| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ren-Bo Ding, Ke Tian, Yi-Wei Cao, Jiao-Lin Bao, Meng Wang, Chengwei He, Yuanjia Hu, Huanxing Su, Jian-Bo Wa. Protective effect of panax notoginseng saponins on acute ethanol-induced liver injury is associated with ameliorating hepatic lipid accumulation and reducing ethanol-mediated oxidative stress. Journal of agricultural and food chemistry. vol 63. issue 9. 2015-12-03. PMID:25665731. |
acute alcohol gavage dramatically significantly increased serum activities of alanine aminotransferase (alt) (23.4 ± 5.0 iu/l vs 11.7 ± 4.1 iu/l) and aspartate aminotransferase (ast) (52.6 ± 14.9 iu/l vs 31.1 ± 12.9 iu/l), and hepatic triglyceride level (4.04 ± 0.64 mg/g vs 1.92 ± 0.34 mg/g), these elevations were significantly diminished by pretreatment with pns at dose of 100 mg/kg or 300 mg/kg. |
2015-12-03 |
2023-08-13 |
mouse |
| InSil Park, JinAh Ryuk, HyeWon Lee, Hiroe Go, ByoungSeob K. In vitro and in vivo effects of ethanol extract combined with Curcumae Radix and Glycyrrhizae Radix et Rhizoma on menopausal metabolic disturbances. International journal of clinical and experimental medicine. vol 8. issue 9. 2015-12-02. PMID:26628991. |
furthermore, cr+gr (200 or 450 mg/kg/day) ameliorated the serum levels of the liver enzymes aspartate aminotransferase (ast) and alanine transaminase (alt) compared to the ovx-hfhc group. |
2015-12-02 |
2023-08-13 |
rat |
| Shuanghai Dong, Yun Cao, Haoqing Li, Jiwei Tian, Chengqing Yi, Weilin San. Impact of ischemic preconditioning on ischemia-reperfusion injury of the rat sciatic nerve. International journal of clinical and experimental medicine. vol 8. issue 9. 2015-12-02. PMID:26629140. |
serum concentrations of aspartate aminotransferase (ast), lactate dehydrogenase (ldh), malondialdehyde (mda), and superoxide dismutase (sod) were assessed following reperfusion. |
2015-12-02 |
2023-08-13 |
rat |
| Gang Guo, Xian-Zheng Wu, Li-Jie Su, Chang-Qing Yan. Clinical features of ischemic hepatitis caused by shock with four different types: a retrospective study of 328 cases. International journal of clinical and experimental medicine. vol 8. issue 9. 2015-12-02. PMID:26629201. |
the parameters of liver function test, including alanine aminotransferanse (alt), aspartate aminotransferanse (ast), lactate dehydrogenase (ldh), total bilirubin (tb), alkaline phosphatase (alp) and γ-glutamyltransferase (γ-gt), were recorded and analyzed. |
2015-12-02 |
2023-08-13 |
Not clear |
| Alexey P Sarapultsev, Oleg N Chupakhin, Petr A Sarapultsev, Maxim A Rantsev, Svetlana U Medvedeva, Larisa P Sidorov. Effect of a new class of compounds of the group of substituted 5R1, 6H2-1,3,4-thiadiazine-2-amines on the inflammatory and cytokine response in experimental myocardial infarction. Current vascular pharmacology. vol 13. issue 1. 2015-11-30. PMID:23628009. |
serum activity of creatine phosphokinase (cpk), aspartate aminotransferase (ast), isoenzymes 1 and 2 and lactate dehydroge nase (ldh1-2) were investigated at days 1(st)and 7(th). |
2015-11-30 |
2023-08-12 |
rat |
| Mohammad Najafi, Abazar Roustazadeh, Ali Asghar Moshtaghie, Mohsen An. Liver aspartate transaminase isoenzymes as biomarkers of chronic exposure to chromium(VI). Arhiv za higijenu rada i toksikologiju. vol 64. issue 4. 2015-11-30. PMID:24384761. |
the aim of this study was to compare liver isoenzyme and total serum activities of aspartate aminotransferase (ast) as cytotoxic biomarkers of acute and chronic cytotoxicity of cr(vi). |
2015-11-30 |
2023-08-12 |
Not clear |
| Abdelkareem A Ahmed, Jaafar S Fedail, Hassan H Musa, Asghar Ali Kamboh, Amal Z Sifaldin, Taha H Mus. Gum Arabic extracts protect against hepatic oxidative stress in alloxan induced diabetes in rats. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 22. issue 4. 2015-11-30. PMID:26321624. |
in addition, ga was significantly (p<0.05) reduced the activities of key liver enzymes, including alanine transaminase (alt) and aspartate transaminase (ast). |
2015-11-30 |
2023-08-13 |
rat |
| Sharman M Hoppes, Janice D Boyd, Donald J Brightsmit. Impact of Delayed Analysis in Avian Blood Biochemical Values Measured With the Abaxis VetScan VS2. Journal of avian medicine and surgery. vol 29. issue 3. 2015-11-30. PMID:26378666. |
major increases by 24 hours after collection were observed in phosphorus (+67%) and potassium (+103%) concentrations, whereas aspartate aminotransferase (ast), uric acid, glucose, and sodium concentrations also showed statistically significant changes. |
2015-11-30 |
2023-08-13 |
Not clear |
| Lu Cai, Kai Hu, Ling Lin, Qing Ai, Pu Ge, Yiqing Liu, Jie Dai, Bin Ye, Li Zhan. AMPK dependent protective effects of metformin on tumor necrosis factor-induced apoptotic liver injury. Biochemical and biophysical research communications. vol 465. issue 3. 2015-11-27. PMID:26265045. |
the results indicated that treatment with metformin significantly suppressed the elevation of plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast), the activation of caspase cascade and the induction of cleaved caspase-3. |
2015-11-27 |
2023-08-13 |
mouse |
| Andréa G B Leite, Maria Irma S Duarte, Maria Cássia Mendes-Corre. Fibrosis Progression in Paired Liver Biopsies from HIV/HCV-Coinfected Patients without Prior Treatment of Hepatitis C. Journal of the International Association of Providers of AIDS Care. vol 14. issue 5. 2015-11-24. PMID:26056147. |
liver fibrosis progression was associated with alanine aminotransferase (alt; p < .001) and aspartate aminotransferase (ast; p < .0340) levels over 3 times the upper limit of normal present at first biopsy. |
2015-11-24 |
2023-08-13 |
Not clear |
| Roza Dianita, Ibrahim Jantan, Athirah Z Amran, Juriyati Jali. Protective effects of Labisia pumila var. alata on biochemical and histopathological alterations of cardiac muscle cells in isoproterenol-induced myocardial infarction rats. Molecules (Basel, Switzerland). vol 20. issue 3. 2015-11-23. PMID:25786162. |
the extracts showed significant protective effects as pretreated rats showed a significant dose-dependent decrease (p < 0.05) in cardiac enzyme activities, i.e., cardiac troponin i (ctni), creatine kinase mb isoenzyme (ck-mb), lactate dehydrogenase (ldh), alanine transaminase (alt) and aspartate transaminase (ast), when compared with iso-control rats. |
2015-11-23 |
2023-08-13 |
rat |
| Ming Li, Lin Zhu, Ao Xie, Jieli Yua. Oral administration of Saccharomyces boulardii ameliorates carbon tetrachloride-induced liver fibrosis in rats via reducing intestinal permeability and modulating gut microbial composition. Inflammation. vol 38. issue 1. 2015-11-20. PMID:25227279. |
results showed that the liver expression levels of collagen, type i, alpha 1 (col1a1), alpha smooth muscle actin (αsma), transforming growth factor beta (tgf-β) and the serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and malondialdehyde (mda) increased significantly in cirrhotic rats compared with control and decreased by s. boulardii administration. |
2015-11-20 |
2023-08-13 |
rat |
| Ali Jebali, Seyed Ali Yasini Ardakani, Hossein Shahdadi, Mohammad Hossein Balal Zadeh, Seyedhossein Hekmatimoghadda. Modification of nanocellulose by poly-lysine can inhibit the effect of fumonisin B1 on mouse liver cells. Colloids and surfaces. B, Biointerfaces. vol 126. 2015-11-20. PMID:25601749. |
then, the level of aniline aminotransferase (alt) and aspartate aminotransferase (ast) was evaluated. |
2015-11-20 |
2023-08-13 |
mouse |
| Muthuraman Pandurangan, Doo Hwan Ki. ZnO nanoparticles augment ALT, AST, ALP and LDH expressions in C2C12 cells. Saudi journal of biological sciences. vol 22. issue 6. 2015-11-20. PMID:26586993. |
the present study aimed to investigate the effect of zno nanoparticles on alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) and lactate dehydrogenase (ldh) enzyme expressions in c2c12 cells. |
2015-11-20 |
2023-08-13 |
Not clear |
| Jae-Jung Kim, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung-Yil Lee, Hong-Ryang Kil, Gi Beom Kim, Myung Ki Han, Min Seob Song, Hyoung Doo Lee, Jung Hye Byeon, Saejung Sohn, Young Mi Hong, Gi Young Jang, Jong-Keuk Le. Common variants in the CRP promoter are associated with a high C-reactive protein level in Kawasaki disease. Pediatric cardiology. vol 36. issue 2. 2015-11-17. PMID:25266886. |
we here performed a genome-wide association study (gwas) of 178 kd patients to identify the genetic loci that influence 10 important kd laboratory markers: wbc count, neutrophil count, platelet count, crp, esr, hemoglobin, aspartate aminotransferase (ast), alanine aminotransferase (alt), albumin, and total protein. |
2015-11-17 |
2023-08-13 |
Not clear |
| Atallah F Ahmed, Jawaher H Al-Qahtani, Hanan M Al-Yousef, Mansour S Al-Said, AbdelKader E Ashour, Mohammed Al-Sohaibani, Syed Rafatulla. Proanthocyanidin-rich date seed extract protects against chemically induced hepatorenal toxicity. Journal of medicinal food. vol 18. issue 3. 2015-11-16. PMID:25569813. |
relative to the control ccl4-intoxicated group, pretreatment with dtx significantly (p<.001) suppressed the elevated serum levels of alanine aminotransferase and aspartate aminotransferase (alt and ast), alkaline phosphatase (alp), γ-glutamyl transferase (ggt), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), bilirubin, creatinine, and calcium, whereas it significantly (p<.001) increased the diminished serum levels of high-density lipoprotein cholesterol (hdl-c) and total protein (tp). |
2015-11-16 |
2023-08-13 |
rat |
| Qian Xu, Trefor Higgins, George S Cembrowsk. Limiting the testing of AST: a diagnostically nonspecific enzyme. American journal of clinical pathology. vol 144. issue 3. 2015-11-13. PMID:26276772. |
annually, millions of pairs of alanine aminotransferase (alt) and aspartate aminotransferase (ast) tests are ordered. |
2015-11-13 |
2023-08-13 |
Not clear |
| S A Saïdi, S Abdelkafi, S Jbahi, J van Pelt, A El-Fek. Temporal changes in hepatic antioxidant enzyme activities after ischemia and reperfusion in a rat liver ischemia model: effect of dietary fish oil. Human & experimental toxicology. vol 34. issue 3. 2015-11-10. PMID:24939873. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were measured in the plasma. |
2015-11-10 |
2023-08-13 |
rat |
| Zhong-Qian Lu, Jian-Xia Lu, Yi-Jun Den. Glucocorticoids offer protection against myocardial injury in a murine model of sepsis. International journal of clinical and experimental medicine. vol 8. issue 8. 2015-11-09. PMID:26550131. |
clp rats also had a rise in serum tumor necrosis factor-alpha (tnf-α), interleukin-6 (il-6), c-reactive protein (crp), cardiac troponin i (ctni), creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast), and nf-κb p65 in myocardial tissues. |
2015-11-09 |
2023-08-13 |
rat |
| Lufeng Hu, Fan Wang, Jinzhong Xu, Xiaofang Wang, Hong Lin, Yi Zhang, Yang Yu, Youpei Wang, Lingxia Pang, Xi Zhang, Qi Liu, Guoshi Qiu, Yongsheng Jiang, Longteng Xie, Yanlong Li. Prediction of liver injury using the BP-ANN model with metabolic parameters in overweight and obese Chinese subjects. International journal of clinical and experimental medicine. vol 8. issue 8. 2015-11-09. PMID:26550266. |
alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyl transferase (ggt) are standard clinical markers for liver injury. |
2015-11-09 |
2023-08-13 |
human |