| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K F Greif, N J Tillakaratne, M G Erlander, S Feldblum, A J Tobi. Transient increase in expression of a glutamate decarboxylase (GAD) mRNA during the postnatal development of the rat striatum. Developmental biology. vol 153. issue 1. 1992-10-07. PMID:1516745. |
we have examined the expression of these two forms of gad during postnatal development of the rat striatum to determine whether different classes of gaba neurons selectively express different amounts of the two gad mrnas. |
1992-10-07 |
2023-08-11 |
human |
| J J Soghomonian, C Gonzales, M F Chessele. Messenger RNAs encoding glutamate-decarboxylases are differentially affected by nigrostriatal lesions in subpopulations of striatal neurons. Brain research. vol 576. issue 1. 1992-10-06. PMID:1515913. |
dopaminergic nigrostriatal neurons constitute one of the major inputs to the striatum, and play a role in the regulation of gamma-aminobutyric acid (gaba) and glutamic acid decarboxylase (gad), the gaba-synthesizing enzyme, in striatal neurons. |
1992-10-06 |
2023-08-11 |
rat |
| W Löscher, U Wahnschaffe, C Rundfeldt, D Hönack, H O Hoppe. Regional alterations in brain amino acids during the estrous cycle of the rat. Neurochemical research. vol 17. issue 10. 1992-09-24. PMID:1508307. |
a decreased glutamate level during proestrus was also found in thalamus, while both glutamate and gaba did not vary throughout estrous cycle in any of the other examined regions, including substantia nigra, amygdala, striatum, cortex and hippocampus. |
1992-09-24 |
2023-08-11 |
rat |
| J P Bolam, Y Smit. The striatum and the globus pallidus send convergent synaptic inputs onto single cells in the entopeduncular nucleus of the rat: a double anterograde labelling study combined with postembedding immunocytochemistry for GABA. The Journal of comparative neurology. vol 321. issue 3. 1992-09-22. PMID:1380517. |
the striatum and the globus pallidus send convergent synaptic inputs onto single cells in the entopeduncular nucleus of the rat: a double anterograde labelling study combined with postembedding immunocytochemistry for gaba. |
1992-09-22 |
2023-08-11 |
rat |
| J P Bolam, Y Smit. The striatum and the globus pallidus send convergent synaptic inputs onto single cells in the entopeduncular nucleus of the rat: a double anterograde labelling study combined with postembedding immunocytochemistry for GABA. The Journal of comparative neurology. vol 321. issue 3. 1992-09-22. PMID:1380517. |
in order to examine the chemical nature of the input to the entopeduncular nucleus from the globus pallidus and the striatum, ultrathin sections were immunostained by the postembedding method to reveal endogenous gaba. |
1992-09-22 |
2023-08-11 |
rat |
| W T O'Connor, S Tanganelli, U Ungerstedt, K Fux. The effects of neurotensin on GABA and acetylcholine release in the dorsal striatum of the rat: an in vivo microdialysis study. Brain research. vol 573. issue 2. 1992-09-18. PMID:1504761. |
the effects of neurotensin on gaba and acetylcholine release in the dorsal striatum of the rat: an in vivo microdialysis study. |
1992-09-18 |
2023-08-11 |
rat |
| G B Acosta, M E Otero Losada, M C Rubi. Changes in GABAergic function after chronic chemical stress. General pharmacology. vol 23. issue 2. 1992-09-03. PMID:1639239. |
chronic stress: (a) reduced neuronal uptake of [3h] -gaba in the frontal cerebral cortex (43%) and increased non-neuronal uptake of [3h] -gaba in the hypothalamus (62%); (b) enhanced the activity of gad (under subsaturating substrate concentration) in the frontal cortex (91%) and in the corpus striatum (69%); (c) did not modify gaba endogenous concentration; (d) did not affect the animals' body weight increase or produce any signs of toxicity. |
1992-09-03 |
2023-08-11 |
rat |
| W Löscher, D Hörsterman. Abnormalities in amino acid neurotransmitters in discrete brain regions of genetically dystonic hamsters. Journal of neurochemistry. vol 59. issue 2. 1992-08-20. PMID:1352802. |
in dtsz hamsters with the maximum severity of dystonia, significant changes in concentrations of the neurotransmitters gamma-aminobutyric acid, glutamate, aspartate, and taurine were found in several regions involved in motor functions, e.g., cerebellum, thalamus, and corpus striatum. |
1992-08-20 |
2023-08-11 |
Not clear |
| J J Soghomonian, M F Chessele. Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat. Synapse (New York, N.Y.). vol 11. issue 2. 1992-08-10. PMID:1626311. |
the neurotransmitter gamma-aminobutyric acid (gaba) is present in efferent neurons of the striatum and of the pallidum, one of the main striatal target areas. |
1992-08-10 |
2023-08-11 |
rat |
| S Tanganelli, K Fuxe, L Ferraro, A M Janson, C Bianch. Inhibitory effects of the psychoactive drug modafinil on gamma-aminobutyric acid outflow from the cerebral cortex of the awake freely moving guinea-pig. Possible involvement of 5-hydroxytryptamine mechanisms. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 4. 1992-07-31. PMID:1620245. |
the involvement of 5-ht mechanisms in the inhibitory action of modafinil on cortical gaba release is also suggested by the findings that 5-ht metabolism may become increased by modafinil at least in the striatum. |
1992-07-31 |
2023-08-11 |
mouse |
| P Mialon, R Gibey, J C Bigot, L Barthelem. Changes in striatal and cortical amino acid and ammonia levels of rat brain after one hyperbaric oxygen-induced seizure. Aviation, space, and environmental medicine. vol 63. issue 4. 1992-07-22. PMID:1610339. |
after hbo seizure, aa levels (except for gamma-amino butyric acid, gaba, and glutamine), with respect to 6 ata air levels, were altered in the striatum with a concomitant rise in ammonia (+70%) at variance with the cortex. |
1992-07-22 |
2023-08-11 |
rat |
| M Mercugliano, C F Saller, A I Salama, D C U'Prichard, M F Chessele. Clozapine and haloperidol have differential effects on glutamic acid decarboxylase mRNA in the pallidal nuclei of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 6. issue 3. 1992-07-10. PMID:1599608. |
in situ hybridization histochemistry was used to quantify the levels of labeling for the messenger ribonucleic acid encoding glutamic acid decarboxylase, the main synthesizing enzyme for gaba in neurons of the striatum, globus pallidus, and entopeduncular nucleus. |
1992-07-10 |
2023-08-11 |
rat |
| L Kerkerian-Le Goff, C Forni, D Samuel, A Bloc, N Dusticier, A Nieoullo. Intracerebroventricular administration of neuropeptide Y affects parameters of dopamine, glutamate and GABA activities in the rat striatum. Brain research bulletin. vol 28. issue 2. 1992-07-07. PMID:1596740. |
intracerebroventricular administration of neuropeptide y affects parameters of dopamine, glutamate and gaba activities in the rat striatum. |
1992-07-07 |
2023-08-11 |
rat |
| L Kerkerian-Le Goff, C Forni, D Samuel, A Bloc, N Dusticier, A Nieoullo. Intracerebroventricular administration of neuropeptide Y affects parameters of dopamine, glutamate and GABA activities in the rat striatum. Brain research bulletin. vol 28. issue 2. 1992-07-07. PMID:1596740. |
the effects of intracerebroventricular (icv) injection of neuropeptide y (npy) on parameters of dopamine (da), glutamate (glu) and gamma-aminobutyric acid (gaba) activities were investigated in the rat striatum. |
1992-07-07 |
2023-08-11 |
rat |
| L Kerkerian-Le Goff, C Forni, D Samuel, A Bloc, N Dusticier, A Nieoullo. Intracerebroventricular administration of neuropeptide Y affects parameters of dopamine, glutamate and GABA activities in the rat striatum. Brain research bulletin. vol 28. issue 2. 1992-07-07. PMID:1596740. |
these results indicate that npy may be involved in regulating the activity of nigral dopaminergic and cortical glutamatergic afferent pathways and that of intrinsic gaba neurons in the rat striatum. |
1992-07-07 |
2023-08-11 |
rat |
| C Yamamoto, E Kawan. Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Okajimas folia anatomica Japonica. vol 68. issue 5. 1992-05-12. PMID:1806845. |
immunohistochemical detection of gaba in rat striatum by intraperitoneal injection of mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). |
1992-05-12 |
2023-08-11 |
rat |
| C Yamamoto, E Kawan. Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Okajimas folia anatomica Japonica. vol 68. issue 5. 1992-05-12. PMID:1806845. |
gaba is induced in the striatum of 4 mptp (30 mg/kg) i.p. |
1992-05-12 |
2023-08-11 |
rat |
| C Yamamoto, E Kawan. Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Okajimas folia anatomica Japonica. vol 68. issue 5. 1992-05-12. PMID:1806845. |
the results give some insight as to how da and gaba function within the striatum with respect to the development of neuronal abnormalities. |
1992-05-12 |
2023-08-11 |
rat |
| C Yamamoto, E Kawan. Immunohistochemical detection of GABA in rat striatum by intraperitoneal injection of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Okajimas folia anatomica Japonica. vol 68. issue 5. 1992-05-12. PMID:1806845. |
the activity within the striatum can be followed with immunohistochemical technique for gaba morphologically. |
1992-05-12 |
2023-08-11 |
rat |
| B A Reynolds, S Weis. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science (New York, N.Y.). vol 255. issue 5052. 1992-04-30. PMID:1553558. |
newly generated cells with neuronal morphology were immunoreactive for gamma-aminobutyric acid and substance p, two neurotransmitters of the adult striatum in vivo. |
1992-04-30 |
2023-08-11 |
mouse |