| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M C Garavaglia, G Altomar. Etanercept therapy in patients with psoriasis and concomitant HCV infection. International journal of immunopathology and pharmacology. vol 23. issue 3. 2010-12-16. PMID:20943071. |
serum alanine aminotransferase (alt), aspartate aminotransferase (ast), and viral load were used as markers for liver damage and disease progression, respectively. |
2010-12-16 |
2023-08-12 |
Not clear |
| M Akif Yesilipek, Gulsun Karasu, Mediha Kazik, Vedat Uygun, Zeynep Oztur. Posttransplant oral iron-chelating therapy in patients with beta-thalassemia major. Pediatric hematology and oncology. vol 27. issue 5. 2010-12-15. PMID:20604682. |
no negative effect was seen in aspartate aminotransferase (ast), alanine aminotransferase (alt), hemoglobin (hb), and donor chimerism of the patients while serum ferritin levels significantly reduced (p = .018). |
2010-12-15 |
2023-08-12 |
Not clear |
| Mónica Prado, Gabriela Solano-Trejos, Bruno Lomont. Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model. Toxicon : official journal of the International Society on Toxinology. vol 56. issue 6. 2010-12-14. PMID:20638400. |
rapid increases in serum alanine (alt) and aspartate (ast) transaminases, creatinine, urea nitrogen, uric acid, sodium and chloride electrolytes, and creatine kinase (ck) were recorded, indicating damage to liver, kidneys, and skeletal muscle. |
2010-12-14 |
2023-08-12 |
mouse |
| Metehan Gümüş, Fehmi Celebi, Abdullah Böyük, Nesrin Gürsan, Fatih Akça. Dehydroepiandrosterone ameliorates hepatocellular damage in obstructive jaundice. Cell biochemistry and function. vol 28. issue 6. 2010-12-13. PMID:20803708. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma glutamyl transferase (ggt), alkaline phosphatase (alp) and bilirubin levels were lower in the treatment group than in obstructive jaundice. |
2010-12-13 |
2023-08-12 |
Not clear |
| Hyo Young Kim, Seoae Cho, Jeongmi Yu, Samsun Sung, Heebal Ki. Analysis of copy number variation in 8,842 Korean individuals reveals 39 genes associated with hepatic biomarkers AST and ALT. BMB reports. vol 43. issue 8. 2010-12-08. PMID:20797317. |
biochemical tests such as aspartate aminotransferase (ast) and alanine aminotransferase (alt) are useful for diagnosing patients with liver disease. |
2010-12-08 |
2023-08-12 |
human |
| Li Zhang, Hong-Zhong Li, Xia Gong, Fu-Ling Luo, Bin Wang, Ning Hu, Chang-Dong Wang, Zhuo Zhang, Jing-Yuan Wa. Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 17. issue 10. 2010-12-07. PMID:20171071. |
the mortality, hepatic tissue histology, plasma levels of tumor necrosis factor-alpha (tnf-alpha) and alanine aminotransferase (alt) and aspartate aminotransferase (ast), hepatic tissue tnf-alpha and caspase-3 activity were measured. |
2010-12-07 |
2023-08-12 |
mouse |
| Changchun Cai, Roop Gill, Hyun-Ae Eum, Zongxian Cao, Patricia A Loughran, Sophie Darwiche, Rebecca D Edmonds, Christoph L Menzel, Timothy R Billia. Complement factor 3 deficiency attenuates hemorrhagic shock-related hepatic injury and systemic inflammatory response syndrome. American journal of physiology. Regulatory, integrative and comparative physiology. vol 299. issue 5. 2010-12-01. PMID:20702808. |
c3(-/-) mice had significantly lower serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) and circulating dna levels, together with much lower circulating interleukin (il)-6, il-10, and high-mobility group box 1 (hmgb1) levels. |
2010-12-01 |
2023-08-12 |
mouse |
| Ebru Cetin, Murat Kanbur, Sibel Silici, Gökhan Erasla. Propetamphos-induced changes in haematological and biochemical parameters of female rats: protective role of propolis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 7. 2010-11-30. PMID:20385195. |
the levels of glucose and triglyceride, and the activities of aspartate aminotransferase (ast), alkaline phosphatase (alp), and alanine aminotransferase (alt) were increased, and total protein was decreased in serum of rats treated with propetamphos. |
2010-11-30 |
2023-08-12 |
rat |
| A O T Ashafa, T O Sunmonu, A J Afolaya. Toxicological evaluation of aqueous leaf and berry extracts of Phytolacca dioica L. in male Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 7. 2010-11-30. PMID:20450871. |
whereas, significant increase was observed in the serum levels of alkaline phosphatase (alp), gamma glutamyl transferase (ggt), alanine transaminase (alt), aspartate transaminase (ast), bilirubin, calcium, creatinine, urea and uric acid; the serum concentration of total protein, albumin and globulin were reduced in the serum following treatment with the extracts. |
2010-11-30 |
2023-08-12 |
rat |
| T O Sunmonu, A J Afolaya. Protective effect of Artemisia afra Jacq. on isoproterenol-induced myocardial injury in Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 7. 2010-11-30. PMID:20451575. |
pretreatment with the aqueous leaf extract of the plant at 100 and 200 mg/kg body weight for 30 days prevented the elevation of serum marker enzymes namely lactate dehydrogenase (ldh), aspartate transaminase (ast), alanine transaminase (alt) and alkaline phosphatase (alp) in myocardial injured rats. |
2010-11-30 |
2023-08-12 |
rat |
| Said Charef, Michel Tulliez, Liliane Esmilaire, José Courty, Dulce Papy-Garci. Toxicological evaluation of RGTA OTR4120, a heparan sulfate mimetic. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 48. issue 7. 2010-11-30. PMID:20452387. |
alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) activities were reduced female and male at dose 70 mg/kg body weight per day. |
2010-11-30 |
2023-08-12 |
mouse |
| Shemsu Umer, Kaleab Asres, Ciddi Veeresha. Hepatoprotective activities of two Ethiopian medicinal plants. Pharmaceutical biology. vol 48. issue 4. 2010-11-30. PMID:20645727. |
the levels of hepatic marker enzymes, alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) were used to assess their hepatoprotective activity against carbon tetrachloride (ccl4)-induced hepatotoxicity in swiss albino mice. |
2010-11-30 |
2023-08-12 |
mouse |
| Y X Zou, X D Zhang, Y Mao, G C Lu, M Huang, B J Yua. Acute toxicity of a single dose DATR, recombinant soluble human TRAIL mutant, in rodents and crab-eating macaques. Human & experimental toxicology. vol 29. issue 8. 2010-11-24. PMID:20053702. |
serum biochemical analysis showed an apparent increase of alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbil), blood urea nitrogen (bun) and creatinine (crea). |
2010-11-24 |
2023-08-12 |
mouse |
| B C Artun, Z Küskü-Kiraz, M Güllüoğlu, U Cevikbaş, N Koçak-Toker, M Uysa. The effect of carnosine pretreatment on oxidative stress and hepatotoxicity in binge ethanol administered rats. Human & experimental toxicology. vol 29. issue 8. 2010-11-24. PMID:20064906. |
plasma alanine (alt) and aspartate (ast) transaminase activities and liver triglyceride, malondialdehyde (mda), diene conjugate (dc), glutathione (gsh), vitamin e and vitamin c levels and superoxide dismutase (sod), glutathione peroxidase (gsh-px) and glutathione transferase (gst) activities were determined. |
2010-11-24 |
2023-08-12 |
rat |
| Faiyaz Ahmed, Asna Uroo. Hepatoprotective effects of Ficus racemosa stem bark against carbon tetrachloride-induced hepatic damage in albino rats. Pharmaceutical biology. vol 48. issue 2. 2010-11-24. PMID:20645843. |
ccl(4) administration induced a significant decrease in serum total protein, albumin, urea and a significant increase (p aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) as compared to control rats. |
2010-11-24 |
2023-08-12 |
rat |
| Qing Zhai, Xiao-Lan Bian, Bo Y. Protective activity of Jiang-Zhi-Li-Gan against carbon tetrachloride-induced hepatic injury in mice. Pharmaceutical biology. vol 48. issue 2. 2010-11-24. PMID:20645847. |
the administration of carbon tetrachloride (ccl(4)) to mice produced hepatotoxicity, showing a significant increase in the serum levels of alanine transaminase (alt) and aspartate aminotransferase (ast). |
2010-11-24 |
2023-08-12 |
mouse |
| Ana T Varela, Anabela M Simões, João S Teodoro, Filipe V Duarte, Ana P Gomes, Carlos M Palmeira, Anabela P Rol. Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition. Mitochondrion. vol 10. issue 5. 2010-11-23. PMID:20433952. |
acute treatment with ind decreased serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) levels, comparatively to i/r livers. |
2010-11-23 |
2023-08-12 |
rat |
| T J S Cross, V Calvaruso, M R Foxton, P Manousou, A Quaglia, F Grillo, A P Dhillon, J Nolan, T P Chang, J O'Grady, M A Heneghan, J P O'Beirne, A K Burroughs, P M Harriso. A simple, noninvasive test for the diagnosis of liver fibrosis in patients with hepatitis C recurrence after liver transplantation. Journal of viral hepatitis. vol 17. issue 9. 2010-11-16. PMID:19922441. |
the london transplant centres' (ltc) score was derived combining aspartate aminotransferase (ast iu/l), time from liver transplant (tflt months), international normalized ratio and platelets. |
2010-11-16 |
2023-08-12 |
Not clear |
| Saad Zaky, Ahlam Mohamed Farghaly, Hebat-Allah Rashed, Hywida Hassan, Ehab Faouzy, Nahed Makhlouf, Mahmoud Rezk Abdelwahed Hussei. Clinicopathologic features and genotyping of patients with chronic HBV infection in the Upper Egypt. Cellular immunology. vol 265. issue 2. 2010-11-16. PMID:20719306. |
positive correlation was found among serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), histological activity index and grade of hepatitis. |
2010-11-16 |
2023-08-12 |
Not clear |
| Yukiko Washino, Eriko Koga, Yuko Kitamura, Chiaki Kamikawa, Keiko Kobayashi, Tomoka Nakagawa, Chihiro Nakazaki, Ikuyo Ichi, Shosuke Koj. Effect of celecoxib, a selective cyclooxygenase-2 inhibitor on carbon tetrachloride intoxication in rats. Biological & pharmaceutical bulletin. vol 33. issue 4. 2010-11-12. PMID:20410610. |
twelve hours after administration of ccl(4), plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, indicators of liver necrosis, were significantly higher than those in the control group showing that active liver necrosis took place. |
2010-11-12 |
2023-08-12 |
rat |