| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Qiong Deng, Hong Zhao, An-Lin Ma, Ji-Yuan Zhou, Shi-Bin Xie, Xu-Qing Zhang, Da-Zhi Zhang, Qing Xie, Guo Zhang, Jia Shang, Jun Cheng, Wei-Feng Zhao, Zhi-Qiang Zou, Ming-Xiang Zhang, Gui-Qiang Wan. Selected Cytokines Serve as Potential Biomarkers for Predicting Liver Inflammation and Fibrosis in Chronic Hepatitis B Patients With Normal to Mildly Elevated Aminotransferases. Medicine. vol 94. issue 45. 2016-02-25. PMID:26559292. |
compared to existing scores, fib-index was significantly superior to aspartate aminotransferase (ast) to platelet ratio index (apri) and fib-4 score for significant fibrosis. |
2016-02-25 |
2023-08-13 |
Not clear |
| Xuan Shi, Huihui Ma, Changqing Tong, Min Qu, Qiao Jin, Wei L. Hepatoprotective effect of a polysaccharide from Crassostrea gigas on acute and chronic models of liver injury. International journal of biological macromolecules. vol 78. 2016-02-24. PMID:25869310. |
treatment with cgps-1 decreased serum aspartate aminotransferase (ast), serum alanine aminotransferase (alt), and malondialdehyde (mda) levels; increased superoxide dismutase (sod) activity; and improved hepatic injury in both the acute and chronic models of liver injury in mice. |
2016-02-24 |
2023-08-13 |
mouse |
| Shenquan Liao, Dayou Shi, Connie L Clemons-Chevis, Shining Guo, Rongsheng Su, Panjia Qiang, Zhaoxin Tan. Protective role of selenium on aflatoxin b1-induced hepatic dysfunction and apoptosis of liver in ducklings. Biological trace element research. vol 162. issue 1-3. 2016-02-23. PMID:25274191. |
blood samples were obtained on the 14th, 21st, and 28th days of post-administration, and the serum alanine aminotransferase (alt) and aspartate transaminase (ast) were evaluated. |
2016-02-23 |
2023-08-13 |
Not clear |
| Ping Chen, Yang Chen, Yarong Wang, Shining Cai, Liang Deng, Jia Liu, Hao Zhan. Comparative Evaluation of Hepatoprotective Activities of Geniposide, Crocins and Crocetin by CCl4-Induced liver Injury in Mice. Biomolecules & therapeutics. vol 24. issue 2. 2016-02-23. PMID:26902084. |
hepatoprotective properties were evaluated by biochemical parameters: administration of geniposide, crocins, crocin-1and crocetin significantlylowered serum alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) levels in ccl4-treated mice. |
2016-02-23 |
2023-08-13 |
mouse |
| Amal Derbali, Kais Mnafgui, Marwa Affes, Fatma Derbali, Raouf Hajji, Neji Gharsallah, Noureddine Allouche, Abdelfattah El Fek. Cardioprotective effect of linseed oil against isoproterenol-induced myocardial infarction in Wistar rats: a biochemical and electrocardiographic study. Journal of physiology and biochemistry. vol 71. issue 2. 2016-02-17. PMID:25910460. |
isoproterenol injection showed changes in ecg pattern, including st-segment elevation (diagnostic of myocardial infarction), increase in the serum levels of troponin t and cardiac injury markers (creatine kinase-mb (ck-mb), lactate dehydrogenase (ldh), alkaline phosphatase (alp), aspartate transaminase (ast), and alanine transaminase (alt)). |
2016-02-17 |
2023-08-13 |
rat |
| Chen Chen, Da-Chao Wen, Shu-di Gao, Xiao-Yu Hu, Cheng Y. The Protective Effects of Buzui on Acute Alcoholism in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-02-17. PMID:26884793. |
blood alcohol concentrations, alanine aminotransferase (alt) levels, aspartate aminotransferase (ast) levels, and alkaline phosphatase (alp) levels were recorded. |
2016-02-17 |
2023-08-13 |
mouse |
| Ahmet Fikret Yucel, Ahmet Pergel, Ibrahim Aydin, Hasan Alacam, Ilhan Karabicak, Tugrul Kesicioglu, Levent Tumkaya, Yildiray Kalkan, Ender Ozer, Zakir Arslan, Ibrahim Sehitoglu, Dursun Ali Sahi. Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885068. |
aspartate aminotransferase (ast), alanine aminotransferase (alt), tnf-α, malondialdehyde (mda), and glutathione peroxidase (gsh-px) levels were measured in the serum. |
2016-02-17 |
2023-08-13 |
rat |
| Shuqiang Jin, Haili Cao, Kaibing Wang, Ying Li, Bin Ba. Preventative effects of prostaglandin E1 in combination with iodized olive oil on liver fibrosis after transcatheter arterial chemoembolization in a rabbit model of CCl4-induced liver fibrosis. Canadian journal of physiology and pharmacology. vol 93. issue 6. 2016-02-16. PMID:25928762. |
body mass and serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total protein (tp), albumin (alb), albumin:globulin ratio (a:g), total bilirubin (tbil), and direct bilirubin (dbil) were measured. |
2016-02-16 |
2023-08-13 |
rabbit |
| Yafan Song, Chunyan Zhang, Congxia Wang, Ling Zhao, Zheng Wang, Zhijun Dai, Shuai Lin, Huafeng Kang, Xiaobin M. Ferulic Acid against Cyclophosphamide-Induced Heart Toxicity in Mice by Inhibiting NF-κB Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2016-02-16. PMID:26881001. |
the results indicated that fa significantly decreased the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), creatine kinase (ck), lactate dehydrogenase (ldh), interleukin-6 (il-6), il-1β, and tumor necrosis factor-α (tnf-α) in ctx-injected mice. |
2016-02-16 |
2023-08-13 |
mouse |
| Amalia E Yanni, Vissarion Efthymiou, Pavlos Lelovas, George Agrogiannis, Nikolaos Kostomitsopoulos, Vaios T Karathano. Effects of dietary Corinthian currants (Vitis vinifera L., var. Apyrena) on atherosclerosis and plasma phenolic compounds during prolonged hypercholesterolemia in New Zealand White rabbits. Food & function. vol 6. issue 3. 2016-02-11. PMID:25662939. |
the high-cholesterol diet resulted in hypercholesterolemia and oxidative stress, increased aspartate aminotransferase (ast) activity and induced aortic and hepatic lesion formation. |
2016-02-11 |
2023-08-13 |
rabbit |
| Yi-Wei Cao, Yun Jiang, Da-Yong Zhang, Xiao-Jing Zhang, Yuan-Jia Hu, Peng Li, Huanxing Su, Jian-Bo Wa. The hepatoprotective effect of aqueous extracts of Penthorum chinense Pursh against acute alcohol-induced liver injury is associated with ameliorating hepatic steatosis and reducing oxidative stress. Food & function. vol 6. issue 5. 2016-02-05. PMID:25820653. |
pretreatment with pcp significantly decreased the elevations of alanine aminotransferase (alt), aspartate aminotransferase (ast) and hepatic triglyceride after the last ethanol administration. |
2016-02-05 |
2023-08-13 |
mouse |
| Jianjun Guo, Yonghong Meng, Yan Zhao, Yuanyuan Hu, Daoyuan Ren, Xingbin Yan. Myricetin derived from Hovenia dulcis Thunb. ameliorates vascular endothelial dysfunction and liver injury in high choline-fed mice. Food & function. vol 6. issue 5. 2016-02-05. PMID:25881982. |
furthermore, continuous administration of myr at 400 and 800 mg per kg bw in choline-fed mice could significantly decrease the high choline diet-induced elevation of serum total cholesterol (tc), total triglyceride (tg), low density lipoprotein-cholesterol (ldl-c), endothelin 1 (et-1) and thromboxane a2 (txa2) levels as well as alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, while the choline-induced decline of serum high density lipoprotein-cholesterol (hdl-c), endothelin nitric oxide synthase (enos), nitric oxide (no) and prostaglandin i2 (pgi2) levels could be markedly elevated in mice (p < 0.05, p < 0.01). |
2016-02-05 |
2023-08-13 |
mouse |
| Wan-Chun Chiu, Ya-Li Huang, Ya-Ling Chen, Hsiang-Chi Peng, Wei-Hsiang Liao, Hsiao-Li Chuang, Jiun-Rong Chen, Suh-Ching Yan. Synbiotics reduce ethanol-induced hepatic steatosis and inflammation by improving intestinal permeability and microbiota in rats. Food & function. vol 6. issue 5. 2016-02-05. PMID:25910227. |
male wistar rats were divided into four groups according to plasma aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities and subjected to either a normal liquid diet (c), a normal liquid diet with synbiotic supplementation (c + s), an ethanol liquid diet (e), or an ethanol liquid diet with synbiotic supplementation (e + s) for 12 weeks. |
2016-02-05 |
2023-08-13 |
rat |
| Tomonori Morita, Masashi Ishikawa, Atsuhiro Sakamot. Identical MicroRNAs Regulate Liver Protection during Anaesthetic and Ischemic Preconditioning in Rats: An animal study. PloS one. vol 10. issue 5. 2016-02-04. PMID:25974021. |
blood samples were collected to measure the levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
2016-02-04 |
2023-08-13 |
rat |
| Xiang-Pan Chen, Jie-Ren Yang, Xian-Wei Li, Wei Hao, Yan Liu, Jun-Xiu Zhan. [Effects of sequoyitol on expression of NADPH oxidase subunits p22 phox and p47 phox in rats with type 2 diabetic liver disease]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 4. 2016-02-02. PMID:23833934. |
after sequoyitol (50, 25 and 12.5 mg x kg(-1)) was administrated for 6 weeks, the contents of blood glucose (bg), alanine aminotransferase (alt), aspartate aminotransferase (ast), total antioxidant capacity (t-aoc), hydrogen peroxide (h2o2), no and insulin (ins) were measured, liver p22 phox and p47 phox mrna content was determined with real-time pcr and the expression of p22 phox and p47 phox protein was examined by western blotting. |
2016-02-02 |
2023-08-12 |
rat |
| Shuang Xu, Jin-Feng Hu, Shi-Feng Chu, Ning Han, Jing-Wei Li, Yue-Ting Li, Nai-Hong Che. [Oil of Piper longum unsaponifiable matter prevents cholesterol gallstone formation]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 7. 2016-02-02. PMID:24133988. |
the results showed that serum tc, tg (triglycerides) and ast (aspartate transaminase) contents, gallbladder cholesterol crystallization and csi increased significantly (p < 0.05). |
2016-02-02 |
2023-08-12 |
mouse |
| Balan Rajan, Shanmugam Sathish, Subramanian Balakumar, Thiruvengadam Devak. Synthesis and dose interval dependent hepatotoxicity evaluation of intravenously administered polyethylene glycol-8000 coated ultra-small superparamagnetic iron oxide nanoparticle on Wistar rats. Environmental toxicology and pharmacology. vol 39. issue 2. 2016-01-25. PMID:25721486. |
the results of our study showed a significant increase in the aspartate transaminase (ast) enzyme activity at a dose of 10mg/kg b.w. |
2016-01-25 |
2023-08-13 |
rat |
| Yichao Yan, Guangying Li, Xiaofeng Tian, Yingjiang Ye, Zhidong Gao, Jihong Yao, Feng Zhang, Shan Wan. Ischemic preconditioning increases GSK-3β/β-catenin levels and ameliorates liver ischemia/reperfusion injury in rats. International journal of molecular medicine. vol 35. issue 6. 2016-01-25. PMID:25813855. |
following reperfusion, liver pathology, as well as alanine aminotransferase (alt), aspartate aminotransferase (ast), maleic dialdehyde (mda) and superoxide dismutase (sod) levels were assessed. |
2016-01-25 |
2023-08-13 |
rat |
| Qi Guo, Zhiyang Shen, Hongxia Yu, Gaofeng Lu, Yong Yu, Xia Liu, Pengyuan Zhen. Carnosic acid protects against acetaminophen-induced hepatotoxicity by potentiating Nrf2-mediated antioxidant capacity in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 1. 2016-01-25. PMID:26807019. |
the levels of both alanine aminotransferase (alt) and aspartate transaminase (ast) in serum were reduced by ca treatment. |
2016-01-25 |
2023-08-13 |
mouse |
| Philip B Busbee, Mitzi Nagarkatti, Prakash S Nagarkatt. Natural indoles, indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), attenuate staphylococcal enterotoxin B-mediated liver injury by downregulating miR-31 expression and promoting caspase-2-mediated apoptosis. PloS one. vol 10. issue 2. 2016-01-22. PMID:25706292. |
injection of seb into d-galactosamine-sensitized female c57bl/6 mice resulted in liver injury as indicated by an increase in enzyme aspartate transaminase (ast) levels, induction of inflammatory cytokines, and massive infiltration of immune cells into the liver. |
2016-01-22 |
2023-08-13 |
mouse |