| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Brené, N Lindefors, M Herrera-Marschitz, H Persso. Expression of dopamine D2 receptor and choline acetyltransferase mRNA in the dopamine deafferented rat caudate-putamen. Experimental brain research. vol 83. issue 1. 1991-04-16. PMID:2150048. |
d2r mrna expressing neurons were seen in regions which are known to be heavily innervated by midbrain dopamine fibers such as caudate-putamen, nucleus accumbens and olfactory tubercle. |
1991-04-16 |
2023-08-11 |
rat |
| S Brené, N Lindefors, M Herrera-Marschitz, H Persso. Expression of dopamine D2 receptor and choline acetyltransferase mRNA in the dopamine deafferented rat caudate-putamen. Experimental brain research. vol 83. issue 1. 1991-04-16. PMID:2150048. |
after a unilateral lesion of midbrain dopamine neurons, no change in the level of either d2r or chat mrna were seen in the large size intrinsic cholinergic neurons in caudate-putamen. |
1991-04-16 |
2023-08-11 |
rat |
| S Brené, N Lindefors, M Herrera-Marschitz, H Persso. Expression of dopamine D2 receptor and choline acetyltransferase mRNA in the dopamine deafferented rat caudate-putamen. Experimental brain research. vol 83. issue 1. 1991-04-16. PMID:2150048. |
thus, it appears that midbrain dopamine deafferentation causes an increase in d2r mrna expression in a subpopulation of medium size neurons in the lateral caudate-putamen. |
1991-04-16 |
2023-08-11 |
rat |
| G L Bernardini, S G Speciale, D C Germa. Increased midbrain dopaminergic cell activity following 2'CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study. Brain research. vol 527. issue 1. 1991-03-19. PMID:1980838. |
several days after the administration of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'ch3-mptp) to the balb/cj mouse there is a loss of midbrain dopaminergic neurons, a reduction of forebrain dopamine (da) content, and an elevation in forebrain da turnover. |
1991-03-19 |
2023-08-11 |
mouse |
| F S Messih. Effect of methionine on regional CDF-1 mouse brain monoamines. Drug and chemical toxicology. vol 13. issue 4. 1991-03-12. PMID:2279463. |
the results suggest methionine-mediated decreases of dopamine turnover in the hippocampus and medulla compared to increases of serotonin turnover in the cerebral cortex and midbrain regions. |
1991-03-12 |
2023-08-11 |
mouse |
| J Luthman, E Brodin, E Sundström, B Wiehage. Studies on brain monoamine and neuropeptide systems after neonatal intracerebroventricular 6-hydroxydopamine treatment. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 8. issue 5. 1991-03-08. PMID:1704172. |
a neonatal intracerebroventricular 6-hydroxydopamine treatment thus leads to a lesion of dopamine neurons in the mesencephalon with extensive loss of dopamine fibers in several forebrain areas, while localized serotonin fiber sprouting is induced in striatum. |
1991-03-08 |
2023-08-11 |
rat |
| H Mount, P Boksa, I Chaudieu, R Quirio. Phencyclidine and related compounds evoked [3H]dopamine release from rat mesencephalic cell cultures by a mechanism independent of the phencyclidine receptor, sigma binding site, or dopamine uptake site. Canadian journal of physiology and pharmacology. vol 68. issue 9. 1991-03-04. PMID:1980428. |
at concentrations greater than or equal to 100 microm, phencyclidine (pcp), n-(1-(2-thienyl)-cyclohexyl)piperidine (tcp), and mk-801 induced [3h]dopamine release from dissociated cell cultures of rat mesencephalon. |
1991-03-04 |
2023-08-11 |
rat |
| M L Fiszman, A Zuddas, M I Masana, J L Barker, U di Porzi. Dopamine synthesis precedes dopamine uptake in embryonic rat mesencephalic neurons. Journal of neurochemistry. vol 56. issue 2. 1991-02-26. PMID:1671084. |
we have measured [3h]dopamine ([3h]da) uptake and tyrosine hydroxylase-immunopositive immunostaining in cells acutely dissociated from the embryonic ventral mesencephalon (msc). |
1991-02-26 |
2023-08-11 |
rat |
| M Takasuna, T Iwasak. [Right/left discrimination learning in rat pups neonatally treated with 6-hydroxydopamine]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 10. issue 2. 1991-01-17. PMID:2123587. |
biochemical assay confirmed a marked depletion of brain dopamine contents in striatum, cortex and midbrain with thalamus in 6-ohda-treated rats. |
1991-01-17 |
2023-08-11 |
rat |
| B Knüsel, L E Burton, F M Longo, W C Mobley, V E Koliatsos, D L Price, F Heft. Trophic actions of recombinant human nerve growth factor on cultured rat embryonic CNS cells. Experimental neurology. vol 110. issue 3. 1991-01-11. PMID:2249737. |
at concentrations of up to 10 micrograms/ml, rhngf did not significantly increase uptake of dopamine into cultures of ventral mesencephalon. |
1991-01-11 |
2023-08-11 |
mouse |
| N Lindefors, S Brené, M Herrera-Marschitz, H Persso. Regulation of neuropeptide Y gene expression in rat brain. Annals of the New York Academy of Sciences. vol 611. 1991-01-10. PMID:1978997. |
transsynaptic regulation of npy gene expression was specifically studied in caudate-putamen and frontoparietal (somatosensory) cortex of rats with unilateral lesion of midbrain dopamine neurons and in sham-injected animals. |
1991-01-10 |
2023-08-11 |
rat |
| N Lindefors, S Brené, M Herrera-Marschitz, H Persso. Regulation of neuropeptide Y gene expression in rat brain. Annals of the New York Academy of Sciences. vol 611. 1991-01-10. PMID:1978997. |
npy mrna expression in these two brain regions and the regulation of midbrain dopamine neurons were compared with that of som, ppt, cck and gad mrna expression. |
1991-01-10 |
2023-08-11 |
rat |
| D Orosz, J P Bennet. Baseline and apomorphine-induced extracellular levels of nigral substance P are increased in an animal model of Parkinson's disease. European journal of pharmacology. vol 182. issue 3. 1990-12-12. PMID:1699767. |
parkinson's disease arises from extensive premature loss of dopamine (da)-utilizing midbrain neurons whose axons form the nigrostriatal pathway and densely innervate the striatum (caudate-putamen). |
1990-12-12 |
2023-08-11 |
rat |
| N Lindefors, U Ungersted. Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons. Neuroscience letters. vol 115. issue 2-3. 1990-12-12. PMID:1978265. |
bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons. |
1990-12-12 |
2023-08-11 |
rat |
| B K Nelson, W S Brightwell, E F Krie. Developmental toxicology of industrial alcohols: a summary of 13 alcohols administered by inhalation to rats. Toxicology and industrial health. vol 6. issue 3-4. 1990-12-11. PMID:2237924. |
additionally, brains were removed from 10 offspring per group at 21 days of age, and were dissected into cerebrum, cerebellum, brainstem, and midbrain; these samples were assayed for steady-state levels of protein and the neurotransmitters acetylcholine, dopamine, norepinephrine, 5-hydroxytryptamine (serotonin), substance p, b-endorphin, and met-enkephalin. |
1990-12-11 |
2023-08-11 |
rat |
| M Schalling, K Friberg, K Seroogy, P Riederer, E Bird, S N Schiffmann, P Mailleux, J J Vanderhaeghen, S Kuga, M Goldstei. Analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 21. 1990-12-07. PMID:1978324. |
analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia. |
1990-12-07 |
2023-08-11 |
human |
| M D Kelland, A S Freeman, P A LeWitt, L A Chiod. Effects of (+)-4-propyl-9-hydroxynaphthoxazine on midbrain dopamine neurons: an electrophysiological study. The Journal of pharmacology and experimental therapeutics. vol 255. issue 1. 1990-11-21. PMID:1976800. |
effects of (+)-4-propyl-9-hydroxynaphthoxazine on midbrain dopamine neurons: an electrophysiological study. |
1990-11-21 |
2023-08-11 |
rat |
| A A Grac. Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain research. vol 524. issue 1. 1990-10-26. PMID:2400930. |
evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. |
1990-10-26 |
2023-08-11 |
rat |
| A A Grac. Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain research. vol 524. issue 1. 1990-10-26. PMID:2400930. |
the regulation of spike generation in rat midbrain dopamine (da) neurons was investigated using in vitro intracellular recordings. |
1990-10-26 |
2023-08-11 |
rat |
| F Kawat. [Studies on monoamine metabolism in the rat brain with overdosage of manganese]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. vol 44. issue 2. 1990-10-24. PMID:2402098. |
1) in the mn-loaded rats, the concentration of dopamine (da) was significantly decreased in the nucleus caudatus-putamen (c/p)(p less than 0.05), the thalamus (p less than 0.05) and in the mesencephalon (me) (p less than 0.001), while that of homovanillic acid decreased in the c/p (p less than 0.05). |
1990-10-24 |
2023-08-11 |
rat |