| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Victor J DePiero, Bart G Borghui. Phase advancing is a common property of multiple neuron classes in the mouse retina. eNeuro. 2022-08-22. PMID:35995559. |
to address this, we studied the timing of object motion-evoked responses at multiple signaling stages within the mouse retina using two-photon fluorescence calcium and glutamate imaging, targeted whole-cell electrophysiology, and computational modeling. |
2022-08-22 |
2023-08-14 |
mouse |
| Darya V Telegina, Anna K Antonenko, Anzhela Zh Fursova, Nataliya G Kolosov. The glutamate/GABA system in the retina of male rats: effects of aging, neurodegeneration, and supplementation with melatonin and antioxidant SkQ1. Biogerontology. 2022-08-15. PMID:35969289. |
glutamate and -aminobutyric acid (gaba) are the most abundant amino acids in the retina. |
2022-08-15 |
2023-08-14 |
rat |
| Darya V Telegina, Anna K Antonenko, Anzhela Zh Fursova, Nataliya G Kolosov. The glutamate/GABA system in the retina of male rats: effects of aging, neurodegeneration, and supplementation with melatonin and antioxidant SkQ1. Biogerontology. 2022-08-15. PMID:35969289. |
at a late stage of amd-like retinopathy in oxys rats (18 months), there was significant upregulation of glutaminase and downregulation of glutamine synthetase, possibly indicating an increasing level of glutamate in the retina. |
2022-08-15 |
2023-08-14 |
rat |
| Shirui Dai, Chao Wang, Lemeng Feng, Cheng Zhang, Wulong Zhang, Ye He, Xuezhi Zhou, Xiaobo Xia, Baihua Chen, Weitao Son. Protective activity of tert-butylhydroquinone against oxidative stress and apoptosis induced by glutamate agonizts in R28 cells and mice retina. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-02. PMID:35653886. |
protective activity of tert-butylhydroquinone against oxidative stress and apoptosis induced by glutamate agonizts in r28 cells and mice retina. |
2022-06-02 |
2023-08-14 |
mouse |
| Isabella Boccuni, Richard Fairles. Retinal Glutamate Neurotransmission: From Physiology to Pathophysiological Mechanisms of Retinal Ganglion Cell Degeneration. Life (Basel, Switzerland). vol 12. issue 5. 2022-05-28. PMID:35629305. |
within the retina, glutamate excitotoxicity can impair visual transmission by initiating degeneration of neuronal populations, including retinal ganglion cells (rgcs). |
2022-05-28 |
2023-08-13 |
Not clear |
| Tee Hann Yih, Afiqq Aiman Abd Ghapor, Renu Agarwal, Norhafiza Razali, Igor Iezhitsa, Nafeeza Mohd Ismai. Effect of trans-resveratrol on glutamate clearance and visual behaviour in rats with glutamate induced retinal injury. Experimental eye research. 2022-05-16. PMID:35577069. |
trans-resveratrol is known for its neuroprotective effects; however, its effects on the expression of glutamate transporters and glutamate clearance in retina remain unclear. |
2022-05-16 |
2023-08-13 |
rat |
| Fu-Sheng Tang, He-Lan Yuan, Jun-Bin Liu, Gong Zhang, Si-Yun Chen, Jiang-Bin K. Glutamate transporters EAAT2 and EAAT5 differentially shape synaptic transmission from rod bipolar cell terminals. eNeuro. 2022-05-06. PMID:35523583. |
excitatory amino acid transporters (eaats) control visual signal transmission in the retina by rapidly removing glutamate released from photoreceptors and bipolar cells. |
2022-05-06 |
2023-08-13 |
mouse |
| Irene O Lee, David H Skuse, Paul A Constable, Fernando Marmolejo-Ramos, Ludvig R Olsen, Dorothy A Thompso. The electroretinogram b-wave amplitude: a differential physiological measure for Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder. Journal of neurodevelopmental disorders. vol 14. issue 1. 2022-05-06. PMID:35524181. |
both are potentially associated with abnormal glutamate and gaba neurotransmission, which can be modelled by measuring the synaptic activity in the retina with an electroretinogram (erg). |
2022-05-06 |
2023-08-13 |
Not clear |
| A Lee, S Klinkradt, P A McCombe, D V Po. Cloning of a new form of EAAT2/GLT-1 from human and rodent brains. Neuroscience letters. 2022-04-19. PMID:35439550. |
the splice variant is abundantly expressed in the brain, spinal cord, retina, liver and testis; it is a functional glutamate transporter; therefore, we conclude that it will likely have a functional role in glutamate homeostasis in the rodent and human nervous system, during development, adulthood, and plausibly in pathological states. |
2022-04-19 |
2023-08-13 |
human |
| Lisa Klotz-Weigand, Ralf En. Metabotropic Glutamate Receptors at Ribbon Synapses in the Retina and Cochlea. Cells. vol 11. issue 7. 2022-04-12. PMID:35406660. |
metabotropic glutamate receptors at ribbon synapses in the retina and cochlea. |
2022-04-12 |
2023-08-13 |
Not clear |
| Jana Gehlen, Christoph Aretzweiler, Anja Mataruga, Christoph Fahlke, Frank Mülle. Excitatory Amino Acid Transporter EAAT5 Improves Temporal Resolution in the Retina. eNeuro. vol 8. issue 6. 2021-12-11. PMID:34772693. |
in the retina, eaat1 and eaat2 are considered the major glutamate transporters. |
2021-12-11 |
2023-08-13 |
mouse |
| Kumar Abhiram Jha, Jordy Gentry, Nobel A Del Mar, Anton Reiner, Nicolas Sohl, Rajashekhar Gangaraj. Adipose Tissue-Derived Mesenchymal Stem Cell Concentrated Conditioned Medium Alters the Expression Pattern of Glutamate Regulatory Proteins and Aquaporin-4 in the Retina after Mild Traumatic Brain Injury. Journal of neurotrauma. vol 38. issue 12. 2021-11-18. PMID:33183134. |
adipose tissue-derived mesenchymal stem cell concentrated conditioned medium alters the expression pattern of glutamate regulatory proteins and aquaporin-4 in the retina after mild traumatic brain injury. |
2021-11-18 |
2023-08-13 |
mouse |
| Erika D Eggers, Teresia A Carreo. The effects of early diabetes on inner retinal neurons. Visual neuroscience. vol 37. 2021-10-28. PMID:32933604. |
mechanistic in vitro neuronal studies have suggested that these inner retinal changes are due to decreased inhibition in the retina, potentially due to decreased gamma aminobutyric acid (gaba) release, increased glutamate release, and increased excitation of retinal ganglion cells. |
2021-10-28 |
2023-08-13 |
human |
| Anuradha Dhingra, Noga Vard. "mGlu Receptors in the Retina" - WIREs Membrane Transport and Signaling. Wiley interdisciplinary reviews. Membrane transport and signaling. vol 1. issue 5. 2021-10-21. PMID:24003403. |
glutamate, a key neurotransmitter in the vertebrate retina, acts via ionotropic and metabotropic receptors. |
2021-10-21 |
2023-08-12 |
Not clear |
| Anuradha Dhingra, Noga Vard. "mGlu Receptors in the Retina" - WIREs Membrane Transport and Signaling. Wiley interdisciplinary reviews. Membrane transport and signaling. vol 1. issue 5. 2021-10-21. PMID:24003403. |
retina expresses mrna for all metabotropic glutamate receptors and proteins for all but mglur3. |
2021-10-21 |
2023-08-12 |
Not clear |
| Wolfrat Bachert, Lisa Klotz, Heinrich Sticht, Ralf En. Homodimerization of a proximal region within the C-terminus of the orphan G-protein coupled receptor GPR179. Neurochemistry international. vol 149. 2021-10-06. PMID:34333057. |
the orphan g-protein coupled receptor gpr179 is a central component of a 1 megadalton large signalling complex in the on-pathway of the mammalian retina that assembles multiple proteins, including the metabotropic glutamate receptor mglur6. |
2021-10-06 |
2023-08-13 |
Not clear |
| Pablo Beltrán-Matas, Espen Hartveit, Margaret L Veruk. Different glutamate sources and endogenous co-agonists activate extrasynaptic NMDA receptors on amacrine cells of the rod pathway microcircuit. The European journal of neuroscience. vol 54. issue 2. 2021-08-13. PMID:34048091. |
the nmda receptors (nmdars) expressed by aii and a17 amacrine cells, the two main inhibitory interneurons of the rod pathway microcircuit in the mammalian retina, are exclusively extrasynaptic, activated by ambient levels of glutamate, and molecularly distinct, with aii and a17 amacrines expressing glun2b- and glun2a-containing receptors, respectively. |
2021-08-13 |
2023-08-13 |
rat |
| Pablo Beltrán-Matas, Espen Hartveit, Margaret L Veruk. Different glutamate sources and endogenous co-agonists activate extrasynaptic NMDA receptors on amacrine cells of the rod pathway microcircuit. The European journal of neuroscience. vol 54. issue 2. 2021-08-13. PMID:34048091. |
pre-incubation of retina with bafilomycin a1 (an inhibitor of neurotransmitter uptake into synaptic vesicles) abolished nmdar-mediated noise in aii, but not a17 amacrines, suggesting a vesicular source of glutamate activates aii nmdars, whereas a non-vesicular source activates a17 nmdars. |
2021-08-13 |
2023-08-13 |
rat |
| Pablo Beltrán-Matas, Espen Hartveit, Margaret L Veruk. Different glutamate sources and endogenous co-agonists activate extrasynaptic NMDA receptors on amacrine cells of the rod pathway microcircuit. The European journal of neuroscience. vol 54. issue 2. 2021-08-13. PMID:34048091. |
pre-incubation of retina with l-methionine sulfoximine (an inhibitor of glutamine synthetase) also abolished nmdar-mediated noise in aii, but not a17 amacrines, suggesting a neuronal source of glutamate activates aii nmdars, whereas a glial source activates a17 nmdars. |
2021-08-13 |
2023-08-13 |
rat |
| Xiaoyu Li, Jiajun Lv, Jiazhi Li, Xiang Re. Kir4.1 may represent a novel therapeutic target for diabetic retinopathy (Review). Experimental and therapeutic medicine. vol 22. issue 3. 2021-08-11. PMID:34373707. |
the imbalance of the retinal microenvironment and destruction of the blood-retinal barrier have a significant role in the progression of dr. inward rectifying potassium channel 4.1 (kir4.1) is located on müller cells and is closely related to potassium homeostasis, water balance and glutamate clearance in the whole retina. |
2021-08-11 |
2023-08-13 |
Not clear |