| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Arvin, D Lekieffre, J L Graham, C Moncada, A G Chapman, B S Meldru. Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia. Journal of neurochemistry. vol 62. issue 4. 1994-04-20. PMID:7907651. |
administration of gyki 52466 (10 mg/kg bolus + 10 mg/kg/60 min intravenously starting 20 min before onset of ischaemia) inhibited ischaemia-induced increases in microdialysate glutamate and gaba in striatum without affecting the increases in hippocampus or cortex. |
1994-04-20 |
2023-08-12 |
rat |
| B Arvin, D Lekieffre, J L Graham, C Moncada, A G Chapman, B S Meldru. Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischaemia. Journal of neurochemistry. vol 62. issue 4. 1994-04-20. PMID:7907651. |
at 72 h, after the ischaemic period, significantly reduced gaba levels were observed in striatum and hippocampus. |
1994-04-20 |
2023-08-12 |
rat |
| Q Y L. [Effects of GABA and substance P on metabolism of striatal dopamine following experimental cerebral ischemia]. Zhonghua yi xue za zhi. vol 73. issue 11. 1994-04-12. PMID:7510213. |
using both the ria and hplc-ec methods, we studied the effect of intrastriatal injection of bicuculline (bic), a gaba antagonist as well as the intranigral injection of [d-arg1, d-phe5, d-trp7-9, leu11] substance p, the sp antagonist on the metabolism of dopamine (da) at the striatum after the unilateral irreversible occlusion of the right middle cerebral artery (mcao) of rats. |
1994-04-12 |
2023-08-12 |
rat |
| Q Y L. [Effects of GABA and substance P on metabolism of striatal dopamine following experimental cerebral ischemia]. Zhonghua yi xue za zhi. vol 73. issue 11. 1994-04-12. PMID:7510213. |
the above effects of intrastriatal bic on da and its metabolites were completely reversed with an intranigral injection of 5 nmol of substance p. it is suggested that the effect of intrastriatal bic on da metabolites in the striatum is mediated by substance p in the substantia nigra and that the regulatory effect of gaba and sp on striatal da is working in middle cerebral artery occlusion. |
1994-04-12 |
2023-08-12 |
rat |
| H Nishino, N Aihara, A Czurko, T Hashitani, Y Isobe, O Ichikawa, H Watar. Reconstruction of GABAergic transmission and behavior by striatal cell grafts in rats with ischemic infarcts in the middle cerebral artery. Journal of neural transplantation & plasticity. vol 4. issue 2. 1994-03-31. PMID:8110865. |
fetal striatal cell suspensions were grafted stereotaxically into the infarcted striatum of rats, and reconstruction of striatopallidal gaba transmission and behavior were investigated. |
1994-03-31 |
2023-08-12 |
rat |
| M Remiszewska, Z Jastrzebski, H Czyzewska-Szafran, M Wutkiewic. Enhancement of GABAergic system activity by metoprolol in spontaneously hypertensive rats. European journal of pharmacology. vol 250. issue 3. 1994-03-31. PMID:8112395. |
the measurements of gamma-aminobutyric acid (gaba) synthesis and specific [3h]gaba binding were performed in the hypothalamus, the pons-medulla, the hippocampus and the striatum. |
1994-03-31 |
2023-08-12 |
rat |
| Y Uchiyama-Tsuyuki, H Araki, T Yae, S Otom. Changes in the extracellular concentrations of amino acids in the rat striatum during transient focal cerebral ischemia. Journal of neurochemistry. vol 62. issue 3. 1994-03-28. PMID:8113794. |
accordingly, our study was undertaken to examine the patterns of changes of extracellular glutamate, aspartate, gaba, taurine, glutamine, alanine, and phosphoethanolamine in the striatum of transient focal cerebral ischemia, as evidence to support their pathogenic roles. |
1994-03-28 |
2023-08-12 |
rat |
| N Grégoire, F Lebrun, L Fahn, G Salamon, J Nicol. A study of GABAergic system in Scrapie-infected hamsters after striatal microinoculation of the agent. Neuroscience letters. vol 163. issue 2. 1994-03-17. PMID:8309620. |
the binding of [3h]gaba (scatchard analysis) to cerebral membranes does not seem to be altered either at the local site of agent inoculation (striatum) neither at distance in the cerebellum: the affinity constant (kd) to the ligand and the maximal number of receptor sites were of the same magnitude in control and scrapie animals, but we do not have a statistical analysis. |
1994-03-17 |
2023-08-12 |
Not clear |
| N Grégoire, F Lebrun, L Fahn, G Salamon, J Nicol. A study of GABAergic system in Scrapie-infected hamsters after striatal microinoculation of the agent. Neuroscience letters. vol 163. issue 2. 1994-03-17. PMID:8309620. |
the present study was focused on the effects of scrapie agent directly injected into striatum on gaba neurons at the presynaptic level (gaba uptake) and at the postsynaptic level (gabaa receptors). |
1994-03-17 |
2023-08-12 |
Not clear |
| N Grégoire, F Lebrun, L Fahn, G Salamon, J Nicol. A study of GABAergic system in Scrapie-infected hamsters after striatal microinoculation of the agent. Neuroscience letters. vol 163. issue 2. 1994-03-17. PMID:8309620. |
the high-affinity [3h]gaba uptake is not changed in the scrapie-injected striatum neither in the controlateral site and the kinetics (km, vmax) values are not statistically different for control and scrapie-inoculated animals. |
1994-03-17 |
2023-08-12 |
Not clear |
| C L Veenman, A Reine. The distribution of GABA-containing perikarya, fibers, and terminals in the forebrain and midbrain of pigeons, with particular reference to the basal ganglia and its projection targets. The Journal of comparative neurology. vol 339. issue 2. 1994-03-04. PMID:8300906. |
in the basal ganglia, numerous medium-sized neurons throughout the striatum were labeled for gaba, while pallidal neurons, as well as a small population of large, aspiny striatal neurons, labeled for gad and gaba. |
1994-03-04 |
2023-08-12 |
pigeon |
| N Lindefor. Dopaminergic regulation of glutamic acid decarboxylase mRNA expression and GABA release in the striatum: a review. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278600. |
increased dopaminergic transmission by repeated but not single doses of amphetamine is followed by decreased striatal gaba release and decreased gad67 mrna expression in a subpopulation of medium-sized neurons in the striatum. |
1994-02-08 |
2023-08-12 |
Not clear |
| N Lindefor. Dopaminergic regulation of glutamic acid decarboxylase mRNA expression and GABA release in the striatum: a review. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278600. |
the majority of neurons in the striatum (caudate-putamen, dorsal striatum; nucleus accumbens, ventral striatum) and in striatal projection regions (the pallidum, the entopeduncular nucleus and substantia nigra reticulata) use gamma-aminobutyric acid (gaba) as transmitter and express glutamic acid decarboxylase (gad; rate limiting enzyme) in the synthesis of gaba. |
1994-02-08 |
2023-08-12 |
Not clear |
| N Lindefor. Dopaminergic regulation of glutamic acid decarboxylase mRNA expression and GABA release in the striatum: a review. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278600. |
two populations of medium-sized gaba neurons in the striatum seem to be under tonic dopaminergic influence. |
1994-02-08 |
2023-08-12 |
Not clear |
| N Lindefor. Dopaminergic regulation of glutamic acid decarboxylase mRNA expression and GABA release in the striatum: a review. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278600. |
dopaminergic regulation of glutamic acid decarboxylase mrna expression and gaba release in the striatum: a review. |
1994-02-08 |
2023-08-12 |
Not clear |
| N Lindefor. Dopaminergic regulation of glutamic acid decarboxylase mRNA expression and GABA release in the striatum: a review. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 6. 1994-02-08. PMID:8278600. |
inhibition of dopaminergic transmission in the striatum by lesion of dopamine neurons or by neuroleptic treatment is followed by an increased release of gaba and increased expression of gad67 mrna in a subpopulation of striatal medium-sized neurons which project to the globus pallidus, and increased striatal gad enzyme activity. |
1994-02-08 |
2023-08-12 |
Not clear |
| A Reiner, K D Anderso. Co-occurrence of gamma-aminobutyric acid, parvalbumin and the neurotensin-related neuropeptide LANT6 in pallidal, nigral and striatal neurons in pigeons and monkeys. Brain research. vol 624. issue 1-2. 1994-01-13. PMID:8252409. |
immunohistochemical double-labeling techniques were used to examine the co-localization of the neurotransmitter gamma-aminobutyric acid (gaba), the calcium-binding protein parvalbumin and the neurotensin-related hexapeptide lant6 in neurons of the striatum and its target areas in pigeons and monkeys. |
1994-01-13 |
2023-08-12 |
monkey |
| N R Sim. The stimulus-evoked release of glutamate and GABA from brain subregions following transient forebrain ischemia in the rat. Neurochemical research. vol 18. issue 10. 1994-01-07. PMID:7902957. |
the release of glutamate and gaba in response to k+ depolarization was determined for tissue prisms prepared from brain subregions removed from rats following 30 min of forebrain ischemia or recirculation periods up to 24 h. there were statistically significant effects of this treatment on release of both amino acids from samples of the dorsolateral striatum, an area developing selective neuronal degeneration. |
1994-01-07 |
2023-08-12 |
rat |
| N R Sim. The stimulus-evoked release of glutamate and GABA from brain subregions following transient forebrain ischemia in the rat. Neurochemical research. vol 18. issue 10. 1994-01-07. PMID:7902957. |
these results suggest that changes in the ability to release glutamate and gaba in response to stimulation are not necessary for the development of neurodegeneration in the striatum but rather that release of these amino acids may be modified as a result of the degenerative process. |
1994-01-07 |
2023-08-12 |
rat |
| H Nishino, K Koide, N Aihara, M Kumazaki, T Sakurai, H Naga. Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance. Brain research bulletin. vol 32. issue 5. 1993-12-07. PMID:8221145. |
striatal grafts in the ischemic striatum improve pallidal gaba release and passive avoidance. |
1993-12-07 |
2023-08-12 |
rat |