| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elena H Chartoff, Maria Papadopoulou, Christine Konradi, William A Carlezo. Dopamine-dependent increases in phosphorylation of cAMP response element binding protein (CREB) during precipitated morphine withdrawal in primary cultures of rat striatum. Journal of neurochemistry. vol 87. issue 1. 2003-11-12. PMID:12969258. |
altered gene expression within the nucleus accumbens (nac), a ventral component of the striatum that receives substantial dopaminergic input, may play a role in some of the motivational aspects of opiate withdrawal. |
2003-11-12 |
2023-08-12 |
rat |
| Jens Nagel, Henning Schladebach, Michael Koch, Isabel Schwienbacher, Christa E Müller, Wolfgang Haube. Effects of an adenosine A2A receptor blockade in the nucleus accumbens on locomotion, feeding, and prepulse inhibition in rats. Synapse (New York, N.Y.). vol 49. issue 4. 2003-11-10. PMID:12827647. |
the nucleus accumbens (nac) subserves behaviors governed by natural rewards, i.e., feeding or exploration, and has been implicated in control of prepulse inhibition (ppi), a measure of sensorimotor gating. |
2003-11-10 |
2023-08-12 |
rat |
| Kerry E Culm, Antonio M Lim, Julie A Onton, Ronald P Hamme. Reduced G(i) and G(o) protein function in the rat nucleus accumbens attenuates sensorimotor gating deficits. Brain research. vol 982. issue 1. 2003-10-30. PMID:12915235. |
ppi deficits can be produced in experimental animals by administration of selective d(2)-like dopamine receptor agonists in the nucleus accumbens (nac). |
2003-10-30 |
2023-08-12 |
rat |
| David Feifel, Paul D Shilling, Ronald Kuczenski, David S Sega. Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats. Neuroscience letters. vol 348. issue 3. 2003-10-06. PMID:12932815. |
in order to further clarify the role of cck-a receptors in the regulation of central da transmission, extracellular da levels in the nucleus accumbens (nac) and the caudate-putamen (cp) of oletf rats, and their non-mutant counterparts, long evans tokushimo otsuka rats, was assessed by microdialysis at baseline and in response to cocaine (15 mg/kg) and amphetamine (0.5 mg/kg) administration. |
2003-10-06 |
2023-08-12 |
rat |
| Hassen A Al-Amin, Nayef E Saadé, Munir Khani, Samir Atweh, Mohamed Jabe. Effects of chronic dizocilpine on acute pain and on mRNA expression of neuropeptides and the dopamine and glutamate receptors. Brain research. vol 981. issue 1-2. 2003-10-03. PMID:12885430. |
we measured the mrna expression, by in situ hybridization (ish), of various dopamine and glutamate receptors, and enkephalin (enk), dynorphin (dyn), and substance p (sp) in the striatum, nucleus accumbens (nac), piriform and cingulate cortex. |
2003-10-03 |
2023-08-12 |
rat |
| Eric A Engleman, William J McBride, Ting-Kai Li, Lawrence Lumeng, James M Murph. Ethanol drinking experience attenuates (-)sulpiride-induced increases in extracellular dopamine levels in the nucleus accumbens of alcohol-preferring (P) rats. Alcoholism, clinical and experimental research. vol 27. issue 3. 2003-09-24. PMID:12658107. |
this study examines the effects of local application of the da d(2) receptor antagonist (-)sulpiride (sul) on ethanol drinking of alcohol-preferring (p) rats, and extracellular da levels in the nucleus accumbens (nac) of p rats that were either ethanol-naive or had been chronically drinking ethanol. |
2003-09-24 |
2023-08-12 |
rat |
| Zhu Li, Junji Ichikawa, Herbert Y Meltze. A comparison of the effects of loxapine with ziprasidone and thioridazine on the release of dopamine and acetylcholine in the prefrontal cortex and nucleus accumbens. Psychopharmacology. vol 167. issue 3. 2003-09-24. PMID:12664192. |
atypical, but not typical, antipsychotic drugs (apds), produce preferential increases in dopamine (da) and acetylcholine (ach) release in rat medial prefrontal cortex (mpfc) compared to the nucleus accumbens (nac). |
2003-09-24 |
2023-08-12 |
rat |
| O Giorgi, D Lecca, G Piras, P Driscoll, M G Cord. Dissociation between mesocortical dopamine release and fear-related behaviours in two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions. The European journal of neuroscience. vol 17. issue 12. 2003-09-24. PMID:12823478. |
in contrast, in the shell compartment of the nucleus accumbens (nac shell), tp caused a small increase in da output only in rla/verh rats, whereas ptz and zk 93426 had no significant effect on either line. |
2003-09-24 |
2023-08-12 |
rat |
| b' Marzena Karcz-Kubicha, Davide Quarta, Bruce T Hope, Katerina Antoniou, Christa E M\\xc3\\xbcller, Marisela Morales, Charles W Schindler, Steven R Goldberg, Sergi Ferr\\xc3\\xa. Enabling role of adenosine A1 receptors in adenosine A2A receptor-mediated striatal expression of c-fos. The European journal of neuroscience. vol 18. issue 2. 2003-09-24. PMID:12887411.' |
using c-fos immunohistochemistry as an indicator of neural activity, we examined the effects of coactivation of a1rs and a2ars on neural activity and their mechanism of interaction in the caudate-putamen, nucleus accumbens (nac) and prefrontal cortex in rats. |
2003-09-24 |
2023-08-12 |
rat |
| Samuel B Kombian, Kethireddy V V Ananthalakshmi, Subramanian S Parvathy, Wandikayi C Matow. Dopamine and adenosine mediate substance P-induced depression of evoked IPSCs in the rat nucleus accumbens in vitro. The European journal of neuroscience. vol 18. issue 2. 2003-09-24. PMID:12887412. |
the major projection cells of the nucleus accumbens (nac) are under a strong inhibitory influence from gabaergic afferents and depend on afferent excitation to produce their output. |
2003-09-24 |
2023-08-12 |
rat |
| Carrie L Heusner, Thomas S Hnasko, Mark S Szczypka, Yuhong Liu, Matthew J During, Richard D Palmite. Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain research. vol 980. issue 2. 2003-09-16. PMID:12867267. |
restoration of dopamine specifically to the nucleus accumbens (nac) of dd mice completely restores the ability of these mice to respond to amphetamine. |
2003-09-16 |
2023-08-12 |
mouse |
| A C Riegel, S F Ali, E D Frenc. Toluene-induced locomotor activity is blocked by 6-hydroxydopamine lesions of the nucleus accumbens and the mGluR2/3 agonist LY379268. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 8. 2003-09-12. PMID:12784113. |
thus, the present study was undertaken using two different approaches to determine whether toluene-induced locomotor hyperactivity is also ultimately dependent upon da neurotransmission in the mesolimbic nucleus accumbens (nac). |
2003-09-12 |
2023-08-12 |
rat |
| A Charara, A A Grac. Dopamine receptor subtypes selectively modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 8. 2003-09-12. PMID:12799620. |
the nucleus accumbens (nac) receives excitatory afferents from several cortical and limbic regions and dense dopaminergic inputs from the ventral tegmental area. |
2003-09-12 |
2023-08-12 |
rat |
| K D Carr, Y Tsimberg, Y Berman, N Yamamot. Evidence of increased dopamine receptor signaling in food-restricted rats. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831870. |
in addition, fos-immunostaining induced by skf-82958 in caudate-putamen (cpu) and nucleus accumbens (nac) was greater in food-restricted than ad libitum-fed rats, as was staining induced by quinpirole in globus pallidus and ventral pallidum. |
2003-09-05 |
2023-08-12 |
rat |
| Makoto Inoue, Masayoshi Mishina, Hiroshi Ued. Locus-specific rescue of GluRepsilon1 NMDA receptors in mutant mice identifies the brain regions important for morphine tolerance and dependence. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 16. 2003-09-03. PMID:12878694. |
in c57bl/6j mice treated with chronic morphine after tolerance paradigm, the glurepsilon1 protein expression significantly increased in periaqueductal gray matter (pag), ventral tegmental area (vta) and nucleus accumbens (nac), but not amygdala or hippocampus. |
2003-09-03 |
2023-08-12 |
mouse |
| Marcelo Febo, Loida A González-Rodríguez, David E Capó-Ramos, Naggai Y González-Segarra, Annabell C Segarr. Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats. Journal of neurochemistry. vol 86. issue 2. 2003-08-21. PMID:12871581. |
d2/d3-stimulated [35s]guanosine 5'-(gamma-thio) triphosphate (gtpgammas) binding was assessed in the cingulate cortex area 2 (cg2), striatum (str), nucleus accumbens (nac) and ventral tegmental area (vta). |
2003-08-21 |
2023-08-12 |
rat |
| G Hotsenpiller, M E Wol. Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676144. |
considering the importance of glutamate transmission in the nucleus accumbens (nac) during associative responses to reward-related stimuli, the effect of baclofen on extracellular levels of glutamate in the nac was tested with microdialysis. |
2003-08-13 |
2023-08-12 |
human |
| Alexander F Hoffman, Murat Oz, Tara Caulder, Carl R Lupic. Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 12. 2003-08-05. PMID:12832502. |
the rewarding properties of the psychoactive constituents of marijuana, termed "cannabinoids," may reflect actions on synaptic transmission in the nucleus accumbens (nac). |
2003-08-05 |
2023-08-12 |
rat |
| Ryuichi Takahata, Bita Moghadda. Activation of glutamate neurotransmission in the prefrontal cortex sustains the motoric and dopaminergic effects of phencyclidine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700703. |
although the major cellular correlate of this behavioral activation is thought to be an increase in dopamine neurotransmission in the nucleus accumbens (nac), recent evidence suggests that nac dopamine is neither necessary nor sufficient to elicit nmda antagonist-induced motor effects. |
2003-08-04 |
2023-08-12 |
Not clear |
| Erkki Tupala, Håkan Hall, Kim Bergström, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jukka Hiltunen, Jari Tiihone. Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics. Synapse (New York, N.Y.). vol 48. issue 4. 2003-07-25. PMID:12687640. |
the role of the mesolimbic da in brain ethanol reinforcement is well established, with nucleus accumbens (nac) serving as a major terminal area of this system, whereas dorsal striatum is more associated with motor control. |
2003-07-25 |
2023-08-12 |
human |