| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sun Jung Bang, Kathryn G Common. Forebrain GABAergic projections from the dorsal raphe nucleus identified by using GAD67-GFP knock-in mice. The Journal of comparative neurology. vol 520. issue 18. 2013-04-18. PMID:22605640. |
projections of gad67-gfp neurons to the prefrontal cortex (pfc), nucleus accumbens (nac), and lateral hypothalamus (lh) were evaluated by using retrograde tract tracing. |
2013-04-18 |
2023-08-12 |
mouse |
| M L Perreault, A Hasbi, M Alijaniaram, B F O'Dowd, S R Georg. Reduced striatal dopamine D1-D2 receptor heteromer expression and behavioural subsensitivity in juvenile rats. Neuroscience. vol 225. 2013-04-16. PMID:22986162. |
in adult rat striatum the dopamine d1-d2 receptor heteromer is expressed selectively in a subset of medium spiny neurons (msns) that coexpress the dopamine d1 and d2 receptors (d1r and d2r) as well as dynorphin (dyn) and enkephalin (enk), with higher coexpression in nucleus accumbens (nac) and much lower in the caudate putamen (cp). |
2013-04-16 |
2023-08-12 |
rat |
| D Shabashov, E Shohami, R Yak. Inactivation of PKMζ in the NAc shell abolished cocaine-conditioned reward. Journal of molecular neuroscience : MN. vol 47. issue 3. 2013-04-11. PMID:22127928. |
here we show that inhibition of pkmζ in the nucleus accumbens (nac) shell, a major component of the reward system that plays an important role in mediating drug craving and relapse, by a selective inhibitor ζ inhibitory peptide (zip), abolished cocaine-induced conditioned place preference (cpp). |
2013-04-11 |
2023-08-12 |
Not clear |
| E M Nikulina, M J Lacagnina, S Fanous, J Wang, R P Hamme. Intermittent social defeat stress enhances mesocorticolimbic ΔFosB/BDNF co-expression and persistently activates corticotegmental neurons: implication for vulnerability to psychostimulants. Neuroscience. vol 212. 2013-04-01. PMID:22521816. |
stress exposure increased bdnf immunoreactivity in anterior cingulate, prelimbic and infralimbic regions of the prefrontal cortex (pfc), medial amygdala (amy), nucleus accumbens (nac) and vta; Δfosb labeling in anterior cingulate cortex (acg) and nucleus accumbens; and Δfosb/bdnf co-expression in prelimbic cortex (pl), nucleus accumbens and medial amygdala. |
2013-04-01 |
2023-08-12 |
rat |
| Xuan Li, M R DeJoseph, Janice H Urban, Amine Bahi, Jean-Luc Dreyer, Gloria E Meredith, Kerstin A Ford, Carrie R Ferrario, Jessica A Loweth, Marina E Wol. Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 3. 2013-04-01. PMID:23325250. |
we investigated the role of bdnf in the rat nucleus accumbens (nac) in the incubation of cocaine craving over 3 months of withdrawal from extended access cocaine self-administration. |
2013-04-01 |
2023-08-12 |
rat |
| Veronica M Afonso, Waqqas M Shams, Daniel Jin, Alison S Flemin. Distal pup cues evoke dopamine responses in hormonally primed rats in the absence of pup experience or ongoing maternal behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 6. 2013-04-01. PMID:23392661. |
during the early postpartum period or following estrogen/progesterone administration, pups elicit maternal behavior accompanied by a robust dopamine (da) response in the nucleus accumbens (nac) of female rats (afonso et al., 2009). |
2013-04-01 |
2023-08-12 |
rat |
| Mohammad Reza Zarrindast, Solmaz Khalifeh, Ameneh Rezayof, Parvin Rostami, Arash Aghamohammadi Sereshki, Maryam Zahmatkes. Involvement of rat dopaminergic system of nucleus accumbens in nicotine-induced anxiogenic-like behaviors. Brain research. vol 1460. 2013-03-25. PMID:22595749. |
the objective of the present study was to investigate the involvement of dopamine d₁ and d₂ receptors of the nucleus accumbens (nac) shell in the anxiogenic-like effect of intra-central amygdala (cea) nicotine administration. |
2013-03-25 |
2023-08-12 |
rat |
| Daniel J Christoffel, Sam A Golden, Mitra Heshmati, Ami Graham, Shari Birnbaum, Rachael L Neve, Georgia E Hodes, Scott J Russ. Effects of inhibitor of κB kinase activity in the nucleus accumbens on emotional behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 12. 2013-03-22. PMID:22781845. |
chronic social defeat stress of mice increases iκk activity in the nucleus accumbens (nac) and this increase is strongly correlated to depression-like behaviors. |
2013-03-22 |
2023-08-12 |
mouse |
| Saïd Kourrich, Teruo Hayashi, Jian-Ying Chuang, Shang-Yi Tsai, Tsung-Ping Su, Antonello Bonc. Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine. Cell. vol 152. issue 1-2. 2013-03-19. PMID:23332758. |
we found that cocaine exposure triggers a sig-1r-dependent upregulation of d-type k(+) current in the nucleus accumbens (nac) that results in neuronal hypoactivity and thereby enhances behavioral cocaine response. |
2013-03-19 |
2023-08-12 |
Not clear |
| Darlene A Mitrano, Jason P Schroeder, Yoland Smith, James J Cortright, Nancy Bubula, Paul Vezina, David Weinshenke. α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 9. 2013-03-17. PMID:22588352. |
although α1ar signaling in the prefrontal cortex (pfc) promotes mesolimbic transmission and drug-induced behaviors, the potential contribution of α1ars in other parts of the pathway, such as the ventral tegmental area (vta) and nucleus accumbens (nac), has not been investigated before. |
2013-03-17 |
2023-08-12 |
Not clear |
| M O Job, J Licata, G W Hubert, M J Kuha. Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats. Brain research. vol 1482. 2013-03-12. PMID:22975438. |
in order to examine the effect of cocaine and amphetamine regulated transcript (cart) peptide depletion in adult rats, cart shrnas or scrambled control shrnas were administered bilaterally into the nucleus accumbens (nac). |
2013-03-12 |
2023-08-12 |
rat |
| Elizabeth N Holly, Akiko Shimamoto, Joseph F Debold, Klaus A Micze. Sex differences in behavioral and neural cross-sensitization and escalated cocaine taking as a result of episodic social defeat stress in rats. Psychopharmacology. vol 224. issue 1. 2013-03-08. PMID:22926005. |
episodic social defeat stress results in cross-sensitization to cocaine, characterized by augmentation of locomotor activity, dopamine (da) levels in the nucleus accumbens (nac), and cocaine self-administration during a 24-h "binge" in male rats. |
2013-03-08 |
2023-08-12 |
rat |
| Anna Suska, Brian R Lee, Yanhua H Huang, Yan Dong, Oliver M Schlüte. Selective presynaptic enhancement of the prefrontal cortex to nucleus accumbens pathway by cocaine. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 2. 2013-03-07. PMID:23267100. |
the nucleus accumbens (nac) regulates motivated behavior by, in part, processing excitatory synaptic projections from several brain regions. |
2013-03-07 |
2023-08-12 |
rat |
| Maria A Esparza, Flavia Bollati, Constanza Garcia-Keller, Miriam B Virgolini, Lidia M Lopez, Alicia Brusco, Hao-Wei Shen, Peter W Kalivas, Liliana M Cancel. Stress-induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei. The European journal of neuroscience. vol 36. issue 8. 2013-03-06. PMID:22882295. |
this study investigated the consequence of repeated stress on actin cytoskeleton remodeling in the nucleus accumbens (nac) and prefrontal cortex (pfc), and the involvement of this remodeling in the expression of stress-induced motor cross-sensitization with cocaine. |
2013-03-06 |
2023-08-12 |
rat |
| Mei-Hong Qiu, Wei Liu, Wei-Min Qu, Yoshihiro Urade, Jun Lu, Zhi-Li Huan. The role of nucleus accumbens core/shell in sleep-wake regulation and their involvement in modafinil-induced arousal. PloS one. vol 7. issue 9. 2013-03-06. PMID:23029032. |
we proposed that the nucleus accumbens (nac) that receives the ventral tegmental area dopamine inputs play an important role not only in reward and addiction but also in sleep-wake cycle and in mediating modafinil-induced arousal. |
2013-03-06 |
2023-08-12 |
Not clear |
| Przemysław Biliński, Andrzej Wojtyła, Lucyna Kapka-Skrzypczak, Roman Chwedorowicz, Małgorzata Cyranka, Tadeusz Studzińsk. Epigenetic regulation in drug addiction. Annals of agricultural and environmental medicine : AAEM. vol 19. issue 3. 2013-03-04. PMID:23020045. |
recent data suggest that repeated exposure to certain drugs promotes changes in levels of histone acetylation, phosphorylation and methylation, together with alterations in dna methylation levels in the neurons of the brain reward centre, localised in the nucleus accumbens (nac) region of the limbic system. |
2013-03-04 |
2023-08-12 |
Not clear |
| Dipesh Chaudhury, Jessica J Walsh, Allyson K Friedman, Barbara Juarez, Stacy M Ku, Ja Wook Koo, Deveroux Ferguson, Hsing-Chen Tsai, Lisa Pomeranz, Daniel J Christoffel, Alexander R Nectow, Mats Ekstrand, Ana Domingos, Michelle S Mazei-Robison, Ezekiell Mouzon, Mary Kay Lobo, Rachael L Neve, Jeffrey M Friedman, Scott J Russo, Karl Deisseroth, Eric J Nestler, Ming-Hu Ha. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. vol 493. issue 7433. 2013-03-04. PMID:23235832. |
furthermore, we show differences in projection-pathway specificity in promoting stress susceptibility: phasic activation of vta neurons projecting to the nucleus accumbens (nac), but not to the medial prefrontal cortex (mpfc), induced susceptibility to social-defeat stress. |
2013-03-04 |
2023-08-12 |
mouse |
| Takatoshi Hikida, Satoshi Yawata, Takashi Yamaguchi, Teruko Danjo, Toshikuni Sasaoka, Yanyan Wang, Shigetada Nakanish. Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 1. 2013-02-27. PMID:23248274. |
inputs of the nucleus accumbens (nac) in this circuitry are transmitted through two parallel pathways: the striatonigral direct pathway and the striatopallidal indirect pathway. |
2013-02-27 |
2023-08-12 |
Not clear |
| Michael A Benneyworth, Joseph T Coyl. Altered acquisition and extinction of amphetamine-paired context conditioning in genetic mouse models of altered NMDA receptor function. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22763616. |
when drug exposure is paired with a specific environment, contextual cues can control conditioned responses, context-specific sensitization, and alterations in dendritic morphology in the nucleus accumbens (nac). |
2013-02-26 |
2023-08-12 |
mouse |
| Yosefu Arime, Yoshiyuki Kasahara, F Scott Hall, George R Uhl, Ichiro Sor. Cortico-subcortical neuromodulation involved in the amelioration of prepulse inhibition deficits in dopamine transporter knockout mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22781838. |
to clarify these mechanisms, ppi was tested after microinjections of nisoxetine into the medial prefrontal cortex (mpfc) or nucleus accumbens (nac) in wildtype (wt) and dat ko mice. |
2013-02-26 |
2023-08-12 |
mouse |