| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pradeep Kumar, Tekla Smith, Khalidur Rahman, Natalie E Thorn, Frank A Anani. Adiponectin agonist ADP355 attenuates CCl4-induced liver fibrosis in mice. PloS one. vol 9. issue 10. 2015-12-28. PMID:25310107. |
biochemical studies suggested adp355 treatment attenuates liver fibrosis, determined by reduction of serum aspartate aminotransferase (ast), alanine aminotransferase alt) and hydroxyproline. |
2015-12-28 |
2023-08-13 |
mouse |
| Kleber Juvenal Silva Farias, Paula Renata Lima Machado, José Augusto Pereira Carneiro Muniz, Aline Amaral Imbeloni, Benedito Antônio Lopes da Fonsec. Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeys. Viral immunology. vol 28. issue 3. 2015-12-22. PMID:25664975. |
a significant decrease in systemic levels of the liver enzyme aspartate aminotransferase (ast) was also observed in the animals treated with clq after infection compared with the controls. |
2015-12-22 |
2023-08-13 |
monkey |
| Kate Hallsworth, Christian Thoma, Kieren G Hollingsworth, Sophie Cassidy, Quentin M Anstee, Christopher P Day, Michael I Trenel. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. Clinical science (London, England : 1979). vol 129. issue 12. 2015-12-22. PMID:26265792. |
relative to control, hiit decreased liver fat (11±5% to 8±2% compared with 10±4% to 10±4% p=0.019), whole-body fat mass (35±7 kg to 33±8 kg compared with 31±9 kg to 32±9 kg, p=0.013), alanine (52±29 units/l to 42±20 units/l compared with 47±22 units/l to 51±24 units/l, p=0.016) and aspartate aminotransferase (ast; 36±18 units/l to 33±15 units/l compared with 31±8 units/l to 35±8 units/l, p=0.017) and increased early diastolic filling rate (244±84 ml/s to 302±107 ml/s compared with 255±82 ml/s to 251±82 ml/s, p=0.018). |
2015-12-22 |
2023-08-13 |
Not clear |
| Charlene Menezes, Ignacio Ruiz-Jarabo, Juan Antonio Martos-Sitcha, Jossiele Leitemperger, Bernardo Baldisserotto, Juan Miguel Mancera, Denis Broock Rosemberg, Vania Lucia Lor. Diet with diphenyl diselenide mitigates quinclorac toxicity in silver catfish (Rhamdia quelen). PloS one. vol 9. issue 12. 2015-12-21. PMID:25469630. |
moreover, the activities of fructose biphosphatase (fbpase), glucose-6-phosphate dehydrogenase (g6pase), glycogen phosphorilase (gpase) and aspartate aminotransferase (ast) were significantly increased in liver. |
2015-12-21 |
2023-08-13 |
cat |
| Tomoko Watanabe, Manami Miyake, Toshinobu Shimizu, Miho Kamezawa, Naoya Masutomi, Takesada Shimura, Rikiya Ohash. Utility of bilirubins and bile acids as endogenous biomarkers for the inhibition of hepatic transporters. Drug metabolism and disposition: the biological fate of chemicals. vol 43. issue 4. 2015-12-17. PMID:25581390. |
in rats administered 20 and 80 mg/kg rifampicin, the plasma levels of bilirubin glucuronides were elevated, gradually decreased, and almost returned to the baseline level at 24 hours after administration without an elevation of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2015-12-17 |
2023-08-13 |
rat |
| Katsuhito Nagai, Ayano Oda, Hiroki Konish. Theanine prevents doxorubicin-induced acute hepatotoxicity by reducing intrinsic apoptotic response. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 78. 2015-12-17. PMID:25680506. |
activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in serum, biomarkers of hepatic impairment, were markedly increased after the administration of 20 mg/kg dox, whereas the degree of these elevations was significantly attenuated by 10 mg/kg theanine, which was consistent with histological hepatic images assessed by microscopic examination. |
2015-12-17 |
2023-08-13 |
mouse |
| Zi-jing Zhao, Zheng Gong, Shao-ze Shi, Jin-lan Yang, Na-na Ma, Qi Wan. [Toxicokinetics of bakuchiol, hepatic and renal toxicity in rats after single oral administration of Psoraleae Fructus and combination with Glycyrrhizae Radix et Rhizoma]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 40. issue 11. 2015-12-17. PMID:26552185. |
plasma alanine transaminase (alt), aspartate aminotransferase (ast), blood urea nitrogen (bun), plasma creatinine (cr), n-acetyl-β-d-glucosaminidase (nag) and kidney injury molecule 1 (kim-1) were measured after administration for 24 h. the main toxicokinetics parameters of bakuchiol in rats exert significantly gender difference. |
2015-12-17 |
2023-08-13 |
rat |
| Muthuswamy Umamaheswari, Kuppusamy Asokkumar, Nandagopi Umamageswari, Thirumalaisamy Sivashanmugam, Varadharajan Subhadradev. Protective effect of the leaves of Vitex negundo against ethanol-induced cerebral oxidative stress in rats. Tanzania journal of health research. vol 14. issue 1. 2015-12-17. PMID:26591743. |
administration of ethanol resulted in a significant elevation in serum biochemical parameters like aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), uric acid, triglycerides and lipoprotein levels. |
2015-12-17 |
2023-08-13 |
rat |
| Isabele C Angelo, Vinícius M Tunholi-Alves, Victor M Tunholi, Wendell M S Perinotto, Patrícia S Gôlo, Mariana G Camargo, Simone Quinelato, Jairo Pinheiro, Vânia R E P Bittencour. Physiological changes in Rhipicephalus microplus (Acari: Ixodidae) experimentally infected with entomopathogenic fungi. Parasitology research. vol 114. issue 1. 2015-12-15. PMID:25346195. |
the parameters evaluated were glucose concentration, enzymatic activities of lactate dehydrogenase (ldh), alanine aminostransferase (alt) and aspartate aminostransferase (ast), amounts of uric acid and urea in the hemolymph, and amount of glycogen in the fat body. |
2015-12-15 |
2023-08-13 |
Not clear |
| Chen-Chung Liao, Ya-Lin Lin, Chia-Feng Ku. Effect of high-fat diet on hepatic proteomics of hamsters. Journal of agricultural and food chemistry. vol 63. issue 6. 2015-12-15. PMID:25634685. |
the animals maintained on the high-fat diet had significantly (p < 0.05) higher serum triglyceride, cholesterol, aspartate aminotransferase (ast), alanine aminotransferase (alt), and uric acid. |
2015-12-15 |
2023-08-13 |
human |
| Gang Ning, Lanhui She, Lirong Lu, Ying Liu, Yingfu Zeng, Ying Yan, Chaoshuang Li. Analysis of monocytic and granulocytic myeloid-derived suppressor cells subsets in patients with hepatitis C virus infection and their clinical significance. BioMed research international. vol 2015. 2015-12-15. PMID:25815313. |
the frequency of m-mdscs, however, had no correlation with hcv rna loads, aspartate aminotransferase (ast), alanine aminotransferase (alt), and the level of liver inflammation degree. |
2015-12-15 |
2023-08-13 |
Not clear |
| Anikó Pósa, Renáta Szabó, Krisztina Kupai, Anett Csonka, Zita Szalai, Médea Veszelka, Szilvia Török, Lejla Daruka, Csaba Varg. Exercise training and calorie restriction influence the metabolic parameters in ovariectomized female rats. Oxidative medicine and cellular longevity. vol 2015. 2015-12-15. PMID:25874022. |
the metabolic syndrome was assessed by measuring the body weight gain, the glucose sensitivity, and the levels of insulin, triglyceride, leptin, and aspartate aminotransferase transaminase (ast) and alanine aminotransferase (alt). |
2015-12-15 |
2023-08-13 |
rat |
| Yuxin Liu, Jianghong Yu, Zachary Oaks, Ivan Marchena-Mendez, Lisa Francis, Eduardo Bonilla, Phillip Aleksiejuk, Jessica Patel, Katalin Banki, Steve K Landas, Andras Per. Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus. Clinical immunology (Orlando, Fla.). vol 160. issue 2. 2015-12-15. PMID:26160213. |
liver disease (ld), defined as ≥ 2-fold elevation of aspartate aminotransferase (ast) or alanine aminotransferase (alt), was examined in a longitudinal study of systemic lupus erythematosus (sle) patients. |
2015-12-15 |
2023-08-13 |
Not clear |
| Mansur Mirmohammadlu, Seyed Hojjat Hosseini, Mohammad Kamalinejad, Majid Esmaeili Gavgani, Maryam Noubarani, Mohammad Reza Eskandar. Hypolipidemic, Hepatoprotective and Renoprotective Effects of Cydonia Oblonga Mill. Fruit in Streptozotocin-Induced Diabetic Rats. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 4. 2015-12-15. PMID:26664388. |
the biochemical liver functional tests were also analyzed and it was shown that serum biomarkers of liver dysfunction, including alanine transaminase (alt), aspartate transaminase (ast), and alkaline phosphatase (alp) were significantly reduced in aqueous extract of cydonia oblonga mill. |
2015-12-15 |
2023-08-13 |
rat |
| Ahmet Sert, Cengizhan Kilicaslan, Ece Selma Solak, Sukru Arsla. Mean platelet volume in children with Reye-like syndrome. Platelets. vol 26. issue 3. 2015-12-14. PMID:25806657. |
white blood cell (wbc) count, aspartate transaminase (ast) and alanine transaminase (alt) values were significantly higher and mpv values were significantly lower in patients with rls at an early stage of illness when compared to controls. |
2015-12-14 |
2023-08-13 |
human |
| Jan M Knaak, Vinzent N Spetzler, Nicolas Goldaracena, Markus U Boehnert, Fateh Bazerbachi, Kristine S Louis, Oyedele A Adeyi, Leonid Minkovich, Paul M Yip, Shaf Keshavjee, Gary A Levy, David R Grant, Nazia Selzner, Markus Selzne. Subnormothermic ex vivo liver perfusion reduces endothelial cell and bile duct injury after donation after cardiac death pig liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 20. issue 11. 2015-12-08. PMID:25179693. |
parameters of hepatocyte [aspartate aminotransferase (ast), international normalized ratio (inr), factor v, and caspase 3 immunohistochemistry], endothelial cell (ec; cd31 immunohistochemistry and hyaluronic acid), and biliary injury and function [alkaline phosphatase (alp), total bilirubin, and bile lactate dehydrogenase (ldh)] were determined. |
2015-12-08 |
2023-08-13 |
Not clear |
| Yanhao He, Qiang Liu, Yanxiang Li, Xiaofeng Yang, Weirong Wang, Tingting Li, Wei Zhang, Yuexin Cui, Chaoyun Wang, Rong Li. Protective effects of hydroxysafflor yellow A (HSYA) on alcohol-induced liver injury in rats. Journal of physiology and biochemistry. vol 71. issue 1. 2015-12-08. PMID:25626885. |
hsya treatment ameliorated serum biochemical indicators by reducing the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), hyaluronan (ha), laminin (ln), and type iii precollagen (iii-c) in rats. |
2015-12-08 |
2023-08-13 |
rat |
| Sutthikan Sombattheera, Tanakorn Proungvitaya, Temduang Limpaiboon, Sopit Wongkham, Chaisiri Wongkham, Vor Luvira, Siriporn Proungvitay. Total serum bile acid as a potential marker for the diagnosis of cholangiocarcinoma without jaundice. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 4. 2015-12-08. PMID:25743800. |
liver function parameters such as serum cholesterol, albumin, alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) were also examined. |
2015-12-08 |
2023-08-13 |
Not clear |
| Yan Zhu, Ying Gong, Ruihua Zhu, Xue-Kui Liu, Yu-Ting Sun, Yu Wang, Lu Qi, Jun Lian. Relationship between serum gamma-glutamyltransferase levels and prehypertension in Chinese adults: the cardiometabolic risk in Chinese study. Journal of clinical hypertension (Greenwich, Conn.). vol 16. issue 10. 2015-12-04. PMID:25113653. |
blood pressure, body mass index (bmi), and levels of ggt, fasting blood glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt), and lipid indicators were measured. |
2015-12-04 |
2023-08-13 |
Not clear |
| K G Lisenko, E F Andrade, R V Lobato, D R Orlando, D H C Damin, A C Costa, R R Lima, R R Alvarenga, M G Zangeronimo, R V Sousa, L J Pereir. Metabolic parameters in rats receiving different levels of oral glycerol supplementation. Journal of animal physiology and animal nutrition. vol 99. issue 2. 2015-12-03. PMID:24996054. |
there was a beneficial effect (p < 0.05) up to a dose of 800 mg/kg glycerol on feed intake, percentage of carcass fat, plasma levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), high-density lipoprotein (hdlc) and low-/very low-density lipoprotein (ldlc + vldlc). |
2015-12-03 |
2023-08-13 |
rat |