| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kathryn Weibrecht, Matthew Dayno, Chad Darling, Steven B Bir. Liver aminotransferases are elevated with rhabdomyolysis in the absence of significant liver injury. Journal of medical toxicology : official journal of the American College of Medical Toxicology. vol 6. issue 3. 2010-11-09. PMID:20407858. |
we sought to determine the incidence of abnormal aminotransferases (defined as aspartate aminotransferase (ast) or alanine aminotransferase (alt)>40 u/l) in the setting of rhabdomyolysis and how the aminotransferases decrease relative to the creatine phosphokinase (cpk) concentration as rhabdomyolysis resolves. |
2010-11-09 |
2023-08-12 |
Not clear |
| Marco L A Sivilotti, Thomas J Green, Caillin Langmann, Mark Yarema, David Juurlink, David Johnso. Multiplying the serum aminotransferase by the acetaminophen concentration to predict toxicity following overdose. Clinical toxicology (Philadelphia, Pa.). vol 48. issue 8. 2010-11-09. PMID:20932103. |
the first available predictors of hepatic injury following acetaminophen (apap) overdose are the serum apap and aminotransferases [at, i.e., aspartate (ast) aminotransferase or alanine (alt) aminotransferase]. |
2010-11-09 |
2023-08-12 |
Not clear |
| Thomas J Green, Marco L A Sivilotti, Caillin Langmann, Mark Yarema, David Juurlink, Michael J Burns, David W Johnso. When do the aminotransferases rise after acute acetaminophen overdose? Clinical toxicology (Philadelphia, Pa.). vol 48. issue 8. 2010-11-09. PMID:20969501. |
rising aminotransferases (ats) [either aspartate aminotransferase (ast) or alanine aminotransferase (alt) are one of the first signs of hepatotoxicity following acetaminophen (apap)] overdose (od). |
2010-11-09 |
2023-08-12 |
Not clear |
| Dilshad Ahmed Khan, Imran Hashmi, Wajiha Mahjabeen, Tatheer A Naqv. Monitoring health implications of pesticide exposure in factory workers in Pakistan. Environmental monitoring and assessment. vol 168. issue 1-4. 2010-11-08. PMID:19669582. |
plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), creatinine, urea, and gamma glutamyltransferase (ggt) were measured on selectra e auto analyzer. |
2010-11-08 |
2023-08-12 |
human |
| M L Shiffman, P Pockros, J G McHutchison, E R Schiff, M Morris, G Burges. Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C. Alimentary pharmacology & therapeutics. vol 31. issue 9. 2010-11-05. PMID:20163376. |
clinical trial: the efficacy and safety of oral pf-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis c. elevated serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) reflect hepatocellular injury in patients with chronic hepatitis c virus (hcv). |
2010-11-05 |
2023-08-12 |
Not clear |
| Ravikiran Panakanti, Akshay Pratap, Ningning Yang, John S Jackson, Ram I Mahat. Triplex forming oligonucleotides against type α1(I) collagen attenuates liver fibrosis induced by bile duct ligation. Biochemical pharmacology. vol 80. issue 11. 2010-11-05. PMID:20816672. |
also, the serum alanine transaminase (alt) and aspartate transaminase (ast) concentrations were less in the tfo treated group compared to non-treated cbdl group. |
2010-11-05 |
2023-08-12 |
rat |
| Sang Kyu Lee, Mi Jeong Kang, Tae Won Jeon, Hyun Woo Ha, Jin Woo Yoo, Gyu Sub Ko, Wonku Kang, Hye Gwang Jeong, Won Seok Lyoo, Tae Cheon Jeon. Role of metabolism in 1-bromopropane-induced hepatotoxicity in mice. Journal of toxicology and environmental health. Part A. vol 73. issue 21-22. 2010-11-05. PMID:20954070. |
the decreased content of hepatic gsh produced by 1-bp was associated not only with increased activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast) but also with elevated levels of hepatic thiobarbituric acid-reactive substance (tbars) in mice where metabolic enzymes were induced by pretreatment with phenobarbital. |
2010-11-05 |
2023-08-12 |
mouse |
| Tarek M K Motawi, Nermin A H Sadik, Ayat Refaa. Cytoprotective effects of DL-alpha-lipoic acid or squalene on cyclophosphamide-induced oxidative injury: an experimental study on rat myocardium, testicles and urinary bladder. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 8-9. 2010-11-03. PMID:20573578. |
cardiac marker enzyme activities; creatine phosphokinase (cpk), lactate dehydrogenase (ldh), and aspartate transaminase (ast) showed severe declines whereas testicular markers; sorbitol dehydrogenase (sdh), gamma-glutamyl transferase (gamma-gt), acid and alkaline phosphatases (acp and alp), serum testosterone (t) level and haemoglobin (hb) absorbance were abnormal. |
2010-11-03 |
2023-08-12 |
rat |
| J F L Cobbold, M M E Crossey, P Colman, R D Goldin, P S Murphy, N Patel, J Fitzpatrick, W Vennart, H C Thomas, I J Cox, S D Taylor-Robinso. Optimal combinations of ultrasound-based and serum markers of disease severity in patients with chronic hepatitis C. Journal of viral hepatitis. vol 17. issue 8. 2010-11-01. PMID:19804501. |
a total of 67 patients with biopsy-proven chronic hepatitis c underwent all four techniques on the same visit [aspartate aminotransferase (ast) to platelet ratio index (apri); enhanced liver fibrosis (elf) panel; transient elastography (te) and ultrasound microbubble hepatic transit times (htt)]. |
2010-11-01 |
2023-08-12 |
Not clear |
| Tulay Koken, Fatih Gursoy, Ahmet Kahrama. Long-term alcohol consumption increases pro-matrix metalloproteinase-9 levels via oxidative stress. Journal of medical toxicology : official journal of the American College of Medical Toxicology. vol 6. issue 2. 2010-10-29. PMID:20405265. |
at the end of 4 weeks, blood samples were taken and plasma malondialdehyde (mda), protein carbonyls (pcs), aspartate aminotransferase (ast), tumor necrosis factor-α (tnf-α) and pmmp-9 levels were measured. |
2010-10-29 |
2023-08-12 |
human |
| S Di Domenico, G Santori, E Balbis, N Traverso, R Gentile, B Bocca, M Gelli, E Andorno, D Cottalasso, U Valent. Biochemical and morphologic effects after extended liver resection in rats: preliminary results. Transplantation proceedings. vol 42. issue 4. 2010-10-29. PMID:20534224. |
at 6 hours after resection, blood samples were obtained from the hepatic vein for measurement of reduced glutathione (gsh), oxidized glutathione (gssg), and hepatic venous oxygen saturation (shvo(2)), and for standard liver function tests including determination of concentrations of alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transpeptidase, and total bilirubin. |
2010-10-29 |
2023-08-12 |
rat |
| M Marino, R M Iemmolo, R Montalti, M Bertolotti, F Di Benedetto, N De Ruvo, N Cautero, G Guerrini, M G De Blasiis, G E Gerund. Predictive factors of lack of response to antiviral therapy among in patients with recurrent hepatitis C after liver transplantation. Transplantation proceedings. vol 42. issue 4. 2010-10-29. PMID:20534266. |
the following factors were significantly associated with a lack of svr: donor age >or=50 years (p = .046); donor body mass index (bmi) > 27 (p = .016); genotype 1 versus 2 to 3 (p = 0.010), aspartate transferase (ast) before therapy >or= 140 u/l (p = .046), alanine transferase before therapy >or= 280 u/l (p = .055), use of natural ifn versus pegylated ifn (p = .016). |
2010-10-29 |
2023-08-12 |
Not clear |
| Daniela Ennulat, Michal Magid-Slav, Sabine Rehm, Kay S Tatsuok. Diagnostic performance of traditional hepatobiliary biomarkers of drug-induced liver injury in the rat. Toxicological sciences : an official journal of the Society of Toxicology. vol 116. issue 2. 2010-10-28. PMID:20466777. |
diagnostic accuracy of alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbili), serum bile acids (sba), alkaline phosphatase (alp), gamma glutamyl transferase (ggt), total cholesterol (chol), and triglycerides (trig) was evaluated for specific types of liver histopathology by receiver operating characteristic (roc) analysis. |
2010-10-28 |
2023-08-12 |
rat |
| K J Helewski, G I Kowalczyk-Ziomek, E Czecior, E Swietochowska, T Wielkoszynski, Z P Czuba, E Szliszka, W Kro. Administration of low doses of tumor necrosis factor-alpha protects rat liver from ischaemic damage and reperfusion injury. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 61. issue 3. 2010-10-21. PMID:20610856. |
the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast), total blood antioxidant level (using the frap test), and the concentrations of tnf-alpha, myeloperoxidase (mpo) and malondialdehyde (mda) in liver homogenates after 1, 6, and 72 hours of reperfusion were measured. |
2010-10-21 |
2023-08-12 |
rat |
| Arezoo Aghakhani, Mohammad Banifazl, Ebrahim Kalantar, Ali Eslamifar, Farrokhlagha Ahmadi, Effat Razeghi, Shahnaz Atabak, Manouchehr Amini, Akbar Khadem-Sadegh, Amitis Ramezan. Occult hepatitis B virus infection in hemodialysis patients with isolated hepatitis B core antibody: a multicenter study. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. vol 14. issue 3. 2010-10-20. PMID:20609190. |
hepatitis b surface antigen (hbsag), hepatitis b surface antibody (anti-hbs), anti-hbc, hepatitis c antibody (anti-hcv), alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were tested in all subjects. |
2010-10-20 |
2023-08-12 |
human |
| b' V Calvaruso, C Camm\\xc3\\xa0, V Di Marco, S Maimone, F Bronte, M Enea, V Dardanoni, P Manousou, M Pleguezuelo, E Xirouchakis, M Attanasio, G Dusheiko, A K Burroughs, A Crax\\xc3\\xa. Fibrosis staging in chronic hepatitis C: analysis of discordance between transient elastography and liver biopsy. Journal of viral hepatitis. vol 17. issue 7. 2010-10-19. PMID:19780940.' |
by dale model, aspartate aminotransferase (ast) was found to be the unique variable significantly related (p = 0.046) with discordance between biopsy and te. |
2010-10-19 |
2023-08-12 |
Not clear |
| S H Garba, N Sambo, U Bal. The effect of the aqueous extract of Kohautia grandiflora on paracetamol-induced liver damage in albino rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 24. issue 1. 2010-10-19. PMID:19826460. |
at the end of the experimental period, blood was obtained from each rat for the determination of serum levels of aspartate transaminase [ast], alanine transaminase [alt], alkaline phosphatase [alp], albumin and bilirubin. |
2010-10-19 |
2023-08-12 |
rat |
| Justin S Ko, Mi S Gwak, Soo J Choi, Mikyung Yang, Myung J Kim, Jin Y Lee, Gaab S Kim, Choon H D Kwon, Jae W Jo. The effects of desflurane and sevoflurane on hepatic and renal functions after right hepatectomy in living donors*. Transplant international : official journal of the European Society for Organ Transplantation. vol 23. issue 7. 2010-10-18. PMID:20102552. |
aspartate aminotransferase (ast) showed significant elevations from the day of surgery to pod 3 and alanine aminotransferase (alt) was significantly elevated on pod 1 and pod 3 in the sevo group. |
2010-10-18 |
2023-08-12 |
Not clear |
| Jingyu Yang, Yan Li, Fang Wang, Chunfu W. Hepatoprotective effects of apple polyphenols on CCl4-induced acute liver damage in mice. Journal of agricultural and food chemistry. vol 58. issue 10. 2010-10-18. PMID:20415417. |
the serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), the malondialdehyde (mda), superoxide dismutase (sod), and reduced glutathione (gsh) concentrations in the hepatic homogenate, and histopathological changes in mouse liver sections were determined. |
2010-10-18 |
2023-08-12 |
mouse |
| P Charoensit, S Kawakami, Y Higuchi, F Yamashita, M Hashid. Enhanced growth inhibition of metastatic lung tumors by intravenous injection of ATRA-cationic liposome/IL-12 pDNA complexes in mice. Cancer gene therapy. vol 17. issue 7. 2010-10-12. PMID:20414324. |
moreover, reduced serum alanine transaminase (alt) and aspartate transaminase (ast) activities were observed in mice treated with atra-cationic liposome/il-12 pdna complexes. |
2010-10-12 |
2023-08-12 |
mouse |