoprotectant, silymarin, on carbon tetrachloride-induced hepatic injury in rats. Inflammopharmacology. vol 18. issue 2. 2010-09-22. PMID:20069380. |
serum aspartate aminotransferase (ast) levels decreased by 19.8, 22.7 and 59.4%, respectively, while alkaline phosphatase (alp) decreased by 26.1 and 32.6% by the drug at 3.6 and 7.2 mg/kg, respectively. |
2010-09-22 |
2023-08-12 |
rat |
| Junming Wang, Lili Ji, Hai Liu, Zhengtao Wan. Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. Bioscience trends. vol 4. issue 2. 2010-09-22. PMID:20448345. |
serum samples were collected for determination of the biomarkers for liver injury, such as, alanine transaminase (alt) and aspartate transanimase (ast). |
2010-09-22 |
2023-08-12 |
mouse |
| Cigdem Ataman Hatipoglu, Cemal Bulut, Meltem Arzu Yetkin, Gunay Tuncer Ertem, Fatma Sebnem Erdinc, Esra Kaya Kilic, Tugba Sari, Sami Kinikli, Behic Oral, Ali Pekcan Demiro. Evaluation of clinical and laboratory predictors of fatality in patients with Crimean-Congo haemorrhagic fever in a tertiary care hospital in Turkey. Scandinavian journal of infectious diseases. vol 42. issue 6-7. 2010-09-16. PMID:20166862. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase, lactate dehydrogenase (ldh), and c-reactive protein levels were higher in fatal cases; the international normalized ratio (inr) and activated partial thromboplastin time (aptt) were longer and mean platelet counts were lower (p<0.05). |
2010-09-16 |
2023-08-12 |
Not clear |
| Mizuko Ikeda, Takako Maki, Guang Yin, Hisaya Kawate, Masahiro Adachi, Keizo Ohnaka, Ryoichi Takayanagi, Suminori Kon. Relation of coffee consumption and serum liver enzymes in Japanese men and women with reference to effect modification of alcohol use and body mass index. Scandinavian journal of clinical and laboratory investigation. vol 70. issue 3. 2010-09-16. PMID:20205615. |
previous studies have shown that coffee consumption is inversely related to serum levels of liver enzymes such as alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt), but few have addressed the relation in women and effect modifications of alcohol use and obesity. |
2010-09-16 |
2023-08-12 |
Not clear |
| Mostafa A Shalaby, Faragalla M Moghazy, Hatem A Shalaby, Soad M Nas. Effect of methanolic extract of Balanites aegyptiaca fruits on enteral and parenteral stages of Trichinella spiralis in rats. Parasitology research. vol 107. issue 1. 2010-09-15. PMID:20349194. |
bae-treated groups showed marked decreases in serum-glucose levels, triglyceride concentrations, aspartate aminotransferase (ast), creatinine phosphokinase (cpk) activities, and lipid peroxide products (malondialdehyde, mda) as well as an increase in glutathione level in both serum and muscular tissue compared to albendazole-treated- and infected-untreated groups. |
2010-09-15 |
2023-08-12 |
rat |
| Ugir Hossain Sk, Arun K Sharma, Sulekha Ghosh, Sudin Bhattachary. Synthesis and biological evaluation of novel spiro 6-methoxytetralin-1,3'-pyrrolidine based organoselenocyanates against cadmium-induced oxidative and hepatic damage in mice. European journal of medicinal chemistry. vol 45. issue 8. 2010-09-14. PMID:20457475. |
serum transaminase activities, e.g., alanine aminotransferase (alt) and aspartate aminotransferase (ast) were also significantly lowered in the compound-treated mice. |
2010-09-14 |
2023-08-12 |
mouse |
| Manan A Jhaveri, James W Anderso. Sequential changes of serum aminotransferase levels in severely obese patients after losing weight through enrollment in a behavioral weight loss program. Postgraduate medicine. vol 122. issue 4. 2010-09-14. PMID:20675984. |
the baseline levels for the an group were: alt, 25.4 u/l and aspartate aminotransferase (ast)/alt ratio, 0.87. |
2010-09-14 |
2023-08-12 |
Not clear |
| Yu-Wen Hsu, Chia-Fang Tsai, Wen-Chen Chuang, Wen-Kang Chen, Yung-Chyuan Ho, Fung-Jou L. Protective effects of silica hydride against carbon tetrachloride-induced hepatotoxicity in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 6. 2010-09-13. PMID:20350579. |
the results showed that oral administration of silica hydride significantly reduced the elevated serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), triglyceride (tg), and cholesterol and the level of malondialdehyde (mda) in the liver that were induced by ccl(4) in mice. |
2010-09-13 |
2023-08-12 |
mouse |
| b' V Nesek-Adam, Z Rasi\\xc4\\x87, D Vnuk, D Schwarz, D Rasi\\xc4\\x87, D Crvenkovi\\xc4\\x8. Ischemic preconditioning decreases laparoscopy induced oxidative stress in the liver. Collegium antropologicum. vol 34. issue 2. 2010-09-13. PMID:20698131.' |
aspartate transaminase (ast), alanine aminotransferase (alt) and lactate dehydrogenase (ldh) levels were evaluated as indicators of hepatocellular injury. |
2010-09-13 |
2023-08-12 |
Not clear |
| Hesam A Seifi, Mehrdad Mohri, Nima Farzaneh, Hadi Nemati, Shima Vahidi Nejha. Effects of anionic salts supplementation on blood pH and mineral status, energy metabolism, reproduction and production in transition dairy cows. Research in veterinary science. vol 89. issue 1. 2010-09-09. PMID:20153494. |
serum samples obtained at days -21, +3 and +21 relative to calving were analyzed for beta-hydroxybutyrate (bhba), non-esterified fatty acids (nefa), glucose, calcium (ca), inorganic phosphorus, magnesium, chloride, sodium, potassium, cholesterol, urea, creatinine, total protein, albumin, and aspartate aminotransferase (ast). |
2010-09-09 |
2023-08-12 |
Not clear |
| Brigitte Toussaint, Hendrik Emons, Heinz G Schimmel, Steffen Bossert-Reuther, Francesca Canalias, Ferruccio Ceriotti, Georges Férard, Carlo A Ferrero, Paul F H Franck, F Javier Gella, Joseph Henny, Poul J Jørgensen, Rainer Klauke, Jean-Marc Lessinger, Daniel Mazziotta, Mauro Panteghini, Shigeru Ueda, Gerhard Schuman. Traceability of values for catalytic activity concentration of enzymes: a Certified Reference Material for aspartate transaminase. Clinical chemistry and laboratory medicine. vol 48. issue 6. 2010-09-09. PMID:20441466. |
a new reference material for the liver enzyme aspartate transaminase (ast) (l-aspartate: 2-oxoglutarate-aminotransferase, ec 2.6.1.1), also called aspartate aminotransferase (asat), has been developed under the code erm-ad457/ifcc. |
2010-09-09 |
2023-08-12 |
human |
| Yu Xiong, Yuqing Yang, Jin Yang, Hongyan Chai, Ying Li, Jing Yang, Ziming Jia, Zhengrong Wan. Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ethanol-induced liver steatosis in mice. Toxicology. vol 276. issue 1. 2010-09-08. PMID:20637825. |
acute ethanol exposure resulted in the significant increase of the alanine aminotransferase (alt), aspartate aminotransferase (ast) and triglyceride (tg) levels and hepatic mitochondria dysfunction shown as the increase of mpt and the decrease of deltapsi(m). |
2010-09-08 |
2023-08-12 |
mouse |
| Oluwatosin Adekunle Adaramoy. Protective effect of kolaviron, a biflavonoid from Garcinia kola seeds, in brain of Wistar albino rats exposed to gamma-radiation. Biological & pharmaceutical bulletin. vol 33. issue 2. 2010-09-03. PMID:20118550. |
cellular alterations were monitored using changes in the levels of malondialdehyde (mda)-an index of lipid peroxidation, superoxide dismutase (sod), glutathione-s-transferase (gst), reduced glutathione (gsh), catalase (cat), alanine and aspartate aminotransferases (alt and ast), urea and creatinine. |
2010-09-03 |
2023-08-12 |
rat |
| Mohammad Ibrahim, Marina Prigol, Waseem Hassan, Cristina W Nogueira, Joao B T Roch. Protective effect of binaphthyl diselenide, a synthetic organoselenium compound, on 2-nitropropane-induced hepatotoxicity in rats. Cell biochemistry and function. vol 28. issue 4. 2010-09-03. PMID:20517888. |
against the 2-nitropropane (2-np)-induced hepatoxicity in rats, using different end points of toxicity (liver histopathology, plasma aspartate aminotransferase (ast), alanine aminotransferase (alt) and creatinine). |
2010-09-03 |
2023-08-12 |
rat |