| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Simler, L Ciesielski, J Clement, P Mande. Amino acid neurotransmitter alterations in three sublines of Rb mice differing by their susceptibility to audiogenic seizures. Neurochemical research. vol 15. issue 7. 1990-10-11. PMID:1975652. |
seizure severity (rb1/rb2) seems to correlate, in some areas, with additional lower amounts of gaba already reported and, to a lower extent, of asp (-19% in striatum, inferior colliculus and cerebellum), of tau and gly; a tendency for a rise in gln content was observed in certain others (10-20% in olfactory bulb, thalamus, hypothalamus, substantia nigra, and frontal, temporal and occipital cortex). |
1990-10-11 |
2023-08-11 |
mouse |
| A M Young, P M Foley, H F Bradfor. Preloading in vivo: a rapid and reliable method for measuring gamma-aminobutyric acid and glutamate fluxes by microdialysis. Journal of neurochemistry. vol 55. issue 3. 1990-09-17. PMID:1974602. |
in vivo microdialysis was used in conjunction with a novel dual-label preloading method, to monitor changes in extracellular levels of gamma-aminobutyric acid (gaba) and glutamate in the striatum of conscious, unrestrained rats. |
1990-09-17 |
2023-08-11 |
rat |
| M Raiteri, M Marchi, P Paudice, A Pittalug. Muscarinic receptors mediating inhibition of gamma-aminobutyric acid release in rat corpus striatum and their pharmacological characterization. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:2384883. |
muscarinic receptors mediating inhibition of gamma-aminobutyric acid release in rat corpus striatum and their pharmacological characterization. |
1990-09-17 |
2023-08-11 |
rat |
| M Raiteri, M Marchi, P Paudice, A Pittalug. Muscarinic receptors mediating inhibition of gamma-aminobutyric acid release in rat corpus striatum and their pharmacological characterization. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:2384883. |
the effects of acetylcholine (ach) and of cholinergic agonists on the release of tritiated gamma-aminobutyric acid ([3h]gaba) were studied in superfused synaptosomes prepared from rat corpus striatum and prelabeled with the radioactive amino acid. |
1990-09-17 |
2023-08-11 |
rat |
| M Y Zhang, T Hashimoto, K Kuriyam. Stress induced alterations in striatal GABAA receptor complex. Japanese journal of pharmacology. vol 53. issue 1. 1990-07-13. PMID:2161962. |
the effect of cold-immobilized stress on the gamma-aminobutylic acid (gaba)/benzodiazepine (bzp) receptor complex in the rat striatum was examined. |
1990-07-13 |
2023-08-11 |
rat |
| K Nakamura, T Matsumoto, M Hirano, H Uchimur. Changes in GABA content and turnover in discrete regions of rat brain after systemic administration of caerulein. Psychopharmacology. vol 101. issue 1. 1990-06-27. PMID:2343075. |
caerulein decreased gaba levels in the nucleus accumbens, tuberculum olfactorium and substantia nigra and diminished gaba turnover rates in the striatum, nucleus accumbens and substantia nigra, as estimated from the rate of gaba accumulation after inhibition of gaba transaminase by aminooxyacetic acid (aoaa). |
1990-06-27 |
2023-08-11 |
rat |
| R D O'Neil. Uric acid levels and dopamine transmission in rat striatum: diurnal changes and effects of drugs. Brain research. vol 507. issue 2. 1990-06-20. PMID:2337766. |
the unilateral infusion of gamma-aminobutyric acid, taurine and haloperidol into the substantia nigra caused increases in the height of both the uric acid and hva peak in the ipsilateral striatum; the size of these changes showed a significant correlation. |
1990-06-20 |
2023-08-11 |
rat |
| M Virgili, O Barnabei, A Contestabil. Regional maturation of neurotransmitter-related and glial markers during postnatal development in the rat. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 2. 1990-05-24. PMID:1970217. |
neurotransmitter-related (choline acetyltransferase, acetylcholinesterase, glutamate decarboxylase, l-glutamate and gaba high affinity uptake) and glial neurochemical markers (glutamine synthetase, beta-alanine uptake and 2',3' cyclic nucleotide phosphohydrolase) have been quantitatively assayed in various regions of the rat cns during normal postnatal development: spinal cord, cerebellum, superior colliculus, hippocampus, striatum, visual cortex, frontal sensory-motor cortex and prefrontal cortex. |
1990-05-24 |
2023-08-11 |
rat |
| K Hellevuo, K Kiianma. GABA turnover in the brain of rat lines developed for differential ethanol-induced motor impairment. Pharmacology, biochemistry, and behavior. vol 34. issue 4. 1990-03-27. PMID:2623044. |
the saline-treated ant rats were found to have a higher concentration of gaba in the striatum and a higher rate of gaba accumulation in the cerebellum than the at rats. |
1990-03-27 |
2023-08-11 |
rat |
| M F Beal, N W Kowall, K J Swartz, R J Ferrant. Homocysteic acid lesions in rat striatum spare somatostatin-neuropeptide Y (NADPH-diaphorase) neurons. Neuroscience letters. vol 108. issue 1-2. 1990-03-19. PMID:1689475. |
increasing doses of l-hca injected into the anterior striatum resulted in dose-dependent reductions in both substance p-like immunoreactivity (sp-li) and gamma-aminobutyric acid (gaba) while there was a relative sparing of both somatostatin-like immunoreactivity (ss-li) and neuropeptide y-like immunoreactivity (npy-li). |
1990-03-19 |
2023-08-11 |
rat |
| H Nagaham. Acute and long-lasting effects of peripheral injection of caerulein and CCK-8 on the central GABAergic system in mice. Peptides. vol 10. issue 6. 1990-03-19. PMID:2622803. |
the content and accumulation of gaba in the striatum, hypothalamus, and frontal cortex was measured with high performance liquid chromatography with electrochemical detection (hplc-ecd). |
1990-03-19 |
2023-08-11 |
mouse |
| H Nagaham. Acute and long-lasting effects of peripheral injection of caerulein and CCK-8 on the central GABAergic system in mice. Peptides. vol 10. issue 6. 1990-03-19. PMID:2622803. |
the gaba content slightly decreased in the striatum 60 min after cln and cck-8 were administered, whereas it slightly increased in the hypothalamus and frontal cortex. |
1990-03-19 |
2023-08-11 |
mouse |
| H Nagaham. Acute and long-lasting effects of peripheral injection of caerulein and CCK-8 on the central GABAergic system in mice. Peptides. vol 10. issue 6. 1990-03-19. PMID:2622803. |
moreover, with cln and cck-8, the gaba accumulation after aoaa treatment decreased in the striatum and hypothalamus 30 min after injection. |
1990-03-19 |
2023-08-11 |
mouse |
| H Nagaham. Acute and long-lasting effects of peripheral injection of caerulein and CCK-8 on the central GABAergic system in mice. Peptides. vol 10. issue 6. 1990-03-19. PMID:2622803. |
meanwhile, when administering cln, the gaba content as well as the gaba accumulation after aoaa treatment increased in the striatum and frontal cortex 1 day after injection, and continued to increase the second and third day in the striatum. |
1990-03-19 |
2023-08-11 |
mouse |
| H S Pan, T M Engber, T N Chase, J R Walter. The effects of striatal lesion on turning behavior and globus pallidus single unit response to dopamine agonist administration. Life sciences. vol 46. issue 1. 1990-03-02. PMID:2299971. |
both the extent of attenuation of the electrophysiological response of pallidal neurons in lesioned animals and the neurotoxin-induced decreases in choline acetyltransferase activity and gaba content in the caudal striatum were correlated with the degree of apomorphine-induced turning. |
1990-03-02 |
2023-08-11 |
rat |
| W Lösche. Valproate enhances GABA turnover in the substantia nigra. Brain research. vol 501. issue 1. 1989-12-20. PMID:2508993. |
however, significant increases in gaba accumulation were found in corpus striatum and, more marked, in substantia nigra. |
1989-12-20 |
2023-08-11 |
rat |
| E Sanna, M Serra, S Pepitoni, G Biggi. Dramatic increase in nigral t-[35S]butylbicyclophosphorothionate binding sites elicited by the degeneration of the striato-nigral GABAergic pathway: reversal by diazepam. Brain research. vol 501. issue 1. 1989-12-20. PMID:2553212. |
in rats, the degeneration of the striato-nigral gabaergic pathway caused by the intrastriatal injection of kainic acid induced a marked decrease (65%) of gaba content and glutamic acid decarboxylase (gad) activity and a dramatic increase (225%) in the binding of t-[35s]butylbicyclophosphorothionate [( 35s]tbps) to a membrane preparation from the substantia nigra homolateral to the injected striatum. |
1989-12-20 |
2023-08-11 |
rat |
| A J Cross, J M Stirling, T N Robinson, D M Bowen, P T Francis, A R Gree. The modulation by chlormethiazole of the GABAA-receptor complex in rat brain. British journal of pharmacology. vol 98. issue 1. 1989-12-19. PMID:2553191. |
chlormethiazole had no effect on gaba synthesis in the cortex, hippocampus and striatum or on gaba release from cortical slices in vitro. |
1989-12-19 |
2023-08-11 |
rat |
| V R Kolluri, G Y Lakshm. Changes in regional levels of putative neurotransmitter amino acids in brain under unilateral forebrain ischemia. Neurochemical research. vol 14. issue 7. 1989-10-20. PMID:2571093. |
no changes in gaba levels were found in striatum. |
1989-10-20 |
2023-08-11 |
Not clear |
| M Ikeda, M Mikuni, T Nishikawa, K Takahash. A neurochemical study of a new mutant mouse presenting myoclonus-like involuntary movement: a possible model of spontaneous serotonergic hyperactivity. Brain research. vol 495. issue 2. 1989-10-12. PMID:2765934. |
gaba was increased in the striatum. |
1989-10-12 |
2023-08-11 |
mouse |