| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy A Herrold, Amanda L Persons, T Celeste Napie. Cellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetamine. Journal of neurochemistry. vol 126. issue 4. 2013-10-23. PMID:23711322. |
step61 levels, and cellular distribution/expression of ampar subunits (glua1, glua2) and mglu5, were evaluated via a protein cross-linking assay in medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral pallidum (vp) harvested 1 day after acute, or fourteen days after repeated morphine (8 mg/kg) or methamphetamine (1 mg/kg) (treatments producing behavioral sensitization). |
2013-10-23 |
2023-08-12 |
rat |
| Anna M Belle, Catarina Owesson-White, Natalie R Herr, Regina M Carelli, R Mark Wightma. Controlled iontophoresis coupled with fast-scan cyclic voltammetry/electrophysiology in awake, freely moving animals. ACS chemical neuroscience. vol 4. issue 5. 2013-10-22. PMID:23480099. |
we also examined changes in the firing rate of nucleus accumbens (nac) neurons in awake animals during and after brief (15 s) iontophoretic ejections of sch 23390 (d1 receptor antagonist) or raclopride. |
2013-10-22 |
2023-08-12 |
rat |
| Niall W Duncan, Christine Wiebking, Brice Tiret, Malgorzata Marjańska, Malgoranza Marjańska, Dave J Hayes, Oliver Lyttleton, Julien Doyon, Georg Northof. Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans. PloS one. vol 8. issue 4. 2013-10-22. PMID:23573246. |
the subcortical target regions were the nucleus accumbens (nac), dorsomedial thalamus (dmt), and periaqueductal grey (pag). |
2013-10-22 |
2023-08-12 |
Not clear |
| Soyon Ahn, Anthony G Phillip. Daily monitoring of dopamine efflux reveals a short-lasting occlusion of the dopamine agonist properties of d-amphetamine by dopamine transporter blockers GBR 12909 and methylphenidate. ACS chemical neuroscience. vol 4. issue 5. 2013-10-22. PMID:23586444. |
in vivo brain microdialysis was used in conjunction with "reverse-dialysis" of the dopamine-transporter (dat) blockers gbr 12909 and methylphenidate (mph) to observe the temporal course of their effects on d-amphetamine (d-amph)-induced increases in dopamine (da) efflux in the rat nucleus accumbens (nac). |
2013-10-22 |
2023-08-12 |
rat |
| L Adermark, S Jonsson, B Söderpalm, M Ericso. Region-specific depression of striatal activity in Wistar rat by modest ethanol consumption over a ten-month period. Alcohol (Fayetteville, N.Y.). vol 47. issue 4. 2013-10-21. PMID:23601928. |
the nucleus accumbens (nac) is the primary target for the mesolimbic dopamine system and a key brain region for the reinforcing effects displayed by drugs of abuse, including ethanol. |
2013-10-21 |
2023-08-12 |
rat |
| Yan Zhou, Giancarlo Colombo, Keiichi Niikura, Mauro A M Carai, Teresa Femenía, Maria S García-Gutiérrez, Jorge Manzanares, Ann Ho, Gian Luigi Gessa, Mary Jeanne Kree. Voluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats. Alcoholism, clinical and experimental research. vol 37 Suppl 1. 2013-10-17. PMID:22724395. |
however, the alcohol effect on pomc gene expression has not been studied in rodent mesolimbic regions, such as the nucleus accumbens (nac). |
2013-10-17 |
2023-08-12 |
rat |
| Tatiana V Lipina, Paul J Fletcher, Frankie H Lee, Albert H C Wong, John C Rode. Disrupted-in-schizophrenia-1 Gln31Leu polymorphism results in social anhedonia associated with monoaminergic imbalance and reduction of CREB and β-arrestin-1,2 in the nucleus accumbens in a mouse model of depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 3. 2013-10-17. PMID:23011268. |
first, we found reduced levels of dopamine, serotonin and norepinephrine in the nucleus accumbens (nac) of disc1-q31l mutants. |
2013-10-17 |
2023-08-12 |
mouse |
| Daniel J Tobiansky, Peter G Roma, Tomoko Hattori, Ryan G Will, Victoria L Nutsch, Juan M Domingue. The medial preoptic area modulates cocaine-induced activity in female rats. Behavioral neuroscience. vol 127. issue 2. 2013-10-01. PMID:23565937. |
here, using a female rat model, we show that the mpoa innervates the vta in a region-specific manner, that lesions of the mpoa augment cocaine-induced fos expression in the nucleus accumbens (nac) and cocaine-induced conditioned place preference. |
2013-10-01 |
2023-08-12 |
rat |
| Kathryn Schierberl, Thomas Giordano, Shirish Satpute, Jin Hao, Gagandeep Kaur, Franz Hofmann, Sven Moosmang, Joerg Striessnig, Anjali Rajadhyaksh. Cav 1.3 L-type Ca ( 2+) channels mediate long-term adaptation in dopamine D2L-mediated GluA1 trafficking in the dorsal striatum following cocaine exposure. Channels (Austin, Tex.). vol 6. issue 1. 2013-09-30. PMID:22419037. |
taken together with our recently published findings examining similar phenomena in the nucleus accumbens (nac), these results underscore the utilization of divergent molecular mechanisms in the dstr, in mediating cocaine-induced persistent behavioral changes. |
2013-09-30 |
2023-08-12 |
mouse |
| Taehyun Kim, David J Hinton, Sandy Johng, Jia Bei Wang, Doo-Sup Cho. Levo-tetrahydropalmatine decreases ethanol drinking and antagonizes dopamine D2 receptor-mediated signaling in the mouse dorsal striatum. Behavioural brain research. vol 244. 2013-09-30. PMID:23376703. |
our results indicated that a single injection of l-thp increased active phosphorylated forms of pka, akt and erk in the caudate-putamen (cpu), but not in the nucleus accumbens (nac), of alcohol naïve mice. |
2013-09-30 |
2023-08-12 |
mouse |
| Zhi Yi Ong, Ayumi F Wanasuria, Mark Z P Lin, Jennifer Hiscock, Beverly S Muhlhausle. Chronic intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system. Appetite. vol 65. 2013-09-30. PMID:23402719. |
the nucleus accumbens (nac) was isolated and mrna expression of tyrosine hydroxylase (th), dopamine active transporter (dat), d1 and d2 dopamine receptors, and μ-opioid receptor determined by qrt-pcr. |
2013-09-30 |
2023-08-12 |
rat |
| Xiaoting Wang, Michael E Cahill, Craig T Werner, Daniel J Christoffel, Sam A Golden, Zhong Xie, Jessica A Loweth, Michela Marinelli, Scott J Russo, Peter Penzes, Marina E Wol. Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 27. 2013-09-30. PMID:23825406. |
it is well established that behavioral sensitization to cocaine is accompanied by increased spine density and ampa receptor (ampar) transmission in the nucleus accumbens (nac), but two major questions remain unanswered. |
2013-09-30 |
2023-08-12 |
rat |
| Evan N Graf, Robert A Wheeler, David A Baker, Amanda L Ebben, Jonathan E Hill, Jayme R McReynolds, Mykel A Robble, Oliver Vranjkovic, Daniel S Wheeler, John R Mantsch, Paul J Gasse. Corticosterone acts in the nucleus accumbens to enhance dopamine signaling and potentiate reinstatement of cocaine seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 29. 2013-09-27. PMID:23864669. |
corticosterone potentiated cocaine-induced increases in extracellular dopamine in the nucleus accumbens (nac), and pharmacological blockade of nac dopamine receptors blocked corticosterone-induced potentiation of reinstatement. |
2013-09-27 |
2023-08-12 |
rat |
| Zhen-Yu Ren, Meng-Meng Liu, Yan-Xue Xue, Zeng-Bo Ding, Li-Fen Xue, Suo-Di Zhai, Lin L. A critical role for protein degradation in the nucleus accumbens core in cocaine reward memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 5. 2013-09-17. PMID:23303053. |
first, we found that polyubiquitinated protein expression levels and polyubiquitinated n-ethylmaleimide-sensitive fusion (nsf) markedly increased 15 min after retrieval while nsf protein levels decreased 1 h after retrieval in the synaptosomal membrane fraction in the nucleus accumbens (nac) core. |
2013-09-17 |
2023-08-12 |
rat |
| Colin M Stopper, Shahin Khayambashi, Stan B Floresc. Receptor-specific modulation of risk-based decision making by nucleus accumbens dopamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 5. 2013-09-17. PMID:23303055. |
the nucleus accumbens (nac) serves as an integral node within cortico-limbic circuitry that regulates various forms of cost-benefit decision making. |
2013-09-17 |
2023-08-12 |
rat |
| Jacqueline Vazquez-DeRose, Gregory Stauber, Taline V Khroyan, Xinmin Simon Xie, Nurulain T Zaveri, Lawrence Tol. Retrodialysis of N/OFQ into the nucleus accumbens shell blocks cocaine-induced increases in extracellular dopamine and locomotor activity. European journal of pharmacology. vol 699. issue 1-3. 2013-09-02. PMID:23219985. |
n/ofq suppresses extracellular dopamine in the nucleus accumbens (nac) after intracerebroventricular injection. |
2013-09-02 |
2023-08-12 |
rat |
| Hailiang Yan, Long-Chuan Y. Influences of calcitonin gene-related peptide on mu opioid receptors in nucleus accumbens neurons of rats. Neuropeptides. vol 47. issue 2. 2013-08-30. PMID:23211530. |
the mu opioid receptor (mor) has been shown to participate in the analgesic effect of the calcitonin gene-related peptide (cgrp) in the nucleus accumbens (nac) of adult rats. |
2013-08-30 |
2023-08-12 |
rat |
| Stephanie Tobin, Firas Sedki, Zarish Abbas, Uri Shale. Antagonism of the dopamine D1-like receptor in mesocorticolimbic nuclei attenuates acute food deprivation-induced reinstatement of heroin seeking in rats. The European journal of neuroscience. vol 37. issue 6. 2013-08-29. PMID:23320810. |
prior to testing, sch 23390 was administered into the nucleus accumbens (nac) shell (0.0, 0.3, 0.6 μg/side), nac core (0.0, 0.3, 0.6 μg/side), dorsomedial prefrontal cortex (dmpfc; 0.0, 0.2, 2.0 μg/side), ventromedial prefrontal cortex (vmpfc; 0.0, 2.0 μg/side) or basolateral amygdala (bla; 0.0, 1.0, 2.0 μg/side). |
2013-08-29 |
2023-08-12 |
rat |
| C Garcia-Keller, S A Martinez, M A Esparza, F Bollati, P W Kalivas, L M Cancel. Cross-sensitization between cocaine and acute restraint stress is associated with sensitized dopamine but not glutamate release in the nucleus accumbens. The European journal of neuroscience. vol 37. issue 6. 2013-08-29. PMID:23360446. |
here we explore the mechanisms in the nucleus accumbens (nac) whereby an acute restraint stress augments the acute locomotor response to cocaine. |
2013-08-29 |
2023-08-12 |
rat |
| K Ebihara, K Yamamoto, K Ueda, N Koshikawa, M Kobayash. Cholinergic interneurons suppress action potential initiation of medium spiny neurons in rat nucleus accumbens shell. Neuroscience. vol 236. 2013-08-26. PMID:23380504. |
acetylcholine plays a crucial role in the regulation of neural functions, including dopamine release, synaptic activity, and intrinsic electrophysiological properties of the nucleus accumbens (nac) shell. |
2013-08-26 |
2023-08-12 |
rat |