| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lily Alvarez-Jaimes, Ilham Polis, Loren H Parson. Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB1 antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 10. 2008-12-22. PMID:18059440. |
in this study, we evaluated alterations in cue-induced reinstatement of heroin-seeking behavior produced by infusions of the cb(1) receptor antagonist sr 141716a (0, 0.3 and 3 microg per side) delivered into the prefrontal cortex (pfc), nucleus accumbens (nac), and basolateral amygdala (bla) of rats. |
2008-12-22 |
2023-08-12 |
rat |
| R Numa, R Kohen, T Poltyrev, R Yak. Tempol diminishes cocaine-induced oxidative damage and attenuates the development and expression of behavioral sensitization. Neuroscience. vol 155. issue 3. 2008-12-18. PMID:18619523. |
acute cocaine treatment significantly elevated os markers in prefrontal cortex (pfc) and nucleus accumbens (nac) in rats, both in slices and following a single cocaine injection, which corresponded with a decrease in total antioxidant capacity (tac). |
2008-12-18 |
2023-08-12 |
rat |
| A Ishikawa, F Ambroggi, S M Nicola, H L Field. Contributions of the amygdala and medial prefrontal cortex to incentive cue responding. Neuroscience. vol 155. issue 3. 2008-12-18. PMID:18640246. |
reward-seeking behavior is controlled by neuronal circuits that include the basolateral nucleus of amygdala (bla), medial prefrontal cortex (mpfc), nucleus accumbens (nac) and ventral tegmental area. |
2008-12-18 |
2023-08-12 |
rat |
| Amine Bahi, Frederic Boyer, Vijay Chandrasekar, Jean-Luc Dreye. Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats. Psychopharmacology. vol 199. issue 2. 2008-12-16. PMID:18551281. |
bdnf action is mediated by the trkb receptor-tyrosine kinase, and both bdnf and trkb transcripts are widely expressed in the rat mesolimbic pathway, including the nucleus accumbens (nac) and the ventral tegmentum area (vta). |
2008-12-16 |
2023-08-12 |
rat |
| M Ellgren, A Artmann, O Tkalych, A Gupta, H S Hansen, S H Hansen, L A Devi, Y L Hur. Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 11. 2008-12-16. PMID:18674887. |
we recently observed that adult rats pre-exposed to delta-9-tetrahydrocannabinol (thc) during adolescence self-administered higher amounts of heroin and had selective impairments of the enkephalin opioid system within the nucleus accumbens (nac) implicated in reward-related behavior. |
2008-12-16 |
2023-08-12 |
rat |
| Qiang Chen, Xueying Xiong, Tong H Lee, Yingmiao Liu, William C Wetsel, Xiuwu Zhan. Neural plasticity and addiction: integrin-linked kinase and cocaine behavioral sensitization. Journal of neurochemistry. vol 107. issue 3. 2008-12-16. PMID:18702665. |
conditional inhibition of ilk expression was established in the nucleus accumbens (nac) core by microinjecting recombinant adeno-associated virus-carrying, tetracycline-on-regulated small interfering rna which reversed the chronic cocaine-induced psychomotor sensitization, as well as the changes in protein kinase b ser473 phosphorylation, dendritic density, and dendritic spine numbers locally. |
2008-12-16 |
2023-08-12 |
Not clear |
| Tadimeti S Rao, Pamala B Adams, Lucia D Correa, Emily M Santori, Aida I Sacaan, Richard T Reid, Nicholas D P Cosfor. Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist. Brain research. vol 1234. 2008-12-08. PMID:18692487. |
in vitro, sib-1508y increased dopamine (da) release from slices of rat striatum, nucleus accumbens (nac), olfactory tubercles (ot) and prefrontal cortices (pfc) in a concentration-dependent manner. |
2008-12-08 |
2023-08-12 |
rat |
| N Benturquia, T Le Marec, J-M Scherrmann, F Nobl. Effects of nitrous oxide on dopamine release in the rat nucleus accumbens and expectation of reward. Neuroscience. vol 155. issue 2. 2008-12-03. PMID:18571333. |
levels of da, in the nucleus accumbens (nac), in awake and freely moving rats during positive place conditioning after morphine chronic treatment has been measured by microdialysis. |
2008-12-03 |
2023-08-12 |
mouse |
| László Köles, Zoltán Gerevich, Holger Kittner, Ute Krügel, Heike Franke, Péter Illé. [Purinergic modulation of the brain dopaminergic transmission: behavioral-pharmacologic conclusions]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 10. issue 2. 2008-12-03. PMID:18959141. |
the ventral tegmental area (vta), the prefrontal cortex and the nucleus accumbens (nac) are key elements of the mesolimbic dopaminergic system. |
2008-12-03 |
2023-08-12 |
Not clear |
| Pornnarin Taepavarapruk, John G Howland, Soyon Ahn, Anthony G Phillip. Neural circuits engaged in ventral hippocampal modulation of dopamine function in medial prefrontal cortex and ventral striatum. Brain structure & function. vol 213. issue 1-2. 2008-12-02. PMID:18288486. |
dopamine (da) transmission in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) is crucial for various cognitive processes. |
2008-12-02 |
2023-08-12 |
rat |
| Pauline Belujon, Anthony A Grac. Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 39. 2008-11-12. PMID:18815264. |
the nucleus accumbens (nac) is an integral part of limbic circuits proposed to play a central role in the pathophysiology of schizophrenia, and is positioned to integrate information from limbic and cortical regions, including the medial prefrontal cortex (mpfc) and the hippocampus. |
2008-11-12 |
2023-08-12 |
rat |
| Lino Becerra, David Borsoo. Signal valence in the nucleus accumbens to pain onset and offset. European journal of pain (London, England). vol 12. issue 7. 2008-11-10. PMID:18226937. |
of particular interest is the nucleus accumbens (nac), a brain substrate known to be involved in reward-aversion processing, whose activation valence has been observed to be opposite in response to reward or aversive stimuli. |
2008-11-10 |
2023-08-12 |
human |
| Marcelo T Marin, Fábio C Cruz, Cleopatra S Planet. Cocaine-induced behavioral sensitization in adolescent rats endures until adulthood: lack of association with GluR1 and NR1 glutamate receptor subunits and tyrosine hydroxylase. Pharmacology, biochemistry, and behavior. vol 91. issue 1. 2008-11-06. PMID:18640148. |
adaptations in dopamine and glutamate neurotransmission in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) seem to mediate psychostimulant-induced behavioral sensitization. |
2008-11-06 |
2023-08-12 |
rat |
| Mark J Hunt, Rene Garcia, Charles H Large, Stefan Kasick. Modulation of high-frequency oscillations associated with NMDA receptor hypofunction in the rodent nucleus accumbens by lamotrigine. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 5. 2008-11-05. PMID:18514376. |
we reported recently that ketamine can increase the power of high-frequency oscillations (hfo) in the rodent nucleus accumbens (nac), a region implicated in the pathophysiology of schizophrenia. |
2008-11-05 |
2023-08-12 |
rat |
| Kyoung-Shim Kim, Ko-Woon Lee, In-Sun Baek, Chae-Moon Lim, Vaishnav Krishnan, Ja-Kyeong Lee, Eric J Nestler, Pyung-Lim Ha. Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. Journal of neurochemistry. vol 107. issue 1. 2008-11-03. PMID:18673448. |
type 5 adenylyl cyclase (ac5) is highly concentrated in the dorsal striatum and nucleus accumbens (nac), two brain areas which have been implicated in motor function, reward, and emotion. |
2008-11-03 |
2023-08-12 |
mouse |
| Deanna L Wallace, Vincent Vialou, Loretta Rios, Tiffany L Carle-Florence, Sumana Chakravarty, Arvind Kumar, Danielle L Graham, Thomas A Green, Anne Kirk, Sergio D Iñiguez, Linda I Perrotti, Michel Barrot, Ralph J DiLeone, Eric J Nestler, Carlos A Bolaños-Guzmá. The influence of DeltaFosB in the nucleus accumbens on natural reward-related behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 41. 2008-11-03. PMID:18842886. |
the transcription factor deltafosb (deltafosb), induced in nucleus accumbens (nac) by chronic exposure to drugs of abuse, has been shown to mediate sensitized responses to these drugs. |
2008-11-03 |
2023-08-12 |
Not clear |
| Qiang Chen, Xueying Xiong, Tong H Lee, Yingmiao Liu, Qi-An Sun, William Wetsel, Xiuwu Zhan. Adeno-associated virus-mediated ILK gene silencing in the rat NAc core. Journal of neuroscience methods. vol 173. issue 2. 2008-10-24. PMID:18602949. |
in this study we established conditional silencing of integrin-linked kinase (ilk) expression in sprague-dawley rat brain by microinjection of raav-2-carrying, tet-on-regulated sirna expression cassette into nucleus accumbens (nac) core and induction with doxycycline. |
2008-10-24 |
2023-08-12 |
rat |
| Iván Pérez-Neri, Israel Méndez-Sánchez, Sergio Montes, Camilo Río. Acute dehydroepiandrosterone treatment exerts different effects on dopamine and serotonin turnover ratios in the rat corpus striatum and nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 32. issue 6. 2008-10-22. PMID:18585426. |
to explore if dhea modulates da and 5-ht metabolism we analyzed the content of both neurotransmitters and their metabolites in the rat corpus striatum (cs) and nucleus accumbens (nac) 2 h after steroid administration (30, 60 and 120 mg/kg i.p.). |
2008-10-22 |
2023-08-12 |
rat |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Stephanie J Crag. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 9. 2008-10-08. PMID:18033235. |
we explored the role of alpha6beta2*-nachrs in the nucleus accumbens (nac) and caudate-putamen (cpu) by observing action potential-dependent da release from synapses in real-time using fast-scan cyclic voltammetry at carbon-fiber microelectrodes in mouse striatal slices. |
2008-10-08 |
2023-08-12 |
mouse |
| K-W Lee, Y-H Tian, I-J You, S-H Kwon, R-R Ha, S-Y Lee, H-C Kim, C-G Jan. Blockade of M1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect. Neuroscience. vol 153. issue 4. 2008-10-08. PMID:18455881. |
dicyclomine, an m1r antagonist, did not affect the psychomotor effect of meth, but it attenuated meth-induced increases in the dopamine (da) efflux in the nucleus accumbens (nac). |
2008-10-08 |
2023-08-12 |
mouse |