| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaili Du, Qianwen Shi, Xiuya Zhou, Lifei Zhang, Hongliang Su, Chao Zhang, Zhiwen Wei, Ting Liu, Li Wang, Xiaohui Wang, Bin Cong, Keming Yu. Melatonin attenuates fentanyl - induced behavioral sensitization and circadian rhythm disorders in mice. Physiology & behavior. 2024-03-16. PMID:38492912. |
the accompanying changes in the expression of brain and muscle arnt-like (bmal1), tyrosine hydroxylase (th), and monoamine oxidase a (mao-a) in relevant brain regions including the suprachiasmatic nucleus (scn), nucleus accumbens (nac), prefrontal cortex (pfc), and hippocampus (hip) were investigated by western blot assays to dissect the mechanism by which melatonin modulates fentanyl - induced behavioral sensitization and circadian rhythm disorders. |
2024-03-16 |
2024-03-19 |
mouse |
| Yujing Wang, Fan Duan, Junda Li, Xiangyu Li, Lingling Xia, Wei Zhao, Ze Wang, Xun Song, Juan Chen, Jingjing Wang, Yue Wang, Jing Zhang, Xiaochu Zhang, Dongliang Jia. Involvement of nucleus accumbens SERCA2b in methamphetamine-induced conditioned place preference. Addiction biology. vol 29. issue 3. 2024-03-15. PMID:38488467. |
methamphetamine (meth) is a highly addictive psycho-stimulant that induces addictive behaviour by stimulating increased dopamine release in the nucleus accumbens (nac). |
2024-03-15 |
2024-03-17 |
mouse |
| Sara Ouaidat, Inês M Amaral, Diogo G Monteiro, Hayat Harati, Alex Hofer, Rana El Rawa. Orexins/Hypocretins: Gatekeepers of Social Interaction and Motivation. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473854. |
furthermore, we refer to published research to investigate the stage at which orexins affect social interaction and we highlight the nucleus accumbens (nac) shell's role in social interaction and other rewarding behaviors. |
2024-03-13 |
2024-03-15 |
Not clear |
| Sofia Beas, Isbah Khan, Claire Gao, Gabriel Loewinger, Emma Macdonald, Alison Bashford, Shakira Rodriguez-Gonzalez, Francisco Pereira, Mario A Penz. Dissociable encoding of motivated behavior by parallel thalamo-striatal projections. Current biology : CB. 2024-03-08. PMID:38458192. |
the paraventricular nucleus of the thalamus (pvt) is a midline thalamic nucleus that shapes motivated behaviors via its projections to the nucleus accumbens (nac) |
2024-03-08 |
2024-03-11 |
Not clear |
| Shen Lin, Cui-Ying Fan, Hao-Ran Wang, Xiao-Fan Li, Jia-Li Zeng, Pei-Xuan Lan, Hui-Xian Li, Bin Zhang, Chun Hu, Junyu Xu, Jian-Hong Lu. Frontostriatal circuit dysfunction leads to cognitive inflexibility in neuroligin-3 R451C knockin mice. Molecular psychiatry. 2024-03-08. PMID:38459194. |
single-unit recording of medium spiny neuron (msn) activity in the nucleus accumbens (nac) revealed altered encoding of decision-related cue and impaired updating of choice anticipation in ki mice. |
2024-03-08 |
2024-03-11 |
mouse |
| Jian Ye, Shuang-Qi Gao, Zi-Cun Liu, Xi Chen, Jin-Gang He, Zhuang-Li H. The HMGB1-RAGE axis in nucleus accumbens facilitates cocaine-induced conditioned place preference via modulating microglial activation. Brain and behavior. vol 14. issue 3. 2024-03-07. PMID:38450910. |
cocaine exposure also induces a release of high mobility group box-1 (hmgb1) from neurons into the extracellular space in the nucleus accumbens (nac). |
2024-03-07 |
2024-03-09 |
Not clear |
| Julia M Kirkland, Erin L Edgar, Ishan Patel, Paul Feustel, Sophie Belin, Ashley M Kope. Synaptic pruning during adolescence shapes adult social behavior in both males and females. Developmental psychobiology. vol 66. issue 3. 2024-03-04. PMID:38433422. |
the nucleus accumbens (nac) is an intermediate reward relay center that develops during adolescence and mediates both social behaviors and dopaminergic signaling. |
2024-03-04 |
2024-03-06 |
human |
| Ioannis Bakoyiannis, Eva Gunnel Ducourneau, Mateo N'diaye, Alice Fermigier, Celine Ducroix-Crepy, Clementine Bosch-Bouju, Etienne Coutureau, Pierre Trifilieff, Guillaume Ferreir. Obesogenic diet induces circuit-specific memory deficits in mice. eLife. vol 13. 2024-03-04. PMID:38436653. |
here, we used an intersectional viral approach in hfd-fed male mice to chemogenetically inactivate specific vhpc efferent pathways to nucleus accumbens (nac) or medial prefrontal cortex (mpfc) during memory tasks. |
2024-03-04 |
2024-03-06 |
mouse |
| Kangsheng Zhu, Siruan Chen, Xia Qin, Wanjun Bai, Jie Hao, Xiaolei Xu, Han Guo, Hui Bai, Zuxiao Yang, Sheng Wang, Zongmao Zhao, Tengfei Ji, Dezhi Kong, Wei Zhan. Exploring the therapeutic potential of cannabidiol for sleep deprivation-induced hyperalgesia. Neuropharmacology. 2024-03-01. PMID:38428482. |
the nucleus accumbens (nac) plays a crucial role in the modulation of pain and sleep, with its activity regulated by two distinct types of medium spiny neurons (msns) expressing dopamine 1 or dopamine 2 (d1-or d2) receptors (referred to as d1-msns and d2-msns, respectively). |
2024-03-01 |
2024-03-04 |
mouse |
| Yiqiong Liu, Ying Wang, Zhengdong Zhao, Guoguang Xie, Chao Zhang, Renchao Chen, Yi Zhan. A molecularly defined NAcSh D1 subtype controls feeding and energy homeostasis. bioRxiv : the preprint server for biology. 2024-02-29. PMID:36909586. |
in addition to hypothalamus neuronal circuits, the nucleus accumbens (nac) also plays an important role in controlling appetite and satiety in responses to changing external stimuli. |
2024-02-29 |
2024-03-02 |
Not clear |
| Qingyao Kong, Xiaoyang Wu, Ming X. A Genetically Modified Skin Graft for Treating Alcohol Use Disorder and/or Polysubstance Abuse With Cocaine. Advances in drug and alcohol research. vol 1. 2024-02-23. PMID:38390403. |
we have developed and used a skin stem cell-based gene delivery platform and found that production of the glucagon-like peptide-1 (glp1) from the grafted genetically modified skin reduced development and reinstatement of alcohol-induced drug-taking and seeking, voluntary oral alcohol consumption and alcohol-induced increase in dopamine (da) levels in the nucleus accumbens (nac). |
2024-02-23 |
2024-02-25 |
human |
| Yuka Kusui, Naotaka Izuo, Reika Tokuhara, Takashi Asano, Atsumi Nitt. Neuronal activation of nucleus accumbens by local methamphetamine administration induces cognitive impairment through microglial inflammation in mice. Journal of pharmacological sciences. vol 154. issue 3. 2024-02-23. PMID:38395513. |
meth causes neuronal hyperactivation in the nucleus accumbens (nac) by aberrantly releasing dopamine, which triggers dependence. |
2024-02-23 |
2024-02-26 |
mouse |
| Hongyu Yang, Xiuning Zhang, Minglong Zhang, Yun Lu, Bing Xie, Shaoguang Sun, Hailei Yu, Bin Cong, Yixiao Luo, Chunling Ma, Di We. Roles of lncLingo2 and its derived miR-876-5p in the acquisition of opioid reinforcement. Addiction biology. vol 29. issue 2. 2024-02-21. PMID:38380802. |
in this study, we characterized lncrna transcriptome profiles in the nucleus accumbens (nac) of mice exhibiting morphine-conditioned place preference (cpp) and explored the prospective roles of novel differentially expressed lncrna, lnclingo2 and its derived mir-876-5p in the acquisition of opioids-associated behaviours. |
2024-02-21 |
2024-02-23 |
mouse |
| C Medina-Saldivar, G V E Pardo, L F Pacheco-Otalor. Effect of MCH1, a fatty-acid amide hydrolase inhibitor, on the depressive-like behavior and gene expression of endocannabinoid and dopaminergic-signaling system in the mouse nucleus accumbens. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 57. 2024-02-21. PMID:38381881. |
this inhibition can modulate endocannabinoid and dopamine signaling in the nucleus accumbens (nac), potentially having an antidepressant-like effect. |
2024-02-21 |
2024-02-24 |
mouse |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Conner W Wallace, Katherine M Holleran, Clare Y Slinkard, Samuel W Centanni, Sara R Jone. Kappa Opioid Receptors Negatively Regulate Real Time Spontaneous Dopamine Signals by Reducing Release and Increasing Uptake. bioRxiv : the preprint server for biology. 2024-02-19. PMID:38370660. |
to explore kor influences on real-time da fluctuations, we used the photosensor dlight1.2 with fiber photometry in the nucleus accumbens (nac) core of freely moving male and female c57bl/6 mice. |
2024-02-19 |
2024-02-21 |
mouse |
| Nan Song, Zhenhong Liu, Yan Gao, Shanshan Lu, Shenglian Yang, Chao Yua. NAc-DBS corrects depression-like behaviors in CUMS mouse model via disinhibition of DA neurons in the VTA. Molecular psychiatry. 2024-02-16. PMID:38361128. |
mdd can be associated with abnormalities in the reward-system-dopaminergic mesolimbic pathway, in which the nucleus accumbens (nac) and ventral tegmental area (vta) play major roles. |
2024-02-16 |
2024-02-18 |
mouse |
| Julien Castel, Guangping Li, Oriane Onimus, Emma Leishman, Patrice D Cani, Heather Bradshaw, Ken Mackie, Amandine Everard, Serge Luquet, Giuseppe Gangaross. NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis. Molecular psychiatry. 2024-02-16. PMID:38361126. |
reward-dependent behaviors depend on dopamine (da) transmission between the ventral tegmental area (vta) and the nucleus accumbens (nac), which conveys reward-values and scales reinforced behaviors. |
2024-02-16 |
2024-02-18 |
Not clear |
| Xiaoxi Zhao, Aqian Hu, Yanyan Wang, Tianshu Zhao, Xiaojun Xian. Paraventricular thalamus to nucleus accumbens circuit activation decreases long-term relapse of alcohol-seeking behaviour in male mice. Pharmacology, biochemistry, and behavior. 2024-02-15. PMID:38360104. |
the pathway from the anterior paraventricular thalamus (pvt) to the shell of the nucleus accumbens (nac) has been reported as an essential regulatory pathway for processing aversion and is also closely associated with substance addiction. |
2024-02-15 |
2024-02-18 |
mouse |
| Bo-Han He, Ya-Hui Yang, Bo-Wen Hsiao, Wan-Ting Lin, Yi-Fang Chuang, Shih-Yun Chen, Fu-Chin Li. Foxp2 is Required for Nucleus Accumbens-mediated Multifaceted Limbic Function. Neuroscience. 2024-02-14. PMID:38354901. |
although foxp2 has been well studied in the dorsal striatum, its function in the nucleus accumbens (nac) of the ventral striatum remains elusive. |
2024-02-14 |
2024-02-17 |
mouse |