| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erkki Tupala, Håkan Hall, Kim Bergström, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jukka Hiltunen, Jari Tiihone. Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687640. |
we studied the effect of age on dat in caudate (nc), putamen (pu), and nucleus accumbens (nac) of eight type 1 and 2 alcoholics and 10 healthy controls by using [(125)i]pe2i as a radioligand for postmortem human whole hemisphere autoradiography. |
2003-07-25 |
2023-08-12 |
human |
| Jacqueline D Van Hoomissen, Heather O Chambliss, Philip V Holmes, Rod K Dishma. Effects of chronic exercise and imipramine on mRNA for BDNF after olfactory bulbectomy in rat. Brain research. vol 974. issue 1-2. 2003-07-22. PMID:12742641. |
we examined the effects of chronic activity wheel running and antidepressant treatment on brain-derived neurotrophic factor (bdnf) messenger rna (mrna) in multiple brain regions-hippocampal formation (hf), ventral tegmental area/substantia nigra (vta/sn), nucleus accumbens (nac), and piriform cortex (pfx)-after bilateral olfactory bulbectomy (obx). |
2003-07-22 |
2023-08-12 |
rat |
| Stefan D Schlussman, Yong Zhang, Vadim Yuferov, K Steven LaForge, Ann Ho, Mary Jeanne Kree. Acute 'binge' cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice. Brain research. vol 974. issue 1-2. 2003-07-22. PMID:12742644. |
preprodynorphin mrna was measured in the nucleus accumbens (nac) and caudate putamen (cpu) after 3-day 'binge' pattern cocaine administration in c57bl/6j and 129/j mice, strains which differ in behavior and in dopamine increases in the cpu after 'binge' cocaine. |
2003-07-22 |
2023-08-12 |
mouse |
| Margery C Beinfel. What we know and what we need to know about the role of endogenous CCK in psychostimulant sensitization. Life sciences. vol 73. issue 6. 2003-07-17. PMID:12801586. |
cck microdialysis studies in the nucleus accumbens (nac) have demonstrated that extracellular cck is increased in the nac by psychostimulants, providing neurochemical evidence that cck could be involved in the behavioral response to psychostimulants. |
2003-07-17 |
2023-08-12 |
rat |
| Thomas M Loonam, Pierre A H Noailles, Jing Yu, Judy P Q Zhu, Jesus A Angul. Substance P and cholecystokinin regulate neurochemical responses to cocaine and methamphetamine in the striatum. Life sciences. vol 73. issue 6. 2003-07-17. PMID:12801594. |
the mechanism of action of drugs of abuse like cocaine and amphetamines has been studied extensively in the dopamine terminal field areas of the caudate-putamen (cpu) and the nucleus accumbens (nac) of the rodent brain. |
2003-07-17 |
2023-08-12 |
mouse |
| Susan R Sesack, David B Car. Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiology & behavior. vol 77. issue 4-5. 2003-07-11. PMID:12526992. |
dopamine (da) neurons in the substantia nigra (sn) and ventral tegmental area (vta) form several projection systems with diverse functions, such as motor planning through the striatum, reward seeking via the nucleus accumbens (nac), and cognitive control through the prefrontal cortex (pfc). |
2003-07-11 |
2023-08-12 |
Not clear |
| Toshihide Kuroki, Herbert Y Meltzer, Junji Ichikaw. 5-HT 2A receptor stimulation by DOI, a 5-HT 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain research. vol 972. issue 1-2. 2003-07-11. PMID:12711095. |
(+/-)-([1-(2,5-dimethoxy-4-iodophenyl)-aminopropane]-hydrochloride) (doi) (2.5 mg/kg), a 5-ht(2a/2c) agonist, significantly potentiated d-amphetamine (amph) (1 mg/kg)-induced dopamine (da) release in rat medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2003-07-11 |
2023-08-12 |
rat |
| M-C Peakman, C Colby, L I Perrotti, P Tekumalla, T Carle, P Ulery, J Chao, C Duman, C Steffen, L Monteggia, M R Allen, J L Stock, R S Duman, J D McNeish, M Barrot, D W Self, E J Nestler, E Schaeffe. Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain research. vol 970. issue 1-2. 2003-07-08. PMID:12706249. |
administration of cocaine induces the fos family of transcription factors in the striatum, including the nucleus accumbens (nac), a brain region important for the rewarding effects of addictive drugs. |
2003-07-08 |
2023-08-12 |
mouse |
| Gregory O Hjelmstad, Howard L Field. Kappa opioid receptor activation in the nucleus accumbens inhibits glutamate and GABA release through different mechanisms. Journal of neurophysiology. vol 89. issue 5. 2003-07-02. PMID:12740400. |
through their actions in the nucleus accumbens (nac), kappa opioid (kop) receptors and their endogenous ligand, dynorphin, modify behaviors associated with the administration of drugs of abuse and are regulated by exposure to such drugs. |
2003-07-02 |
2023-08-12 |
Not clear |
| Takatoshi Hikida, Yasuji Kitabatake, Ira Pastan, Shigetada Nakanish. Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 10. 2003-07-01. PMID:12721372. |
cocaine and morphine elevate dopamine levels in the nucleus accumbens (nac), and the overwhelming actions of dopamine are implicated in reinforcement and addiction of abusive drugs. |
2003-07-01 |
2023-08-12 |
Not clear |
| C W Stevenson, A Gratto. Basolateral amygdala modulation of the nucleus accumbens dopamine response to stress: role of the medial prefrontal cortex. The European journal of neuroscience. vol 17. issue 6. 2003-06-27. PMID:12670317. |
the basolateral amygdala (bla) is involved in modulating affective responses to stress and, along with the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), receives a stress-responsive dopamine (da) projection from the ventral tegmental area. |
2003-06-27 |
2023-08-12 |
rat |
| C P Müller, R J Carey, J B Salloum, J P Husto. Serotonin1A-receptor agonism attenuates the cocaine-induced increase in serotonin levels in the hippocampus and nucleus accumbens but potentiates hyperlocomotion: an in vivo microdialysis study. Neuropharmacology. vol 44. issue 5. 2003-06-23. PMID:12668045. |
the hippocampus and the nucleus accumbens (nac) are important structures for the modulation of spontaneous locomotor activity. |
2003-06-23 |
2023-08-12 |
rat |
| Ilona Vathy, Romana Slamberová, Agnes Rimanóczy, Michelle A Riley, Noffar Ba. Autoradiographic evidence that prenatal morphine exposure sex-dependently alters mu-opioid receptor densities in brain regions that are involved in the control of drug abuse and other motivated behaviors. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 3. 2003-06-23. PMID:12691773. |
the present study examined the effects of prenatal morphine exposure on mu-opioid receptor density in young adult male and female rats to assess the long-term alterations in several brain areas including the nucleus accumbens (nac), bed nucleus of stria terminalis (bnst), and the basolateral (bla), lateral (la), central (cea), and posteromedial cortical (pmcoa) amygdaloid nuclei. |
2003-06-23 |
2023-08-12 |
rat |
| Mark J Thomas, Robert C Malenk. Synaptic plasticity in the mesolimbic dopamine system. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 358. issue 1432. 2003-06-20. PMID:12740128. |
to address these potential functional roles of ltp and ltd, we have taken advantage of the powerful in vivo effects of drugs of abuse that exert their behavioural effects in large part by acting in the nucleus accumbens (nac) and ventral tegmental area (vta); the two major components of the mesolimbic dopamine system. |
2003-06-20 |
2023-08-12 |
Not clear |
| Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
rats were bilaterally implanted with microdialysis probes aimed at the vp and gp or nucleus accumbens (nac) and dorsal striatum (dstr). |
2003-06-11 |
2023-08-12 |
rat |
| M R Bauter, B J Brockel, D E Pankevich, M B Virgolini, D A Cory-Slecht. Glutamate and dopamine in nucleus accumbens core and shell: sequence learning versus performance. Neurotoxicology. vol 24. issue 2. 2003-05-07. PMID:12606295. |
this study sought to determine whether neurochemical changes associated with chronic postweaning lead (pb) exposure, namely, enhanced dopamine (da) activity and/or blockade of nmda function in nucleus accumbens (nac), underlie the learning impairments also associated with this pb regimen, and whether core or shell subregions of nucleus accumbens would be more important to such effects. |
2003-05-07 |
2023-08-12 |
rat |
| Aline Pinto, Michael Jankowski, Susan R Sesac. Projections from the paraventricular nucleus of the thalamus to the rat prefrontal cortex and nucleus accumbens shell: ultrastructural characteristics and spatial relationships with dopamine afferents. The Journal of comparative neurology. vol 459. issue 2. 2003-05-07. PMID:12640666. |
in the rat, the pvt projects to the deep layers of the medial prefrontal cortex (pfc) and to the shell of the nucleus accumbens (nac). |
2003-05-07 |
2023-08-12 |
rat |
| M J Bubar, L R McMahon, P De Deurwaerdère, U Spampinato, K A Cunningha. Selective serotonin reuptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens. Neuropharmacology. vol 44. issue 3. 2003-05-02. PMID:12604093. |
in the present study, the ability of the selective serotonin reuptake inhibitors (ssris) fluoxetine (10 mg/kg, ip) and fluvoxamine (10 and 20 mg/kg, ip) to alter cocaine (10 mg/kg, ip)-induced hyperactivity and da release in the nucleus accumbens (nac) was analyzed in male sprague-dawley rats. |
2003-05-02 |
2023-08-12 |
rat |
| Karin Schwartz, Gal Yadid, Abraham Weizman, Moshe Rehav. Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression. Brain research. vol 965. issue 1-2. 2003-05-01. PMID:12591135. |
vmat2 expression at the protein level was assessed by autoradiography using [(3)h]dihydrotetrabenazine ([(3)h]tbzoh) binding, in the prefrontal cortex, the striatum and its subregions, nucleus accumbens (nac), ventral tegmental area (vta) and the substantia nigra pars compacta (snc). |
2003-05-01 |
2023-08-12 |
rat |
| Timothy E Koeltzow, Jennifer D Austin, Paul Vezin. Behavioral sensitization to quinpirole is not associated with increased nucleus accumbens dopamine overflow. Neuropharmacology. vol 44. issue 1. 2003-04-30. PMID:12559127. |
this study assessed the relationship between extracellular nucleus accumbens (nac) dopamine (da) concentrations and sensitized locomotor activation following repeated administration of the da d2-like receptor agonist quinpirole. |
2003-04-30 |
2023-08-12 |
Not clear |