| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deveroux Ferguson, Ja Wook Koo, Jian Feng, Elizabeth Heller, Jacqui Rabkin, Mitra Heshmati, William Renthal, Rachael Neve, Xiaochuan Liu, Ningyi Shao, Vittorio Sartorelli, Li Shen, Eric J Nestle. Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 41. 2013-11-26. PMID:24107942. |
here, we establish an essential role for sirt1 and sirt2 in regulating behavioral responses to cocaine and morphine through actions in the nucleus accumbens (nac), a key brain reward region. |
2013-11-26 |
2023-08-12 |
mouse |
| Marwan N Baliki, Ali Mansour, Alex T Baria, Lejian Huang, Sara E Berger, Howard L Fields, A Vania Apkaria. Parceling human accumbens into putative core and shell dissociates encoding of values for reward and pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 41. 2013-11-26. PMID:24107968. |
in addition to their well-established role in signaling rewarding outcomes and reward-predictive cues and in mediating positive reinforcement, there is growing evidence that nucleus accumbens (nac) neurons also signal aversive events and cues that predict them. |
2013-11-26 |
2023-08-12 |
human |
| Allison J Brager, J Christopher Ehlen, Oscar Castanon-Cervantes, Divya Natarajan, Patrick Delisser, Alec J Davidson, Ketema N Pau. Sleep loss and the inflammatory response in mice under chronic environmental circadian disruption. PloS one. vol 8. issue 5. 2013-11-25. PMID:23696854. |
fos-immunoreactivity (ir) was quantified in sleep-wake regulatory areas: the nucleus accumbens (nac), basal forebrain (bf), and medial preoptic area (mnpo). |
2013-11-25 |
2023-08-12 |
mouse |
| Drew D Kiraly, Natali E Nemirovsky, Taylor P LaRese, Seven E Tomek, Stephanie L Yahn, M Foster Olive, Betty A Eipper, Richard E Main. Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration. Molecular pharmacology. vol 84. issue 4. 2013-11-25. PMID:23894151. |
chronic treatment with cocaine increases dendritic spine density in the nucleus accumbens (nac) of rodents and primates. |
2013-11-25 |
2023-08-12 |
mouse |
| Zisis Bimpisidis, Maria Antonietta De Luca, Augusta Pisanu, Gaetano Di Chiar. Lesion of medial prefrontal dopamine terminals abolishes habituation of accumbens shell dopamine responsiveness to taste stimuli. The European journal of neuroscience. vol 37. issue 4. 2013-11-04. PMID:23216547. |
taste stimuli increase extracellular dopamine (da) in the nucleus accumbens (nac) and in the medial prefrontal cortex (mpfc). |
2013-11-04 |
2023-08-12 |
rat |
| Yukie Kawahara, Fumi Kaneko, Makiko Yamada, Yuki Kishikawa, Hiroshi Kawahara, Akinori Nish. Food reward-sensitive interaction of ghrelin and opioid receptor pathways in mesolimbic dopamine system. Neuropharmacology. vol 67. 2013-11-04. PMID:23220294. |
extracellular dopamine levels were quantified in the nucleus accumbens (nac) and receptor-specific compounds were infused into the ventral tegmental area (vta) using dual-probe microdialysis. |
2013-11-04 |
2023-08-12 |
rat |
| Stéphanie Alaux-Cantin, Vincent Warnault, Rémi Legastelois, Béatrice Botia, Olivier Pierrefiche, Catherine Vilpoux, Mickaël Naassil. Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens. Neuropharmacology. vol 67. 2013-11-04. PMID:23287538. |
as the nucleus accumbens (nac) is particularly involved in addictive behavior, we analyzed iei-induced long-term neuroadaptations in the nac using c-fos immunohistochemistry and an array of neurotransmission-related genes. |
2013-11-04 |
2023-08-12 |
rat |
| Pedro A Pereira, Diana Santos, João Neves, M Dulce Madeira, Manuel M Paula-Barbos. Nerve growth factor retrieves neuropeptide Y and cholinergic immunoreactivity in the nucleus accumbens of old rats. Neurobiology of aging. vol 34. issue 8. 2013-11-04. PMID:23540942. |
the nucleus accumbens (nac) contains high levels of neuropeptide y (npy), which is involved in the regulation of functions and behaviors that deteriorate with aging. |
2013-11-04 |
2023-08-12 |
rat |
| Jing Liang, Si-Si Ma, Yi-Jing Li, Xing-Jie Ping, Ling Hu, Cai-Lian Cu. Dynamic changes of tyrosine hydroxylase and dopamine concentrations in the ventral tegmental area-nucleus accumbens projection during the expression of morphine-induced conditioned place preference in rats. Neurochemical research. vol 37. issue 7. 2013-10-31. PMID:22396106. |
our previous study demonstrated that morphine dose- and time-dependently elevated dopamine (da) concentrations in the nucleus accumbens (nac) during the expression of morphine-induced conditioned place preference (cpp) in rats. |
2013-10-31 |
2023-08-12 |
rat |
| Pauline Belujon, Mary H Patton, Anthony A Grac. Disruption of prefrontal cortical-hippocampal balance in a developmental model of schizophrenia: reversal by sulpiride. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:23067577. |
the nucleus accumbens (nac) receives converging inputs from the medial prefrontal cortex (mpfc) and the hippocampus which have competitive interactions in the nac to influence motivational drive. |
2013-10-31 |
2023-08-12 |
Not clear |
| Devesh Mishra, Karima Chergu. Ethanol inhibits excitatory neurotransmission in the nucleus accumbens of adolescent mice through GABAA and GABAB receptors. Addiction biology. vol 18. issue 4. 2013-10-29. PMID:21790906. |
we, therefore, assessed age differences in the ability of ethanol to modulate glutamatergic synaptic transmission in the mouse nucleus accumbens (nac), a brain region importantly involved in reward mechanisms. |
2013-10-29 |
2023-08-12 |
mouse |
| Zheng-Xiong Xi, Xia Li, Jie Li, Xiao-Qing Peng, Rui Song, József Gaál, Eliot L Gardne. Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. Addiction biology. vol 18. issue 4. 2013-10-29. PMID:22913325. |
recent research demonstrates that cue-induced cocaine seeking appears to parallel increased da d3 , but not d1 or d2 , receptor expression in the nucleus accumbens (nac) of rats over time of withdrawal, suggesting possible involvement of d3 receptors (d3 rs) in incubation of cocaine craving. |
2013-10-29 |
2023-08-12 |
rat |
| Joanna I Giza, Yonwoo Jung, Rachel A Jeffrey, Nichole M Neugebauer, Marina R Picciotto, Thomas Biedere. The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 4. 2013-10-29. PMID:23169347. |
our studies now reveal that the loss of syncam 1 in knockout (ko) mice reduces excitatory synapse number in nucleus accumbens (nac). |
2013-10-29 |
2023-08-12 |
mouse |
| Eun-Sol Jung, Hyo Jin Lee, Hye-Ri Sim, Ja-Hyun Bai. Cocaine-induced behavioral sensitization in mice: effects of microinjection of dopamine d2 receptor antagonist into the nucleus accumbens. Experimental neurobiology. vol 22. issue 3. 2013-10-29. PMID:24167417. |
to determine the role of dopamine d2 receptor (d2r) in the nucleus accumbens (nac) core in cocaine-induced behavioral sensitization, d2r antagonist, raclopride was bilaterally microinjected (2.5 or 5 nmol) into the nac core of wt and d2r(-/-) mice and the initiation and expression phase of cocaine-mediated locomotor sensitization were analyzed. |
2013-10-29 |
2023-08-12 |
mouse |
| Michihiko Iijima, Hiroyuki Koike, Shigeyuki Chak. Effect of an mGlu2/3 receptor antagonist on depressive behavior induced by withdrawal from chronic treatment with methamphetamine. Behavioural brain research. vol 246. 2013-10-28. PMID:23473878. |
moreover, we found that the microinjection of ly341495 into the nucleus accumbens (nac) also counteracted the increase in the immobility time caused by withdrawal from chronic treatment with map. |
2013-10-28 |
2023-08-12 |
rat |
| Susana Peciña, Kent C Berridg. Dopamine or opioid stimulation of nucleus accumbens similarly amplify cue-triggered 'wanting' for reward: entire core and medial shell mapped as substrates for PIT enhancement. The European journal of neuroscience. vol 37. issue 9. 2013-10-28. PMID:23495790. |
the answer may be the level of incentive salience ('wanting') that is dynamically generated by mesocorticolimbic brain systems, influenced especially by dopamine and opioid neurotransmission in the nucleus accumbens (nac) at that moment. |
2013-10-28 |
2023-08-12 |
Not clear |
| Omar Ouachikh, Wisam Dieb, Franck Durif, Aziz Hafid. Differential behavioral reinforcement effects of dopamine receptor agonists in the rat with bilateral lesion of the posterior ventral tegmental area. Behavioural brain research. vol 252. 2013-10-28. PMID:23727149. |
the posterior (p)vta, which project to the nucleus accumbens (nac) constitutes the major dopamine neuronal circuitry implicated in addictive disorders. |
2013-10-28 |
2023-08-12 |
rat |
| Danielle M Judice-Daher, José Lino O Buen. Lesions of the nucleus accumbens disrupt reinforcement omission effects in rats. Behavioural brain research. vol 252. 2013-10-28. PMID:23796973. |
it has been suggested the interaction between the amygdala and the nucleus accumbens (nac) is important to the modulation of motivational processes. |
2013-10-28 |
2023-08-12 |
human |
| Christina Bocklisch, Vincent Pascoli, Jovi C Y Wong, David R C House, Cédric Yvon, Mathias de Roo, Kelly R Tan, Christian Lüsche. Cocaine disinhibits dopamine neurons by potentiation of GABA transmission in the ventral tegmental area. Science (New York, N.Y.). vol 341. issue 6153. 2013-10-28. PMID:24072923. |
much research has focused on excitatory transmission in the ventral tegmental area (vta) and the nucleus accumbens (nac). |
2013-10-28 |
2023-08-12 |
Not clear |
| Sara Sadeghi, Zahra Reisi, Hassan Azhdari-Zarmehri, Abbas Haghparas. Involvement of orexin-1 receptors in the ventral tegmental area and the nucleus accumbens in antinociception induced by lateral hypothalamus stimulation in rats. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23474374. |
in this study, we tried to evaluate the involvement of orexin-1 receptors in the ventral tegmental area (vta) and the nucleus accumbens (nac) on antinociceptive responses induced by lh stimulation in rats. |
2013-10-23 |
2023-08-12 |
rat |