| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F C Zhou, E C Azmiti. Laminin facilitates and guides fiber growth of transplanted neurons in adult brain. Journal of chemical neuroanatomy. vol 1. issue 3. 1989-11-17. PMID:3267344. |
in the fetal brain, the raphe area of the rostral rhombencephalon is rich in serotonergic (5-ht) neurons; the rostral ventral mesencephalon is rich in dopamine (da) neurons, while the lateral rhombencephalon is rich in norepinephrinergic (ne) neurons. |
1989-11-17 |
2023-08-11 |
Not clear |
| J De Keyser, J P De Backer, G Ebinger, G Vauqueli. [3H]GBR 12935 binding to dopamine uptake sites in the human brain. Journal of neurochemistry. vol 53. issue 5. 1989-11-15. PMID:2795007. |
binding of [3h]gbr 12935 to dopamine uptake sites was lost in the nucleus caudatus ipsilateral to ventral midbrain infarctions, confirming their location on nigrostriatal nerve endings. |
1989-11-15 |
2023-08-11 |
human |
| G F Steinfels, S W Tam, L Coo. Electrophysiological effects of selective sigma-receptor agonists, antagonists, and the selective phencyclidine receptor agonist MK-801 on midbrain dopamine neurons. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 2. issue 3. 1989-11-13. PMID:2571340. |
electrophysiological effects of selective sigma-receptor agonists, antagonists, and the selective phencyclidine receptor agonist mk-801 on midbrain dopamine neurons. |
1989-11-13 |
2023-08-11 |
Not clear |
| A Romaniuk, M Strzelczuk, M Wieczore. Serotonin depletion with P-chlorophenylalanine in the cat: effects on carbachol-induced defensive behavior and regional brain amine content. Acta neurobiologiae experimentalis. vol 49. issue 4. 1989-11-08. PMID:2529739. |
besides important depletion of 5-ht in the anterior and posterior hypothalamus, midbrain and amygdala, and 5-hydroxyindoleacetic acid (5-hiaa) in the anterior and posterior hypothalamus and midbrain, dopamine (da) level significantly increased in the amygdala and posterior hypothalamus with tendency to increase in the anterior hypothalamus and midbrain. |
1989-11-08 |
2023-08-11 |
cat |
| N Mons, F Tison, M Geffar. Identification of L-dopa-dopamine and L-dopa cell bodies in the rat mesencephalic dopaminergic cell systems. Synapse (New York, N.Y.). vol 4. issue 2. 1989-10-19. PMID:2781469. |
an immunocytochemical technique for simultaneously visualizing two different antigens, dihydroxyphenylalanine (l-dopa) and dopamine (da), has been used to investigate the presence of cell bodies containing both compounds l-dopa and da and those having only l-dopa in rat mesencephalon areas. |
1989-10-19 |
2023-08-11 |
mouse |
| P Danias, W J Nicklas, S Ofori, J Shen, C Mytilineo. Mesencephalic dopamine neurons become less sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity during development in vitro. Journal of neurochemistry. vol 53. issue 4. 1989-10-12. PMID:2788714. |
the in vitro development of monoamine oxidase (mao) activity and [3h]dopamine (da) uptake capacity of dissociated cell cultures from rat embryo mesencephalon were correlated with the potency of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) and 1-methyl-4-phenylpyridine (mpp+) neurotoxicity. |
1989-10-12 |
2023-08-11 |
rat |
| J Grenhoff, T H Svensso. Clonidine modulates dopamine cell firing in rat ventral tegmental area. European journal of pharmacology. vol 165. issue 1. 1989-10-05. PMID:2569981. |
on the activity of single, identified dopamine neurons in the ventral tegmental area of the mesencephalon was studied in chloral hydrate-anesthetized male rats. |
1989-10-05 |
2023-08-11 |
rat |
| K F Manaye, P K Sonsalla, G Barnett, R E Heikkila, D J Woodward, W K Smith, D C Germa. 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-induced degeneration of mesostriatal dopaminergic neurons in the mouse: biochemical and neuroanatomical studies. Brain research. vol 491. issue 2. 1989-09-22. PMID:2765888. |
moderate doses of 2'ch3-mptp produced a greater depletion of dopamine (da) in the striatum (45%) than in the nucleus accumbens (23%), and in these same animals, there was a 35% loss of midbrain da neurons. |
1989-09-22 |
2023-08-11 |
mouse |
| Q Ahmad, Z Meral. Behavioral and neurochemical effects of amfonelic acid on the spontaneously diabetic Wistar-BB rat: implications of impaired dopamine function. Progress in neuro-psychopharmacology & biological psychiatry. vol 13. issue 3-4. 1989-08-21. PMID:2748878. |
results obtained indicated that the sdr: i) is less sensitive to the behavioral effects of afa than the controls; ii) following afa treatment (1.0 mg/kg) a significantly greater depletion of dopamine in the striatum, hypothalamus, midbrain and olfactory bulbs as well as striatal norepinephrine was observed in the sdr as compared to controls. |
1989-08-21 |
2023-08-11 |
rat |
| R F Gariano, P M Grove. A mechanism for the involvement of colocalized neuropeptides in the actions of antipsychotic drugs. Biological psychiatry. vol 26. issue 3. 1989-08-17. PMID:2568135. |
evidence has accumulated to implicate neuropeptides localized within midbrain dopamine neurons (cholecystokinin, neurotensin, acetylcholinesterase) in synaptic transmission, mental disease, and pharmacotherapy. |
1989-08-17 |
2023-08-11 |
Not clear |
| R P Dilts, P W Kaliva. Autoradiographic localization of mu-opioid and neurotensin receptors within the mesolimbic dopamine system. Brain research. vol 488. issue 1-2. 1989-08-14. PMID:2545303. |
unilateral lesions of dopamine perikarya produced by 6-hydroxydopamine (6-ohda), administered in the ventral mesencephalon, produced a unilateral loss of specific neurotensin binding (65%), but did not affect mu-opioid receptor density or distribution. |
1989-08-14 |
2023-08-11 |
Not clear |
| K Niijima, M Yoshid. Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251582. |
these facts indicate: (1) the tpc-derived circling behavior is mediated by the dopamine system, (2) the chemical stimulation of tpc by ka might produce an activation of midbrain dopamine neurons by excitatory tpc efferents to the dopamine neurons and enhance the dopamine turnover in the nucleus accumbens as well as in the striatum, (3) the excitatory tpc efferents may be muscarinic cholinergic in accordance with previous reports. |
1989-07-31 |
2023-08-11 |
rat |
| B K Nelson, W S Brightwell, B J Taylor, A Khan, J R Burg, E F Krieg, V J Massar. Behavioral teratology investigation of 1-propanol administered by inhalation to rats. Neurotoxicology and teratology. vol 11. issue 2. 1989-07-21. PMID:2733653. |
brains from 10 rats per group were dissected into cerebrum, cerebellum, brainstem, and midbrain, and were assayed for protein, acetylcholine, dopamine, norepinephrine, serotonin, beta-endorphin, met-enkephalin, and substance p. overall, the results indicate that exposure to high concentrations of 1-propanol can affect fertility in exposed males (only 2 of 17 produced litters), but there were no consistent effects seen in the behavioral or neurochemical tests measured. |
1989-07-21 |
2023-08-11 |
human |
| H Amano, Y Goshima, N Akema, H Ueda, T Kubo, Y Mis. Effects of acute nicotine on catecholamine turnover in various rat brain regions. Journal of pharmacobio-dynamics. vol 12. issue 1. 1989-07-10. PMID:2724049. |
acute effects of in vivo nicotine application on turnover rates of noradrenaline (na), adrenaline (ad) and dopamine (da) in rat occipital cortex, hippocampus, striatum, hypothalamus, thalamus, midbrain, pons/medulla and cerebellum were examined by determining the amine concentrations by high performance liquid chromatography. |
1989-07-10 |
2023-08-11 |
rat |
| L Ugedo, J Grenhoff, T H Svensso. Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. Psychopharmacology. vol 98. issue 1. 1989-07-07. PMID:2524859. |
ritanserin, a 5-ht2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. |
1989-07-07 |
2023-08-11 |
rat |
| L Ugedo, J Grenhoff, T H Svensso. Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. Psychopharmacology. vol 98. issue 1. 1989-07-07. PMID:2524859. |
the effect of systemic administration of ritanserin (r 55667), a 5-hydroxytryptamine (5-ht2) receptor antagonist, on midbrain dopamine (da) neurons was studied with single cell recording techniques in the chloral hydrate anesthetized male rat. |
1989-07-07 |
2023-08-11 |
rat |
| E Esposito, B S Bunne. The effect of acute and chronic treatment with SCH 23390 on the spontaneous activity of midbrain dopamine neurons. European journal of pharmacology. vol 162. issue 1. 1989-07-06. PMID:2656273. |
the effect of acute and chronic treatment with sch 23390 on the spontaneous activity of midbrain dopamine neurons. |
1989-07-06 |
2023-08-11 |
rat |
| J Engele, C Pilgrim, M Kirsch, I Reiser. Different developmental potentials of diencephalic and mesencephalic dopaminergic neurons in vitro. Brain research. vol 483. issue 1. 1989-06-06. PMID:2565148. |
morphological and functional differentiation of dopamine (da) neurons was compared in dissociated cultures from gestational day 14 rat mesencephalon and diencephalon. |
1989-06-06 |
2023-08-11 |
rat |
| J M Goldstein, L C Litwi. Spontaneous activity of A9 and A10 dopamine neurons after acute and chronic administration of the selective dopamine D-1 receptor antagonist SCH 23390. European journal of pharmacology. vol 155. issue 1-2. 1989-06-06. PMID:2907487. |
the effects of acute and chronic treatment with the selective dopamine (da) d-1 antagonist sch 23390 on the population response of midbrain da cells were determined. |
1989-06-06 |
2023-08-11 |
Not clear |
| N E Andén, J Grenhoff, T H Svensso. Does treatment with haloperidol for 3 weeks produce depolarization block in midbrain dopamine neurons of unanaesthetized rats? Psychopharmacology. vol 96. issue 4. 1989-06-02. PMID:3149782. |
does treatment with haloperidol for 3 weeks produce depolarization block in midbrain dopamine neurons of unanaesthetized rats? |
1989-06-02 |
2023-08-11 |
rat |