Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Santiago Milla-Navarro, Ariadna Diaz-Tahoces, Isabel Ortuño-Lizarán, Eduardo Fernández, Nicolás Cuenca, Francisco Germain, Pedro de la Vill. Visual Disfunction due to the Selective Effect of Glutamate Agonists on Retinal Cells. International journal of molecular sciences. vol 22. issue 12. 2021-07-26. PMID:34200611. |
to globally analyze the effect of glutamate receptor activation in the retina after the intraocular injection of excitotoxic agents, a combination of histological, electrophysiological, and functional tools has been employed to assess the changes in the retinal structure and function. |
2021-07-26 |
2023-08-13 |
Not clear |
Santiago Milla-Navarro, Ariadna Diaz-Tahoces, Isabel Ortuño-Lizarán, Eduardo Fernández, Nicolás Cuenca, Francisco Germain, Pedro de la Vill. Visual Disfunction due to the Selective Effect of Glutamate Agonists on Retinal Cells. International journal of molecular sciences. vol 22. issue 12. 2021-07-26. PMID:34200611. |
the structural and functional injury suffered by the retina suggests the importance of the glutamate receptors expressed by different types of retinal cells. |
2021-07-26 |
2023-08-13 |
Not clear |
Ahmed I Abo-Ahmed, Mahmoud Abdelghaffar Ema. Expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mRNAs in the retina of adult laughing doves (Streptopelia senegalensis): An in situ hybridization study. Acta histochemica. vol 122. issue 6. 2021-06-21. PMID:32778249. |
expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mrnas in the retina of adult laughing doves (streptopelia senegalensis): an in situ hybridization study. |
2021-06-21 |
2023-08-13 |
Not clear |
Ahmed I Abo-Ahmed, Mahmoud Abdelghaffar Ema. Expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mRNAs in the retina of adult laughing doves (Streptopelia senegalensis): An in situ hybridization study. Acta histochemica. vol 122. issue 6. 2021-06-21. PMID:32778249. |
glutamate is the major excitatory neurotransmitter in the vertebrate central nervous system and retina. |
2021-06-21 |
2023-08-13 |
Not clear |
Ahmed I Abo-Ahmed, Mahmoud Abdelghaffar Ema. Expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mRNAs in the retina of adult laughing doves (Streptopelia senegalensis): An in situ hybridization study. Acta histochemica. vol 122. issue 6. 2021-06-21. PMID:32778249. |
the present study was carried out to characterize the expression pattern of vesicular glutamate transporter 2 (vglut2) and 3 (vglut3) and glutamate receptor 1 (glur1) and 2 (glur2) mrnas in the retina of adult laughing dove (streptopelia senegalensis) by rt-pcr and in situ hybridization histochemistry. |
2021-06-21 |
2023-08-13 |
Not clear |
Peter D Lukasiewcz, Gregory W Bligard, James D DeBrech. EAAT5 Glutamate Transporter-Mediated Inhibition in the Vertebrate Retina. Frontiers in cellular neuroscience. vol 15. 2021-05-26. PMID:34025361. |
eaat5 glutamate transporter-mediated inhibition in the vertebrate retina. |
2021-05-26 |
2023-08-13 |
Not clear |
Peter D Lukasiewcz, Gregory W Bligard, James D DeBrech. EAAT5 Glutamate Transporter-Mediated Inhibition in the Vertebrate Retina. Frontiers in cellular neuroscience. vol 15. 2021-05-26. PMID:34025361. |
in the retina, light activates a chloride current, mediated by the glutamate activation of eaat5. |
2021-05-26 |
2023-08-13 |
Not clear |
Chengzhu Yin, Toshiyuki Ishii, Makoto Kaned. Two Types of Cl Transporters Contribute to the Regulation of Intracellular Cl Concentrations in ON- and OFF-type Bipolar Cells in the Mouse Retina. Neuroscience. vol 440. 2021-05-14. PMID:32531472. |
in the retina, on- and off-type bipolar cells are classified by subtype-specific center responses, which are attributed to differences in glutamate receptor subtypes. |
2021-05-14 |
2023-08-13 |
mouse |
Kostadin Dimov Rolev, Xing-Sheng Shu, Ying Yin. Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy. Neuropharmacology. vol 187. 2021-03-23. PMID:33582150. |
these findings have opened up opportunities for therapies, such as inhibition of gsk-3β, glial cell activation, glutamate excitotoxicity and the use of neuroprotective drugs targeting early neurodegenerative processes in the retina and halting the progression of dr before the manifestation of microvascular abnormalities. |
2021-03-23 |
2023-08-13 |
Not clear |
Ping-Ping Zhang, Hui-Hui Yao, An-Hui Zha, Xing-Yue Liu, Ke-Yu Fan, Yue Xu, Hui-Yao Yuan, Lei Li, Lie-Cheng Wan. Cellular localization of the FMRP in rat retina. Bioscience reports. vol 40. issue 6. 2021-03-22. PMID:32452512. |
in the inner retina, gabaergic amacrine cells (acs) labeled by glutamate decarbonylase colocalized with the fmrp. |
2021-03-22 |
2023-08-13 |
rat |
Xiang-Rong Li, Xiaju Cheng, Jia Sun, Yan S Xu, Nannan Chen, Yimei Hao, Chao Huang, Y Eugene Chi. Acetylation-dependent glutamate receptor GluR signalosome formation for STAT3 activation in both transcriptional and metabolism regulation. Cell death discovery. vol 7. issue 1. 2021-01-22. PMID:33446662. |
besides their original regulating roles in the brain, spinal cord, retina, and peripheral nervous system for mediating fast excitatory synaptic transmission, glutamate receptors consisting of metabotropic glutamate receptors (glurs) and ionotropic glutamate receptors (iglurs) have emerged to have a critical role in the biology of cancer initiation, progression, and metastasis. |
2021-01-22 |
2023-08-13 |
Not clear |
Longhui Han, Minglian Zhang, Zanzhang Yang, Ke Diao, Xin Jia, Mingran Li, Genquan Tia. Huoxue-Tongluo-Lishui-Decoction is visual-protective against retinal ischemia-reperfusion injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 125. 2020-12-10. PMID:32070875. |
htld treatment enhanced the expressions of l-glutamate/l-aspartate transporter (glast) and glutamine synthetase (gs), and lower the concentration of free glutamate in retina after reperfusion. |
2020-12-10 |
2023-08-13 |
Not clear |
Estrella Calvo, Santiago Milla-Navarro, Isabel Ortuño-Lizarán, Violeta Gómez-Vicente, Nicolás Cuenca, Pedro De la Villa, Francisco Germai. Deleterious Effect of NMDA Plus Kainate on the Inner Retinal Cells and Ganglion Cell Projection of the Mouse. International journal of molecular sciences. vol 21. issue 5. 2020-11-25. PMID:32106602. |
we conclude that glutamate receptor agonists, nmda and ka, induce a deleterious effect of the inner retina when injected together into the vitreous chamber. |
2020-11-25 |
2023-08-13 |
mouse |
Jovana Bojcevski, Aleksandar Stojic, Dorit B Hoffmann, Sarah K Williams, Andreas Müller, Ricarda Diem, Richard Fairles. Influence of retinal NMDA receptor activity during autoimmune optic neuritis. Journal of neurochemistry. vol 153. issue 6. 2020-11-04. PMID:32031240. |
interestingly, these changes could be mimicked by intravitreal injection of glutamate, and similarly blocked by application of the nmda receptor blocker mk-801, leading us to propose that prior to optic nerve lesion formation, nmda receptor activation within the retina leads to retinal calcium accumulation, actin destabilization within the optic nerve as well as a deterioration of visual acuity during aon. |
2020-11-04 |
2023-08-13 |
rat |
E Palazzo, S Boccella, I Marabese, G Pierretti, F Guida, S Maion. The Cold Case of Metabotropic Glutamate Receptor 6: Unjust Detention in the Retina? Current neuropharmacology. vol 18. issue 2. 2020-11-03. PMID:31573889. |
the cold case of metabotropic glutamate receptor 6: unjust detention in the retina? |
2020-11-03 |
2023-08-13 |
Not clear |
E Palazzo, S Boccella, I Marabese, G Pierretti, F Guida, S Maion. The Cold Case of Metabotropic Glutamate Receptor 6: Unjust Detention in the Retina? Current neuropharmacology. vol 18. issue 2. 2020-11-03. PMID:31573889. |
it is a common opinion that metabotropic glutamate receptor subtype 6 (mglur6) is expressed exclusively in the retina, and in particular in the dendrites of on-bipolar cells. |
2020-11-03 |
2023-08-13 |
Not clear |
Corey M Rountree, Ashwin Raghunathan, John B Troy, Laxman Sagger. Prototype chemical synapse chip for spatially patterned neurotransmitter stimulation of the retina Microsystems & nanoengineering. vol 3. 2020-09-30. PMID:31057878. |
recent studies have demonstrated the feasibility of neurotransmitter stimulation by injecting glutamate, a primary retinal neurotransmitter, into the retina at isolated single sites. |
2020-09-30 |
2023-08-13 |
rat |
Corey M Rountree, Ashwin Raghunathan, John B Troy, Laxman Sagger. Prototype chemical synapse chip for spatially patterned neurotransmitter stimulation of the retina Microsystems & nanoengineering. vol 3. 2020-09-30. PMID:31057878. |
here, we demonstrate spatially patterned multisite stimulation of the retina with glutamate, offering the first experimental evidence for applicability of this strategy for translating visual patterns into afferent neural signals. |
2020-09-30 |
2023-08-13 |
rat |
Guoyao W. Metabolism and Functions of Amino Acids in Sense Organs. Advances in experimental medicine and biology. vol 1265. 2020-09-07. PMID:32761578. |
important metabolites of aas include nitric oxide and polyamines (from arginine), melanin and dopamine (from phenylalanine and tyrosine), and serotonin and melatonin (from tryptophan) in both the eye and the skin; γ-aminobutyrate (from glutamate) in the retina; and urocanic acid and histamine (from histidine) in the skin. |
2020-09-07 |
2023-08-13 |
Not clear |
Deborah L Beaudoin, Mania Kupershtok, Jonathan B Dem. Selective synaptic connections in the retinal pathway for night vision. The Journal of comparative neurology. vol 527. issue 1. 2020-04-16. PMID:28856684. |
here, we investigated functional aii amacrine→rgc synaptic connections in the retina of the guinea pig (cavia porcellus) by recording inhibitory currents from rgcs in the presence of ionotropic glutamate receptor (iglur) antagonists. |
2020-04-16 |
2023-08-13 |
Not clear |