| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ernesto Solis, Anum Afzal, Eugene A Kiyatki. Changes in brain oxygen and glucose induced by oxycodone: Relationships with brain temperature and peripheral vascular tone. Neuropharmacology. vol 133. 2018-11-05. PMID:29476778. |
high-speed amperometry was used to assess how oxycodone affects oxygen and glucose levels in the nucleus accumbens (nac). |
2018-11-05 |
2023-08-13 |
rat |
| Juhwan Kim, Sueun Lee, Sohi Kang, Tae-Il Jeon, Man-Jong Kang, Tae-Hoon Lee, Yong Sik Kim, Key-Sun Kim, Heh-In Im, Changjong Moo. Regulator of G-Protein Signaling 4 (RGS4) Controls Morphine Reward by Glutamate Receptor Activation in the Nucleus Accumbens of Mouse Brain. Molecules and cells. vol 41. issue 5. 2018-10-30. PMID:29754475. |
a previous study showed that regulator of g-protein signaling 4 (rgs4) may be implicated in opiate action in the nucleus accumbens (nac). |
2018-10-30 |
2023-08-13 |
mouse |
| Tong Zhang, Satoshi Deyama, Masaki Domoto, Shintaro Wada, Junko Yanagida, Hitoki Sasase, Eiichi Hinoi, Naoya Nishitani, Kazuki Nagayasu, Shuji Kaneko, Katsuyuki Kaned. Activation of GABAergic Neurons in the Nucleus Accumbens Mediates the Expression of Cocaine-Associated Memory. Biological & pharmaceutical bulletin. vol 41. issue 7. 2018-10-24. PMID:29962403. |
here, we investigated the possible contribution of γ-aminobutyrate (gaba)ergic neurons in the nucleus accumbens (nac), a key brain region associated with the rewarding and reinforcing effects of cocaine, to the expression of cocaine-associated memory using the conditioned place preference (cpp) paradigm combined with designer receptors exclusively activated by designer drugs (dreadd) technology. |
2018-10-24 |
2023-08-13 |
mouse |
| Biao Yan, Zhaoyang Hu, Wenqing Yao, Qiumin Le, Bo Xu, Xing Liu, Lan M. MiR-218 targets MeCP2 and inhibits heroin seeking behavior. Scientific reports. vol 7. 2018-10-22. PMID:28074855. |
microarray screening was also carried out to identify mirnas responding to chronic heroin administration in the nucleus accumbens (nac). |
2018-10-22 |
2023-08-13 |
Not clear |
| Chuchu Qi, Baolin Guo, Keke Ren, Han Yao, Mengmeng Wang, Tangna Sun, Guohong Cai, Haiying Liu, Rui Li, Ceng Luo, Wenting Wang, Shengxi W. Chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens. Molecular pain. vol 14. 2018-10-22. PMID:29770746. |
reward system has been proved to be important to nociceptive behavior, and the nucleus accumbens (nac) is a key node in reward circuitry. |
2018-10-22 |
2023-08-13 |
mouse |
| Baijuan Xia, Yixin Li, Rongrong Li, Dan Yin, Xingqiang Chen, Jie Li, Wenmei Lian. Effect of Sirtuin-1 on Synaptic Plasticity in Nucleus Accumbens in a Rat Model of Heroin Addiction. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-16. PMID:29870523. |
this study investigated the relationship between synaptic plasticity and changes in addictive behavior and examined the expression of synaptic plasticity-associated proteins and genes in the nucleus accumbens (nac) region in different rat models. |
2018-10-16 |
2023-08-13 |
rat |
| Mrunal Rane, Rohit Manchand. Effects of location and extent of spine clustering on synaptic integration in striatal medium spiny neurons-a computational study. Medical & biological engineering & computing. vol 56. issue 7. 2018-10-15. PMID:29209962. |
the nucleus accumbens (nac) is known widely for its role in the reward circuit, which is dysregulated in a number of psychological disorders. |
2018-10-15 |
2023-08-13 |
Not clear |
| Jia Liu, Karen Dietz, Georgia E Hodes, Scott J Russo, Patrizia Casacci. Widespread transcriptional alternations in oligodendrocytes in the adult mouse brain following chronic stress. Developmental neurobiology. vol 78. issue 2. 2018-10-09. PMID:28884925. |
in concert with these behavioral responses, transcriptional analysis of pfc, and nucleus accumbens (nac)-a brain region critical for reward response-revealed downregulation of transcripts encoding for myelin genes and oligodendrocyte-specific genes. |
2018-10-09 |
2023-08-13 |
mouse |
| Lisa Ulenius, Louise Adermark, Bo Söderpalm, Mia Ericso. Ethanol-Induced Taurine Elevation in the Rat Dorsal Striatum. Advances in experimental medicine and biology. vol 975 Pt 1. 2018-10-02. PMID:28849453. |
in the search for the primary mechanism underlying the dopamine elevating properties of ethanol we have established that raised levels of taurine in the nucleus accumbens (nac) is pivotal. |
2018-10-02 |
2023-08-13 |
rat |
| André O White, Enikö A Kramár, Alberto J López, Janine L Kwapis, John Doan, David Saldana, M Felicia Davatolhagh, Yasaman Alaghband, Mathew Blurton-Jones, Dina P Matheos, Marcelo A Woo. BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens. Nature communications. vol 7. 2018-09-24. PMID:27226355. |
similar to the memory deficits, theta-induced long-term potentiation (theta-ltp) in the nucleus accumbens (nac) is significantly impaired in slices taken from baf53b transgenic mice but not heterozygous mice. |
2018-09-24 |
2023-08-13 |
mouse |
| Ken T Wakabayashi, Michael J Bruno, Caroline E Bass, Jinwoo Par. Application of fast-scan cyclic voltammetry for the in vivo characterization of optically evoked dopamine in the olfactory tubercle of the rat brain. The Analyst. vol 141. issue 12. 2018-09-19. PMID:27063845. |
the results were compared with da regulation in the nucleus accumbens (nac), a structure located adjacent to the ot and which also receives dense da innervation from the vta. |
2018-09-19 |
2023-08-13 |
rat |
| Xue-Jiao Gao, Kai Yuan, Lu Cao, Wei Yan, Yi-Xiao Luo, Min Jian, Jian-Feng Liu, Qin Fang, Ji-Shi Wang, Ying Han, Jie Shi, Lin L. AMPK signaling in the nucleus accumbens core mediates cue-induced reinstatement of cocaine seeking. Scientific reports. vol 7. issue 1. 2018-09-18. PMID:28432301. |
here, we investigated the role of ampk activity in the nucleus accumbens (nac) in relapse to cocaine seeking. |
2018-09-18 |
2023-08-13 |
Not clear |
| Kyle A Windisch, Cristine L Czachowsk. Effects of group II metabotropic glutamate receptor modulation on ethanol- and sucrose-seeking and consumption in the rat. Alcohol (Fayetteville, N.Y.). vol 66. 2018-09-17. PMID:29220747. |
a microinjection study was then performed to examine the role of nucleus accumbens (nac) core mglur2/3 on ethanol-seeking. |
2018-09-17 |
2023-08-13 |
rat |
| Peter J Vollbrecht, Kathryn M Nesbitt, Omar S Mabrouk, Aaron M Chadderdon, Emily M Jutkiewicz, Robert T Kennedy, Carrie R Ferrari. Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats. Behavioural brain research. vol 346. 2018-09-11. PMID:29129597. |
differences in the function of brain reward circuits, including in the nucleus accumbens (nac), have been shown in obesity-prone vs. obesity-resistant populations, leading many researchers to explore the role of striatal dopamine in obesity. |
2018-09-11 |
2023-08-13 |
rat |
| Byeong Jun Kang, Shelly Sooyun Song, Lei Wen, Ki-Pyo Hong, George J Augustine, Ja-Hyun Bai. Effect of optogenetic manipulation of accumbal medium spiny neurons expressing dopamine D2 receptors in cocaine-induced behavioral sensitization. The European journal of neuroscience. vol 46. issue 4. 2018-09-06. PMID:28708260. |
dopamine d1 receptors (d1r) or d2 receptors (d2r) expressed in the medium spiny neurons (msns) of the nucleus accumbens (nac) play critical roles in the control of addictive behaviors. |
2018-09-06 |
2023-08-13 |
mouse |
| Zahra Farzinpour, Zahra Mousavi, Saeideh Karimi-Haghighi, Abbas Haghparas. Antagonism of the D1- and D2-like dopamine receptors in the nucleus accumbens attenuates forced swim stress- and morphine priming-induced reinstatement of extinguished rats. Behavioural brain research. vol 341. 2018-09-04. PMID:29246771. |
dopaminergic pathways from the ventral tegmental area (vta) to the nucleus accumbens (nac) play a critical role in reward-related phenomena as well as in the reinstatement of drug-seeking behavior. |
2018-09-04 |
2023-08-13 |
rat |
| Amanda L Maciel, Helena M Abelaira, Airam B de Moura, Thays G de Souza, Thayse Rosa, Danyela Matos, Talita Tuon, Leandro Garbossa, Ana Paula Strassi, Maria Eduarda Fileti, Mariana P Goldim, Khiany Mathias, Fabricia Petronilho, João Quevedo, Gislaine Z Réu. Acute treatment with ketamine and chronic treatment with minocycline exert antidepressant-like effects and antioxidant properties in rats subjected different stressful events. Brain research bulletin. vol 137. 2018-08-31. PMID:29253605. |
after treatment, the animals were submitted to the forced swimming test and then analyzed oxidative stress parameters in the prefrontal cortex (pfc), hippocampus, amygdala and nucleus accumbens (nac). |
2018-08-31 |
2023-08-13 |
rat |
| Marjan Sahafzadeh, Saeideh Karimi-Haghighi, Zahra Mousavi, Abbas Haghparas. Role of the orexin receptors within the nucleus accumbens in the drug priming-induced reinstatement of morphine seeking in the food deprived rats. Brain research bulletin. vol 137. 2018-08-31. PMID:29258865. |
the nucleus accumbens (nac) has an important role in the reward system and receives orexinergic projections of the lateral hypothalamus. |
2018-08-31 |
2023-08-13 |
rat |
| Ronny N Gentry, Brian Lee, Matthew R Roesc. Phasic dopamine release in the rat nucleus accumbens predicts approach and avoidance performance. Nature communications. vol 7. 2018-08-27. PMID:27786172. |
using a combined approach-avoidance task, we measured phasic da release in the nucleus accumbens (nac) of rats during presentation of cues that predicted reward, punishment or neutral outcomes and investigated individual differences based on avoidance performance. |
2018-08-27 |
2023-08-13 |
rat |
| Carina Soares-Cunha, Barbara Coimbra, Ana David-Pereira, Sonia Borges, Luisa Pinto, Patricio Costa, Nuno Sousa, Ana J Rodrigue. Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation. Nature communications. vol 7. 2018-08-22. PMID:27337658. |
here we demonstrate that the pattern of activation of d1 and d2 neurons in the nucleus accumbens (nac) predicts motivational drive, and that optogenetic activation of either neuronal population enhances motivation in mice. |
2018-08-22 |
2023-08-13 |
mouse |