| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Gauchy, M L Kemel, J Glowinski, M J Besso. In vivo release of endogenously synthesized [3H]GABA from the cat substantia nigra and the pallido-entopeduncular nuclei. Brain research. vol 193. issue 1. 1980-08-25. PMID:7378813. |
halothane anesthetized cats were implanted with push--pull cannulae to study the release of [3h]gaba continuously formed from [3h]glutamine in the substantia nigra (sn) and in the pallido-entopeduncular nuclei (pep). |
1980-08-25 |
2023-08-12 |
cat |
| M F Giorguieff-Chesselet, M J Besson, A Cheramy, J Glowinsk. Role of various amino acids on the modulation of dopamine release from nigro-striatal dopaminergic neurones. Journal de physiologie. vol 75. issue 6. 1980-08-15. PMID:547062. |
when applied to the substantia nigra of the anaesthetized cat by means of a push-pull cannula, gaba induced an increase followed by a transient decrease of 3h-da release in the ipsilateral caudate nucleus; glycine reduced 3h-da release under similar experimental conditions. |
1980-08-15 |
2023-08-11 |
rat |
| K Gale, M J Iadarol. Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition. Science (New York, N.Y.). vol 208. issue 4441. 1980-06-25. PMID:6768130. |
changes in gamma-aminobutyric acid (gaba) occurring in the presence and in the absence of gaba-containing nerve terminals were estimated in rats in which the dense gaba projection to the substantia nigra was surgically destroyed on one side of the brain. |
1980-06-25 |
2023-08-12 |
rat |
| Y Okada, Y Hosoya, H Taniguch. Uptake of 3H-GABA (gamma-aminobutyric acid) and 3H-leucine in the pancreatic islets and substantia nigra of the rat. Experientia. vol 36. issue 1. 1980-05-14. PMID:6987072. |
uptake of 3h-gaba (gamma-aminobutyric acid) and 3h-leucine in the pancreatic islets and substantia nigra of the rat. |
1980-05-14 |
2023-08-12 |
rat |
| A A Grace, B S Bunne. Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. European journal of pharmacology. vol 59. issue 3-4. 1980-04-26. PMID:527646. |
biochemical and electrophysiological and electrophysiological studies suggest that gaba agonists increase the activity of dopaminergic neurons in the zona compacta (zc) of the substantia nigra despite a known gabaergic input to zc cells. |
1980-04-26 |
2023-08-11 |
Not clear |
| A A Grace, B S Bunne. Paradoxical GABA excitation of nigral dopaminergic cells: indirect mediation through reticulata inhibitory neurons. European journal of pharmacology. vol 59. issue 3-4. 1980-04-26. PMID:527646. |
one population of neurons located in the zona reticulata (zr) of the substantia nigra was found to be 20 times more sensitive to iontophoretically applied gaba than zc neurons. |
1980-04-26 |
2023-08-11 |
Not clear |
| E Scarnati, C Forchetti, G Ciancarelli, C Pacitti, A Agnol. Electrophysiological and behavioural correlations during the manipulations of GABA functions in the substantia nigra by n-dipropylacetate and picrotoxin. Pharmacological research communications. vol 11. issue 9. 1980-04-25. PMID:119234. |
electrophysiological and behavioural correlations during the manipulations of gaba functions in the substantia nigra by n-dipropylacetate and picrotoxin. |
1980-04-25 |
2023-08-11 |
Not clear |
| J L Waddington, A L Cros. Pharmacology of (+)- and (-)-baclofen: GABA-dependant rotational behaviour and [3H]GABA receptor binding studies. Neuroscience letters. vol 14. issue 1. 1980-04-23. PMID:231227. |
(+)- and (-)-baclofen were equiactive in inducing contralateral rotational behaviour following their unilateral injection into the zona reticulata of the rat substantia nigra, a proposed gaba-dependent rotational behaviour model, and in displacing the specific binding of [3h]gaba to frozen and thawed membrane preparations of rat brain. |
1980-04-23 |
2023-08-11 |
rat |
| S Govoni, M Memo, L Saiani, P F Spano, M Trabucch. Impairment of brain neurotransmitter receptors in aged rats. Mechanisms of ageing and development. vol 12. issue 1. 1980-04-23. PMID:6243729. |
on the other hand, [3h] gaba binding is significantly decreased in substantia nigra and hypothalamus of aged rats, while it is unmodified in cerebral cortex, cerebellum, striatum and nucleus accumbens. |
1980-04-23 |
2023-08-12 |
rat |
| K Gal. Chronic blockade of dopamine receptors by antischizophrenic drugs enhances GABA binding in substantia nigra. Nature. vol 283. issue 5747. 1980-04-17. PMID:7354838. |
chronic blockade of dopamine receptors by antischizophrenic drugs enhances gaba binding in substantia nigra. |
1980-04-17 |
2023-08-12 |
Not clear |
| M J Iadarola, K Gal. Dissociation between drug-induced increases in nerve terminal and non-nerve terminal pools of GABA in vivo. European journal of pharmacology. vol 59. issue 1-2. 1980-02-26. PMID:389641. |
to examine whether increased gaba levels produced by n-dipropylacetate (dpa) and amino-oxyacetic acid (aoaa) are associated with nerve terminals, we compared the effect of these drugs on the gaba content of substantia nigra (sn) in rats in which the gabaergic afferent projections to sn had been unilaterally destroyed. |
1980-02-26 |
2023-08-11 |
rat |
| J L Waddingto. A methodological weakness in the use of neuroleptic antagonism as a sole criterion for DAergic mediation of drug-induced behavioural effects. European journal of pharmacology. vol 58. issue 3. 1980-02-15. PMID:41722. |
contralateral rotational behavior following unilateral injections of the gaba agonist muscimol (100 ng) or the gaba analogue baclofen (1 microgram) into the zona reticulata of the rat substantia nigra was moderately attenuated by pretreatment with haloperidol (0.4 mg/kg i.p. |
1980-02-15 |
2023-08-11 |
rat |
| S Arbilla, L Kamal, S Z Lange. Presynaptic GABA autoreceptors on GABAergic nerve endings of the rat substantia nigra. European journal of pharmacology. vol 57. issue 2-3. 1979-12-27. PMID:226375. |
presynaptic gaba autoreceptors on gabaergic nerve endings of the rat substantia nigra. |
1979-12-27 |
2023-08-11 |
rat |
| S Arbilla, L Kamal, S Z Lange. Presynaptic GABA autoreceptors on GABAergic nerve endings of the rat substantia nigra. European journal of pharmacology. vol 57. issue 2-3. 1979-12-27. PMID:226375. |
exposure to either muscimol 1 microm or gaba 1 microm inhibited the potassium-evoked release of 3h-gaba from the substantia nigra but not from the occipital cortex. |
1979-12-27 |
2023-08-11 |
rat |
| S Arbilla, L Kamal, S Z Lange. Presynaptic GABA autoreceptors on GABAergic nerve endings of the rat substantia nigra. European journal of pharmacology. vol 57. issue 2-3. 1979-12-27. PMID:226375. |
these results are compatible with the presence of a negative feedback mechanism in bagaergic nerve terminals of the rat substantia nigra which is mediated by presynaptic gaba autoreceptors. |
1979-12-27 |
2023-08-11 |
rat |
| C Llorens-Cortes, H Pollard, J C Schwart. Localization of opiate receptors in substantia nigra evidence by lesion studies. Neuroscience letters. vol 12. issue 2-3. 1979-09-27. PMID:223090. |
from the effects of selective lesions it is concluded that opiate receptors are located on dopamine (da) cell-bodies and/or dendrites as well as on gaba nerve-terminals in substantia nigra. |
1979-09-27 |
2023-08-11 |
Not clear |
| T A James, G L Collingridg. Rapid behavioural and biochemical effects of tetanus toxin microinjected into the substantia nigra: a dual role for GABA? Neuroscience letters. vol 11. issue 2. 1979-09-27. PMID:460688. |
rapid behavioural and biochemical effects of tetanus toxin microinjected into the substantia nigra: a dual role for gaba? |
1979-09-27 |
2023-08-11 |
mouse |
| C Reavill, P Jenner, N Leigh, C D Marsde. Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components. Neuroscience letters. vol 12. issue 2-3. 1979-09-27. PMID:460728. |
turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual gaba components. |
1979-09-27 |
2023-08-11 |
rat |
| C Reavill, P Jenner, N Leigh, C D Marsde. Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components. Neuroscience letters. vol 12. issue 2-3. 1979-09-27. PMID:460728. |
injection of the gaba agonist muscimol into rat caudal substantia nigra caused contralateral turning, whereas injection into the rostral substantia nigra caused ipsilateral turning. |
1979-09-27 |
2023-08-11 |
rat |
| C Reavill, P Jenner, N Leigh, C D Marsde. Turning behaviour induced by injection of muscimol or picrotoxin into the substantia nigra demonstrates dual GABA components. Neuroscience letters. vol 12. issue 2-3. 1979-09-27. PMID:460728. |
these findings support the hypothesis that gaba has dual actions in the substantia nigra. |
1979-09-27 |
2023-08-11 |
rat |