| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Fuxe, L F Agnati, U Ungersted. The effect of mepiprazole on central monoamine neurons. Evidence for increased 5-hydroxytryptamine and dopamine receptor activity. European journal of pharmacology. vol 35. issue 1. 1976-06-02. PMID:943291. |
a certain direct activation of spinal 5-ht receptors may also be involved, since the actions of pap in the spinal cord were independent of presynaptic 5-ht stores. |
1976-06-02 |
2023-08-11 |
rat |
| J A Zivin, J L Doppman, J L Reid, M L Tappaz, J M Saavedra, I J Kopin, D M Jacobowit. Biochemical and histochemical studies of biogenic amines in spinal cord trauma. Neurology. vol 26. issue 2. 1976-04-30. PMID:943073. |
highly sensitive enzymatic assays, microdissection techniques, and histochemical methods were used to investigate the effects of blunt trauma on rabbit spinal cord serotonin, norepinephrine, and dopamine concentrations. |
1976-04-30 |
2023-08-11 |
rabbit |
| J A Zivin, J L Doppman, J L Reid, M L Tappaz, J M Saavedra, I J Kopin, D M Jacobowit. Biochemical and histochemical studies of biogenic amines in spinal cord trauma. Neurology. vol 26. issue 2. 1976-04-30. PMID:943073. |
substantial changes in monoamines do occur after spinal cord trauma and serotonin may play a role in injury development. |
1976-04-30 |
2023-08-11 |
rabbit |
| D A Pasquier, G Balfago. Regional distribution of 5-hydroxytryptamine in cat brain. Revista espanola de fisiologia. vol 31. issue 4. 1976-04-29. PMID:1215624. |
serotonin decreased gradually at the mesencephalon, preoptic area, medulla oblongata, hippocampus, pons, visual cortex, spinal cord and frontal cortex. |
1976-04-29 |
2023-08-11 |
cat |
| V Chan-Pala. Serotonin axons in the supra- and subependymal plexuses and in the leptomeninges; their roles in local alterations of cerebrospinal fluid and vasomotor activity. Brain research. vol 102. issue 1. 1976-04-27. PMID:813816. |
extensive plexuses of serotonin axons form a supra- and subependymal system in the walls of the ventricles, in the arachnoid sheath around major cerebral blood vessels, and in the pia over the spinal cord. |
1976-04-27 |
2023-08-11 |
rat |
| M Bacon, J Blig. Interaction between the effects of spinal heating and cooling and of injections into a lateral cerebral ventricle of noradrenaline, 5-hydroxytryptamine and carbachol on thermoregulation in sheep. The Journal of physiology. vol 254. issue 1. 1976-04-15. PMID:1249731. |
a study has been made of the interactions of the thermoregulatory effects of spinal cord heating and cooling and of the injections into the cerebral ventricle of noradrenaline, 5-hydroxytryptamine (5-ht) and carbamylcholine in sheep. |
1976-04-15 |
2023-08-11 |
Not clear |
| M Bacon, J Blig. Interaction between the effects of spinal heating and cooling and of injections into a lateral cerebral ventricle of noradrenaline, 5-hydroxytryptamine and carbachol on thermoregulation in sheep. The Journal of physiology. vol 254. issue 1. 1976-04-15. PMID:1249731. |
the interactions of spinal cord heating and the injections into the cerebral ventricle of noradrenaline, 5-ht and carbamylcholine were very similar to those of hypothalamic heating or of high ambient temperature and the injections into the cerebral ventricle of these substances. |
1976-04-15 |
2023-08-11 |
Not clear |
| P M Headley, D Lodg. The effects of beta-carbolines on responses to acetylcholine, noradrenaline, 5-hydroxytryptamine and amino acids in the rat spinal cord. Brain research. vol 101. issue 3. 1976-03-15. PMID:1244986. |
the effects of beta-carbolines on responses to acetylcholine, noradrenaline, 5-hydroxytryptamine and amino acids in the rat spinal cord. |
1976-03-15 |
2023-08-11 |
rat |
| A Björklund, H G Baumgarten, L Lachenmayer, E Rosengre. Recovery of brain noradrenaline after 5,7-dihydroxytryptamine-induced axonal lesions in the rat. Cell and tissue research. vol 161. issue 2. 1975-12-30. PMID:1175203. |
following a substantial depletion of both amines in all cns regions (telodiencephalon, brainstem and spinal cord) at 10 days after 150 mug 5,7-dht, brain na--but not 5-ht--levels recovered to near-normal values in brainstem and forebrain (35% below the age-matched controls) within 4 months. |
1975-12-30 |
2023-08-11 |
rat |
| R Sjöström, J Ekstedt, E Anggår. Concentration gradients of monoamine metabolites in human cerebrospinal fluid. Journal of neurology, neurosurgery, and psychiatry. vol 38. issue 7. 1975-12-04. PMID:1159438. |
the results suggest that lumbar hva reflects dopaminergic activity in the brain, whereas lumbar 5-hiaa and hmpg/vma reflect the activity of 5-hydroxytryptamine and noradrenaline secreting neurones in both the brain and the spinal cord. |
1975-12-04 |
2023-08-11 |
human |
| E S Stanton, P M Smolen, B S Nashold, D A Dreyer, J N Davi. Segmental analysis of spinal cord monoamines after thoracic transection in the dog. Brain research. vol 89. issue 1. 1975-11-08. PMID:1056806. |
the noradrenaline, dopamine and serotonin content from 10 segments of the dog spinal cord before and after a t7 transection were measured. |
1975-11-08 |
2023-08-11 |
rat |
| S Barasi, M H Robert. The modification of lumbar motoneurone excitability by stimulation of a putative 5-hydroxytryptamine pathway. British journal of pharmacology. vol 52. issue 3. 1975-07-28. PMID:4458843. |
it is suggested that activity within the raphe-spinal pathway can increase lumbar motoneurone excitability via the release of 5-ht in the ventral horn of the spinal cord. |
1975-07-28 |
2023-08-11 |
rat |
| E Sanders-Bush, J A Bushing, F Sulse. Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms. The Journal of pharmacology and experimental therapeutics. vol 192. issue 1. 1975-07-01. PMID:1123726. |
the greatest reductions of 5-ht, tryptophan hydroxylase activity and synaptosomal uptake were found in the midbrain, hippocampus and striatum with less pronounced effects in the hypothalamus, medulla-pons and spinal cord. |
1975-07-01 |
2023-08-11 |
rat |
| F A Newman, R D Strauss, S E Reznick, M E Bortolussi, M J Cummins, J H Stucke. The effect of high cervical cordotomy on portal vein plasma serotonin and 5-hydroxyindoleacetic acid levels in dogs with and without superior mesenteric artery occlusion. Surgery. vol 77. issue 1. 1975-03-14. PMID:1053683. |
these findings indicate (1) that maintenance of the normal plasma 5-ht level in portal vein blood in this experimental model is dependent on the integrity of the spinal cord and (2) that sma occlusion in animals with a high cervical cordotomy does not result in further changes in the plasma 5-ht level in portal vein blood. |
1975-03-14 |
2023-08-11 |
Not clear |
| L G Nygren, K Fuxe, G Jonsson, L Olso. Functional regeneration of 5-hydroxytryptamine nerve terminals in the rat spinal cord following 5, 6-dihydroxytryptamine induced degeneration. Brain research. vol 78. issue 3. 1974-12-26. PMID:4424711. |
functional regeneration of 5-hydroxytryptamine nerve terminals in the rat spinal cord following 5, 6-dihydroxytryptamine induced degeneration. |
1974-12-26 |
2023-08-11 |
rat |
| N E Andé. Effect of acute axotomy (spinal cord transection) on the turnover of 5-hydroxytryptamine. Advances in biochemical psychopharmacology. vol 10. 1974-10-02. PMID:4276958. |
effect of acute axotomy (spinal cord transection) on the turnover of 5-hydroxytryptamine. |
1974-10-02 |
2023-08-11 |
Not clear |
| M Bulat, Z Lacković, M Jakupcevic, I Damjano. 5-Hydroxyindoleacetic acid in the lumbar fluid: a specific indicator of spinal cord injury. Science (New York, N.Y.). vol 185. issue 4150. 1974-09-16. PMID:4841583. |
since high concentrations of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid are present in the human lumbosacral cord, it appears that the concentration of 5-hydroxyincdoleacetic acid in the lumbar fluid of animals and man reflects the biochemical changes of 5-hydroxytryptamine in the spinal cord. |
1974-09-16 |
2023-08-11 |
human |
| T Magnusso. Effect of chronic transection on dopamine, noradrenaline and 5-hydroxytryptamine in the rat spinal cord. Naunyn-Schmiedeberg's archives of pharmacology. vol 278. issue 1. 1973-08-09. PMID:4267963. |
effect of chronic transection on dopamine, noradrenaline and 5-hydroxytryptamine in the rat spinal cord. |
1973-08-09 |
2023-08-11 |
rat |
| A Carlsson, M Lindqvist, T Magnusson, C Atac. Effect of acute transection on the synthesis and turnover of 5-HT in the rat spinal cord. Naunyn-Schmiedeberg's archives of pharmacology. vol 277. issue 1. 1973-07-24. PMID:4350468. |
effect of acute transection on the synthesis and turnover of 5-ht in the rat spinal cord. |
1973-07-24 |
2023-08-11 |
rat |
| N E Andén, K Modig. Effects of p-chlorophenylalanine and a monoamine oxidase inhibitor on the 5-hydroxytryptamine in the spinal cord and transection. Journal of neural transmission. vol 33. issue 3. 1973-02-21. PMID:4345169. |
effects of p-chlorophenylalanine and a monoamine oxidase inhibitor on the 5-hydroxytryptamine in the spinal cord and transection. |
1973-02-21 |
2023-08-11 |
Not clear |